A intervenção fisioterapêutica em crianças com transtorno do espectro autista: uma revisão de literatura

The main purpose of this study is to address the psychomotor disorders present in ASD and the various possibilities of physiotherapeutic intervention. The main objective of this research is to present the contribution of Physical Therapy to the neuropsychomotor development of children with ASD. In order to concentrate the information that permeates the study's theme, a narrative bibliographic review was carried out, of an exploratory and qualitative nature, which allowed the gathering of research that can point to successful paths based on scientific evidence, mainly related to the contribution of physiotherapy in the psychomotor development of children with Autistic Spectrum Disorder (ASD). The study concluded that articles focused on interventions, especially those aimed at psychomotor development, are still scarce and have low levels of scientific evidence. Despite this, it is possible to conclude that ASD is characterized by a psychomotor disorder that can present itself in different ways, that physiotherapy can contribute to the improvement of the condition of children with ASD and that, regardless of the techniques and approaches used, what will define the success of the intervention is the work in partnership with the family and with a multidisciplinary team and, above all, the connection that the physiotherapist will be able to establish with each of his patients.O presente estudo tem por principal escopo abordar os distúrbios psicomotores presentes em quadros de TEA e as diversas possibilidades de intervenção fisioterapêutica. O objetivo maior desta pesquisa é apresentar a contribuição da Fisioterapia para o desenvolvimento neuropsicomotor de crianças com o TEA. Para concentrar as informações que permeiam a temática do estudo, foi realizada uma revisão bibliográfica narrativa, de caráter exploratório e qualitativo, a qual permitiu a reunião de pesquisas que possam apontar caminhos exitosos baseados em evidências científicas, principalmente relacionadas à contribuição da fisioterapia no desenvolvimento psicomotor de crianças com Transtorno do Espectro Autista (TEA). O estudo concluiu que os artigos voltados para as intervenções, principalmente aquelas que visam o desenvolvimento psicomotor, ainda são escassos e apresentam níveis baixos de evidência científica. Apesar disso, é possível concluir que o TEA tem como característica o distúrbio psicomotor que pode se apresentar de formas variadas, que a fisioterapia pode contribuir para a melhora do quadro de crianças com TEA e que, independentemente das técnicas e abordagens utilizadas, o que definirá o êxito da intervenção é o trabalho em parceria com a família e com uma equipe multiprofissional e, principalmente, a conexão que o fisioterapeuta conseguirá estabelecer com cada um de seus pacientes

Increased interregional virus exchange and nucleotide diversity outline the expansion of chikungunya virus in Brazil

Abstract The emergence and reemergence of mosquito-borne diseases in Brazil such as yellow fever, zika, chikungunya, and dengue have had serious impacts on public health. Concerns have been raised due to the rapid dissemination of the chikungunya virus across the country since its first detection in 2014 in Northeast Brazil. In this work, we carried out on-site training activities in genomic surveillance in partnership with the National Network of Public Health Laboratories that have led to the generation of 422 chikungunya virus genomes from 12 Brazilian states over the past two years (2021–2022), a period that has seen more than 312 thousand chikungunya fever cases reported in the country. These genomes increased the amount of available data and allowed a more comprehensive characterization of the dispersal dynamics of the chikungunya virus East-Central-South-African lineage in Brazil. Tree branching patterns revealed the emergence and expansion of two distinct subclades. Phylogeographic analysis indicated that the northeast region has been the leading hub of virus spread towards other regions. Increased frequency of C > T transitions among the new genomes suggested that host restriction factors from the immune system such as ADAR and AID/APOBEC deaminases might be driving the genetic diversity of the chikungunya virus in Brazil

Resumos concluídos - Bioquímica

Resumos concluídos - Bioquímic

Resumos concluídos - Bioquímica

Resumos concluídos - Bioquímic

Characterisation of microbial attack on archaeological bone

As part of an EU funded project to investigate the factors influencing bone preservation in the archaeological record, more than 250 bones from 41 archaeological sites in five countries spanning four climatic regions were studied for diagenetic alteration. Sites were selected to cover a range of environmental conditions and archaeological contexts. Microscopic and physical (mercury intrusion porosimetry) analyses of these bones revealed that the majority (68%) had suffered microbial attack. Furthermore, significant differences were found between animal and human bone in both the state of preservation and the type of microbial attack present. These differences in preservation might result from differences in early taphonomy of the bones. © 2003 Elsevier Science Ltd. All rights reserved

NEOTROPICAL XENARTHRANS: a data set of occurrence of xenarthran species in the Neotropics

Xenarthrans—anteaters, sloths, and armadillos—have essential functions for ecosystem maintenance, such as insect control and nutrient cycling, playing key roles as ecosystem engineers. Because of habitat loss and fragmentation, hunting pressure, and conflicts with domestic dogs, these species have been threatened locally, regionally, or even across their full distribution ranges. The Neotropics harbor 21 species of armadillos, 10 anteaters, and 6 sloths. Our data set includes the families Chlamyphoridae (13), Dasypodidae (7), Myrmecophagidae (3), Bradypodidae (4), and Megalonychidae (2). We have no occurrence data on Dasypus pilosus (Dasypodidae). Regarding Cyclopedidae, until recently, only one species was recognized, but new genetic studies have revealed that the group is represented by seven species. In this data paper, we compiled a total of 42,528 records of 31 species, represented by occurrence and quantitative data, totaling 24,847 unique georeferenced records. The geographic range is from the southern United States, Mexico, and Caribbean countries at the northern portion of the Neotropics, to the austral distribution in Argentina, Paraguay, Chile, and Uruguay. Regarding anteaters, Myrmecophaga tridactyla has the most records (n = 5,941), and Cyclopes sp. have the fewest (n = 240). The armadillo species with the most data is Dasypus novemcinctus (n = 11,588), and the fewest data are recorded for Calyptophractus retusus (n = 33). With regard to sloth species, Bradypus variegatus has the most records (n = 962), and Bradypus pygmaeus has the fewest (n = 12). Our main objective with Neotropical Xenarthrans is to make occurrence and quantitative data available to facilitate more ecological research, particularly if we integrate the xenarthran data with other data sets of Neotropical Series that will become available very soon (i.e., Neotropical Carnivores, Neotropical Invasive Mammals, and Neotropical Hunters and Dogs). Therefore, studies on trophic cascades, hunting pressure, habitat loss, fragmentation effects, species invasion, and climate change effects will be possible with the Neotropical Xenarthrans data set. Please cite this data paper when using its data in publications. We also request that researchers and teachers inform us of how they are using these data

Núcleos de Ensino da Unesp: artigos 2008

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq