22 research outputs found
Nitric Oxide Not Apoptosis Mediates Differential Killing of Mycobacterium bovis in Bovine Macrophages
- Author
- AK Randhawa
- Alejandro Benítez-Guzmán
- Antonio J. Vallecillo
- C Thoen
- CJ Martin
- DG Pritchard
- DL Clemens
- DP Gil
- E Liebana
- GA Campbell
- H Pan
- Hugo Esquivel-Solís
- IP Fairbairn
- J Feng
- J Keane
- J Keane
- J McNair
- J Piercy
- JA Gutierrez-Pabello
- JE Albina
- JM Pollock
- José A. Gutiérrez-Pabello
- JP Cassidy
- JS Ferguson
- JS Park
- L Bosca
- L. Garry Adams
- M Arias
- M Denis
- M Denis
- M Denis
- M Rojas
- MD Sanchez
- MF Rodrigues
- ML Arcila
- N Kumar
- P Horin
- P Laochumroonvorapong
- R Barthel
- R Barthel
- R Placido
- S Widdison
- Stephen V. Gordon
- T Garnier
- T Qureshi
- TA Paixao
- U Castillo-Velazquez
- UE Schaible
- WR Berrington
- WR Waters
- X Vega-Manriquez
- Yolanda López-Vidal
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2013
- Field of study
To identify the resistance phenotype against Mycobacterium bovis in cattle, we used a bactericidal assay that has been considered a marker of this trait. Three of 24 cows (12.5%) were phenotyped as resistant and 21 as susceptible. Resistance of bovine macrophages (MΦ) to BCG challenge was evaluated for its association with SLC11A1 GT microsatellite polymorphisms within 3′UTR region. Twenty-three cows (95.8%) had a GT(13) genotype, reported as resistant, consequently the SLC11A1polymorphism was not in agreement with our bactericidal assay results. MΦ of cows with resistant or susceptible phenotype were challenged in vitro with virulent M. bovis field strain or BCG, and nitric oxide production, bacterial killing and apoptosis induction were measured in resting and LPS-primed states. M. bovis field strain induced more apoptosis than BCG, although the difference was not significant. Resistant MΦ controlled better the replication of M. bovis (P<0.01), produced more nitric oxide (P<0.05) and were slightly more prone to undergo apoptosis than susceptible cells. LPS pretreatment of MΦ enhanced all the functional parameters analyzed. Inhibition of nitric oxide production with n (G)-monomethyl-L-arginine monoacetate enhanced replication of M. bovis but did not modify apoptosis rates in both resistant and susceptible MΦ. We conclude that nitric oxide production not apoptosis is a major determinant of macrophage resistance to M. bovis infection in cattle and that the influence of SLC11A1 gene 3′UTR polymorphism is not associated with this event
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
- Author
- Abbott TE
- Abdallah RI
- Abdel-Aal IR
- Abdelmonem SA
- Abdo WF
- Abellan AN
- Abellán AN
- Abellán AN
- Abellán AN
- Abrams ST
- Ackerley C
- Acuña M
- Adda M
- Adhikari NK
- Adriano G
- Adrie C
- Affatato R
- Affatato R
- Afonso-Rivero D
- Agarossi A
- Agarwal LK
- Ageeva T
- Agrawal R
- Aguayo-DeHoyos E
- Aguilar AL
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguirregabyria M
- Ahmadnia E
- Ahn C
- Ahn JY
- Ahn JY
- Ahn MY
- Ahn MY
- Aitken LM
- Akalaev R
- Akbarzadeh A
- Akcan-Arikan A
- Akhlagh SH
- Akhtar N
- AKI Research Group
- Akiduki N
- Akin S
- Akizuki N
- Akkoc T
- Ala-Kokko T
- Alanio A
- Albaiceta GM
- Albaladejo P
- Alberto F
- Albuisson E
- Alcala MA
- Alcázar L
- Aldabo-Pallas T
- Aldana NN
- Aldecoa C
- Alegría L
- Alejandro R
- Alejo GC
- Alejos RM
- Alexandrova E
- Algarte R
- Algarte R
- Algieri I
- Algora-Weber A
- Alhamdi Y
- Aliaga FA
- Aliberti S
- Alkan A
- Almudena PM
- Almudevar PM
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- Almudévar PM
- Altıntas ND
- Alvarez J
- Alves SC
- Alzola LM
- Amargianitakis V
- Amaro R
- Amato MB
- Ambler M
- Amerongen MP
- Amininejad T
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- Amorim V
- Anand RK
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- Antón DG
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- Araujo NJ
- Araujo VF
- ARIAM registry of adult cardiac surgery
- ARIAM-ANDALUCIA
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- Arias-Verdu MD
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- CAPCRI Study
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- Christopher KB
- Chrétien JM
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- ENVIN-HELICS Study Group
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- IPREA Study Group
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- Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group
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- Javadpour S
- Jayasinghe S
- Jean-Baptiste S
- Jean-Baptiste S
- Jensen AE
- Jensen JU
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- Jeon YD
- Jeong IY
- Jeong IY
- Jeong WY
- Jeong WY
- Jian Z
- Jiao LR
- Jibaja M
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- Jiménez GJ
- Jo YH
- Joachim J
- Jochmans S
- John G
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- Jonas M
- Jonas M
- Jones C
- Joshi R
- Joshi V
- Jovaisa T
- JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group
- Juan WC
- Juanas CA
- Judickas S
- Juez A
- Juliarena A
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- Jun IG
- Jung K
- Jung KW
- Junior JM
- Kaczirek K
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- Kalenka A
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- Kamali E
- Kaminsky GE
- Kaneko M
- Kang M
- Kang M
- Kang PL
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- Kang PL
- Kang Y
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- Kara A
- Karachi F
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- Karsten E
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- Kashiya S
- Kashyap R
- Katabami K
- Katabami K
- Katabami K
- Katabami K
- Katira BH
- Kavanagh BP
- Kawamura N
- Kawano S
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- Kayaaslan B
- Kayambu G
- Kazutoshi F
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- Ke MW
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- Kellner F
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- Kenardy J
- Keough E
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- Kerr C
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- Khadjibaev A
- Khaliq W
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- Kim DJ
- Kim HJ
- Kim JM
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- Kim KS
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- Kim KS
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- Kim MH
- Kim MH
- Kim W
- Kimmoun A
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- Kinnear J
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- Kirakli C
- Kirca H
- Kirman M
- Kirwan CJ
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- Klaus DA
- Kleinpell R
- Kluge S
- Knafelj R
- Knight LD
- Ko JI
- Ko SB
- Kobayashi A
- Koco E
- Kodate A
- Kodate A
- Kodate A
- Kokkini S
- Kolnikova I
- Komuro T
- Kondili E
- Kongpolprom N
- Kooner G
- Kostalas M
- Kosuk ME
- Kotsopoulos A
- Kou PS
- Kouatchet A
- Kovacikova L
- Kox M
- Kraegpoeth A
- Krenn CG
- Krishna B
- Kristof J
- Kruger A
- Kruger A
- Krüger A
- Ku NS
- Ku NS
- Kubik M
- Kubota K
- Kuebler WM
- Kulaga EV
- Kulkarni AP
- Kumari BK
- Kumbamu A
- Kunze-Szikszay N
- Kurmukov IA
- Kurth T
- Kurtz P
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- Kwon HM
- Kwon HM
- Kwon WY
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- Kye YC
- Kyle UG
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- Labaune MA
- Labra C
- Lacerda P
- Laerkner E
- Lafaurie M
- Lafuente E
- Lagonidis D
- Lagos R
- Lahmer T
- Lai CC
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- Latini R
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- Latini R
- Latorre J
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- Laureys S
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- Legrand M
- Legrand M
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- Leite RT
- Leonard H
- Leone M
- Leone M
- Lerma FA
- Lesmes SP
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- Letizia T
