Propuesta de actividades lúdicas y recreativas para estudiantes de los XII grado del Instituto Urracá que no poseen dentro del programa curricular la materia de educación física.

Objetivo General: Desarrollar actividades lúdicas y recreativas entre los estudiantes de los 12° del Instituto Urracá que no cuentan con la asignatura dentro del curriculum; a fin de captar talentos, despertar interés y fortalecer la salud integral de estos alumnos. Objetivos Específicos: >Verificar mediante encuestas qué tipos de actividades realizan los estudiantes en su tiempo libre. >Diseñar actividades lúdicas y recreativas para estudiantes de los 12°del Instituto Urracá. >Habilitar el área estipulada en los planos para juegos lúdicos y recreativos. > Implementar el diseño de actividades lúdicas y recreativas destinadas a los estudiantes en el 12° en el Instituto Urracá

Told through the wine: a liquid chromatography-mass spectrometry interplatform comparison reveals the influence of the global approach on the final annotated metabolites in non-targeted metabolomics

This work focuses on the influence of the selected LC-HRMS platform on the final annotated compounds in non-targeted metabolomics. Two platforms that differed in columns, mobile phases, gradients, chromatographs, mass spectrometers (Orbitrap [Platform#1] and Q-TOF [Platform#2]), data processing and marker selection protocols were compared. A total of 42 wines samples from three different protected denomination of origin (PDO) were analyzed. At the feature level, good (O)PLS-DA models were obtained for both platforms (Q2[Platform#1]=0.89, 0.83 and 0.72; Q2[Platform#2]=0.86, 0.86 and 0.77 for Penedes, Ribera del Duero and Rioja wines respectively) with 100% correctly classified samples in all cases. At the annotated metabolite level, platforms proposed 9 and 8 annotated metabolites respectively which were identified by matching standards or the MS/MS spectra of the compound. At this stage, none of the suggested metabolites was coincident between platforms. When screened on the raw data, 6 and 5 of these compounds were detected on the other platform with a similar trend. Some of the detected metabolites showed complimentary information when integrated on biological pathways. Through the use of some examples at the annotated metabolite level, possible explanations of this initial divergence on the results are presented. This work shows the complications that may arise on the comparison of non-targeted metabolomics platforms even when metabolite focused approaches are used in the identificatio

M/TiO2 (M = Fe, Co, Ni, Cu, Zn) catalysts for photocatalytic hydrogen production under UV and visible light irradiation

In order to improve the photocatalytic response of TiO2 to UV and visible light for hydrogen photoproduction, low cost M/TiO2 semiconductor catalysts were prepared by the impregnation method of five different first row transition metals (M = Fe, Co, Ni, Cu or Zn) on a commercial titania support. The maximum hydrogen production efficiency was achieved for the Cu/TiO2 photocatalyst, with ∼5000 and ∼220 μmol h−1 g−1 H2 production rates for UV and visible irradiation, respectively. Ni/TiO2 and Co/TiO2 also showed a significant photocatalytic activity when UV light was used. The best performing catalyst, Cu/TiO2, was characterized by TEM and XPS measurements. The data showed that Cu was highly dispersed over the TiO2 support and the copper species existed as both reduced Cu0/Cu+ and oxidized Cu2+ on TiO2. Besides, during the hydrogen production reaction, the reduced Cu was partially oxidized to Cu2+ by the transfer of photogenerated holes under UV or visible light irradiation. With UV and visible lamps, the H2 production rates were higher than those obtained with non-impregnated TiO2 by factors of 16 and 3, respectively. These results demonstrated that a Cu/TiO2 photocatalyst could be considered a promising low-cost alternative to the well-known Pt/TiO2 system for hydrogen production, making the Cu-based catalyst an ideal cost-effective candidate for this reactionThe authors would like to thank Ministerio de Economía y Competitividad of Spain (CTQ2015-68951-C3-3-R and MAT2016-80933-R), Ministerio de Ciencia, Innovación y Universidades of Spain (Project RTI2018-099668-B-C22) and FEDER fund

