24 research outputs found
The cultural diffusion of hockey in Montreal, 1890-1910.
- Author
- Publication venue
- 'University of Windsor Leddy Library'
- Publication date
- 01/01/1986
- Field of study
Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1986 .V545. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.H.K.)--University of Windsor (Canada), 1986
La naissance d'un sport organisé au Canada : le hockey à Montréal, 1875-1917
- Author
- Publication venue
- Bibliotheque de l' Universite Laval
- Publication date
- 01/01/2001
- Field of study
Québec Université Laval, Bibliothèque 201
Évaluation des risques que comporte l’exposition aux gras trans au Canada
- Author
- Publication venue
- 'IntechOpen'
- Publication date
- 01/01/2012
- Field of study
Trans fats are undesirable because they raise LDL-cholesterol and lower HDL-cholesterol levels in the blood, which can lead to an increased risk of coronary heart disease. In the mid-1990\u27s, researchers estimated that Canadians had one of the highest average trans fat intakes in the world, estimated to be approximately 3.7% of energy. The World Health Organization recommends that average intakes of trans fats should be less than 1% of total energy. As such Canada has pursued a multi-faceted approach to decrease trans fat levels in Canadian foods. Initiatives undertaken include: mandatory nutrition labelling, the establishment of a multi-stakeholder Trans Fat Task Force to develop recommendations and strategies to eliminate trans fat in Canadian foods, and most recently the monitoring of industry\u27s efforts in reducing trans fats from their food products. Collectively, these initiatives have proven successful as average trans fat intakes have been reduced to 1.42% of overall energy. Further reductions in trans fat levels in the Canadian food supply are needed to meet the target of 1% of energy, the associated public health objectives, and the protection of vulnerable populations.Les gras trans sont indésirables, car ils augmentent la concentration sanguine en cholestérol à lipoprotéines de faible densité et abaissent celle en cholestérol à lipoprotéines de haute densité, ce qui peut mener à un risque accru de coronaropathie. Au milieu des années 1990, les chercheurs ont estimé quʹau sein de la population canadienne les apports en gras trans comptaient au nombre des plus élevés au monde en atteignant environ 3,7% de l’apport énergétique. Selon la recommandation de l’Organisation mondiale de la santé, l’apport moyen en gras trans devrait être inférieur à 1% de l’apport énergétique total. Par conséquent, le Canada a adopté une démarche à volets multiples visant à diminuer la teneur en gras trans des aliments canadiens. Les initiatives entreprises sont les suivantes: l’étiquetage nutritionnel obligatoire, l’établissement dʹun groupe de travail multilatéral, soit le Groupe d’étude surles graisses trans, dans le but d’élaborer des recommandations et des stratégies ciblant l’élimination des gras trans dans l’approvisionnement alimentaire canadien et, plus récemment, la surveillance des efforts investis par l’industrie dans la diminution des gras trans contenus dans ses produits. De concert, ces initiatives ont été couronnées de succès alors que l’apport moyen en gras trans a atteint 1,42% de l’apport énergétique total. D’autres réductions de la teneur en gras trans de l’approvisionnement alimentaire au Canada sont essentielles pour atteindre pleinement la cible de 1% de l’apport énergétique ainsi que les objectifs afférents en matière de santé publique et de protection des populations vulnérables
CMS physics technical design report : Addendum on high density QCD with heavy ions
- Author
- 1 A. HEIKKINEN
- 1 A. T. LAASANEN
- 1 E. LOCCI
- 1 K. MAESHIMA
- 1 L. VAN LANCKER
- 1 R. DEMINA
- 1 V. VELEV
- 2 R. L. IOPE
- 28 P. LECOQ
- 3 A. DEBRAINE
- 45 W. CLARIDA
- 5 Y. PATOIS
- 6 C. MAAZOUZI
- 6 P. GRAEHLING
- 6 S. MOREAU
- 8 P. KOVESARKI
- 9 S. CHATTERJI
- A. A. SHAH
- A. ADOLF
- A. AERTS
- A. AFFOLDER
- A. ALBERT
- A. ALEKHIN
- A. ALI
- A. ALLEN
- A. ANISIMOV
- A. ANJUM
- A. APRESYAN
- A. ARTAMONOV
- A. ASHIMOVA
- A. ASKEW
- A. AURISANO
- A. AVETISYAN
- A. AVEZOV
- A. AZMAN
- A. B. LODGE
- A. BALDOV
- A. BALL
- A. BARTOLONI
- A. BASHIR
- A. BASTI
- A. BAUMBAUGH
- A. BAZAN
- A. BEAN
- A. BELKOV
- A. BHATTI
- A. BJORKEBO
- A. BOCCI
- A. BODEK
- A. BOIANO
- A. BONNEVAUX
- A. BORNHEIM
- A. BOUBEKEUR
- A. BRANSON
- A. BRASOLIN
- A. BREZ
- A. BUJAK
- A. BUSATA
- A. BÖHM
- A. C. BENVENUTI
- A. C. LE BIHAN
- A. CALDERON
- A. CANDELORI
- A. CANER
- A. CATTAI
- A. CECILIA
- A. CIMMINO
- A. CLEMENTE
- A. COLALEO
- A. COLOMBO
- A. CONDE GARCIA
- A. COOPER
- A. CYZ
- A. D. PRESLAND
- A. DAVID TINOCO MENDES
- A. DE BENEDETTI
- A. DE MIN
- A. DE ROECK
- A. DELGADO PERIS
- A. DIERLAMM
- A. DIMITROV
- A. DOLGOPOLOV
- A. DOMENICONI
- A. DOMINGUEZ
- A. DROZDETSKIY
- A. ELLIOTT PEISERT
- A. ERSHOV
- A. EVERETT
- A. F. GARFINKEL
- A. FEDOROV
- A. FENYVESI
- A. FERRANDO
- A. FILINE
- A. FLOSSDORF
- A. FREY
- A. FUCCI
- A. FURGERI
- A. GADDI
- A. GAGGELLI
- A. GARMASH
- A. GHEZZI
- A. GIAMMANCO
- A. GIASSI
- A. GIRALDO
- A. GIVERNAUD
- A. GO
- A. GODIZOV
- A. GOLUNOV
- A. GOLYASH
- A. GOUSSIOU
- A. GRELLI
- A. GRESELE
- A. GRIBUSHIN
- A. GRIGGIO
- A. GRITSAN
- A. GURTU
- A. HAHN
- A. HEERING
- A. HEISTER
- A. HEKTOR
- A. HERVÉ
- A. HOLZNER
- A. HONKANEN
- A. HONMA
- A. HRISTOV
- A. I. LEBEDEV
- A. INYAKIN
- A. IORDANOVA
- A. IVANOV
- A. J. BELL
- A. J. MADDOX
- A. JAIN
- A. K. MOHANTY
- A. K. SRIVASTAVA
- A. KALININ
- A. KALINOWSKI
- A. KAMAL
- A. KAMENEV
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- A. KHMELNIKOV
- A. KHOMICH
- A. KHUGAEV
- A. KOIMAS
- A. KOPECKY
- A. KORABLEV
- A. KORPELA
- A. KORYTOV
- A. KRAAN
- A. KRINITSYN
- A. KROKHOTIN
- A. KRUSE
- A. KRYUKOV
- A. KUBIK
- A. KUMAR
- A. KUMAR
- A. KURENKOV
- A. KURONEN
- A. KYRIAKIS
- A. L. LINTERN
- A. L. STONE
- A. LA MONACA
- A. LANARO
- A. LANEV
- A. LASZLO
- A. LATH
- A. LEDOVSKOY
- A. LEVINE
- A. LINN
- A. LISTER
- A. LITOMIN
- A. LOPEZ
- A. LOPEZ GARCIA
- A. LOPEZ VIRTO
- A. LOUNIS
- A. LUTHRA
- A. LYONNET
- A. M. BERGDOLT
- A. M. BRETT
- A. M. FOMENKO
- A. M. JAN
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- A. MACCHIOLO
- A. MACHARD
- A. MACPHERSON
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- A. MALAKHOV
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- A. MOSHAII
- A. MZHAVIA
- A. NARDULLI
- A. NAYAK
- A. NEVIANI
- A. NIKITENKO
- A. NOWACK
- A. OH
- A. ONNELA
- A. ORLOV
- A. OSMAN
- A. OSTAPTCHOUK
- A. OULIANOV
- A. P. R. GAY
- A. PACCAGNELLA
- A. PALLARÈS
- A. PALMA
- A. PANAGIOTOU
- A. PAOLOZZI
- A. PAOLUCCI
- A. PAPADAKIS
- A. PAPAGEORGIOU
- A. PARENTI
- A. PARUSSA
- A. PASHENKOV
- A. PASTSYAK
- A. PATINO REVUELTA
- A. PATINO REVUELTA
- A. PAYN
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- A. PETRILLI
- A. PETROSYAN
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- A. PETRUNIN
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- A. POMPILI
- A. POMPOS
- A. POZDNYAKOV
- A. PROFETI
- A. PULLIA
- A. R. ZAFAR
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- A. SANCHEZ HERNANDEZ
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- A. SCHULTZ VON DRATZIG
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- A. SEDOV
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- A. SOURKOV
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- A. STARODUMOV
- A. STRANDLIE
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- A. SZNAJDER
- A. T. MENEGUZZO
- A. T. SERBAN
- A. TAPPER
- A. TAUROK
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- A. THEA
- A. THEEL