- Levrat Q
- Levy B
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- León JP
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- Li R
- Li SH
- Liao X
- Lichtenstein D
- Lim TH
- Limuti R
- Lin KC
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- Lin WC
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- Lipcsey M
- Lischinsky A
- Lissonde F
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- Litchfield K
- Liu CP
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- Liu D
- Llaurado-Serra M
- Llorente B
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- Lobato MS
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- Loizou C
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- Longhi L
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- Lortat-Jacob B
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- Ly H
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- Macfarlane B
- MacKay A
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- Mackey G
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- Macrì M
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- Maekawa K
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- Maggiorini M
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- Magnanimi E
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- Mezidi M
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- Mimoz O
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- Miranda F
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- Mistry M
- Mistry N
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- Mitchell S
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- Olaechea P
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- Savi C
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- Stocchetti N
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- Stretti F
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- Sánchez MJ
- Sánchez MJ
- Sánchez MJ
- Sánchez MJ
- Sánchez PC
- Sánchez PC
- Sánchez-Elvira LA
- Tabatabaei HR
- Tabei SH
- Taccone F
- Taccone FS
- Taccone FS
- Taccone FS
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- Taccone FS
- Taccone FS
- Taccone FS
- Taggu A
- Taggu A
- Takahashi H
- Takaki S
- Takaki S
- Takeda M
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- Takei T
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- Tanaka H
- Tanaka S
- Tanaka S
- Tane N
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- Tapponnier R
- Tapponnier R
- Tapponnier R
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- Tavazzi G
- Tavazzi G
- Teboul JL
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- Tena SA
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- Thabut G
- Theodorakopoulou M
- Thies P
- Thilakasiri MC
- Thomas B
- Thompson E
- Thévenin D
- Tiainen M
- Timsit JF
- Tirkkonen J
- Tirumala S
- Tjepkema-Cloostermans MC
- Tobar M
- Tofiño AL
- Toh CH
- Tokyo Womens Medical University
- Tomas E
- Tomas E
- Tomic I
- Tominaga N
- Tomás MA
- Tonelotto BF
- Tonetti T
- Tonetti T
- Topcu L
- Tormos P
- Torner MM
- Torner MM
- Torrance HD
- Torrent RL
- Torrent RL
- Torres A
- Torres E
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- Torriglia F
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- Tosi F
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- Vallverdu M
- Vallverdu M
- Vallverdú I
- Vallés J
- van den Boogaard M
- van der Heiden ES
- van der Hoeven JG
- van der Hoeven JG
- van der Voort PH
- van Galen T
- van Ieperen SN
- Van Logten T
- van Nes M
- van Putten MJ
- van Thiel RJ
- van Wijk A
- Vandijck D
- Vaneker I
- Vanhuyse F
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- Vaquerizo C
- Varas GM
- Varas JL
- Varea MM
- Vargiolu A
- Varma A
- Varpula T
- Vatsik MV
- Vazquez D
- Vedage D
- Vega LM
- Veigas P
- Vela JL
- Velasquez T
- Venkatesan K
- Venn R
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- Venot M
- Venrdramin A
- Ventura-Rosado A
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- Viciana R
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- Vidal MV
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- Vieillard-Baron A
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- Viera MA
- Viera MA
- Vigne C
- Villa G
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- Villalba D
- Villamizar PR
- Villamizar PR
- Villanova M
- Villard I
- Villarreal E
- Villarreal E
- Vincent B
- Vincent JL
- Vincent JL
- Vincent JL
- Vincent JL
- Vincent JL
- Vincent JL
- Vincent JL
- Vinje LJ
- Vinsonneau C
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- Vittone F
- Vogelaers D
- Voiriot G
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- Wang H
- Wann SR
- Wann SR
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- Wathanawatthu T
- Wee S
- Welte T
- Welters I
- Wetz A
- Weyer CM
- White C
- Wiesner O
- Wijayatilake DS
- Wildenberg L
- Wilks M
- Wilson ME
- WIND study group
- WIND study group
- WIND study group
- Winder-Rhodes S
- Witter T
- Wolf M
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- Yamaguchi O
- Yamaguchi Y
- Yamaguchi Y
- Yamamoto H
- Yamamoto N
- Yaman G
- Yamashita K
- Yamazaki A
- Yan WW
- Yan WW
- Yang JH
- Yang JS
- Yang YL
- Yasuda H
- Yatabe T
- Yebenes JC
- Yeh YC
- Yemets H
- Yergaliyeva A
- Yılmaz G
- Yilmazer F
- Yodice P
- Yokoyama M
- Yonis H
- Yonis H
- Yonis H
- Yoon SZ
- Yoruk F
- Yoshida K
- Yoshida T
- Yoshida T
- Yoshida T
- Yoshida T
- Yoshihiro S
- Yoshitake E
- You KM
- Youn AM
- Young A
- Yu KM
- Yumoto T
- Yuzawa J
- Yuzawa J
- Zabaletta WJ
- Zabini D
- Zahorec M
- Zaien I
- Zakynthinos S
- Zanello M
- Zani D
- Zarantonello F
- Zayas B
- Zepeda EM
- Zeroual N
- Zerva L
- Zhang J
- Zhou JC
- Zhou JC
- Zhou JX
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- Zibandah N
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- Zwaag J
- Zýková I
- Álvarez JT
- Álvarez-Lerma F
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Meeting abstrac
Evaluation of appendicitis risk prediction models in adults with suspected appendicitis
- Author
- Abbas Sh
- Abbas Sh
- Abbassi Oa
- Abbott T
- Abdelgadir Am
- Abdelrahman A
- Abdelrahman M
- Abdelrahman M
- Abdelwahed A
- Abellan M
- Abellán Am
- Abellán Am
- Abulafi M
- Acharya A
- Acosta A
- Adam Me
- Adams Re
- Adegbola So
- Adegbola So
- Adimonye A
- Adnan M
- Afshar S
- Agresta F
- Agua Ia
- Aguayo Jl
- Agudo Ar
- Ahad A
- Ahel J
- Ahern Dp
- Ahmad A
- Ahmed B
- Ahmed G
- Ahmed Os
- Ahmed Os
- Ahmed S
- Ainsworth P
- Ais G
- Ais G
- Aisoni F
- Akbari K
- Akhtar K
- Akinsola O
- Akram F
- Al-Faham Z
- Al-Khafaji N
- Al-Khyatt W
- Al-Musawi S
- Al-Sarireh B
- Al-Sheikh M
- Alagna V
- Alani M
- Alberca-Paramo A
- Aldrey I
- Alexander R
- Alhammali T
- Alhammali T
- Ali M
- Aljorfi A
- Allen M
- Allington J
- Alonzo A
- Alshafei A
- Altomare Ma
- Alvarez Cm
- Alvarez E
- Alvarez-Gallego M
- Amaducci E
- Amarasinghe R
- Amayo A
- Ambrona-Zafra D
- Amin V
- Ammendola M
- Amtul N
- Amtul N
- Amuthalingam T
- Anandan L
- Anania G
- Anania M
- Anderson Dj
- Anderson O
- Andolfi E
- Andreani Sm
- Andreani Sm
- Andrews B
- Ang A
- Ang A
- Angelieri D
- Angelini M
- Angrisani M
- Anguita F
- Ansaloni L
- Ansari A
- Aravind B
- Archer Je
- Arcuri Ga
- Arcuri Ga
- Aremu Ma
- Arenal-Vera Jj
- Aresu S
- Aresu S
- Argenio G
- Argenti F
- Armellini A
- Arnau M
- Arredondo J
- Arroyo A
- Arshad F
- Arunachalam S
- Arunachalam S
- Arunachalam S
- Aruparayil N
- Asensio-Gomez L
- Ashmore Dl
- Ashmore Dl
- Ashour O
- Ashraf N
- Asmadi Aa
- Assaf N
- Assaf N
- Assaf N
- Athersmith Mj
- Atzeni J
- Avalapati H
- Avanzolini A
- Avanzolini A
- Awokoya Oo
- Ayllón-Gámez S
- Ayube-Brown J
- Azabdaftari A
- Azevedo J
- Azevedo Jm
- Baddams Ts
- Badenoch T
- Badii B
- Badran A
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- Bagga R
- Baginski A
- Bailey Ja
- Bailey S
- Bailey S
- Bailon-Cuadrado M
- Baird C
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- Balasubramaniam A
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- Ball A
- Ball A.
