1,700 research outputs found

    Corte Costituzionale e risarcimento del danno da sanzione sportiva

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    Muovendo da una significativa sentenza della Corte Costituzionale (11/2/2011, n. 49), e rivisitando il tradizionale tema dei rapporti tra ordinamento sportivo e ordinamento dello Stato, il saggio riflette sulla possibile rilevanza, in quest’ultimo, delle sanzioni sportive comminate dal Comitato Olimpico Nazionale Italiano o dalle Federazioni ad esso affiliate: e ciò quali possibili fatti illeciti ex art. 2043 cod. civ.

    Morphometry and debris-flow susceptibility map in mountain drainage basins of the Vallo di Diano, southern Italy

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    In watershed mountain basins, affected in the last decades by strong rainfall events, the role of debris-flow and debris flood processes was investigated. Morphometric parameters have proven to be useful first-approximation indicators in discriminating those processes, especially in large areas of investigation. Computation of morphometric parameters in 19 watershed mountain basins of the western side valley of the Vallo di Diano intermontane basin (southern Italy) was carried out. This procedure was integrated by a semi-automatic elaboration of the potential susceptibility to debris flows, using Flow-R modelling. This software, providing an empirical model of the preliminary susceptibility assessment at a regional scale, was applied in many countries of the world. The implementation of Flow-R modelling requires a GIS application and some thematic base maps extracted using DEMs analysis. A 5-meter-resolution DEM has been used in order to produce the susceptibility maps of the whole study area, and the results are compared and discussed with the real debris flow/flood events that occurred in 1993, 2005, 2010, and 2017 in the studied area. The results have provided a good reliability of Flow-R modelling within small catchment mountain basins

    The isoprenoid end product N6-isopentenyladenosine reduces inflammatory response through the inhibition of the NF\uce\ubaB and STAT3 pathways in cystic fibrosis cells

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    N6-isopentenyladenosine (iPA) is an intermediate of the mevalonate pathway that exhibits various anti-cancer effects. However, studies on its anti-inflammatory activity are scarce and underlying molecular mechanisms are unknown. Therefore, we aimed to investigate the ability of iPA to exert anti-inflammatory effects in the human cystic fibrosis (CF) cell model of exacerbated inflammation. TNF alpha-stimulated CF cells CuFi-1 and its normal counterpart NuLi-1 were pre-treated with increasing concentrations of iPA and cell viability and proliferation were assessed by MTT and BrdU assays. The effect of iPA on IL-8 and RANTES secretion was determined by ELISA, and the activation and expression of signaling molecules and selenoproteins were studied by Western blot. To assess the direct effect of iPA on NF kappa B activity, luciferase assay was performed on TNF alpha-stimulated HEK293/T cells transfected with a NF kappa B reporter plasmid. We demonstrated for the first time that iPA prevents IL-8 and RANTES release in TNF alpha-stimulated CF cells and this effect is mediated by increasing the expression of the direct NF kappa B inhibitor I kappa B alpha and decreasing the levels of STAT3. Consistent with this, we showed that iPA inhibited TNF alpha-mediated NF kappa B activation in HEK/293T cells. Finally, we also found that iPA improved the levels of glutathione peroxidase 1 and thioredoxin reductase 1 only in CF cells suggesting its ability to maintain sufficient expression of these anti-oxidant selenoproteins. Our findings indicate that iPA can exert anti-inflammatory activity especially in the cases of excessive inflammatory response as in CF

    Measurement of the CKM angle γ from a combination of B±→Dh± analyses

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    A combination of three LHCb measurements of the CKM angle γ is presented. The decays B±→D K± and B±→Dπ± are used, where D denotes an admixture of D0 and D0 mesons, decaying into K+K−, π+π−, K±π∓, K±π∓π±π∓, K0Sπ+π−, or K0S K+K− final states. All measurements use a dataset corresponding to 1.0 fb−1 of integrated luminosity. Combining results from B±→D K± decays alone a best-fit value of γ =72.0◦ is found, and confidence intervals are set γ ∈ [56.4,86.7]◦ at 68% CL, γ ∈ [42.6,99.6]◦ at 95% CL. The best-fit value of γ found from a combination of results from B±→Dπ± decays alone, is γ =18.9◦, and the confidence intervals γ ∈ [7.4,99.2]◦ ∪ [167.9,176.4]◦ at 68% CL are set, without constraint at 95% CL. The combination of results from B± → D K± and B± → Dπ± decays gives a best-fit value of γ =72.6◦ and the confidence intervals γ ∈ [55.4,82.3]◦ at 68% CL, γ ∈ [40.2,92.7]◦ at 95% CL are set. All values are expressed modulo 180◦, and are obtained taking into account the effect of D0–D0 mixing

