1,349 research outputs found
GABA-enhanced collective behavior in neuronal axons underlies persistent gamma-frequency oscillations
Gamma (30–80 Hz) oscillations occur in mammalian electroencephalogram in a manner that indicates cognitive relevance. In vitro models of gamma oscillations demonstrate two forms of oscillation: one occurring transiently and driven by discrete afferent input and the second occurring persistently in response to activation of excitatory metabotropic receptors. The mechanism underlying persistent gamma oscillations has been suggested to involve gap-junctional communication between axons of principal neurons, but the precise relationship between this neuronal activity and the gamma oscillation has remained elusive. Here we demonstrate that gamma oscillations coexist with high-frequency oscillations (>90 Hz). High-frequency oscillations can be generated in the axonal plexus even when it is physically isolated from pyramidal cell bodies. They were enhanced in networks by nonsomatic -aminobutyric acid type A (GABAA) receptor activation, were modulated by perisomatic GABAA receptor-mediated synaptic input to principal cells, and provided the phasic input to interneurons required to generate persistent gamma-frequency oscillations. The data suggest that high-frequency oscillations occurred as a consequence of random activity within the axonal plexus. Interneurons provide a mechanism by which this random activity is both amplified and organized into a coherent network rhythm
A role for fast rhythmic bursting neurons in cortical gamma oscillations in vitro
Basic cellular and network mechanisms underlying gamma frequency oscillations (30–80 Hz) have been well characterized in the hippocampus and associated structures. In these regions, gamma rhythms are seen as an emergent property of networks of principal cells and fast-spiking interneurons. In contrast, in the neocortex a number of elegant studies have shown that specific types of principal neuron exist that are capable of generating powerful gamma frequency outputs on the basis of their intrinsic conductances alone. These fast rhythmic bursting (FRB) neurons (sometimes referred to as "chattering" cells) are activated by sensory stimuli and generate multiple action potentials per gamma period. Here, we demonstrate that FRB neurons may function by providing a large-scale input to an axon plexus consisting of gap-junctionally connected axons from both FRB neurons and their anatomically similar counterparts regular spiking neurons. The resulting network gamma oscillation shares all of the properties of gamma oscillations generated in the hippocampus but with the additional critical dependence on multiple spiking in FRB cells
Test results of Spacelab 2 infrared telescope focal plane
The small helium cooled infrared telescope for Spacelab 2 is designed for sensitive mapping of extended, low-surface-brightness celestial sources as well as highly sensitive investigations of the shuttle contamination environment (FPA) for this mission is described as well as the design for a thermally isolated, self-heated J-FET transimpedance amplifier. This amplifier is Johnson noise limited for feedback resistances from less than 10 to the 8th power Omega to greater than 2 x 10 to the 10th power Omega at T = 4.2K. Work on the focal plane array is complete. Performance testing for qualification of the flight hardware is discussed, and results are presented. All infrared data channels are measured to be background limited by the expected level of zodiacal emission
Imaging the asymmetric dust shell around CI Cam with long baseline optical interferometry
We present the first high angular resolution observation of the B[e]
star/X-ray transient object CI Cam, performed with the two-telescope Infrared
Optical Telescope Array (IOTA), its upgraded three-telescope version (IOTA3T)
and the Palomar Testbed Interferometer (PTI). Visibilities and closure phases
were obtained using the IONIC-3 integrated optics beam combiner. CI Cam was
observed in the near-infrared H and K spectral bands, wavelengths well suited
to measure the size and study the geometry of the hot dust surrounding CI Cam.
The analysis of the visibility data over an 8 year period from soon after the
1998 outburst to 2006 shows that the dust visibility has not changed over the
years. The visibility data shows that CI Cam is elongated which confirms the
disc-shape of the circumstellar environment and totally rules out the
hypothesis of a spherical dust shell. Closure phase measurements show direct
evidence of asymmetries in the circumstellar environment of CI Cam and we
conclude that the dust surrounding CI Cam lies in an inhomogeneous disc seen at
an angle. The near-infrared dust emission appears as an elliptical skewed
Gaussian ring with a major axis a = 7.58 +/- 0.24 mas, an axis ratio r = 0.39
+/- 0.03 and a position angle theta = 35 +/- 2 deg.Comment: 9 pages, 5 figures, accepted MNRA
First visual orbit for the prototypical colliding-wind binary WR 140
Wolf-Rayet stars represent one of the final stages of massive stellar
evolution. Relatively little is known about this short-lived phase and we
currently lack reliable mass, distance, and binarity determinations for a
representative sample. Here we report the first visual orbit for WR
140(=HD193793), a WC7+O5 binary system known for its periodic dust production
episodes triggered by intense colliding winds near periastron passage. The IOTA
and CHARA interferometers resolved the pair of stars in each year from
2003--2009, covering most of the highly-eccentric, 7.9 year orbit. Combining
our results with the recent improved double-line spectroscopic orbit of Fahed
et al. (2011), we find the WR 140 system is located at a distance of 1.67 +/-
0.03 kpc, composed of a WR star with M_WR = 14.9 +/- 0.5 Msun and an O star
with M_O = 35.9 +/- 1.3 Msun. Our precision orbit yields key parameters with
uncertainties times 6 smaller than previous work and paves the way for detailed
modeling of the system. Our newly measured flux ratios at the near-infrared H