- Ballabio M
- Ballester Mm
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- Banks A
- Bansal H
- Baraghini M
- Barbosa L
- Barker T
- Barker T
- Barnieh W
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- Baronio G
- Barrie A
- Barter Ca
- Bartoli A
- Bascuas-Rodrigo B
- Baseggio M
- Bastianpillai J
- Bawa S
- Baz-Figueroa C
- Bazán-Hinojo Mc
- Bazán-Hinojo Mc
- Beasley Wd
- Bedoya S
- Beggs A
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- Bellochi R
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- Beltran-De-Heredia J
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- Berti S
- Bevan Ke
- Bevan V
- Beverstock A
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- Bhanderi S
- Bhanderi S
- Bhanderi S
- Bhanderi S.
- Bhangu A. Nepogodiev D
- Bhangu A
- Bhangu A
- Bhangu A
- Bhangu A
- Bhargava A
- Biancafarina A
- Biancafarina A
- Bianchi Cl
- Bianchi Cl
- Bianco A
- Bilku D
- Birindelli A
- Birindelli A
- Birindelli A
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- Blackwell J
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- Blencowe Ns
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- Boereboom C
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- Bolger Jc
- Bolton W
- Bolzon S
- Bond S
- Bond-Smith G
- Bondurri A
- Bonfante P
- Bonomo M
- Borg Cm
- Borges Fc
- Borghi F
- Borghol K
- Boshier Pr
- Botelho P
- Bowen J
- Bowerman H
- Bowley D
- Bowman Cr
- Bowman Cr
- Boyd-Carson H
- Boza K
- Bradshaw Cj
- Branagan G
- Bravo-Gutiérrez Af
- Bravo-Gutiérrez Af
- Brennan S
- Brett M
- Brewer H
- Brewer Hk
- Brewer Hk
- Brews R
- Brien Jo
- Bronder C
- Brown A
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- Brown Ce
- Brown Ce
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- Brown M
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- Brown R
- Bruce Js
- Brunelli Db
- Bryan Es
- Buckley-Jones S
- Bukhari W
- Bull C
- Bullivant Jk
- Burke J
- Burns Km
- Burnside D
- Busuttil A
- Byrne Be
- Byrnes Ck
- Caballero A
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- Callan R
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- Calvo H
- Calvo M
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- Carrano Fm
- Carrano Fm
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- Carvalho Lc
- Carvalho N
- Casimiro C
- Castagnoli G
- Castagnoli G
- Caula C
- Caula C
- Cavallo D
- Cavero A
- Cay P
- Ceccarelli G
- Cerdán-Santacruz C
- Cerdán-Santacruz C
- Cerdán-Santacruz C
- Cerdán-Santacruz C
- Cervellera M
- Cesari Mc
- Chalk A
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- Chapman Sj
- Chapple Ks
- Charalabopoulos A
- Charalambous Mp
- Chasty B
- Chatzikonstantinou M
- Chatzikonstantinou M
- Chauhan P
- Chauhan P
- Chauhan P.
- Cheah Wl
- Chean Cs
- Chean Cs
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- Cheng Sa
- Cheruvu M
- Chessa A
- Chessa A
- Chetta G
- Chetta N
- Chianese G
- Chillitupa Cz
- Chimetto A
- Chin My
- Chishti Ia
- Chitsabesan P
- Chng S
- Choi S
- Chok Sm
- Chok Sm
- Chong B
- Choolani-Bhojwani E
- Choong Jh
- Choong Jh
- Choong Jh
- Chowdhary M
- Chowdhury F
- Chowdhury F
- Choy Ch
- Choy Ch
- Chrastek D
- Christian L
- Christides A
- Christopoulos P
- Chudek D
- Chui K
- Cianchi F
- Cidoncha A
- Cillara N
- Cillara N
- Cillara N
- Cipparrone M
- Cirillo B
- Clark Gl
- Clark S
- Clement Kd
- Clement Kd
- Clements B
- Clements C
- Clements J
- Clements J.
- Clements Ja
- Clements Jd
- Clements Jm
- Clements Jm
- Clements Js
- Clerici F
- Clingan R
- Cloney L
- Clough E
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- Coccolini F
- Cocorullo G
- Coe Po
- Cohen Ja
- Colangelo E
- Coletta D
- Coletta D
- Coletti M
- Collado-Roura F
- Collier-Wakefield O
- Colombo F
- Colombo F
- Colvin Da
- Colvin Da
- Compagnoni B
- Conci S
- Connelly Tm
- Connor Kl
- Connor Kl
- Connor Mj
- Connor Mj
- Conti D
- Contine Ac
- Contreras Rg
- Contreras-Saiz E
- Cook V
- Cooke F
- Coppola M
- Coratti F
- Corbellini C
- Cordoba E
- Cordoba E
- Cormenzana Ob
- Correia D
- Correia J
- Cortés Gv
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- Cossu F
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- Costamagna D
- Cotton Ae
- Couch Dg
- Cousins L
- Couso Jr
- Cox M
- Coyle D
- Creasy W
- Cremades P
- Criado Adc
- Crone A
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- Cruickshank N
- Cuadrado Mm
- Cucinotta E
- Cuello-Guzmán E
- Cunha P
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- Curti R
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- Curtis-Martínez C
- Cynthia G
- Cánovas-Moreno G
- D'Ambra L
- D'Amico Fe
- D'Amico Fe
- D'Amico Fe
- D'Auria M
- D'Auria M
- D'Souza N
- Daga O
- Dalmia S
- Dandy R
- Daniels I
- Danquah-Boateng D
- Dar Fa
- Dar Fa
- Dart K
- Das A
- Daureeawoo R
- Davidson Jr
- Davidson S
- Davies Pl
- Davis S
- De Andres U
- De Burgos Cb
- De Chaves-Rodríguez Pg
- De Freitas S
- De Luca E
- De Marchi F
- De Marco P
- De Nardi P
- De Nardi P
- De Nisco C
- De Padua C
- De Prizio M
- De-La-Herranz-Guerrero P
- De-Manzoni-Garberini A
- De-Manzoni-Garberini A
- De-Manzoni-Garberini A
- De-Marchi Ja
- De-Marchi Ja
- De-Soto-Cardenal B
- Dean Ea
- Dean S
- Del Basso C
- Del Pozo E
- Del-Valle-Ruiz Sr
- Delgado-Plasencia Lj
- Delimpalta C
- Delimpalta C
- Delogu D
- Denley S
- Dennison G
- Depalma N
- Deserra A
- Desiderio J
- Devezas V
- Devine Aa
- Dhar M
- Dharamavaram S
- Dhari Aa
- Dhesi S
- Di Cintio A
- Di Franco F
- Di Gioia P
- Di Saverio S
- Di Zitti L
- Diaz A
- Dickson Ea
- Divekar Ga
- Dixon F
- Dobbs S
- Dobson C
- Docherty Ja
- Doherty C
- Dominguez-Sanchez C
- Donaldson G
- Donaldson G
- Donohoe No
- Donohoe No
- Douka E
- Doulias T
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- Doyle C
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- Drake Tm
- Drye N
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- Dujovne P
- Dunning Pg
- Duran-Muñoz-Cruzado Vm.