Disconnecting Symmetry Breaking from Seeded Growth for the Reproducible Synthesis of High Quality Gold Nanorods

https://pubs.acs.org/doi/suppl/10.1021/acsnano.8b09658/suppl_file/nn8b09658_si_002.pdfOne of the major difficulties hindering the widespread application of colloidal anisotropic plasmonic nanoparticles is the limited robustness and reproducibility of multistep synthetic methods. We demonstrate herein that the reproducibility and reliability of colloidal gold nanorod (AuNR) synthesis can be greatly improved by disconnecting the symmetry-breaking event from the seeded growth process. We have used a modified silver-assisted seeded growth method in the presence of the surfactant hexadecyltrimethylammonium bromide and n-decanol as a co-surfactant to prepare small AuNRs in high yield, which were then used as seeds for the growth of high quality AuNR colloids. Whereas the use of n-decanol provides a more-rigid micellar system, the growth on anisotropic seeds avoids sources of irreproducibility during the symmetry breaking step, yielding uniform AuNR colloids with narrow plasmon bands, ranging from 600 to 1270 nm, and allowing the fine-tuning of the final dimensions. This method provides a robust route for the preparation of high quality AuNR colloids with tunable morphology, size, and optical response in a reproducible and scalable manner

Exploring the effects of high-velocity flows in abundance determinations in H II regions. Bidimensional spectroscopy of HH 204 in the Orion Nebula

We present results from integral field optical spectroscopy with the Potsdam Multi-Aperture Spectrograph of the Herbig-Haro (HH) object HH 204, with a spatial sampling of 1 x 1 arcsec^2. We have obtained maps of different emission lines, physical conditions and ionic abundances from collisionally excited lines. The ionization structure of the object indicates that the head of the bow shock is optically thick and has developed a trapped ionization front. The density at the head is at least five times larger than in the background ionized gas. We discover a narrow arc of high T_e([N II]) values delineating the southeast edge of the head. The temperature in this zone is about 1,000 K higher than in the rest of the field and should correspond to a shock-heated zone at the leading working surface of the gas flow. This is the first time this kind of feature is observed in a photoionized HH object. We find that the O^+ and O abundance maps show anomalous values at separate areas of the bow shock probably due to: a) overestimation of the collisional de-excitation effects of the [O II] lines in the compressed gas at the head of the bow shock, and b) the use of a too high T_e([N II]) at the area of the leading working surface of the flow.Comment: 12 pages, 7 Postscript figures, accepted for publication in MNRA

mHealth intervention to improve quality of life in patients with chronic diseases during the COVID-19 crisis in Paraguay: A study protocol for a randomized controlled trial

Background Patients with chronic disease represent an at-risk group in the face of the COVID-19 crisis as they need to regularly monitor their lifestyle and emotional management. Coping with the illness becomes a challenge due to supply problems and lack of access to health care facilities. It is expected these limitations, along with lockdown and social distancing measures, have affected the routine disease management of these patients, being more pronounced in low- and middle-income countries with a flawed health care system. Objectives The purpose of this study is to describe a protocol for a randomized controlled trial to test the efficacy of the Adhera® MejoraCare Digital Program, an mHealth intervention aimed at improving the quality of life of patients with chronic diseases during the COVID-19 outbreak in Paraguay. Method A two-arm randomized controlled trial will be carried out, with repeated measures (baseline, 1-month, 3-month, 6-month, and 12-month) under two conditions: Adhera® MejoraCare Digital Program or waiting list. The primary outcome is a change in the quality of life on the EuroQol 5-Dimensions 3-Levels Questionnaire (EQ-5D-3L). Other secondary outcomes, as the effect on anxiety and health empowerment, will be considered. All participants must be 18 years of age or older and meet the criteria for chronic disease. A total of 96 participants will be recruited (48 per arm). Conclusions It is expected that the Adhera® MejoraCare Digital Program will show significant improvements in quality of life and emotional distress compared to the waiting list condition. Additionally, it is hypothesized that this intervention will be positively evaluated by the participants in terms of usability and satisfaction. The findings will provide new insights into the viability and efficacy of mHealth solutions for chronic disease management in developing countries and in times of pandemic

Azimuthal asymmetry in the risetime of the surface detector signals of the Pierre Auger Observatory

The azimuthal asymmetry in the risetime of signals in Auger surface detector stations is a source of information on shower development. The azimuthal asymmetry is due to a combination of the longitudinal evolution of the shower and geometrical effects related to the angles of incidence of the particles into the detectors. The magnitude of the effect depends upon the zenith angle and state of development of the shower and thus provides a novel observable, $(\sec \theta)_\mathrm{max}$, sensitive to the mass composition of cosmic rays above $3 \times 10^{18}$ eV. By comparing measurements with predictions from shower simulations, we find for both of our adopted models of hadronic physics (QGSJETII-04 and EPOS-LHC) an indication that the mean cosmic-ray mass increases slowly with energy, as has been inferred from other studies. However, the mass estimates are dependent on the shower model and on the range of distance from the shower core selected. Thus the method has uncovered further deficiencies in our understanding of shower modelling that must be resolved before the mass composition can be inferred from $(\sec \theta)_\mathrm{max}$.Comment: Replaced with published version. Added journal reference and DO