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- A. VOLODKO
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- ANATOLY SOLOVEY
- B. A. BARNETT
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- B. ALVER
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- B. J. SMITH
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- C. BERNET
- C. BIINO
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- C. BOTTA
- C. BURGOS LAZARO
- C. C. HUNG
- C. C. WANG
- C. CAMPAGNARI
- C. CASSESE
- C. CERRI
- C. CHARLOT
- C. CHESHKOV
- C. CIVININI
- C. COLLARD
- C. COLLEDANI
- C. COMBARET
- C. D. JONES
- C. DA VIA
- C. DELAERE
- C. DELDICQUE
- C. DRAGOIU
- C. E. GERBER
- C. E. WULZ
- C. EGGEL
- C. EKLUND
- C. FANIN
- C. FELIX
- C. FERNANDEZ BEDOYA
- C. FIGUEROA
- C. FILIPPIDIS
- C. FLOREZ
- C. FOUDAS
- C. GARGIULO
- C. GENTA
- C. GIRERD
- C. GRAB
- C. GRANDI
- C. GREGORY
- C. GRIMM
- C. GUO HU
- C. H. JIANG
- C. H. SHEPHERD THEMISTOCLEOUS
- C. HAJDU
- C. HALLER
- C. HARTL
- C. HILL
- C. HOERMANN
- C. HOF
- C. HOFFMANN
- C. HUMBERTCLAUDE
- C. ILLINGER
- C. J. JENKINS
- C. J. RUSH
- C. JARVIS
- C. JEANNEY
- C. JEONG
- C. JESSOP
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- C. K. LAE
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- C. KAVKA
- C. KUKULIES
- C. L. BLANCO RAMOS
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- C. LEONIDOPOULOS
- C. LESMOND
- C. LIU
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- C. LOURENCO
- C. LUNDSTEDT
- C. LYNCH
- C. M. KUO
- C. M. LEI
- C. MARCHETTINI
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- C. MARIOTTI
- C. MARKOU
- C. MARTIN
- C. MARTINEZ RIVERO
- C. MATTHEY
- C. MAVROMMATIS
- C. MESROPIAN
- C. MINELLI
- C. MIRONOV
- C. N. NGUYEN
- C. NEWMAN HOLMES
- C. NICOLAOU
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- C. OLIVETTO
- C. P. BEETZ
- C. PAILLARD
- C. PAPADIMITROPOULOS
- C. PARIS
- C. PAUS
- C. PERONI
- C. PIASECKI
- C. PICCUT
- C. PINTO
- C. PRESCOTT
- C. PUCCI
- C. R. NEWSOM
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- D. A. GLENZINSKI
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- D. BISELLO
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- D. DE JESUS DAMIAO
- D. DECOTIGNY
- D. DEL RE
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- D. DENEGRI
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- D. DOBUR
- D. DRUZHKIN
- D. DUTTA
- D. DYKSTRA
- D. D’ANGELO
- D. D’ENTERRIA
- D. E. CLARK
- D. ENGH
- D. EVANS
- D. EVANS
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- D. FORTIN
- D. FRANCIA FERRERO
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- D. GOLDIN
- D. GONG
- D. GORBUNOV
- D. GREEN
- D. H. KIM
- D. H. MILLER
- D. H. MOON
- D. HALE
- D. HATTON
- D. HEYDHAUSEN
- D. HOLMES
- D. HORVATH
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- D. HUSS
- D. J. A. COCKERILL
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- D. J. HOFMAN
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- D. J. KONG
- D. JOHNSON
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- D. KROFCHECK
- D. LACROIX
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- D. PITZL
- D. R. CLAES
- D. R. PRICE
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- D. RIZZI
- D. RODRIGUEZ GONZALEZ
- D. ROGULIN
- D. S. YAN
- D. SAMYN
- D. SCHINZEL
- D. SENTENAC
- D. SILLOU
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- D. VINTACHE
- D. W. JANG
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- D. WANG
- D. WARDROPE
- D. WENMAN
- D. WHITE
- D. WIAND
- D. WINN
- D. WRIGHT
- D. ZER ZION
- E. A. ALBAYRAK
- E. A. CHEN
- E. A. DE WOLF
- E. A. WENGER
- E. AGUAYO NAVARRETE
- E. ALAGOZ
- E. ALBERT
- E. ANTTILA
- E. AUFFRAY
- E. BABUCCI
- E. BARBERIS
- E. BARTZ
- E. BATEMAN
- E. BOOS
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- E. BOUGAMONT
- E. BUTZ
- E. C. CHABERT
- E. C. REID
- E. CALVO
- E. CANO
- E. CARRONE
- E. CATACCHINI
- E. CHABANAT
- E. CHRISTOPHEL
- E. CONTI
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- E. DANGELSER
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- E. DELMEIRE
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- E. DUSINBERRE
- E. ESKUT
- E. FILONI
- E. FOCARDI
- E. FORTON
- E. FRIIS
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- S. J. MURRAY
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- S. J. QIAN
- S. J. WATTS
- S. K. KATARIA
- S. K. NAM
- S. K. PARK
- S. KAILAS
- S. KALININ
- S. KAPPLER
- S. KARAEVSKII
- S. KASSELMANN
- S. KHABAROV
- S. KHALATIAN
- S. KLIMENKO
- S. KORJENEVSKI
- S. KOSSIAKOV
- S. KULESHOV
- S. KUNORI
- S. KWAN
- S. KYRE
- S. KYRIAZOPOULOU
- S. KÖNIG
- S. L. BALLY
- S. LACAPRARA
- S. LEHTI
- S. LIEUNARD
- S. LINARI
- S. LINN
- S. LIU
- S. LOS
- S. LOWETTE
- S. LUKYANENKO
- S. LUSIN
- S. M. ABBAS
- S. MAGNI
- S. MALIK
- S. MALVEZZI
- S. MARCELLINI
- S. MARKOV
- S. MARUYAMA
- S. MASELLI
- S. MATTIAZZO
- S. MEDVED
- S. MERSI
- S. METSON
- S. MEYER
- S. MICHAL
- S. MIKOCKI
- S. MOCCIA
- S. MOROVIC
- S. MOVCHAN
- S. MRENNA
- S. MUANZA
- S. MUELLER
- S. MUZAFFAR
- S. MY
- S. NAHN
- S. NATALI
- S. NEEMA
- S. NORDSTROM
- S. NUZZO
- S. OCHESANU
- S. ONISHCHENKO
- S. OTWINOWSKI
- S. OVYN
- S. OZKORUCUKLU
- S. OZTURK
- S. P. H. QUINTON
- S. P. RATTI
- S. PAKTINAT MEHDIABADI
- S. PAOLETTI
- S. PATHAK
- S. PAVLON
- S. PERRIES
- S. PETRUSHANKO
- S. PIPEROV
- S. R. RO
- S. R. WAGNER
- S. RAGAZZI
- S. RAHATLOU
- S. REUCROFT
- S. REYNAUD
- S. REZNIKOV
- S. RUGOVAC
- S. RUTHERFORD
- S. SALA
- S. SARKAR
- S. SCHAEL
- S. SCHMID
- S. SCHNETZER
- S. SCHULZ
- S. SEKMEN
- S. SEMENOV
- S. SENGUPTA
- S. SERGEEV
- S. SGOBBA
- S. SHARMA
- S. SHEVCHENKO
- S. SHMATOV
- S. SHULHA
- S. SILVA
- S. SIMON
- S. SLABOSPITSKY
- S. SOKHA
- S. SOMALWAR
- S. SPANIER
- S. SQUIZZATO
- S. STEINER
- S. STOENCHEV
- S. STOYKOVA
- S. STOYNEV
- S. STROINEY
- S. SWAIN
- S. TAGHAVI
- S. TANWIR
- S. TARONI
- S. TATAURSCHIKOV
- S. TAVERNIER
- S. TISSOT
- S. TKACZYK
- S. TOLAINI
- S. TRALDI
- S. TROITSKY
- S. TROSHIN
- S. TUPPUTI
- S. TZAMARIAS
- S. UDRIOT
- S. V. GLEYZER
- S. V. RUSAKOV
- S. VANINI
- S. VANZETTO
- S. VASIL’EV
- S. VAURYNOVICH
- S. VAVILOV
- S. VENTURA
- S. VILLA
- S. VLACHOS
- S. VOLKOV
- S. W. LEE
- S. W. LI
- S. W. LIN
- S. WAKEFIELD
- S. WALDMEIER WICKI
- S. WANG
- S. WATKINS
- S. WESELER
- S. WHITEHEAD
- S. WIMPENNY
- S. WON
- S. WYNHOFF
- S. X. WU
- S. Y. JUN
- S. Y. JUNG
- S. Y. PARK
- S. ZAVODTHIKOV
- S. ZELEPOUKINE
- S. ZUB
- SIROLI GIAN PIERO
- SUDESHNA BANERJEE
- SUNANDA BANERJEE
- T. ADAMS
- T. ANGUELOV
- T. AZIZ
- T. BAPTY
- T. BARATA MONTEIRO
- T. BARVICH
- T. BAUER
- T. BERGAUER
- T. BOCCALI
- T. BOLTON
- T. BOSE
- T. CAMPORESI
- T. CHRISTIANSEN
- T. DE VISSER
- T. DORIGO
- T. DUPASQUIER
- T. FERGUSON
- T. GERALIS
- T. GOELTZENLICHTER
- T. GORSKI
- T. GRASSI
- T. HAUER
- T. HEBBEKER
- T. HENKES
- T. HERMANNS
- T. HESSELROTH
- T. J. KIM
- T. KACHELHOFFER
- T. KAMON
- T. KELLY
- T. KESKINPALA
- T. KEUTGEN
- T. KOLBERG
- T. KRAMER
- T. KRESS
- T. L. WATTS
- T. LAMPÉN
- T. LE FLOUR
- T. LINDÉN
- T. LOMTADZE
- T. M. SHAW
- T. MA
- T. MAHMOUD
- T. MARTIN
- T. MCCAULEY
- T. MEYER
- T. MIAO
- T. MOERS
- T. MÄENPÄÄ
- T. NUSSBAUM
- T. NYMAN
- T. NÖBAUER
- T. ORIMOTO
- T. P. VANHALA
- T. PIERZCHALA
- T. PUNZ
- T. RODRIGO
- T. ROHE
- T. ROMANTEAU
- T. ROMMERSKIRCHEN
- T. SAKHELASHVILI
- T. SCHREINER
- T. SOBRIER
- T. SPEER
- T. STAPELBERG
- T. TABARELLI DE FATIS
- T. TODOROV
- T. TOMEI
- T. TOOLE
- T. TUUVA
- T. VIRDEE
- T. WEILER
- T. WILDISH
- T. Y. LING
- T. YETKIN
- T. ZIMMERMAN
- T.H. MÜLLER
- TRAVAGLINI RICCARDO
- U. AHMAD
- U. AKGUN
- U. BEHRENS
- U. BERTHON
- U. BERZANO
- U. CAZZOLA
- U. DOSSELLI
- U. FELZMANN
- U. GASPARINI
- U. GASTALDI
- U. GOERLACH
- U. HOLM
- U. HORISBERGER
- U. JOSHI