- Durbacz M
- Dyal A
- Dyson S
- Díaz-Vico T
- Eardley Nj
- Earnshaw L
- Easdon S
- Ebied H
- Echazarreta E
- Edwards Se
- Egan Rj
- Egan Rj
- Eguaras I
- Eiben I
- Eiben Ie
- Eiben P
- El-Masry S
- El-Tayar O
- El-Tayar O
- Elbetti C
- Elgaddal S
- Elia M
- Ellis B
- Elseedawy M
- Elshaer M
- Elshaer M
- Emslie Km
- Engall N
- Engall N
- Engall N
- English Wj
- Ercolani G
- Erdas E
- Erdas E
- Eretta Co
- Escoll-Rufino J
- Escuder J
- Esmail Hd
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- Espin-Basany E
- Espina B
- Espinosa J
- Esteves Mb
- Ettles C
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- Evans Jd
- Everden A
- Evoli Le
- Ezerska E
- Fadel M
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- Fairfield Cj
- Falaschi F
- Falco N
- Fanibi Bf
- Fareleira A
- Farhan-Alanie M
- Farina V
- Faris Ar
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- Farrow Ez
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- Fasuyi Ja
- Faulkner G
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- Feleppa C
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- Fermiñán A
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- Fernández-Candela A
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- Fernández-Martínez D
- Fernández-Martínez D
- Feroci F
- Ferrara F
- Ferrara F
- Ferreira Js
- Ferreira Ms
- Ferrer-Vilela I
- Fijo Lm
- Finch Jg
- Finlayson H
- Finotti E
- Fiore L
- Fiorot A
- Flack T
- Fleming Ta
- Fleres F
- Foers W
- Foley Nm
- Foley Nm
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- Fontana T
- Fontani A
- Fooks P
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- Forouzanfar A
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- Gaines E
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- Gallo G
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- García-Carrero M
- García-Catalá L
- García-Catalá L
- García-Granero A
- García-Granero A
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- García-Novoa A
- García-Novoa A
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- García-Rivera Co
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- Ghatorae S
- Ghazala R
- Ghazanfar Ma
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- Giraudo G
- Giubilo C
- Giudicissi R
- Giuffrida Mc
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- Gjoni E
- Gjoni E
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- Glasbey Jc
- Glasbey Jc
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- Golda T
- Golder Am
- Golder Am
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- Goldin E
- Gomes Ap
- Gomez Cj
- Gomez-Carmona Z
- Gomez-Facundo H
- Gomez-Rosado Jc
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- González-Nicolás T
- Gonzálvez-Guardiola P
- Gonçalves D
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- Gopinath S
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- Gormely R
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- Gosal A
- Govind G
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- Grandi S
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- Graveston J
- Graveston J
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- Griffith Jp
- Griffiths E
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- Griffiths Np
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- Griggs R
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- Groppo G
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- Pata F
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- Xidas A
- Yalamarthi S
- Yang P
- Yanni F
- Yardimci E
- Yasin T
- Yen Sk
- Yeung K
- Yeung K
- Yoganathan S
- Yoong S
- Youssef H
- Yow L
- Yow L
- Zaborowski A
- Zadi Az
- Zalla T
- Zarka Za
- Zarka Za
- Zarog Ma
- Zelazek M
- Zerpa C
- Zhang Ay
- Zhou S
- Zorrilla L
- Zuin M
- Zurleni Tz
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2019
- Field of study
Background
Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis.
Methods
A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis).
Results
Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent).
Conclusion
Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
- Author
- Abad-Motos Ane
- Abbas Ahmed M.
- Abbas Mostafa
- Abbasi Mujeeb
- Abbott Tom
- Abd Karim Muhammad Fairuz Shah
- Abdalaal Ibrahim
- Abdel-Galil Khalid
- Abdelemam Rania
- Abdelgawad Abdalrahman
- Abdelkarim Maryam
- Abdelkhalek Mohamed
- Abdelmageed Abdelfatah
- Abdelmawgoud Sherif
- Abdelmohsen Sarah
- Abdelrahman Ahmed Saber
- Abdelrahman Mostafa
- Abdelwahab Khaled
- Abdou Hossam
- Abdulai Darling Ramatu
- Abdulkhaleq Marwa
- Abdullah Bahiyah
- Abdulsalam Khalifa
- Abdulsalam Shuaib
- Abdur-Rahman Lukman
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abebrese John Tabiri
- Abeldaño Ariel
- Abou-Khalil Jad
- Abou-Taleb Hisham
- Abozid Anwaar
- Abozied Hesham
- Abrate Alberto
- Abu-Zaid Ahmed
- Abubakar Mohammed Kabir
- Abud Burçin
- Abuzaid Mohammed
- Adam Albushra Altayeb
- Adamina Michel
- Adamou Harissou
- Adamu Auwal
- Adamu Kabir Musa
- Adanu Kekeli
- Adebara Idowu
- Adebola Oluwaseyi
- Ademuyiwa Adesoji
- Adeniran Abiodun
- Adepiti Akinfolarin
- Aderogba Adeleke Akeem
- Adesunkanmi Abdulhafiz
- Adeyeye Ademola
- Adisa Adewale
- Adjeso Theophilus Justus Kofi
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adu-Aryee Nii Armah
- Adumah Collins
- Afzal Irrum
- Agapov Mikhail
- Agarwal Gaurav
- Agarwal Ravi
- Agbeko Anita Eseenam
- Agbeno Evans Kofi
- Agbonrofo Peter
- Agboola Oluseyi
- Aggarwal Gaurav
- Aghadi Ifeanyi
- Aghtarafi Natasha
- Agrawal Amit
- Agresta Ferdinando
- Aguado Héctor J.
- Aguilera-Arevalo Maria-Lorena
- Aherne Thomas
- Ahmad Aline
- Ahmad Maleeha
- Ahmad Misbahu
- Ahmad Sarwat
- Ahmad Shahzaib
- Ahmad Shoaib
- Ahmed Hayat Tarig Abdelhafiz
- Ahmed Khalid
- Ahmed Sharwany
- Ahmed Shima
- Ahmed Usama
- Aisuodionoe-Shadrach Oseremen
- Aitken Sarah
- Ajenifuja Kayode
- Ajiya Abdulrazak
- Akeel Nouf
- Akin Emrah
- Akinajo Opeyemi
- Akinyemi Tosin
- Akrida Ioanna
- Aktokmakyan Talar Vartanoglu
- Akwaisah Ayoub
- Al Bettar Osama
- Al-Badawi Ismail A.
- Al-Juaifari Maytham
- Al-Khyatt Waleed
- Al-Mallah Abdullah
- Al-Nusairi Ahmed
- Al-Saadi Nina
- Al-Sayaghi Khaled
- Al-Shaiji Tariq
- Al-Shehari Mohammed
- Al-Touny Aiman
- Al-Touny Shimaa A.