and Ks bands allow an SED decomposition and analysis of the component
evolutionary states.Comment: Complete OIFITS dataset included via Data Conservancy Projec
New insights on the AU-scale circumstellar structure of FU Orionis
We report new near-infrared, long-baseline interferometric observations at
the AU scale of the pre-main-sequence star FU Orionis with the PTI, IOTA and
VLTI interferometers. This young stellar object has been observed on 42 nights
over a period of 6 years from 1998 to 2003. We have obtained 287 independent
measurements of the fringe visibility with 6 different baselines ranging from
20 to 110 meters in length, in the H and K bands. Our extensive (u,v)-plane
coverage, coupled with the published spectral energy distribution data, allows
us to test the accretion disk scenario. We find that the most probable
explanation for these observations is that FU Ori hosts an active accretion
disk whose temperature law is consistent with standard models. We are able to
constrain the geometry of the disk, including an inclination of 55 deg and a
position angle of 47 deg. In addition, a 10 percent peak-to-peak oscillation is
detected in the data (at the two-sigma level) from the longest baselines, which
we interpret as a possible disk hot-spot or companion. However, the oscillation
in our best data set is best explained with an unresolved spot located at a
projected distance of 10 AU at the 130 deg position angle and with a magnitude
difference of DeltaK = 3.9 and DeltaH = 3.6 mag moving away from the center at
a rate of 1.2 AU/yr. we propose to interpret this spot as the signature of a
companion of the central FU Ori system on an extremely eccentric orbit. We
speculate that the close encounter of this putative companion and the central
star could be the explanation of the initial photometric rise of the luminosity
of this object
First astronomical unit scale image of the GW Ori triple. Direct detection of a new stellar companion
Young and close multiple systems are unique laboratories to probe the initial
dynamical interactions between forming stellar systems and their dust and gas
environment. Their study is a key building block to understanding the high
frequency of main-sequence multiple systems. However, the number of detected
spectroscopic young multiple systems that allow dynamical studies is limited.
GW Orionis is one such system. It is one of the brightest young T Tauri stars
and is surrounded by a massive disk. Our goal is to probe the GW Orionis
multiplicity at angular scales at which we can spatially resolve the orbit. We
used the IOTA/IONIC3 interferometer to probe the environment of GW Orionis with
an astronomical unit resolution in 2003, 2004, and 2005. By measuring squared
visibilities and closure phases with a good UV coverage we carry out the first
image reconstruction of GW Ori from infrared long-baseline interferometry. We
obtain the first infrared image of a T Tauri multiple system with astronomical
unit resolution. We show that GW Orionis is a triple system, resolve for the
first time the previously known inner pair (separation 1.4 AU) and
reveal a new more distant component (GW Ori C) with a projected separation of
8 AU with direct evidence of motion. Furthermore, the nearly equal (2:1)
H-band flux ratio of the inner components suggests that either GW Ori B is
undergoing a preferential accretion event that increases its disk luminosity or
that the estimate of the masses has to be revisited in favour of a more equal
mass-ratio system that is seen at lower inclination. Accretion disk models of
GW Ori will need to be completely reconsidered because of this outer companion
C and the unexpected brightness of companion B.Comment: 5 pages, 9 figures, accepted Astronomy and Astrophysics Letters. 201
LLiST - a new star tracker camera for tip-tilt correction at IOTA
The tip-tilt correction system at the Infrared Optical Telescope Array (IOTA)
has been upgraded with a new star tracker camera. The camera features a
backside-illuminated CCD chip offering doubled overall quantum efficiency and a
four times higher system gain compared to the previous system. Tests carried
out to characterize the new system showed a higher system gain with a lower
read-out noise electron level. Shorter read-out cycle times now allow to
compensate tip-tilt fluctuations so that their error imposed on visibility
measurements becomes comparable to, and even smaller than, that of higher-order
aberrations.Comment: To be published in "New Frontiers in Stellar Interferometry", W. A.
Traub, ed., SPIE Proceedings Series, Vol. 5491, paper [5491-126]; 10 pages, 6
figures, 1 table; Latex spie class, uses packages graphicx and url; bib style
spiebib; keywords: interferometry, tip-tilt correctio
Detectability of Terrestrial Planets in Multi-Planet Systems: Preliminary Report
We ask if Earth-like planets (terrestrial mass and habitable-zone orbit) can
be detected in multi-planet systems, using astrometric and radial velocity
observations. We report here the preliminary results of double-blind
calculations designed to answer this question.Comment: 10 pages, 0 figure
Stable Propagation of a Burst Through a One-Dimensional Homogeneous Excitatory Chain Model of Songbird Nucleus HVC
We demonstrate numerically that a brief burst consisting of two to six spikes
can propagate in a stable manner through a one-dimensional homogeneous
feedforward chain of non-bursting neurons with excitatory synaptic connections.
Our results are obtained for two kinds of neuronal models, leaky
integrate-and-fire (LIF) neurons and Hodgkin-Huxley (HH) neurons with five
conductances. Over a range of parameters such as the maximum synaptic
conductance, both kinds of chains are found to have multiple attractors of
propagating bursts, with each attractor being distinguished by the number of
spikes and total duration of the propagating burst. These results make
plausible the hypothesis that sparse precisely-timed sequential bursts observed
in projection neurons of nucleus HVC of a singing zebra finch are intrinsic and
causally related.Comment: 13 pages, 6 figure
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