- U. LANGENEGGER
- U. NAUENBERG
- U. PEIN
- U. RÖSER
- V. ABRAMOV
- V. ALEKSANDROV
- V. ANDREEV
- V. B. FRANCIS
- V. BARASHKO
- V. BHANDARI
- V. BHATNAGAR
- V. BOYER
- V. BRIGLJEVIC
- V. CHEKHOVSKY
- V. CHIOCHIA
- V. CHOROWICZ
- V. CIULLI
- V. CUPLOV
- V. D. CAFARO
- V. D. ELVIRA
- V. DELACHENAL
- V. DUK
- V. E. BARNES
- V. E. BAZTERRA
- V. E. POSTOEV
- V. ELSHA
- V. EPSHTEYN
- V. GAULTNEY
- V. GAVRILOV
- V. GENCHEV
- V. GIORDANO
- V. GOLOVTSOV
- V. GRISHIN
- V. HAGOPIAN
- V. HALYO
- V. HERMEL
- V. ILYIN
- V. INNOCENTE
- V. ISSAKOV
- V. J. SMITH
- V. KACHANOV
- V. KAFTANOV
- V. KALAGIN
- V. KARIMÄKI
- V. KARJAVIN
- V. KARPISHIN
- V. KASEY
- V. KHABAROV
- V. KHACHATRYAN
- V. KHOMENKOV
- V. KIM
- V. KLYUKHIN
- V. KOLOSOV
- V. KONOPLYANIKOV
- V. KORENKOV
- V. KOZHUHAROV
- V. KOZLOV
- V. KOZLOV
- V. KRUTELYOV
- V. KRYCHKINE
- V. KUDINOV
- V. KUZNETSOV
- V. LEBEDEV
- V. LEFÉBURE
- V. LEMAITRE
- V. LITVINE
- V. LUKANIN
- V. LUKYANOV
- V. LYSIAKOV
- V. LYUBYNSKIY
- V. M. GHETE
- V. MACK
- V. MAKARENKO
- V. MAROUSSOV
- V. MATVEEV
- V. MICCIO
- V. MIKHAYLIN
- V. MOLCHANOV
- V. MONACO
- V. MOSSOLOV
- V. OGURI
- V. O’DELL
- V. PALICHIK
- V. PATRAS
- V. PAVLUNIN
- V. PERELYGIN
- V. PETROV
- V. PETROV
- V. PETUKHOV
- V. PIKALOV
- V. PODRASKY
- V. POSTOLACHE
- V. PROSOLOVICH
- V. R. LAKKIREDDI
- V. RADICCI
- V. ROBERFROID
- V. ROINISHVILI
- V. RYJOV
- V. SAKHAROV
- V. SAMSONOV
- V. SAVRIN
- V. SEHGAL
- V. SEKHRI
- V. SENCHYSHYN
- V. SHARMA
- V. SHELIKHOV
- V. SKNAR
- V. SKOROBOGATOV
- V. SKVORTSOV
- V. SMETANNIKOV
- V. SMIRNOV
- V. SPASSOV
- V. STOLIN
- V. SULIMOV
- V. SUNDARARAJAN
- V. SYTNIK
- V. TALOV
- V. TANCINI
- V. TARAKANOV
- V. TIMCIUC
- V. V. MITSYN
- V. VALUEV
- V. VANIEV
- V. VERGUILOV
- V. YARBA
- V. ZAYTSEV
- V. ZHUKOV
- V. ZHUKOVA
- VERONESE GIULIO PAOLO
- W. ADAM
- W. AHMED
- W. BADGETT
- W. BEAUMONT
- W. BERTL
- W. BIALAS
- W. BRAUNSCHWEIG
- W. BUSZA
- W. CAMERON
- W. D. SCHLATTER
- W. D. ZEUNER
- W. DAGENHART
- W. DE BOER
- W. DOMINIK
- W. DULINSKI
- W. E. KAHL
- W. ERDMANN
- W. FUNK
- W. G. D. DHARMARATNA
- W. GANNON
- W. GEIST
- W. GLESSING
- W. GORN
- W. H. SMITH
- W. H. THÜMMEL
- W. HINTZ
- W. J. GILBERT
- W. J. HAYNES
- W. J. SPALDING
- W. J. WOMERSLEY
- W. JANK
- W. JOHNS
- W. KARPINSKI
- W. KASTLI
- W. KO
- W. LI
- W. LIN
- W. LUSTERMANN
- W. M. WU
- W. M. ZABOLOTNY
- W. R. ZHAO
- W. REUTER
- W. SAKUMOTO
- W. SOBEK
- W. SUN
- W. T. FORD
- W. TANENBAUM
- W. TOMME
- W. VAN DONINCK
- W. WALTENBERGER
- W. ZABOLOTNY
- X. ASLANOGLOU
- X. LAGRUE
- X. QU
- X. ROUBY
- X. SU
- X. T. HUANG
- X. Y. SHEN
- X. YANG
- Y. B. HSIUNG
- Y. BAGATURIA
- Y. BAN
- Y. BONUSHKIN
- Y. C. GE
- Y. CHAO
- Y. E. KIM
- Y. ERSHOV
- Y. FISYAK
- Y. FU
- Y. GAVRIKOV
- Y. GEEREBAERT
- Y. GERSHTEIN
- Y. GOTRA
- Y. GUO
- Y. H. CHANG
- Y. HU
- Y. I. CHOI
- Y. IVANOV
- Y. J. KIM
- Y. J. LEI
- Y. K. JENG
- Y. KIRYUSHIN
- Y. KOZHEVNIKOV
- Y. KUBOTA
- Y. L. YE
- Y. LEMOIGNE
- Y. M. TZENG
- Y. MA
- Y. MARAVIN
- Y. MEL’NIK
- Y. MUSIENKO
- Y. N. KOBLIK
- Y. ONEL
- Y. PAKHOTIN
- Y. PISCHALNIKOV
- Y. RIAHI
- Y. ROH
- Y. S. CHUNG
- Y. S. SHAH
- Y. SHCHEGLOV
- Y. SHI
- Y. SIROIS
- Y. VELIKZHANIN
- Y. W. BAEK
- Y. WU
- Y. XIA
- Y. YANG
- Y. ZHANG
- Y. ZHENG
- Y.U. ANDREEV
- Z. AFTAB
- Z. ANTUNOVIC
- Z. C. YANG
- Z. CHEN
- Z. GAO
- Z. H. SUN
- Z. H. XUE
- Z. HOCHMAN
- Z. L. TROCSANYI
- Z. L. XUE
- Z. PRILUTSKAYA
- Z. SZABO
- Z. SZILLASI
- Z. TOTEVA
- Z. TSAMALAIDZE
- Z. WAN
- Z. WLODARCZYK
- Z. XIE
- Z. Y. CHEN
- Z. ZHANG
- Z. ZINONOS
- Publication venue
- INSTITUTE OF PHYSICS PUBLISHING (IOP)
- Publication date
- 01/01/1989
- Field of study
Peer reviewe
Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial
- Author
- Abab Julie
- Abbas Ali
- Abbassi Sara
- Abd Alazeez Mohamed
- Abdulwahid Danya
- Abdulwahid Danya
- Abed Jessy
- Adab Fawzi
- Adams Marion
- Adamson Vanessa
- Addison Anglise
- Adeyoju Adebanji
- Adinkra Victoria
- Adnaan Jamila
- Afzal Naveed
- Agdiran Didem
- Aggarwal Ajay
- Ahamadali Sheefa
- Ahmad Belal
- Ahmed Ilyas
- Ahmed Imtiaz
- Ahmed Shahida
- Aiku Abimbola
- Ainsworth Sarah
- Ainsworth Sarah
- Aitken Katherine
- Ajzensztejn Daniel
- Akhtar Naeem
- Al-Chamali Hiba
- Al-hasso Abdulla
- Al-hasso Abdulla
- Al-Samarraie Amir
- Albrecht Virginia
- Alcock Christopher
- Alder Leanne
- Alderton Kate
- Aldous Mary
- Ali Jennyfa
- Ali Maryam
- Ali Zulfiqer
- Ali Zulfiqer
- Allan Elaine
- Allan Elaine
- Allen Julie
- Allen Kirsten
- Allen Rachael
- Allen Susan
- Allison Joanna
- Allison Michele
- Alonzi Roberto
- AlRashdan Abdulla
- Alzouebi Mymoona
- Amanie John Oliver
- Ammeter Barb
- Amoaten Thomas
- Amos Claire
- Anderson Beverley
- Anderson Chris
- Anderson Jim
- Anderson John
- Anderson John
- Anderson Juliette
- Anderson Juliette
- Anderson Leanne
- Anderson Naomi
- Anderson Susan
- Anderson Susan
- Andrade Gerard
- Andrews (nee Moore) Eleanor
- Andrews Kelly
- Andrews Stephen
- Ang Daniel
- Ann Taehee
- Annan Lynda
- Ansari Jawaher
- Ansari Jawaher
- Anscombe Eleanor
- Anyamene Nicola
- Appleby Bonny
- Appleby Rowan
- Archer Denise
- Archer Denise
- Archer Simon
- Archer Simon
- Arnott Seonaid
- Arsanious Nasr
- Ashcroft Jan
- Ashworth Sue
- Ashworth Sue
- Askew Sarah
- Aslam Natasha
- Atkinson Jane
- Atkinson Lorraine
- Attlee Julie
- Auladin Raidah
- Austin (nee Glover) Gemma
- Austin Mandy
- Avery Alison
- Avis Joanne
- Aya Viviana
- Azirar Hanna
- Bachand Francois
- Bahary JeanPaul
- Bahl Amit
- Bahl Amit
- Bailey Laura
- Bailey Linda
- Baines Kizzy
- Baird Noelle
- Bak Dagmara
- Bakawala Rehana
- Baker Erin
- Baker Ivanna
- Bakija Zeljka
- Bakker Piet
- Balderson Jane
- Ball Julie
- Balogun Shaki
- Bamford Linda
- Banda Laillah-Crystal
- Barber Dave
- Baria Karin
- Barkati Maroie
- Barkati Maroie
- Barke Nyssa
- Barlow David
- Barnbrooke Sarah
- Barnes Alison
- Barnes Nicky
- Barnett Christian
- Barnett Debra
- Barron Chris
- Barron Claire
- Barter Elisa
- Barwell Lorraine
- Bashir Bashir
- Bashir Faheem
- Basu Devy
- Bateman Samantha
- Bates Emma
- Batish Cheryl
- Batz Margaret
- Bauman Glenn
- Baumber Shelley
- Baxter Matt
- Bayley Andrew J
- Beamish Neal
- Beaney Katherine
- Beaney Ronald
- Beard Karen
- Beard Karen
- Beaton Heather
- Beaton Kirsty
- Beattie Louise
- Beauchemin MarieClaude
- Beaumont Erica
- Beausoleil Rachelle
- Beazer Sarah
- Bech-Nielsen Nanette
- Bech-Nielsen Nanette
- Bedoya Luis Diaz de
- Beech Darren
- Beer Nigel
- Beesley Kate
- Beesley Katherine
- Beesley Sharon
- Beety Jane
- Bekulart Sylwia
- Belcher Rebecca
- Bell Karen
- Bellenger Katharine
- Benjaminson Patricia
- Bennett Molly
- Bennett Sarah
- Bennion Carole
- Benson Richard
- Benson Richard
- Benth Silvine
- Benton Louise
- Benton Richard
- Bentzen Lise
- Beresford Mark
- Beresford Mark
- Beresford Mark
- Bergen Leah
- Berghout Koralee
- Berlin Alejandro
- Bermingham Nicola
- Betts Chris
- Bhana Rajanee
- Bhatnagar Adityanarayan
- Bhatnagar Gagan
- Bici Julia
- Bier Bianca
- Binks Colin
- Binns Louise
- Birch Richard
- Bird Stephanie
- Birtle Alison
- Bishop Emma
- Bissa Caterina
- Bissett Donald
- Bisson MarieEve
- Blackwood Geoffrey
- Blaney Hilary
- Blight Kathy
- Blood Paul A
- Bloomfield David
- Bloomfield David
- Bloomfield Mark
- Blundell Martyn
- Blythe Tracy
- Boam Samantha
- Boardman John
- Bohra Vikram
- Bois (nee Harris) Elizabeth
- Bolger Annette
- Bolton Olivia
- Bolton Olivia
- Bond Brittany
- Bone Linzi
- Bonner Scott
- Bonner-Shand Shelagh
- Bonsu Nicole
- Boon Ian
- Borgaonkar Sudhir
- Borre Michael
- Borynec Carol
- Bott Trevor
- Bottomley David
- Bottomley David
- Bottomley David M.
- Bottomley Ian
- Bouchard Myriam
- Bourke Amie
- Bourque JeanMarc
- Boutflower Jane
- Bowen Jo
- Bowen Jo
- Bowen Katie
- Bower Lorna
- Bower Lorna C.