- Aladawi Omar
- Aladna Abdallah
- Alali Mahmoud
- Alam Mahmood
- Alam Mohammed Shadrul
- Alarabi Rehab
- Alawneh Yazan
- Alayande Barnabas
- Albanese Erminia
- Albayadi Eslam
- Albdour Maram
- Alconchel Felipe
- Alderazi Amer
- Alegbeleye Bamidele
- Alekberli Tural
- Alemu Misganaw Alemu Adimass
- Alexander Philip
- Alfieri Alex
- Algahtany Khaled
- Algarni Kamal
- Alhamad Ameen
- Alhamid Mohammad
- Alharmi Rawan A. Rahman
- Alharthi Mohammed
- Alhazmi Barrag
- Ali Mohamed Shafi Mahboob
- Ali Stephen
- Alibrahim Hidar
- Aljaaly Hattan
- Aljaiuossi Anas
- Aljanadi Firas
- Aljiffry Murad
- Aljirdabi Noof
- Alkahlan Mohammed
- Alkhalifa Elmustafa
- Alkhatib Sondos
- Alkhatieb Maram
- Allan Anna
- Almarshad Felwa
- Almgla Naser
- Almhimid Ali
- Almiqlash Bushray
- Almoshantaf Mohammad Badr
- Almutairi Abdulmjeed
- Alnsour Abed Alfattah Mahmoud
- Alobied Majd
- Alomar Osama
- Alonso Jesús Aarón Martínez
- Alonso Manuel Diez
- Alonso Nestor Fabian Pedraza
- Alonso Veronica
- Alqallaf Abdullah
- Alqaseer Asma
- Alrayes Bourhan
- Alsefri Maryam
- Alser Osaid
- Alsharif Mohammed
- Alsori Mohamed
- Altaf Abdulmalik
- Altinel Yuksel
- Altiner Saygin
- Altouny Ahmad
- Altun Demet
- Alvarez Natalia
- Alvarez-Lozada Luis Adrian
- Alvi Abdul
- Alwael Athari
- Alwash Mohammed
- Alyami Ziyad
- Alyousef Mohammed
- Alzahrani Saud
- Alzerwi Nasser
- Amin Shivang
- Amir Mohammed
- Ammar Ahmed Siddique
- Ammendola Michele
- Amores Remedios Revilla
- Amrayev Sultan
- Anastasiadou Sofia
- Ancans Guntis
- Anderson Caroline
- Andreani Lorenzo
- Andreotti Dario
- Andreuccetti Jacopo
- Andrianakis Alexandros
- Andro Christophe
- Anesi Alexandre
- Angamuthu Stephen
- Angeles Martina Aida
- Angelico Roberta
- Angelis Fragkiskos
- Angelou Dimitrios
- Angelou Kyveli
- Angulo Victor Pinto
- Anjum Arfa
- Anjum Muhammad Ayyub
- Annicchiarico Alfredo
- Anoldo Pietro
- Ansaloni Luca
- Anthoulakis Christos
- Antonelli Amedeo
- Anwar Mohamed
- Anwar Sumadi Lukman
- Anwer Mariyah
- Anyanwu Lofty-John
- Apostolou Christos
- Apostolou Konstantinos
- Appiah-Kubi Adu
- Aprea Giovanni
- Arbab Hana
- Archer James
- Ardura Francisco
- Aremu Muyiwa
- Arif Tahera
- Arkani Samara
- Armatura Giulia
- Armijos Daniel
- Arnaout Ali
- Arnaoutoglou Eleni
- Arnaud Alexis P.
- Arneja Jugpal
- Arrangoiz Rodrigo
- Arshad Muhammad
- Arthur Joshua
- Ashcroft James
- Ashford Bruce
- Ashraf Fariha
- Asiimwe Daniel
- Asirifi Samuel Amoako
- Asla Amir
- Aslam Ramisha
- Aspide Raffaele
- Ataya Karim
- Ateca Ibabe Villalabeitia
- Atici Semra Demirli
- Atis Gokhan
- Atkins William
- Atkinson Kate
- Attwood Joseph
- Auerkari Aino
- Augestad Knut Magne
- Augustin Goran
- Aujayeb Avinash
- Avella Pasquale
- Awad Ahmed K.
- Awad Hadeel
- Awad Rabih
- Awad Selmy
- Ayad Kusay
- Ayana Birhanu
- Aydin Yener
- Ayeni Funbi
- Aytac Erman
- Azab Ahmed
- Azami Rizwan
- Azize Diallo Abdoul
- Azzam Ahmed Y.
- Azzis Olivier
- Baba Yabasin Iddrisu
- Babis George
- Bacalbasa Nicolae
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- Badran Saif
- Baduell Albert
- Baeesa Saleh
- Baertschiger Reto
- Bafaquh Mohammed
- Bahassan Omar Mohammed
- Bahrami-Hessari Michael
- Baia Marco
- Baidoo Ebikela Ivie
- Bailey Karen
- Baili Efstratia
- Bains Lovenish
- Baiocchi Gian Luca
- Baiocchi Glauco
- Baiyewu Lateef Ayodele
- Bajaj Ankur
- Bajunaid Khalid
- Balagobi Balasingam
- Balasubramanian Ishwarya
- Balduzzi Alberto
- Baldwin Alexander
- Balla Andrea
- Balogh Zsolt J.
- Balogun James A.
- Balogun Simon
- Baloyiannis Ioannis
- Ban Vin Shen
- Bandyopadhyay Samik Kumar
- Bandyopadhyay Soham
- Banerjee Sumit
- Banipal Gurpreet Singh
- Banky Balazs
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- Barranquero Alberto G.
- Barugola Giuliano
- Basendowah Mohammed
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- Bharathan Rasiah
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- Bilfaqirah Majed
- Biloslavo Alan
- Bin Alhassan Baba Alhaji
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- Bissacco Daniele
- BİŞGİN TAYFUN
- Blair James
- Blanco Jose
- Blencowe Natalie
- Bloemers Frank
- Board Timothy
- Bobak Peter
- Boccalatte Luis
- Boedo Maria Jesus Maroño
- Bohmer Rob
- Boira Mar Achalandabaso
- Boisson Matthieu
- Boligo Sofia
- Bolton William
- Bombardini Cristina
- Bonavina Luigi
- Bonci Eduard-Alexandru
- Bondurri Andrea
- Bonilla Antonio Ramos
- Bonsaana Gilbert Batieka
- Booth L.
- Borg Elaine
- Borges Miguel Fróis
- Borges Nuno
- Bork Ulrich
- Borselle Dominika
- Bortul Marina
- Botelho Pedro
- Bottari Andrea
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- Bouliaris Konstantinos
- Bowan Antoinette Bediako
- Bowen Joel
- Bozbiyik Osman
- Bracale Umberto
- Brachini Gioia
- Bramis Konstantinos
- Branagan Graham
- Branzan Daniela
- Brasset Camille
- Bratus Dejan
- Bravo Ana Maria Minaya
- Bravo Sybil Lizanne
- Bright Tim
- Brisinda Giuseppe
- Brodkin Edgar
- Broglia Alessandro
- Brolese Alberto
- Browning Rebecca
- Bruzzaniti Placido
- Brzeszczyński Filip
- Bsisu Isam
- Bua Emmanuel
- Budd Gabrielle
- Bukhari Syed Imran
- Bulian Dirk Rolf
- Bumbasirevic Uros
- Bumber Boris
- Burgos-Blasco Barbara
- Burlov Nikita
- Bussu Francesco
- Bàmbina Fabrizio
- Börner Nikolaus
- Böttcher Arne
- Cabeza Leticia
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- Calabretto Francesca
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- Campuzano Nicolas
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- Capobianco Mattia
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- Capozzi Enrico
- Cappuccio Micaela
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- Carretero Manuel Moriche
- Caruana Edward J.
- Carvello Michele
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- Castaldi Antonio
- Castaño Mario
- Castaño-Leon Ana M.
- Castillo Dayan Fanery Campino
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- Colombari Renan Carlo
- Colombo Francesco
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- Cross George W. V.