    Observation of an Excited Bc+ State

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    Using pp collision data corresponding to an integrated luminosity of 8.5 fb-1 recorded by the LHCb experiment at center-of-mass energies of s=7, 8, and 13 TeV, the observation of an excited Bc+ state in the Bc+π+π- invariant-mass spectrum is reported. The observed peak has a mass of 6841.2±0.6(stat)±0.1(syst)±0.8(Bc+) MeV/c2, where the last uncertainty is due to the limited knowledge of the Bc+ mass. It is consistent with expectations of the Bc∗(2S31)+ state reconstructed without the low-energy photon from the Bc∗(1S31)+→Bc+γ decay following Bc∗(2S31)+→Bc∗(1S31)+π+π-. A second state is seen with a global (local) statistical significance of 2.2σ (3.2σ) and a mass of 6872.1±1.3(stat)±0.1(syst)±0.8(Bc+) MeV/c2, and is consistent with the Bc(2S10)+ state. These mass measurements are the most precise to date

    Observation of associated production of a ZZ boson with a DD meson in the~forward region

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    A search for associated production of a ZZ boson with an open charm meson is presented using a data sample, corresponding to an integrated luminosity of 1.0fb1.0\,\mathrm{fb}^{-`} of proton--proton collisions at a centre-of-mass energy of 7\,TeV, collected by the LHCb experiment. %% Seven candidate events for associated production of a ZZ boson with a D0D^0 meson and four candidate events for a ZZ boson with a D+D^+ meson are observed with a combined significance of 5.1standard deviations. The production cross-sections in the forward region are measured to be σZμ+μ ⁣,D0=2.50±1.12±0.22pb\sigma_{Z\rightarrow\mu^+\mu^-\!,D^0} = 2.50\pm1.12\pm0.22pb σZμ+μ ⁣,D+=0.44±0.23±0.03pb,\sigma_{Z\rightarrow\mu^+\mu^-\!,D^+} = 0.44\pm0.23\pm0.03pb, where the first uncertainty is statistical and the second systematic.Comment: 18 pages, 2 figure

    Observation of two new Ξb\Xi_b^- baryon resonances

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    Two structures are observed close to the kinematic threshold in the Ξb0π\Xi_b^0 \pi^- mass spectrum in a sample of proton-proton collision data, corresponding to an integrated luminosity of 3.0 fb1^{-1} recorded by the LHCb experiment. In the quark model, two baryonic resonances with quark content bdsbds are expected in this mass region: the spin-parity JP=12+J^P = \frac{1}{2}^+ and JP=32+J^P=\frac{3}{2}^+ states, denoted Ξb\Xi_b^{\prime -} and Ξb\Xi_b^{*-}. Interpreting the structures as these resonances, we measure the mass differences and the width of the heavier state to be m(Ξb)m(Ξb0)m(π)=3.653±0.018±0.006m(\Xi_b^{\prime -}) - m(\Xi_b^0) - m(\pi^{-}) = 3.653 \pm 0.018 \pm 0.006 MeV/c2/c^2, m(Ξb)m(Ξb0)m(π)=23.96±0.12±0.06m(\Xi_b^{*-}) - m(\Xi_b^0) - m(\pi^{-}) = 23.96 \pm 0.12 \pm 0.06 MeV/c2/c^2, Γ(Ξb)=1.65±0.31±0.10\Gamma(\Xi_b^{*-}) = 1.65 \pm 0.31 \pm 0.10 MeV, where the first and second uncertainties are statistical and systematic, respectively. The width of the lighter state is consistent with zero, and we place an upper limit of Γ(Ξb)<0.08\Gamma(\Xi_b^{\prime -}) < 0.08 MeV at 95% confidence level. Relative production rates of these states are also reported.Comment: 17 pages, 2 figure

    Bose-Einstein correlations of same-sign charged pions in the forward region in pp collisions at √s=7 TeV