- Bowers Dawn
- Bowers Richard
- Bowes-Cavanagh Jeanette
- Bowling Lorna
- Bowman Sue
- Bowmer Amanda
- Bownie-Mukumbu Godfrey
- Brady Joanne
- Brady Joanne
- Brain Carol
- Branagan Jennifer
- Branagan Jenny
- Brander Mike
- Branson (née Dineen) Amy
- Brasso Klaus
- Braun Michael W
- Brawley Chris
- Breakspear Sally
- Breckin Edmund
- Breen Vivienne
- Brennan Maria
- Brewster Simon
- Briand Wayne
- Briggs Maxine
- Bristow Robert
- Brittain Paul
- Broadley Eve
- Brock Sue
- Brock Sue
- Brogan (nee Roddie) Stephanie
- Brookes Claire
- Brookman Catherine
- Broom Jane
- Broomfield Barbara
- Brough Richard
- Brough Richard
- Brough WA
- Brown Emmanuel
- Brown Grace
- Brown Joanne
- Brown Maggie
- Brown Rebecca
- Brown Richard B
- Brown Richard B
- Brown Sandra
- Brown Simon
- Brown Stephen CW
- Brown Teddy
- Brownless Caroline
- BrucePayne Kim
- Brulinski Patryk
- Brulinski Patryk
- Brundage Michael
- Bryan Rachel
- Bryant Hanna
- Brydon-Hill Ruth
- Bucci Catherine
- Buchan Jonathan
- Buckley Jon
- Buckley Julie
- Bujold Rachel
- Bunn Sarah
- Burbridge Susan
- Burgoyne Jamie-Rae
- Burlace Barbara
- Burlace Barbara
- Burns Rebecca
- Burrage Su
- Bursey Kara
- Butler-Barnes Jenny
- Butt Zainab
- Butterfield Anne
- Butterworth Caryl
- Buus Simon
- Byrne Mary Marg
- Caballes Mark
- Cadiz Lovely
- Callam Sara
- Calvert Clare
- Camara Mary Jane
- Camburn Sister Tracey
- Camilleri Philip
- Camilleri Philip
- Camilleri Philip
- Camilleri Philip
- Campbell Allister
- Campbell Audrey
- Campbell Hilary
- Campbell Yvonne
- Campos Monica
- Canavan Joycelin
- Cannon Philip
- Capaldi Lisa
- Capaldi Lisa
- Capaldi Lisa
- Carbonaro Adriana
- Carefoot Layton
- Carini Serrafina
- Carkner Amy
- Carlino Giulia
- Carlson Cindy
- Carmel Michel
- Carpenter Janice
- Carpenter Janice
- Carpio Viviana
- Carr Philippa
- Carroll Weronika
- Carruthers Ross
- Carter Adam
- Carter Vanda
- Cartwright Debbie
- Carvery Lane
- Casanova Nathalie
- Casanova Nathalie
- Casey Linda
- Casey Sue
- Catt Natalie
- Catton Charles
- Catton Charles N.
- Caumont Tom
- Cavanagh Kerrie
- Chadwick David
- Chadwick Eliot
- Chahal Rohit
- Chahine Jacqueline
- Chakraborti Prabir
- Challipalli Amarnath
- Challipalli Amarnath
- Chamberlain Shelley
- Chambers Carla
- Chan Andrew
- Chan Andrew
- Chan Heidi
- Chan Hin Fan
- Chan Olivia
- Chandrashekara Madhura
- Charnley Natalie
- Chatelain AnneMarie
- Chatfield Jenny
- Chauhan Zainab
- Chedham Alison
- Chennattukungu Indukala
- Cherepak Kathy
- Chetiyawardana Samantha
- Chetiyawardana Samantha
- Chettle Judith
- Cheung Arthur
- Cheung Patrick CF
- Chikkamuniyappa Bindu
- Chikkamuniyappa Bindu
- Chikopela Loveness
- Chilcott Helen
- Chipman Penny
- Chivers Rachael
- Chornopyski Tracy
- Choudhury Ananya
- Choudhury Ananya
- Choudhury Ananya
- Chowdhury Amitava D
- Christensen Anne Juel
- Christensen Tine
- Christmas Sallyanne
- Chrystal Melanie
- Chu William
- Chui Amadeus
- Chung Christina
- Chung Hans T
- Chung Peter
- Chung Peter W.M.
- Churn Mark
- Churn Mark
- Clancy Joanna
- Clapp Felicity
- Clark Alison
- Clark Diane
- Clark Helen
- Clark Katy
- Clark Su
- Clarke Elizabeth
- Clarke Jude
- Clarke Maria
- Clarke Noel
- Clarke Noel W.
- Clarke Peter
- Clarke Rachael
- Clarke Samantha
- Cleary Kristy
- Clements Colette
- Clements Mia AnnaMaria
- Clitheroe Pat
- Cobos-Arrivabene Marta
- Cocks Tracie
- Coe Marc
- Coffin Teresa
- Cogley Lyn
- Cogley Lyn
- Cole Aiden
- Cole David J
- Cole David J
- Collard Susan
- Colligan Steve
- Collins Gerald
- Collins Gerald
- Collins Lucy
- Commisso Angela
- Conibear John
- Connolly nee McKenna Sarah
- Connor Marie
- Conroy Ruth
- Conroy Ruth
- Conway Lisa-Jane
- Conway Rachel
- Cook Adrian
- Cook Adrian D.
- Cook Audrey
- Cook Audrey
- Cook Wendy
- Cooke Jill
- Cooke Juniebel
- Cooke Peter
- Coomber Kristy
- Coombs Sarah
- Cooper Adele
- Cooper Sophie
- Coppins Helen
- Corbett Thomas B
- Corcoran Sam
- Corderoy Helen
- Cordwell Amanda
- Corkery Danylle
- Corless Rebecca
- Cormack Margaret
- Cornaby Andrew
- Corner Victoria
- Cornthwaite Stephanie
- Corwin Charlotte
- Cossette Danielle
- Cote Genevieve
- Cotterill Lauren
- Cotts Shannon
- Coubrough Claudia
- Couch Ellie
- Coughlan Tricia
- Cousins Jane
- Cousins Rebecca
- Coutts Tim
- Coventry Thomas
- Cowan Chloe
- Cowan Chloe
- Cowan Richard
- Cowan Richard
- Cowley Sue
- Cox Adam
- Cox Christine
- Coyle Catherine
- Coyle Catherine
- Crawford Melanie
- Crawford Sister Denise
- Creelman Brianna
- Crellin Perric
- Crellin Perric
- Crook Juanita
- Cross Vanessa
- Cross William R.
- Crossley Lin
- Crowe (nee Hughes) Dawn
- Crowley Claire
- Crundwell M
- Cserbane Anita
- Cuffe Donna
- Cumming Kirsty
- Cunningham Amy
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- Curtis Sandra
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- Dawe David
- Dawson Elizabeth
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- Dawson-Athey Linda
- Dayes Ian S
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- Dean Lynsey
- Dearnaley David
- Deenihan Emma
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- Downs Nichola
- Doyle Kerrie
- Drachenberg Darrel E
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- Dubey Arbind
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- E Choan
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- Gauntlett Monica
- Gauthier Isabelle C
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- Glaholm John
- Glaholm John
- Gleave Martin E
- Glen Hilary
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- Golden Sophie
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- Goldstein Cindy
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- Goldsworthy Simon
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- Gonzalez Celia
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- Griffen Ailsa
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- Griffiths Theresa
- Gruschy Lisa
- Guarino Robyn
- Gudelis Susan O
- Guerrero-Urbano Teresa
- Guerrero-Urbano Teresa
- Guerrero-Urbano Teresa
- Gujral Sandeep
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- Hammonds John Christopher
- Hanna Emma
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- Harding Joshua
- Hardman John
- Hardstaff Lisa
- Hare Jennifer A
- Hargreaves Carolyn
- Hargreaves Jeanette
- Hargreaves Jeanette
- Harinarayanan Sathish
- Harinarayanan Sathish
- Harland Keith
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- Harris (n. Marchant) Emily
- Harris Catherine
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- Haskell Annelise
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- Hassan Nebah
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- Haydock Helen
- Haydock Helen
- Hayes Jill A
- Hayward Lesley
- Healey Gail
- Healey-Mariano Jennifer
- Healey-Mariano Jennifer
- Heasley Karen
- Heath Catherine
- Heckford Louise
- Hedges Andy
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- Hefferon Billy
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- Henry Ann
- Henry Ann
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- Henry Ann
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- Henry Joanne
- Henson (nee Savidge) Verity
- Henson Helen
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- Hijab Adham
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- Hillman Paul
- Hillman Paul
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- Hindle Margaret
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- Hocking Christopher
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- Hughes Owen
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- Hugill Angela
- Hugill Angela
- Humber Caroline
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- Hunter William
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- Hyde Katherine
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- Hynds Sharon
- Ibrahim Azman
- Ingham Jo
- Ingle Charlotte
- Inman Hayley
- Innes Helen
- Iordanidi Elina
- Iqbal Fawaad
- Irwin P
- Isaew Andrea
- Iskender Amanda
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- Jackman Dee
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- Jain Suneil
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- Jarvis Claire
- Jastrzebska Patrycja
- Javle P
- Jayachandran Resmi
- Jayachandran Resmi
- Jeffcutt Nicole
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- Jelski Joseph
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- Jenkins Suzanne
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- Jepson Debbie
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- Jewers Karen
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- Joe Howard
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- Jones Richard
- Jones Rob
- Jones Stephanie
- Jones Stephanie
- Jones-Skipper Kay
- Jonnada Sai
- Jope Carmel
- Jose Sanal
- Joseph Joji
- Joseph Paul K
- Joshi Manisha
- Joshi Manisha
- Joslin Vicky
- Jovic Gordana
- Kaa Bach Birgit
- Kader Nicole
- Kalejaiye Odunayo
- Kaliski Alexandre
- Kalyvas Maria
- Kamran Asim
- Kanaga-Sundaram Subramanian
- Kancherla Kiran
- Kanji Femina
- Kanyi Karen
- Kapur Guarav
- Karim Omer
- Karp Stephen
- Karsera Louise
- Karunakaran Subashini
- Karvat Anand
- Kaushal Malan
- Kavanagh Roisin
- Kavanagh Roisin
- Kay Anne Marie
- Kazingizi Memory
- Keane Patrick
- Kearney S
- Kedge Liz
- Kehoe Laura
- Keith Sarah
- Keith Sarah
- Kelkar Anand
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- Kelly Alison
- Kelly Kay
- Kemp Gail
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- Kendal Wayne S
- Keng-Koh Pek
- Keng-Koh Pek
- Keni Manjusha
- Kennedy Julie
- Kenny Shannon
- Kent Christopher
- Kent Emma
- Kenyon Lucille
- Kershaw Elizabeth
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- Keyes Mira
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- Khoo Vincent
- Khoury Ghassan
- Kiff Janet
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- Kilmartin John
- Kilroy Stephen
- Kilroy Stephen
- Kiltie Anne
- Kiltie Anne
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- King Amy
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- Kirkbride Peter
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- Kirkpatrick Suriya
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- Klapp Kathi
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- Knackstedt Jochen
- Knapp Jeanette
- Knight (n. Sherburn) Victoria
- Knott Helen
- Knox WF
- Kockelbergh Roger
- Koehler Ingrid
- Kokholm Kathrine Friser
- Koll Wayne
- Kong Vickie
- Kotze Michelle
- Koul Rashmi
- Koulouris Zoe
- Koupparis Anthony
- Kowalczyk-Williams Wioletta
- Kowalewska Paulina
- Kronstal Flo
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- Kuenzig Greg
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- Kurup Rahul
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- Laing Robert
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- Lake Sister Judith
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- Lambert Carole
- Lambert Katy
- Lamoureux Alexandra
- Lang Monika
- Langridge Nicole
- Laniado M
- Lao Bernadeth
- Larkins Rachel
- Larocque Stephanie
- Larouche Julie
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- Lau Maurice
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- Lewis Amanda
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- Littler John
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- Liu Stanley
- Livsey Jacqueline
- Livsey Jacqueline
- Lloyd-Jones Hugh
- Loblaw Douglas Andrew
- Lock Michael I
- Locke Angela
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- Logue John
- Logue John
- Logue John
- Logue John
- Lokes Rachel
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- Lomas Alia
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- Love Sally
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- Lydon Anna
- Lydon Anne Marie
- Lynch Rory
- Lyons Ciara
- Mabelin Louies
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- Macdonald Alison
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- MacDonald Graham
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- MacGregor Barbara
- Macgregor Carol
- MacIsaac Kathy
- MacIsaac Patricia
- Mackay Rachel
- Macleod Nicholas
- MacMillan Antonia
- MacMullin Lisa
- MacRae Robert M
- Macrory Joanne
- MacVicar Jennifer
- MacVicar Karen
- Madeleine Jude
- Madhava Kudingila
- Madine John
- Magwaro Sophia
- Magwaro Sophia
- Magwaro Sophia
- Mahmood Rana
- Mahmood Rana
- Mahmood Sana
- Mahmud Aamer
- Mahoney Catriona
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- Maitland Katrina
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- Makepeace Barbara
- Malde Rohit
- Malek Leila
- Malik Zafar
- Mallett Debbie
- Malone Shawn
- Malone Shawn C.