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- Cunningham Brian
- Currò Giuseppe
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- Cutmore Carina
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- D'Acapito Fabrizio
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- Davidescu Mihnea
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- Davies Mark
- Davies Richard Justin
- Davis Amelia
- Dawson Amanda Caroline
- Dawson Jonathon
- Dbouk Samer
- De Alarcón Jaime Rodríguez
- De Andrés-Asenjo Beatriz
- De Bacco Marangon Gustavo
- De Campos Prado Caio Antonio
- De Cillia Michael
- De Haro Jorge Irene
- De Haro Joaquin
- De Jesus Labrador Hernandez Gregorio
- De La Infiesta García Carlos
- De La Medina Antonio Ramos
- De La Rosa-Estadella Marta
- De Nardi Paola
- De Oliveira Gabriel Paiva
- De Pastena Matteo
- De Simone Veronica
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- Demetriades Andreas K
- Demetriou Charis
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- Des Déserts Marc Danguy
- Desai Chaitya
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- Dincer Müserref Beril
- Dindyal Shiva
- Djama Zakarya
- Djedovic Gabriel
- Doerner Johannes
- Doherty Daniel
- Dolci Giampiero
- Domanin Maurizio
- Domingo Marta María Arroyo
- Dominguez-Rosado Ismael
- Don Cristine Pathirannehalage
- Donkin Ian
- Donmez Emin Erhan
- Donoghue Sophie
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- Dragisic Vedran
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- Dzhumabaev Khasan
- Dziakova Jana
- Dzogbefia Mawutor
- Díaz Jeancarlos Trujillo
- Dölker Theresa
- Eardley Nicola
- Ebrahim Abdulla
- Echieh Chidiebere Peter
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- Efetov Sergey
- Efremov Sergey
- Egan Richard
- Eiras Miguel Angel Freiria
- Eisa Elamin
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- Ekwen Gerald
- Ekwunife Okechukwu Hyginus
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- Elagili Ahmed
- Elahi Zain
- Elbadawy Merihan A.
- Elbahnasawy Mohamed
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- Elboraei Rahma
- Eldabaa Mohamed
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- Elfeki Hossam
- Elfiky Mahmoud
- Elgazar Amr
- Elghadban Hosam
- Elhadi Muhammed
- Elhassan Wael Atif Fadl
- Elkazaz Ahmed
- Ellafi Amera Ali Dakheel
- Elliot R.
- Elnour Moheyaldien Ahmed Elamin
- Elsadek Menan
- Elsahli Saifaleslam
- Elsalhawy Shady
- Elsayem Karam
- Elshahawy Mahmoud Abdelaziz Mohamed
- Elsherbiny Ahmed
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- Emara Moataz Maher
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- Ezeanochie Michael
- Ezeme Constantine
- Ezenwa Ekene
- Ezomike Uchechukwu
- Fadalla Tarig
- Fadel Zahir T
- Fahim Margo Medhat Fouad
- Fahmy Ali
- Faiz Javaria
- Fajardo Rafael Torres
- Fakhradiyev Ildar
- Fallah Jean-Michel
- Familiari Pietro
- Fang Clarissa Ern Hui
- Faponle Folayemi
- Farhan-Alanie Muhamed
- Farid Shahzaib
- Farooq Muhammad
- Fatima Mishal
- Fayad Elsayed A.
- Federer Simon
- Federico Nicoletta Sveva Pipitone
- Feeney Kaylem
- Fehervari Matyas
- Fekaj Enver
- Fernandez Laura Gomez
- Fernández Julio Domenech
- Ferracci Federica
- Ferrara Francesco
- Ferrari Davide
- Ferrario Luca
- Ferreli Fabio
- Ferrer Antonio Perez
- Ferrer Ursula María Jariod
- Festa Bianca Maria
- Fiacchini Giacomo
- Figus Andrea
- Filipescu Daniela
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- Fiorelli Silvia
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- Fleres Francesco
- Flis Vojko
- Flores S.L.
- Florian Ioan-Alexandru
- Flumignan Carolina Dutra Queiroz
- Flumignan Ronald
- Flórez Luis Joaquín García
- Foessleitner Philipp
- Fontalis Andreas
- Forde Cillian
- Forneris Agustin Albani
- Fortuna Laura
- Fowler George
- Fozo Khaldoun
- Fragoso Marta
- Franceschini Gianluca
- Frankel Adam
- Fransvea Pietro
- Franza Mara
- Fraser Sheila
- Frasson Matteo
- Frisoni Tommaso
- Frolova Yulia
- Frontali Alice
- Frountzas Maximos
- Fruscio Robert
- Fujimoto Yuki
- Furey Joseph
- Fusario Daniele
- Fusini Federico
- Futaba Kaori
- Függer Reinhold
- Gabr Abdullah
- Gada Parth
- Gadelkareem Rabea
- Gafsi Besma
- Gahlot Nitesh
- Gahwagi Milad
- Gaino Francesca
- Galandarov Vagif
- Galandarova Aysuna
- Gallagher Brendan
- Galliard Katherine
- Gallo Oreste
- Galvan Armando
- Gananadha Sivakumar
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- Glass Nina
- Glowka Tim R.
- Gmati Aimen
- Goel Neha
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- Katechia Devvrat
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- Katsaros Ioannis
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- Katsura Morihiro
- Kauppila Joonas H
- Kaur Amanjot
- Kausar Nabila
- Kavalakat Alfie
- Kavanagh Marcel Marjanović
- Kazan Ozgur
- Kealey Joshua
- Kebede Ephrem
- Kedwany Ahmed
- Kelly Michael
- Ken-Amoah Sebastian
- Kenington Cleo
- Kennerton A.S.
- Kent Alistair J
- Keramati Mohammad Reza
- Kethy Fagnon
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- Lohmann Tibor Karl
- Lohse Helmut Alfredo Segovia
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- Lyra Humberto Fenner
- Mabood Waleed
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- Maguire Patrick J.
- Mahečić Tina Tomić
- Mahmood Fahad
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- Mallmann Christoph
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- Mambrilla Sara
- Manangi Mallikarjuna
- Manesh Hassan Fatemi
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- Manigrasso Michele
- Manjula S.
- Mannan Syed
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- Martins Ana
- Martins Claudia Pinto
- Martins Paulo N.
- Martínez Daniel Fernández
- Martínez Eunate Ganuza
- Martínez Verónica Martín
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- Matthews Emily
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- Maurus Christine
- Mayer Horacio F.
- Mayo-Yáñez Miguel
- Mazzarella Gennaro
- Mbodi Langanani
- Mbwele Bernard
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- McLeish Bethan
- McPherson Duncan
- Meara John G.
- Meead Adullah
- Mehraj Asif
- Meilak Joseph
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- Meneghini Simona
- Mengesha Mengistu G.
- Menna Maria Paola
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- Mohamed Guleed
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- Mohamedahmed Ali Yasen Y.
- Mohammed Alhassan Datti
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- Moreau Joshua
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- Morgan Eghosa
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- Moro Ana María Gimeno
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- Morris Richard
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- Mousli Alaa
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- Mustafa Hamid
- Muthu Sathish
- Mutlu Özgecan Piril Zanbak
- Mutter Didier
- Mvukiyehe Jean Paul
- Mwenda Aruyaru Stanley
- Myrelid Par
- Myriokefalitaki Eva
- Méndez Patricia Serrano
- Nabil Fatma
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- Nacion Aeris Jane D.
- Nadi Khaldoun
- Naegele Felix
- Naga Hani
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- Nah Shireen Anne
- Nahm Christopher
- Naimzada Mukhammad David
- Nakano Luis
- Nanjiani Deedar
- Nankivell Paul
- Naranjo Eddy P. Lincango
- Narayanan Vairavan
- Nardo Bruno
- Narvaez-Rojas Alexis Rafael
- Nassar Mahmoud A.
- Nasser Sara
- Nastos Constantinos
- Natale Joseph
- Nataraja Ramesh
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- Navarrete-Peón Alberto
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- Nazer Ahmed
- Nazimi Abd Jabar
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- Neary Colm
- Negoi Ionut
- Negussie Abraham
- Nemeth Marcus
- Nenna Antonio
- Nepogodiev Dmitri
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- Nevins Edward J.
