33 research outputs found

    Thermal versus quantum fluctuations of optical-lattice fermions

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    We show that, for fermionic atoms in a one-dimensional optical lattice, the fraction of atoms in doubly occupied sites is a highly nonmonotonic function of temperature. We demonstrate that this property persists even in the presence of realistic harmonic confinement, and that it leads to a suppression of entropy at intermediate temperatures that offers a route to adiabatic cooling. Our interpretation of the suppression is that such intermediate temperatures are simultaneously too high for quantum coherence and too low for significant thermal excitation of double occupancy thus offering a clear indicator of the onset of quantum fluctuations.Publisher PDFPeer reviewe

    Friedel oscillations in one-dimensional metals: from Luttinger's theorem to the Luttinger liquid

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    Charge density and magnetization density profiles of one-dimensional metals are investigated by two complementary many-body methods: numerically exact (Lanczos) diagonalization, and the Bethe-Ansatz local-density approximation with and without a simple self-interaction correction. Depending on the magnetization of the system, local approximations reproduce different Fourier components of the exact Friedel oscillations.Comment: 3 pages, 3 figures, Manuscript accepted by Journal of Magnetism and Magnetic Materials, special issue for LAWMMM 2007 conferenc

    Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

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    BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

    Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma

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    Genome-wide association studies (GWAS) have transformed our understanding of susceptibility to multiple myeloma (MM), but much of the heritability remains unexplained. We report a new GWAS, a meta-analysis with previous GWAS and a replication series, totalling 9974 MM cases and 247,556 controls of European ancestry. Collectively, these data provide evidence for six new MM risk loci, bringing the total number to 23. Integration of information from gene expression, epigenetic profiling and in situ Hi-C data for the 23 risk loci implicate disruption of developmental transcriptional regulators as a basis of MM susceptibility, compatible with altered B-cell differentiation as a key mechanism. Dysregulation of autophagy/apoptosis and cell cycle signalling feature as recurrently perturbed pathways. Our findings provide further insight

    Possible critical behavior driven by the confining potential in optical lattices with ultra-cold fermions

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    A recent paper [V. L. Campo et. al., Phys. Rev. Lett. 99, 240403 (2007) has proposed a two-parameter scaling method to determine the phase diagram of the fermionic Hubbard model from optical lattice experiments. Motivated by this proposal, we investigate in more detail, the behavior of the ground-state energy per site as a function of trap size(L) and confining potential (V(x) = t(x/L)^alpha) in the one-dimensional case. Using the BALDA-DFT method, we find signatures of critical behavior as alpha goes to infinity.Comment: 4 pages, 4 Postscript figures, uses elsart5p.cls, elsart.cls, submitted as proceeding to SCES-08 (Strongly Correlated Electron Systems Meeting of 2008
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