- Manetta Caroline
- Manganaro Aileen
- Mangar Stephen
- Maniatis Christos
- Manley Rachel
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- Mantle Mark
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- Mardell Stephen
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- Mashegede Beverley
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- Masson Susan
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- Masters Lindsey
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- McClements Jane
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- McCormack Anne
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- McCracken Jillian
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- McFarlane Jonathan
- McFarlane Victoria
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- McGlynn Brian
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- McKee Dianne
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- McKinna Fiona
- McLain-Smith Susan
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- Mcleod Nick
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- Melcher Lucinda
- Melcher Lucinda
- Menard Cynthia
- Menard Cynthia
- Mendoza Edeliza
- Merante Pat
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- Merrick Richard
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- Meyer Ralph
- Michael Elena
- Michaelidou Andriana
- Michels Jorg
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- Mikropoulos Christos
- Millage Helen
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- Mills Laurie
- Mills-Baldock Tina
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- Milosevic Michael
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- Mohamed Fatima
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- Mole Lisa
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- Money-Kyrle Julian
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- Moore Eleanor
- Moore Eleanor
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- Morgan Rachel
- Morgan Scott
- Morris Stephen
- Morris Stephen L.
- Morris William James
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- Morrison MaryBeth
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- Mthethwa Thobekile
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- Musunuru Hima Bindu
- Muthukumar Dakshinamoorthy
- Myatt Alison
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- Nabid Abdenour
- Nabid Abdenour
- Nagar Yoodhvir
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- Nakashima Lynne
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- Nathan Kannon
- Nawrozzadeh Mohammed
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- Ngumo Alice
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- Nicholson Alastair
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- Ong Aldrich D.
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- Page Nancy
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- Paisey Sangeeta
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- Panades Miguel
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- Zarkar Anjali
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- Zelley Sarah
- Zeltser Fred
- Zhang Hanbo
- Zhang Tina Wanting
- Zietz Maria
- Zilkha Helene
- Zinck Connie
- Zinyemba Vivian
- Zurakovsky Hilary
- Zwarych Darlene
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/06/2024
- Field of study
Background
Previous evidence indicates that adjuvant, short-course androgen deprivation therapy (ADT) improves metastasis-free survival when given with primary radiotherapy for intermediate-risk and high-risk localised prostate cancer. However, the value of ADT with postoperative radiotherapy after radical prostatectomy is unclear.
Methods
RADICALS-HD was an international randomised controlled trial to test the efficacy of ADT used in combination with postoperative radiotherapy for prostate cancer. Key eligibility criteria were indication for radiotherapy after radical prostatectomy for prostate cancer, prostate-specific antigen less than 5 ng/mL, absence of metastatic disease, and written consent. Participants were randomly assigned (1:1) to radiotherapy alone (no ADT) or radiotherapy with 6 months of ADT (short-course ADT), using monthly subcutaneous gonadotropin-releasing hormone analogue injections, daily oral bicalutamide monotherapy 150 mg, or monthly subcutaneous degarelix. Randomisation was done centrally through minimisation with a random element, stratified by Gleason score, positive margins, radiotherapy timing, planned radiotherapy schedule, and planned type of ADT, in a computerised system. The allocated treatment was not masked. The primary outcome measure was metastasis-free survival, defined as distant metastasis arising from prostate cancer or death from any cause. Standard survival analysis methods were used, accounting for randomisation stratification factors. The trial had 80% power with two-sided α of 5% to detect an absolute increase in 10-year metastasis-free survival from 80% to 86% (hazard ratio [HR] 0·67). Analyses followed the intention-to-treat principle. The trial is registered with the ISRCTN registry, ISRCTN40814031, and ClinicalTrials.gov, NCT00541047.
Findings
Between Nov 22, 2007, and June 29, 2015, 1480 patients (median age 66 years [IQR 61–69]) were randomly assigned to receive no ADT (n=737) or short-course ADT (n=743) in addition to postoperative radiotherapy at 121 centres in Canada, Denmark, Ireland, and the UK. With a median follow-up of 9·0 years (IQR 7·1–10·1), metastasis-free survival events were reported for 268 participants (142 in the no ADT group and 126 in the short-course ADT group; HR 0·886 [95% CI 0·688–1·140], p=0·35). 10-year metastasis-free survival was 79·2% (95% CI 75·4–82·5) in the no ADT group and 80·4% (76·6–83·6) in the short-course ADT group. Toxicity of grade 3 or higher was reported for 121 (17%) of 737 participants in the no ADT group and 100 (14%) of 743 in the short-course ADT group (p=0·15), with no treatment-related deaths.
Interpretation
Metastatic disease is uncommon following postoperative bed radiotherapy after radical prostatectomy. Adding 6 months of ADT to this radiotherapy did not improve metastasis-free survival compared with no ADT. These findings do not support the use of short-course ADT with postoperative radiotherapy in this patient population
Duration of androgen deprivation therapy with postoperative radiotherapy for prostate cancer: a comparison of long-course versus short-course androgen deprivation therapy in the RADICALS-HD randomised trial
- Author
- Abab Julie
- Abbas Ali
- Abbassi Sara
- Abd Alazeez Mohamed
- Abdulwahid Danya
- Abdulwahid Danya
- Abed Jessy
- Adab Fawzi
- Adams Marion
- Adamson Vanessa
- Addison Anglise
- Adeyoju Adebanji
- Adinkra Victoria
- Adnaan Jamila
- Afzal Naveed
- Agdiran Didem
- Aggarwal Ajay
- Ahamadali Sheefa
- Ahmad Belal
- Ahmed Ilyas
- Ahmed Imtiaz
- Ahmed Shahida
- Aiku Abimbola
- Ainsworth Sarah
- Ainsworth Sarah
- Aitken Katherine
- Ajzensztejn Daniel
- Akhtar Naeem
- Al-Chamali Hiba
- Al-hasso Abdulla
- Al-hasso Abdulla
- Al-Samarraie Amir
- Albrecht Virginia
- Alcock Christopher
- Alder Leanne
- Alderton Kate
- Aldous Mary
- Ali Jennyfa
- Ali Maryam
- Ali Zulfiqer
- Ali Zulfiqer
- Allan Elaine
- Allan Elaine
- Allen Julie
- Allen Kirsten
- Allen Rachael
- Allen Susan
- Allison Joanna
- Allison Michele
- Alonzi Roberto
- AlRashdan Abdulla
- Alzouebi Mymoona
- Amanie John Oliver
- Ammeter Barb
- Amoaten Thomas
- Amos Claire
- Anderson Beverley
- Anderson Chris
- Anderson Jim
- Anderson John
- Anderson John
- Anderson Juliette
- Anderson Leanne
- Anderson Naomi
- Anderson Susan
- Anderson Susan
- Andrade Gerard
- Andrews (nee Moore) Eleanor
- Andrews Kelly
- Andrews Stephen
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- Ansari Jawaher
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- Anyamene Nicola
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- Bowmer Amanda
- Bownie-Mukumbu Godfrey
- Brady Joanne
- Brady Joanne
- Brain Carol
- Branagan Jenny
- Brander Mike
- Branson (née Dineen) Amy
- Brasso Klaus
- Brasso Klaus
- Braun Michael W
- Brawley Chris
- Brawley Chris
- Breakspear Sally
- Breckin Edmund
- Breen Vivienne
- Brennan Maria
- Brewster Simon
- Briand Wayne
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- Bristow Robert
- Brittain Paul
- Broadley Eve
- Brock Sue
- Brock Sue
- Brogan (nee Roddie) Stephanie
- Brookes Claire
- Brookman Catherine
- Broom Jane
- Broomfield Barbara
- Brough Richard
- Brough Richard
- Brough WA
- Brown Emmanuel
- Brown Grace
- Brown Joanne
- Brown Maggie
- Brown Rebecca
- Brown Richard B
- Brown Richard B
- Brown Sandra
- Brown Simon
- Brown Stephen CW
- Brown Teddy
- Brownless Caroline
- BrucePayne Kim
- Brulinski Patryk
- Brulinski Patryk
- Brundage Michael
- Bryan Rachel
- Bryant Hanna
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- Bucci Catherine
- Buchan Jonathan
- Buckley Jon
- Buckley Julie
- Bujold Rachel
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- Burlace Barbara
- Burlace Barbara
- Burns Rebecca
- Burrage Su
- Bursey Kara
- Butler-Barnes Jenny
- Butt Zainab
- Butterfield Anne
- Butterworth Caryl
- Buus Simon
- Byrne Mary Marg
- Caballes Mark
- Cadiz Lovely
- Callam Sara
- Calvert Clare
- Camara Mary Jane
- Camburn Sister Tracey
- Camilleri Philip
- Camilleri Philip
- Camilleri Philip
- Camilleri Philip
- Campbell Allister
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- Campbell Yvonne
- Campos Monica
- Canavan Joycelin
- Cannon Philip
- Capaldi Lisa
- Capaldi Lisa
- Capaldi Lisa
- Carbonaro Adriana
- Carefoot Layton
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- Carmel Michel
- Carpenter Janice
- Carpenter Janice
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- Carter Adam
- Carter Vanda
- Cartwright Debbie
- Carvery Lane
- Casanova Nathalie
- Casanova Nathalie
- Casey Linda
- Casey Sue
- Catt Natalie
- Catton Charles
- Catton Charles N
- Caumont Tom
- Cavanagh Kerrie
- Chadwick David
- Chadwick Eliot
- Chahal Rohit
- Chahine Jacqueline
- Chakraborti Prabir
- Challipalli Amarnath
- Challipalli Amarnath
- Chamberlain Shelley
- Chambers Carla
- Chan Andrew
- Chan Andrew
- Chan Heidi
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- Chan Olivia
- Chandrashekara Madhura
- Charnley Natalie