- Newman Samuel
- Ngaserin Sabrina
- Nicholson Gary
- Niewiera Marc
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- Nitschke Christine
- Njokanma Iloba
- Noel Colin
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- Novysedlák René
- Ntalouka Maria P.
- Ntirenganya Faustin
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- Pettigrove K.L.
- Phillips Jonathan
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- Pieteris Linas
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- Pilkington Isobel
- Pillerstorff Robert
- Pineda Ana Mejía
- Pinkney Thomas
- Pinney L.
- Pinotti Enrico
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- Piozzi Guglielmo Niccolò
- Pira Biagia La
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- Pirola Giacomo Maria
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- Prada Carlos
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- Prijović Nebojša
- Prodromidou Anastasia
- Proud David
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- Prusty Lydia
- Pu Jingya Jane
- Pucher Philip
- Punjabi Prakash P
- Puri Ajay
- Purich Kieran
- Pérez Beatriz Gómez
- Pérez-Bertólez Sonia
- Qader Kawthar
- Qin Kirby R.
- Quadri Oladeji
- Quaresima Silvia
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- Ragozzino Roberta
- Rahman Atiqur
- Rahy-Martín Aida Cristina
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- Raja Anand
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- Rajendram Rajkumar
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- Raphael Marie-Claire
- Raptis Dimitri Aristotle
- Rasheed Aqsa
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- Ratto Carlo
- Rauf Umme Habiba Abdul
- Raurich-Leandro Jordi
- Rausa Emanuele
- Raut Chandrajit
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- Ravindra Raevin
- Raymond Thomas
- Rayner Anthony
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- Recinos Gustavo
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- Redondo Nuria Villacé
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- Reemst Peter
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- Reim Daniel
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- Rela Mariam
- Render Luke
- Reyes Jeryl Anne Silvia
- Rezende Ricardo Fernandes
- Rhomberg Thomas
- Ribeiro João
- Riccetti Camilla
- Richard H.
- Rickard Jennifer
- Rincón Natalia Andrea Rivera
- Ripollés-Melchor Javier
- Risaliti Matteo
- Risteski Toni
- Rius Malena
- Rizzo Davide
- Roberts David
- Robo Ilma
- Roditis Konstantinos
- Rodrigues Diana
- Rodrigues Gabriel
- Rodrigues Sara Castanheira
- Rodriguez H. Alejandro
- Rodriguez Magdiel
- Rodriguez-Lopez Mario
- Rodríguez Lorena Varela
- Rokohl Alexander Christopher
- Roland Christina L
- Rolinger Jens
- Romano Angela
- Romano Maurizio
- Romanzi Andrea
- Romera Jorge Sanz
- Romero Patricia
- Ronellenfitsch Ulrich
- Ros Emilio Peña
- Rosa Fausto
- Rosati Riccardo
- Roscio Francesco
- Ross Samuel
- Rossaak Jeremy
- Rottoli Matteo
- Rotunno Giuseppe
- Roux Simon Le
- Rowe Christopher
- Rudic Milan
- Ruggiero Silvia
- Ruiz-Marín Miguel
- Russo Antonino
- Russo Giorgio Ivan
- Russo Iris Shari
- Ryalino Christopher
- Ryan James
- Ryan Éanna
- Saad Rema
- Saaid Rahmah
- Sabbagh Abdulrahman J.
- Sabella Danielle
- Sablotzki Armin
- Sacdalan Marie Dione
- Sachdev Gaurav
- Sachdeva Ashwin
- Sacras Maria Luís
- Sadia Uzma
- Saed Abdel
- Saeed Summaya
- Saeed Umar
- Safi Seyer
- Safranovs Toms Janis
- Sagnotta Andrea
- Saguil Esther
- Sahni Arun
- Sahu Mo
- Saibene Alberto Maria
- Saif Areeba
- Sakakushev Boris
- Sakhov Orazbek
- Sakr Ahmed
- Salah Rokeya
- Salamanca Omar
- Salameh Fadi-Tamas
- Salami Omotayo
- Sale Danjuma
- Saleh Ismail Ali
- Saleh Ma'Moun
- Salem Hani
- Salem Moacyr
- Salisu Ibrahim
- Salizzoni Stefano
- Sall Ibrahima
- Sallam Asser
- Salunke Pravin
- Salö Martin
- Samadov Elgun
- Saman Pradeep I.H.D.
- Samara Athina
- Samara Evangelia
- Sambhwani Sharan
- Sammour Tarik
- Samo Khursheed Ahmed
- Sandri Giovanni Battista Levi
- Sanli Ahmet Necati
- Santini Alasdair
- Santoro Antonio
- Santos-Costa Paulo
- Santoshi John Ashutosh
- Santric Veljko
- Sapienza Paolo
- Saponaro Gianmarco
- Saraceno Federica
- Saracoglu Ayten
- Saracoglu Kemal
- Sari Ramazan
- Sarjanoja Elise
- Sars Carl
- Sasia Diego
- Sasireka Veerasamy
- Satchithanantham Vinojan
- Satoskar Savni
- Sayed A. Emad
- Sayyed Raza
- Scabini Stefano
- Scacchi Andrea
- Scafa Anthony Kevin
- Scaramuzzo Rosa
- Scaravilli Luca
- Scaringi Stefano
- Schache Andrew
- Schiavone Vincenzo
- Schizas Dimitrios
- Schizas Nikolaos
- Schmitt Françoise
- Schmitz-Rixen Thomas
- Schneck Emmanuel
- Schröder Lars
- Schweitzer Donald
- Scifo Amedeo
- Scopelliti Michele
- Scott Erin
- Seah Kt Matthew
- Sebai Amine
- Seeliger Barbara
- Seenivasagam Rajkumar Kottayasamy
- Segalini Edoardo
- Segaren Neil
- Segaren Nicholas
- Seglenieks Richard
- Segura-Sampedro Juan José
- Seguya Amina
- Seidu Anwar Sadat
- Seiwerth Ingmar
- Sekulić Aleksandar
- Semple Abigail
- Sen Comert
- Senanayake Kithsiri Janakantha
- Senent-Boza Ana
- Seneviratne Sanjeewa
- Senni Carlotta
- Sensi Bruno
- Seraj Shaikh Sanjid
- Serban Andreea-Madalina
- Serenari Matteo
- Serra Margherita
- Serra Marta Lopes
- Seshadri Ramakrishnan Ayloor
- Sethi Aman
- Seyfried Steffen
- Seyi-Olajide Justina
- Sečan Tomislav
- Sgarzani Rossella
- Shaban Naseebah
- Shaddad Ebrahim
- Shaerf Daniel
- Shah Faaiz Ali
- Shah Hemina
- Shah Jaffer
- Shah Karishma
- Shah Pritik A
- Shah Vinay
- Shaikh Shafaque
- Shalaby Mostafa
- Shalhoub Joseph
- Shamim Shahzad
- Sharma Naveen
- Sharma Neil
- Sharma Rahul Deo
- Sharma Shilpa
- Sharpin Claire
- Sheen Jonathon
- Shehata Sherif
- Shehta Ahmed
- Sheik Shahila
- Sheikh Eman
- Shekleton Florence
- Shelat Vishal
- Shelmerdine Lauren
- Sherif Ahmed Elshawadfy
- Shiban Ehab
- Shiota Masaki
- Shirazi Ahmed
- Shiwani Haaris
- Shmukler Daniel
- Shokor Muntaser Abu
- Sholadoye Tunde T.
- Shoukrie Shoukrie I. M.