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    Bose-Einstein correlations of same-sign charged pions, produced in protonproton collisions at a 7 TeV centre-of-mass energy, are studied using a data sample collected by the LHCb experiment. The signature for Bose-Einstein correlations is observed in the form of an enhancement of pairs of like-sign charged pions with small four-momentum difference squared. The charged-particle multiplicity dependence of the Bose-Einstein correlation parameters describing the correlation strength and the size of the emitting source is investigated, determining both the correlation radius and the chaoticity parameter. The measured correlation radius is found to increase as a function of increasing charged-particle multiplicity, while the chaoticity parameter is seen to decreas

    Measurements of the B+B^+, B0B^0, Bs0B_s^0 meson and Λb0\Lambda_b^0 baryon lifetimes

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    Measurements of bb-hadron lifetimes are reported using pppp collision data, corresponding to an integrated luminosity of 1.0fb1^{-1}, collected by the LHCb detector at a centre-of-mass energy of 77Tev. Using the exclusive decays B+J/ψK+B^+\to J/\psi K^+, B0J/ψK(892)0B^0\to J/\psi K^*(892)^0, B0J/ψKS0B^0\to J/\psi K^0_{\rm S}, Λb0J/ψΛ\Lambda_b^0\to J/\psi \Lambda and Bs0J/ψϕB^0_s\to J/\psi \phi the average decay times in these modes are measured to be τB+J/ψK+\tau_{B^+\to J/\psi K^+} = 1.637±1.637 \pm 0.004 ±\pm 0.003 ps, τB0J/ψK(892)0\tau_{B^0\to J/\psi K^*(892)^0} = 1.524±1.524 \pm 0.006 ±\pm 0.004 ps, τB0J/ψKS0\tau_{B^0\to J/\psi K^0_{\rm S}} = 1.499±1.499 \pm 0.013 ±\pm 0.005 ps, τΛb0J/ψΛ\tau_{\Lambda_b^0\to J/\psi \Lambda} = 1.415±1.415 \pm 0.027 ±\pm 0.006 ps and τBs0J/ψϕ\tau_{B^0_s\to J/\psi \phi} = 1.480±1.480 \pm 0.011 ±\pm 0.005 ps, where the first uncertainty is statistical and the second is systematic. These represent the most precise lifetime measurements in these decay modes. In addition, ratios of these lifetimes, and the ratio of the decay-width difference, ΔΓd\Delta\Gamma_d, to the average width, Γd\Gamma_d, in the B0B^0 system, ΔΓd/Γd=0.044±0.025±0.011\Delta \Gamma_d/\Gamma_d = -0.044 \pm 0.025 \pm 0.011, are reported. All quantities are found to be consistent with Standard Model expectations.Comment: 28 pages, 4 figures. Updated reference

    Measurement of the mass and lifetime of the Ωb\Omega_b^- baryon

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    A proton-proton collision data sample, corresponding to an integrated luminosity of 3 fb1^{-1} collected by LHCb at s=7\sqrt{s}=7 and 8 TeV, is used to reconstruct 63±963\pm9 ΩbΩc0π\Omega_b^-\to\Omega_c^0\pi^-, Ωc0pKKπ+\Omega_c^0\to pK^-K^-\pi^+ decays. Using the ΞbΞc0π\Xi_b^-\to\Xi_c^0\pi^-, Ξc0pKKπ+\Xi_c^0\to pK^-K^-\pi^+ decay mode for calibration, the lifetime ratio and absolute lifetime of the Ωb\Omega_b^- baryon are measured to be \begin{align*} \frac{\tau_{\Omega_b^-}}{\tau_{\Xi_b^-}} &= 1.11\pm0.16\pm0.03, \\ \tau_{\Omega_b^-} &= 1.78\pm0.26\pm0.05\pm0.06~{\rm ps}, \end{align*} where the uncertainties are statistical, systematic and from the calibration mode (for τΩb\tau_{\Omega_b^-} only). A measurement is also made of the mass difference, mΩbmΞbm_{\Omega_b^-}-m_{\Xi_b^-}, and the corresponding Ωb\Omega_b^- mass, which yields \begin{align*} m_{\Omega_b^-}-m_{\Xi_b^-} &= 247.4\pm3.2\pm0.5~{\rm MeV}/c^2, \\ m_{\Omega_b^-} &= 6045.1\pm3.2\pm 0.5\pm0.6~{\rm MeV}/c^2. \end{align*} These results are consistent with previous measurements.Comment: 11 pages, 5 figures, All figures and tables, along with any supplementary material and additional information, are available at https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2016-008.htm
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