- Chatelain AnneMarie
- Chatfield Jenny
- Chauhan Zainab
- Chedham Alison
- Chennattukungu Indukala
- Cherepak Kathy
- Chetiyawardana Samantha
- Chetiyawardana Samantha
- Chettle Judith
- Cheung Arthur
- Cheung Patrick CF
- Chikkamuniyappa Bindu
- Chikkamuniyappa Bindu
- Chikopela Loveness
- Chilcott Helen
- Chipman Penny
- Chivers Rachael
- Chornopyski Tracy
- Choudhury Ananya
- Choudhury Ananya
- Chowdhury Amitava D
- Christensen Anne Juel
- Christensen Tine
- Christmas Sallyanne
- Chrystal Melanie
- Chu William
- Chui Amadeus
- Chung Christina
- Chung Hans T
- Chung Hans T
- Chung Peter
- Chung Peter W M
- Churn Mark
- Churn Mark
- Clancy Joanna
- Clapp Felicity
- Clark Alison
- Clark Diane
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- Clark Katy
- Clark Su
- Clarke Elizabeth
- Clarke Jude
- Clarke Maria
- Clarke Noel
- Clarke Noel W
- Clarke Peter
- Clarke Rachael
- Clarke Samantha
- Cleary Kristy
- Clements Colette
- Clements Mia AnnaMaria
- Clitheroe Pat
- Cobos-Arrivabene Marta
- Cocks Tracie
- Coe Marc
- Coffin Teresa
- Cogley Lyn
- Cole Aiden
- Cole David J
- Cole David J
- Collard Susan
- Colligan Steve
- Collins Gerald
- Collins Gerald
- Collins Lucy
- Commisso Angela
- Conibear John
- Connolly nee McKenna Sarah
- Connor Marie
- Conroy Ruth
- Conroy Ruth
- Conroy Ruth
- Conway Lisa-Jane
- Conway Rachel
- Cook Adrian
- Cook Adrian D
- Cook Audrey
- Cook Audrey
- Cook Wendy
- Cooke Jill
- Cooke Juniebel
- Cooke Peter
- Coomber Kristy
- Coombs Sarah
- Cooper Adele
- Cooper Sophie
- Coppins Helen
- Corbett Thomas B
- Corcoran Sam
- Corderoy Helen
- Cordwell Amanda
- Corkery Danylle
- Corless Rebecca
- Cormack Margaret
- Cornaby Andrew
- Corner Victoria
- Cornthwaite Stephanie
- Corwin Charlotte
- Cossette Danielle
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- Coubrough Claudia
- Couch Ellie
- Coughlan Tricia
- Cousins Jane
- Cousins Rebecca
- Coutts Tim
- Coventry Thomas
- Cowan Chloe
- Cowan Chloe
- Cowan Richard
- Cowan Richard
- Cowley Sue
- Cox Adam
- Cox Christine
- Coyle Catherine
- Coyle Catherine
- Crawford Melanie
- Crawford Sister Denise
- Creelman Brianna
- Crellin Perric
- Crellin Perric
- Crook Juanita
- Cross Vanessa
- Cross William R
- Crossley Lin
- Crowe (nee Hughes) Dawn
- Crowley Claire
- Crundwell M
- Cserbane Anita
- Cuffe Donna
- Cumming Kirsty
- Cunningham Amy
- Curtis Samantha
- Curtis Sandra
- Cusan Leonello
- Custins Laura
- Cyriac Abby
- Dabbs Marianne
- Dahar Nazeer
- Dahmane Rafika
- Dallas Nicola
- Dalton-Short Ross
- Dalton-Short Ross
- Daly Deirdre
- Danaswamy Patricia
- Danaswamy Patricia
- Daniel Amelia
- Danielson Brita
- Danjoux Cyril
- Darby Helen
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- Das Prantik
- Davda Reena
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- Davey Elizabeth
- Davidson Cathy
- Davies Emily
- Davies Flor
- Davies Heather
- Davies Joe
- Davies Joseph
- Davies Julie-Ann
- Davies Kirstin
- Davies Llinos
- Davies Stacey
- Davies Sue
- Davies Tracey
- Davison Alison
- Davison Sue
- Dawe David
- Dawson Elizabeth
- Dawson Louise
- Dawson-Athey Linda
- Dayes Ian S
- De Silva-Minor Shiroma
- Dean Lynsey
- Dearnaley David
- Deenihan Emma
- Degendorfer Sarah
- Dekaj Fatjon
- Dell Gillian
- Dellar Conor
- Delouya Guila
- Dent Kathleen
- Desai Parth
- Desai Parth
- Desrosiers Isabelle
- Dewar Lorna
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- Di Maria Fabio
- Dias Heather
- Dickinson Peter
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- Din Omar
- Ding Ian
- Dion Helene
- Ditchfield Julie
- Dixit Sanjay
- Dixit Sanjay
- Dlodlo Jessica
- Dobson Tracey
- Dodds David
- Dodge Sister Jan
- Doherty A
- Donaghey Sally
- Donaldson David
- Donnison Michelle
- Douch Emma
- Doughty Victoria
- Dover Serena
- Downs Nichola
- Doyle Kerrie
- Drachenberg Darrel E
- Drakeley Susan
- Drew Ellen
- Drew Mary (Ellen)
- Driscoll Celine
- DSouza David
- Dubey Arbind
- Dubey Arbind
- Duckett Tracey
- Duclos Marie
- Duffy Annie
- Dufour Nathalie
- Dugas Stevie
- Duley Emma
- DuMontier Joelle
- Duncan (nee Keatley) Claire
- Duncan Graeme
- Duncan Ian
- Dunn Sharon
- Dunne Emma
- Durkan Garret
- Durrant Lisa
- Dymond Harvey
- E Choan
- Eady Robin
- Eapen Libni
- Ebacher Annie
- Eccleson Helen
- Edwards Abigail
- Edwards Albert
- Edwards Jackie
- Edwards Steve
- Edwards Steve
- Egan Lisa
- Eichenberger Lois
- El-Modir Ahmed
- El-Saghir Mohammed
- Eleftheriadis Symeon
- ElKerdawy Hala
- Ellard Rose
- Elliott Mark
- Elliott Tony
- Elliott Tony
- ElSokhn Nidale
- Elwell Christine
- Elwell Christine
- Elwell Sue
- Embleton Andrew
- Ennis Dawn
- Erskine Susan
- Escueta Vivette
- Eska Tiffani
- Etheridge Charlotte
- Evans Angela
- Evans Clary
- Evans Elizabeth
- Evans Marion
- Evans Melanie
- Evans Richard
- Eze Nancy
- Fair Kim
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- Falconer Alison
- Falconer Alison
- Fallah Fereshteh
- Fallaize Adrian
- Faria Sergio Luiz
- Farnworth Christine
- Farrar Michelle
- Farrell Helen
- Fawcitt Sara
- Fazekasne Fulep Adrienn
- Fearnley Mark
- Featherstone Wendy
- Fellows Kathryn
- Fennelly Ruth
- Ferguson Catherine
- Ferguson Catherine
- Fernandez Claire
- Ferreira Miguel
- Fiddes Kathleen
- Fielding Bethany
- Fielding Bethany
- Fildes Diane
- Finnegan Niall
- Firth Alexandra
- Firth Alexandra
- Firth Alexandra
- Firth Elizabeth
- Fish Matt
- Fish Nathan
- Flaherty Jan
- Flaherty Jan
- Flanagan Laura
- Flavin Aileen
- Fletcher Joanne
- Fletcher Julie
- Fletcher Mandy
- Flynn-Batham Marian
- Fode Kirsten
- Folkes Linda
- Follows Josh
- Foo Maxine
- Foot Jayne
- Forcat Silvia
- Ford Amanda
- Ford Amy
- Ford Chris
- Ford Daniel
- Ford Daniel
- Ford Nicky
- Ford Vicky
- Ford Victoria
- Ford Victoria
- Forkes Janet
- Forkes Janet
- Forkes Janet
- Forman Susan
- Forrest Diane
- Forrest Diane
- Fortin Jacqueline
- Fosker Chris
- Fossey Gavin
- Foster Emma
- Foster William
- Fourt Monica
- Fox Shirley
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- Francis Olesya
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- Frankland Helen
- Franklin Alex
- Frattaroli Paul
- Frazzi Alexandra
- Frew John
- Frim Olivera
- Froese Jane
- Froude Nancy
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- Galante Joao
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- Galloway Lucy
- Galway Denise
- Gamble Tina
- Gamble Tina
- Gamez Raquel
- Ganabady Malavika
- Gao Annie
- Garcia Leni Santiago
- Gardiner Fiona
- Garner Victoria
- Garrett Gina
- Garrido-Perez Sandra
- Gauntlett Monica
- Gauthier Isabelle C
- Gearing Jennifer
- George Siny
- GeorgeChayka Danielle
- Geraghty Kerry
- Ghoul Mokhtar
- Gibbins Andrew
- Gibbins Jackie
- Gibbins Kate
- Gibbs Stephanie
- Gibson Sian
- Giddings Emma
- Gilbert Duncan
- Gilbert Duncan
- Gilbert Jeanette
- Gilby Lisa
- Gilchrist Gail
- Gill Lisa
- Gill Shafiq
- Gillatt David
- Gillatt David
- Gillesen Annelies
- Gillespie Sally
- Gillian Andrew
- Gilmartin Claire
- Gilmour Christina
- Ginnelly Helen
- Ginnelly Helen
- Giovannini Julia
- Gipson Anna
- Girolametto Carla
- Gladwell Louise
- Gladwish Adam
- Glaholm John
- Glaholm John
- Gleave Martin E
- Glen Hilary
- Glen Tracy
- Glick Daniel
- Goel Roshni
- Goh Chee
- Goh Chee L
- Golden Sophie
- Goldenberg S Larry
- Goldstein Cindy
- Goldsworthy Simon
- Gollapothu Srilakshmi
- Gomez JoseLuis
- Gomez-Marcos Raquel
- Gonzalez Celia
- Gooch Carol
- Goodhind Frances
- Goodsell Josie
- Goodsell Josie
- Goodwin Emma
- Gopaul Darindra
- Gordon Hussain
- Gore Alexandra
- Gospodarowicz Mary
- Goss Vanessa
- Gough Jessica
- Gould Aaron
- Goulden Kay
- Goulding James
- Goyena Ruby
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- Graham Janet
- Graham Jeffrey
- Graham John
- Graham Susan
- Gramlich Colin
- Grant Anna
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- Grant Judith
- Grant Susan
- Grant Warren
- Gratton Albert
- Grau Isabel
- Gray Emma
- Gray Emma
- Grayland Sarah
- Greedus Helen
- Green James
- Green Sara
- Green Sarah
- Green Sue
- Green Trish
- Greenland Jonathan
- Gregg Jane
- Gregorcic Emily
- Gregory Debbie
- Grieve Sylvia
- Griffen Ailsa
- Griffin Hannah
- Griffiths Dorothy
- Griffiths Leyshon
- Griffiths Theresa
- Griffiths Theresa
- Gruschy Lisa
- Guarino Robyn
- Gudelis Susan O
- Guerrero-Urbano Teresa
- Guerrero-Urbano Teresa
- Guerrero-Urbano Teresa
- Gujral Sandeep
- Gumapac Nicole
- Gunn Melanie
- Gupta Kamalnayan
- Gupta Nishi
- Gurzanski Christina
- Guy Peter
- Gwilt Julie
- Gwilt Julie
- Gwilt Julie
- Haddad Alain
- Hagan Chris
- Hague Dominic
- Haidar Imran
- Haidar Imran
- Haigh Steve
- Haldeos Anne
- Hale Jennifer
- Hall Jane
- Hall Julia
- Hall Julia
- Halperin Ross
- Hamid Abdel
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- Hamilton Beatrice
- Hamilton Joanna
- Hamilton Ronald
- Hammonds John Christopher
- Hanna Emma
- Hannaford Zeta
- Happle Liz
- Hardie Maryon
- Harding Claudia
- Harding Joshua
- Hardman John
- Hardstaff Lisa
- Hare Jennifer A
- Hargreaves Carolyn
- Hargreaves Jeanette
- Hargreaves Jeanette
- Harinarayanan Sathish
- Harinarayanan Sathish
- Harland Keith
- Harney Jackie
- Harnwell Juliette
- Harpell Rhonda
- Harris (n. Marchant) Emily
- Harris Catherine
- Harris Sarah
- Harris-Burland Angie
- Harrison Alison
- Harrow Sister Kath
- Hart Amber
- Hart Andrew
- Harter Leah
- Hartley Jasmine
- Hartman Carrie
- Hartt Nancy
- Hartwell Lyn
- Harvey Julie
- Harvey Sally
- Harving Niels
- Haskell Annelise
- Hassall Alison
- Hassan Nebah
- Hassan Nebah
- Hathout Lara
- Hatimy Umi
- Haydock Helen
- Haydock Helen
- Hayes Jill A
- Hayward Lesley
- Healey Gail
- Healey-Mariano Jennifer
- Healey-Mariano Jennifer
- Heasley Karen
- Heath Catherine
- Heath Catherine M
- Heckford Louise
- Hedges Andy
- Heeley Janine
- Hefferon Billy
- Hegarty Gemma
- Hejlesen Finn
- Helou Joelle
- Hendel Debra
- Henry Ann
- Henry Ann
- Henry Ann
- Henry Ann
- Henry Joanne
- Henry Joanne
- Henson (nee Savidge) Verity
- Henson Helen
- Herasimtschuk Anna
- Herbert Chris
- Herbert Gaynor
- Heron Jane
- Hetherington Stacey
- Hicks Kimberly
- Higgins Linda
- Hijab Adham
- Hill Elaine
- Hill Judy
- Hill Pipa
- Hill Pippa
- Hillman Paul
- Hillman Paul
- Hilman Serena
- Hilman Serena
- Hindle Margaret
- Hines John
- Hoare Kathryn
- Hocking Christopher
- Hodder June
- Hodge Simon
- Hodges Samantha
- Hodgkinson Sheila
- Hodson Hayley
- Hodson Hayley
- Hogan Holly
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- Hogbin Emma
- Hogbin Emma
- Holbrook Andy
- Holbrook Becky
- Holden Simon
- Holdsworth Amanda
- Hollenhorst Helmut
- Holliday Samantha
- Hollingdale Abigail
- Hollis Keri
- Hollister Robert
- Holloway Caroline
- Holmes Evelyn
- Holwerda Eleanor
- Homer David
- Hood Marion
- Hooper Simon
- Hooton Georgia
- Hore Brendan
- Horne Rhian
- Hornzee Gillian
- Hornzee Gillian
- Horton Sarah
- Horwich Alan
- Hoskin Peter
- Hoskins Ashley
- Hoskins Chloe
- Hotine Jodie
- Hough Adele
- Hough Chris
- Houghton Fionnuala
- Houle Stefanie
- House Gail
- Howard Joanna
- Howard Lucy
- Howard Lucy
- Howitt Pamela
- Hsien John
- Hubley Lynn
- Huddart Robert
- Huddart Robert
- Hudson Zoe
- Hughes Claire
- Hughes Faye
- Hughes Hayley
- Hughes Joanne
- Hughes Kathryn
- Hughes Owen
- Hughes Robert
- Hughes Simon
- Hughes-Davies Luke
- Hugill Angela
- Hugill Angela
- Humber Caroline
- Humpreys Louise
- Hunt Allison
- Hunter Catherine
- Hunter William
- Hunting Liz
- Hutchinson Camille
- Hyde Katherine
- Hyde Katherine
- Hyde Katherine
- Hynds Sharon
- Ibrahim Azman
- Ingham Jo
- Ingle Charlotte
- Inman Hayley
- Innes Helen
- Iordanidi Elina
- Iqbal Fawaad
- Irwin P
- Isaew Andrea
- Iskender Amanda
- Islam Zaheer
- Issa Rami
- Ivie Stephanie
- Jackman Dee
- Jackson Cathy
- Jackson Kim
- Jackson Sister Ann
- Jain Suneil
- Jakeman Christine
- James Naomi
- James Nicholas
- James Nicholas D
- Jamieson Ceri
- Jampana Raj
- Janke Susan
- Jannapureddy Revanth
- Jarvis Claire
- Jastrzebska Patrycja
- Javle P
- Jayachandran Resmi
- Jayachandran Resmi
- Jeffcutt Nicole
- Jeffrey David
- Jelski Joseph
- Jenkins Peter
- Jenkins Suzanne
- Jenner Abigail
- Jennings Marian
- Jepson Debbie
- Jevons Cody
- Jewers Karen
- Jewers Karen
- Jeyasanger Ganesan
- Joe Howard
- John Babbin
- Johns Louise
- Johnson Arlissa
- Johnson Craig
- Johnson Joanne
- Johnson Lyndsey
- Johnson Nigel
- Johnson-Rollings Ashley
- Johnston Laurel
- Johnston Ruth
- Johnstone Dawn
- Johnstone Maria
- Joncas MarieClaude
- Jones (Birch) Janine
- Jones Andrea
- Jones Ania
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- Jones Cathryn
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- Jones Dawn
- Jones Gareth
- Jones Ifan
- Jones Jules
- Jones Julia
- Jones Kathryn
- Jones Katie
- Jones Lesley
- Jones Lewis
- Jones Richard
- Jones Rob
- Jones Stephanie
- Jones Stephanie
- Jones-Skipper Kay
- Jonnada Sai
- Jope Carmel
- Jose Sanal
- Joseph Joji
- Joseph Paul K
- Joshi Manisha
- Joshi Manisha
- Joslin Vicky
- Jovic Gordana
- Kaa Bach Birgit
- Kader Nicole
- Kalejaiye Odunayo
- Kaliski Alexandre
- Kalyvas Maria
- Kamran Asim
- Kanaga-Sundaram Subramanian
- Kancherla Kiran
- Kanji Femina
- Kanyi Karen
- Kapur Guarav
- Karim Omer
- Karp Stephen
- Karsera Louise
- Karunakaran Subashini
- Karvat Anand
- Kaushal Malan
- Kavanagh Roisin
- Kavanagh Roisin
- Kay Anne Marie
- Kazingizi Memory
- Keane Patrick
- Kearney S
- Kedge Liz
- Kehoe Laura
- Keith Sarah
- Keith Sarah
- Kelkar Anand
- Kellaway Joanne
- Kelly Alison
- Kelly Kay
- Kemp Gail
- Kempel Mette Moe
- Kendal Wayne S
- Keng-Koh Pek
- Keng-Koh Pek
- Keni Manjusha
- Kennedy Julie
- Kenny Shannon
- Kent Christopher
- Kent Emma
- Kenyon Lucille
- Kershaw Elizabeth
- Key Claire
- Keyes Mira
- Khaksar Sara
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- Khong Rachel
- Khoo Vincent
- Khoo Vincent
- Khoury Ghassan
- Kiff Janet
- Kift Shannon
- Kilmartin John
- Kilroy Stephen
- Kilroy Stephen
- Kiltie Anne
- Kiltie Anne
- Kim David
- Kim TuongVan
- Kim-Sing Charmaine
- KimSing Charmaine
- King Amy
- King Jennifer
- King Jennifer
- King Lisa
- Kinrade Yvonne
- KirbyBello Denise
- Kirk Christine
- Kirk Sister Sarah
- Kirkbride Peter
- Kirkbride Peter
- Kirkby Amy
- Kirkby Sarah
- Kirkpatrick Suriya
- Kisanga Mary
- Kitkowski Caitlin
- Klapp Kathi
- Klotz Laurence
- Klovgaard Karina
- Knackstedt Jochen
- Knapp Jeanette
- Knight (n. Sherburn) Victoria
- Knott Helen
- Knox WF
- Kockelbergh Roger
- Kodavatiganti Ravi
- Koehler Ingrid
- Kokholm Kathrine Friser
- Koll Wayne
- Kong Vickie
- Kotze Michelle
- Koul Rashmi
- Koulouris Zoe
- Koupparis Anthony
- Kowalczyk-Williams Wioletta
- Kowalewska Paulina
- Kronstal Flo
- Krysta Beata
- Kuenzig Greg
- Kujawa Magda
- Kuk Joda
- Kullane Sagal
- Kumar Daniel
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- Kumar Shiyam
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- Kurian-Downer Sunita
- Kurup Rahul
- Kuzyk Valerie
- Kwan Winkle
- Kyffin Phillippa
- Kynaston Howard
- Kynaston Howard
- Lacey Cathy
- Lachance Nicole
- Lactao Ranee
- Ladouceur Cynthia
- Laing Robert
- Lajoie MarieAndree
- Lake Sister Judith
- Lalani Nafisha
- Laliberte Benoit
- Lam Jacqueline
- Lambert Carole
- Lambert Katy
- Lamoureux Alexandra
- Lang Monika
- Langridge Nicole
- Laniado M
- Lao Bernadeth
- Larkins Rachel
- Larocque Stephanie
- Larouche Julie
- Larson Beverly
- Lassen Yasmin
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- Lau Maurice
- Laubscher Angelique
- Laughlin Anne
- Laursen Vibeke
- Lavender Helene
- Laverick Rosaleen
- Lavertu Sophie
- Lawless Claire
- Lawless Theresa
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- Lawrence Steph
- Lawrey Sarah
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- Leach Deborah
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- Leone Priscilla
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- Lewington Val
- Lewis Amanda
- Lewis Christina
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- Ley Samantha
- Li Audrey
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- Liau Joy
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- Lim Jan
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- Lipsham Margaret
- Liptrott Sarah
- Lister Debbie
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- Little Erin
- Little Jessica
- Littler John
- Littler Stephen
- Liu Stanley
- Livsey Jacqueline
- Livsey Jacqueline
- Lloyd-Jones Hugh
- Loblaw Douglas Andrew
- Lock Michael I
- Locke Angela
- Lockwood Carol
- Logue John
- Logue John
- Logue John
- Logue John
- Lokes Rachel
- Lokes Rachel
- Lomas Alia
- Lomas Claire
- Lomax Laurie
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- Loughlin Kate
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- Love Clare
- Love Sally
- Lowe Amelia
- Lowi Suzy
- Lucakova Slavka
- Lukka Himu
- Lunau Anne Sofie
- Lydon Anna
- Lydon Anne Marie
- Lynch Rory
- Lyons Ciara
- Mabelin Louies
- Macavoy Tina
- Macdonald Alison
- MacDonald Angela
- MacDonald Graham
- Macefield Rhiannon
- MacGregor Barbara
- Macgregor Carol
- MacIsaac Kathy
- MacIsaac Patricia
- Mackay Rachel
- Macleod Nicholas
- MacMillan Antonia
- MacMullin Lisa
- MacRae Robert M
- Macrory Joanne
- MacVicar Jennifer
- MacVicar Karen
- Madeleine Jude
- Madhava Kudingila
- Madine John
- Magwaro Sophia
- Magwaro Sophia
- Magwaro Sophia
- Mahmood Rana
- Mahmood Rana
- Mahmood Sana
- Mahmud Aamer
- Mahoney Catriona
- Mahoney Sue
- Maitland Katrina
- Maize Christine
- Majumdar Arpita
- Makepeace Barbara
- Malde Rohit
- Malek Leila
- Malik Zafar
- Mallett Debbie
- Malone Shawn
- Malone Shawn C
- Manetta Caroline
- Manganaro Aileen
- Mangar Stephen
- Maniatis Christos
- Manley Rachel
- Mannan Aliyah
- Manning Courtney
- Manning Kimberley
- Mansell Gemma
- Mansfield Carolyn
- Mantle Mark
- Manyangadze Sarah
- Marange Josephine
- Mardell Stephen
- Marek Kathleen
- Mariappan Param
- Marineau Line
- Mark Ian
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- Marley Hazel
- Marquis Tania
- Marriott Sue
- Marshall John
- Marshall Lynn
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- Marston Kerrie
- Martin AndreGuy
- Martin Jackie
- Martin Joseph
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- Martindale John
- Martindale John
- Martindale John
- Martinez Maria
- Martinou Maria
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- Marty Janet
- Mashegede Beverley
- Mason Jessica
- Mason Malcolm
- Masson Susan
- Masson Susan
- Masters Benjamin
- Masters Lindsey
- Matkins Ellen
- Matthews Laura
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- Mayer Heather
- Mayne Barbara
- Mazhar Danish
- McAleese Jonathan
- McAlister Judy
- McAllister Jo
- McAuliffe Sarah
- McBain Hazel
- McBride Julia
- McCabe Alastair
- McCadden Angela
- McCarth Fiona
- McCartin Fiona
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- Smedley (nee McCabe) Janine
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- Turley Claudia
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- Varley Gail
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- Varughese Mohini
- Vasanthan Subramanian
- Vaughn Jamie
- Vavassis Peter
- Velec Erin
- Vengalil Salil
- Venkatesan Varagur M
- Venkitaraman Ramachandran
- Venkitaraman Ramachandran
- Vermette Tracy
- Vesprini Danny
- Vickery Kathryn
- Vigneault Eric
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- Vilarino-Varela Maria
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- Walsh Donna
- Walton Jenny
- Walton Sharon
- Ward Angela
- Ward Colin
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- Waring Lynsey
- Waring Lynsey
- Wassall Rebecca
- Watkinson Catrin
- Watson Melanie R
- Watson Michaella
- Watson-Jones Phillip
- Watts Angela
- Watts Erica
- Weaver Andrew
- Weaver Emma
- Webb Andrew
- Webb Claire
- Webb Kerrie
- Webb Paula
- Websdale Cheryl
- Webster Christine
- Wei Joyce
- Weir JoAnn
- Wellman Sandie
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- Wells Paula
- Wells Paula
- Wells Tom
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- Welsh Linda
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- Weston Alison
- Weston Philip
- Westrop Anna
- Westrop Anna
- Westrop Anna
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- Wheelwright Roger
- Whelan Kate
- Whillis David
- Whinn Samantha
- Whitcher Alison
- White Ann
- White Holly
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- Whitehouse James
- Whiteway Chrystal
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- Wightman John
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- Wilke Derek
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- Wilkinson Nicola
- Williams (Née Allen) Sister Tania
- Williams Amanda
- Williams Bethan
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- Williams Jo
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- Williams Rachel
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- Williams-Yesson Barbara
- Williamson Elizabeth
- Williamson Nicola
- Willing Stephanie
- Wilson David
- Wilson Jim
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- Wilson Mark
- Wilson Paula
- Wilson Paula
- Wilson Russ
- Winn Carol
- Winter Sister Helen
- Wise Marcus
- Wise Marcus
- Wise Marcus
- Wiss Elliott
- Wollaston Julie
- Woloshyn Rose
- Wong Jason W T
- Wood Allison
- Wood Catherine
- Wood Cathryn
- Wood Marian
- Wood Pauline
- Wood Pauline
- Wood Sister Kim
- Wood Sister Kim
- Wood Sister Kim
- Woodhouse Iain
- Woods Catherine
- Woods Jane
- Woods Martin
- Woodward Cathryn
- Woodward Elizabeth
- Woolf David
- Woolf David
- Workman Bridget
- Worlding Jane
- Worlding Jane
- Worsley Lucy
- Worthington Hannah
- Wright Ann
- Wright Natalie
- Wright Seonaid
- Wrigley Martha
- Wronski Sue
- Wu Helen
- Wu Min
- Wyatt Clare
- Wylie James
- Wylie James
- Wylie James
- Wynn Hazel
- Wynn Hazel
- Yanchuk Janet
- Yarrow Sue
- Yassa Michael
- yates Victoria
- Yee Don
- Yeo Tanya
- Yoon Frederick
- Youd Sister Jill
- Young Anita
- Young Bobbie
- Young Douglas
- Young Sally
- Youngs Nora
- Yu Jason
- Yunace Lorrie
- Yusof Hilawati
- Zafar Waheed
- Zaidi Sadaf
- Zarkar Anjali
- Zarkar Anjali
- Zaza Khaled O
- Zelley Sarah
- Zeltser Fred
- Zhang Hanbo
- Zhang Tina Wanting
- Zietz Maria
- Zilkha Helene
- Zinck Connie
- Zinyemba Vivian
- Zurakovsky Hilary
- Zwarych Darlene
- Publication venue
- Elsevier
- Publication date
- 07/06/2024
- Field of study
Background
Previous evidence supports androgen deprivation therapy (ADT) with primary radiotherapy as initial treatment for intermediate-risk and high-risk localised prostate cancer. However, the use and optimal duration of ADT with postoperative radiotherapy after radical prostatectomy remains uncertain.
Methods
RADICALS-HD was a randomised controlled trial of ADT duration within the RADICALS protocol. Here, we report on the comparison of short-course versus long-course ADT. Key eligibility criteria were indication for radiotherapy after previous radical prostatectomy for prostate cancer, prostate-specific antigen less than 5 ng/mL, absence of metastatic disease, and written consent. Participants were randomly assigned (1:1) to add 6 months of ADT (short-course ADT) or 24 months of ADT (long-course ADT) to radiotherapy, using subcutaneous gonadotrophin-releasing hormone analogue (monthly in the short-course ADT group and 3-monthly in the long-course ADT group), daily oral bicalutamide monotherapy 150 mg, or monthly subcutaneous degarelix. Randomisation was done centrally through minimisation with a random element, stratified by Gleason score, positive margins, radiotherapy timing, planned radiotherapy schedule, and planned type of ADT, in a computerised system. The allocated treatment was not masked. The primary outcome measure was metastasis-free survival, defined as metastasis arising from prostate cancer or death from any cause. The comparison had more than 80% power with two-sided α of 5% to detect an absolute increase in 10-year metastasis-free survival from 75% to 81% (hazard ratio [HR] 0·72). Standard time-to-event analyses were used. Analyses followed intention-to-treat principle. The trial is registered with the ISRCTN registry, ISRCTN40814031, and
ClinicalTrials.gov
,
NCT00541047
.
Findings
Between Jan 30, 2008, and July 7, 2015, 1523 patients (median age 65 years, IQR 60–69) were randomly assigned to receive short-course ADT (n=761) or long-course ADT (n=762) in addition to postoperative radiotherapy at 138 centres in Canada, Denmark, Ireland, and the UK. With a median follow-up of 8·9 years (7·0–10·0), 313 metastasis-free survival events were reported overall (174 in the short-course ADT group and 139 in the long-course ADT group; HR 0·773 [95% CI 0·612–0·975]; p=0·029). 10-year metastasis-free survival was 71·9% (95% CI 67·6–75·7) in the short-course ADT group and 78·1% (74·2–81·5) in the long-course ADT group. Toxicity of grade 3 or higher was reported for 105 (14%) of 753 participants in the short-course ADT group and 142 (19%) of 757 participants in the long-course ADT group (p=0·025), with no treatment-related deaths.
Interpretation
Compared with adding 6 months of ADT, adding 24 months of ADT improved metastasis-free survival in people receiving postoperative radiotherapy. For individuals who can accept the additional duration of adverse effects, long-course ADT should be offered with postoperative radiotherapy.
Funding
Cancer Research UK, UK Research and Innovation (formerly Medical Research Council), and Canadian Cancer Society
Les débuts du hockey montréalais, 1875-1917
- Author
- Publication venue
- 'OpenEdition'
- Publication date
- 14/11/2019
- Field of study
Le hockey a récemment reçu ses lettres de noblesse de la part du gouvernement canadien, à savoir le "sport national d'hiver", tandis que la crosse en est le pendant estival. Sous le leadership du néo-démocrate Nelson Riess, ce projet de loi privé vient confirmer ce que tous et chacun savaient depuis longtemps. La loi C-212 a été déposée le 27 avril 1994, et a reçu la sanction royale le 12 mai suivant. Cependant, peu de gens connaissent réellement son histoire, principalement en ce qui concern..
Les débuts du hockey organisé
- Author
- Publication venue
- 'Consortium Erudit'
- Publication date
- 01/01/2013
- Field of study
Monte Carlo dosimetry of high dose rate gynecologic interstitial brachytherapy
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/12/2013
- Field of study
Partage d’informations et respect de la confidentialité : repères pour améliorer la qualité des services en santé mentale
- Author
- Publication venue
- Érudit
- Publication date
- 01/01/2023
- Field of study
Objectifs La collaboration entre les personnes proches aidantes (PPA) et les professionnels joue un rôle déterminant dans le rétablissement de la personne vivant avec un trouble mental. Cependant, les pratiques collaboratives entre les PPA et les professionnels se heurtent à des enjeux de confidentialité, particulièrement lorsqu’il est question de partager des informations de manière bidirectionnelle entre les acteurs impliqués. Ce faisant, ces enjeux nuisent à la qualité des services offerts en santé mentale.Méthode Une étude qualitative a permis de rencontrer 19 PPA et 19 professionnels en santé mentale de 2 régions du Québec afin d’identifier les enjeux liés au partage d’informations et au respect de la confidentialité à partir de leur perspective croisée. Des entretiens individuels semi-dirigés ont été réalisés auprès des 38 participants.Résultats La confidentialité et le refus de la personne vivant avec un trouble mental à consentir au partage d’informations demeurent des obstacles importants et actuels dans les pratiques en santé mentale. L’organisation des services en santé mentale devrait assurer une meilleure intégration des PPA dans les équipes afin qu’elles puissent contribuer au rétablissement de la personne et ainsi, recevoir tout le soutien et les informations dont elles ont besoin pour exercer leur rôle. Il ressort de l’étude que les PPA ont différents besoins d’information pour exercer leur rôle et accompagner la personne vivant avec un trouble mental, dont celui d’avoir des renseignements généraux et non confidentiels pour mieux soutenir cette dernière. Tout en respectant les droits fondamentaux et l’autonomie de la personne qui est libre de consentir ou non au partage d’informations la concernant, les professionnels et les PPA peuvent tout de même avoir des échanges et créer une alliance qui favorise l’établissement de collaborations et le rétablissement.Conclusion Cet article offre des repères afin de faciliter le dialogue entre les personnes vivant avec un trouble mental, les PPA et les professionnels et de les soutenir dans leurs actions en matière de partage d’informations et de respect de la confidentialité dans les pratiques en santé mentale. Ultimement, l’intention est de favoriser des pratiques collaboratives qui contribueront à améliorer la qualité des services en santé mentale.Objectives Collaboration between family caregivers and professionals plays a critical role in the recovery of the person living with a mental health disorder. However, collaborative practices between family caregivers and professionals are impeded by issues relating to confidentiality, particularly in connection with bidirectional information sharing between the parties involved. In doing so, these issues affect the quality of mental health services.Method A qualitative study was conducted with 19 family caregivers and 19 mental health professionals from 2 Quebec regions in order to identify issues related to information sharing and confidentiality from their combined perspective. The Photovoice method was used and individuals semi-directed interviews were conducted with the 38 participants.Results Confidentiality and the refusal of the person living with a mental health disorder to consent to share information remains important and current obstacles in mental health practises. The organization of mental health services should ensure better integration of family caregivers into care teams so that they can contribute to the person’s recovery and thus receive all the support and information they need to exercise their role. This study shows that family caregivers have different information needs in order to carry out their role and accompany the person living with a mental health disorder, including the need for general and non-confidential information to better support the person. While respecting the fundamental rights and autonomy of the person, who is free to consent or not to sharing information concerning him or her, professionals and family caregivers can still interact and create an alliance that promotes collaboration and recovery.Conclusion This article offers benchmarks to facilitate dialogue among people living with a mental health disorder, family caregivers and professionals, and to support their actions around information-sharing and respect for confidentiality in mental health practises. Ultimately, the intention here is to foster collaborative practices that will help improve the quality of mental health services