- Shrestha Rashmit
- Siboe Mark
- Sica Giuseppe
- Siddig Esra
- Siddiqui M. Tayyab
- Sidiropoulos Theodoros
- Sievers Denise
- Sigamoney Kohila
- Silvestri Vania
- Simoes Joana
- Simon Natalie
- Simoncini Tommaso
- Simões Joana Filipa Ferreira
- Singer Georg
- Singh Abhinav
- Singh Baljit
- Singh Kathryn
- Singh Rajdeep
- Singh Tanveer
- Sinnerton Robert
- Siragusa Leandro
- Sivaprakasam Rajesh
- Skipworth Richard Je
- Slavchev Mihail
- Sleem Adham
- Smati Ismail
- Smelt Jeremy
- Smith A.
- Smolle-Juettner Freyja-Maria
- Sodhai Vivek
- Sofi Khalid
- Sohrabi Catrin
- Soibiharry Adaiah
- Sokolov Manol
- Solaini Leonardo
- Sole Oriol Martin
- Sole-Sedeno Josep M.
- Soljic Martina
- Solli Piergiorgio
- Soon Wai Cheong
- Sorbi Flavia
- Sotiropoulou Maria
- Sotudeh Mohadeseh
- Souadka Amine
- Soucheiron Maria Coronas
- Soytas Mustafa
- Sozzi Giulio
- Sparavigna Marco
- Spartalis Michael
- Spellar Kayleigh
- Spiers Harry V. M.
- Spina Alfio
- Spriano Giuseppe
- Squiers John
- Stabler Robert
- Stamatakis Emmanouil
- Stamatis Konstantinos
- Starr Nichole
- Stather Philip
- Stevens Sean
- Stevenson Andrew
- Stewart Grant D.
- Stijns Jasper
- Stogowski Piotr Tomasz
- Stoleriu Mircea Gabriel
- Stoyanov Vladislav
- Street John
- Strotmann Johanna Josefine
- Stroumpoulis Konstantinos
- Su Yu-Xiong
- Suarez Sara Busto
- Subramani Yamini
- Subramaniam Sentilnathan
- Sue-Chue-Lam Colin
- Suer Muhammed Salih
- Sulaiman Bilal
- Sultania Mahesh
- Sundarraju Shalini
- Sungurtekin Hulya
- Suresh Sreelakshmi
- Surya Ilham Utama
- Swed Sarya
- Syllaios Athanasios
- Symeonidis Dimitrios
- Szabómihályová Katarína
- Szakmany Tamas
- Szatmary Peter
- Sztipits Tamás
- Szyluk Karol
- Sá-Marta Eduarda
- Sánchez Alberto Cabañero
- Sánchez Rosa
- Sánchez-Guillén Luis
- Süleyman Marlen
- Tadic Boris
- Taha Anas
- Taha-Mehlitz Stephanie
- Tailor Bhavesh
- Taj Eldeen Samaher Taj Eldeen Hassan
- Takeda Flavio Roberto
- Takkenberg Marijn
- Talat Nabila
- Tallon-Aguilar Luis
- Talwar Rishi
- Tamayo Beatriz Villota
- Tamburello Sara
- Tamini Nicolò
- Tammo Ömer
- Tamoos Khalil
- Tampaki Ekaterini Christina
- Tampakis Athanasios
- Tan Chih Ying
- Tan Shawn Jia Hwang
- Tanal Mert
- Tanas Yousef
- Tang Alethea
- Tang Yita
- Tani Sobhana Iftekhar
- Tantraworasin Apichat
- Tantri Aida Rosita
- Tapia-Herrero Ana-María
- Tarek Ahmed
- Tariq Aiman
- Tarle Marko
- Tarsitano Achille
- Tartaglia Dario
- Tartaglia Nicola
- Tashkandi Wail
- Taskiran Cagatay
- Tatar Cihad
- Tatsis Dimitris
- Tawalbeh Ra'Fat
- Tawiah Augustine
- Tebha Sameer
- Techapongsatorn Suphakarn
- Teixeira Pedro
- Tejero-Pintor Francisco J.
- Tellez Karla Susana Martin
- Tellez Luis Garcia-Sancho
- Thaha Mohamed Adhnan
- Thakar Sumit
- Thaw May Htoo
- Theivendran Kanthan
- Thekkinkattil Dinesh
- Theochari Nikoletta
- Theodoropoulos George
- Theophilidou Elena
- Thereska Dariel
- Thiruchandran Gajendiran
- Thomakos Nikolaos
- Thomas Bradley
- Thomas Jerin Jose
- Thuduvage Vasanthika
- Thumbadoo Ruben
- Tian Sarah
- Tidjane Anisse
- Tirloni Luca
- Toia Francesca
- Tokidis Evripidis
- Tokocin Merve
- Tolani Musliu Adetola
- Toma Elena Adelina
- Tomasicchio Giovanni
- Tomlinson James
- Tonini Valeria
- Torre Beatrice
- Torregrosa Cristina
- Torun Bahar Canbay
- Tottman R.
- Tousidonis Manuel
- Trabulsi Nora
- Tranca Sebastian
- Trebol Jacobo
- Trejo-Avila Mario
- Triantafyllou Alexandra
- Triantafyllou Tania
- Trifunovski Aleksandar
- Tripathi Manjul
- Tripathi Prashant
- Tripathy Sujit
- Trivik-Barrientos Felipe
- Trostchansky Ivan
- Trulson Alexander
- Trungu Sokol
- Truss Adam
- Tsakiridis Ioannis
- Tsakiridis Nikolaos
- Tsiantoula Paraskevi
- Tsironis Dimitrios
- Tsolakidis Alexandros
- Tsoulfas Georgios
- Tucker Olga
- Tuech Jean Jacques
- Turan Alparslan
- Turi Stefano
- Turna Akif
- Turrado-Rodriguez Victor
- Turri Giulia
- Tutino Roberta
- Tuyishime Eugene
- Tzelves Lazaros
- Tzima Ioanna
- Tzimas George
- Ubiali Paolo
- Ubom Akaninyene Eseme
- Ugwu Aloy Okechukwu
- Ugwu Ebere
- Ugwu Ifeanyichukwu
- Ul Huda Maria Noor
- Ulas Ali Bilal
- Uldry Emilie
- Ulgur Hanife Seyda
- Ulkucu Attila
- Ulman Elif Akbas
- Ulman Hilmican
- Ulutaş Mehmet Eşref
- Underwood Kirk
- Unsworth Richard
- Uprak Tevfik Kivilcim
- Urriza Pablo Vallés
- Usman Muhammad
- Usman Mustapha Ibrahim
- Vaassen Lauretta
- Vaccara Vincenzo La
- Vagena Xanthoula
- Vagge Aldo
- Vailas Michail
- Valadez Andrea Estefania Cueto
- Valadez Tania Abigail Cueto
- Valanci Sofia
- Valdespino Cristina Puentes
- Valeanu Liana
- Valioulis Ioannis
- Valladares Sergio Chávez
- Vallve-Bernal Marc
- Van Acker Jill
- Van Den Eynde Jef
- Van Goor Harry
- Van Vliet Helen
- Van Wyk Naomi Natasha
- Vanni Camilla
- Vas Aurelia
- Vasarhelyi Edward
- Vaschetti Roberto
- Vassiliu Panteleimon
- Vatansever Dogan
- Vatish Jamie
- Vaughan-Shaw Peter G.
- Vaysburg Dennis
- Veglia Antonella
- Velten Markus
- Velázquez Maria Jose Martinez
- Venkatappa Sunil Kumar
- Venketeswaran Meenakshi
- Venskutonis Donatas
- Verbic Milena Senica
- Verdi Daunia
- Vergara-Fernandez Omar
- Verhoeff Kevin
- Veroux Massimiliano
- Verras Georgios-Ioannis
- Verre Luigi
- Vida Lucian
- Vidya Raghavan
- Viglietta Edoardo
- Vijay Vardhini
- Vijgen Guy
- Vilaró Blanca Capdevila
- Villanueva Julio
- Vilz Tim O.
- Vincent Elizabeth
- Vinci Danilo
- Viola Simona
- Violante Tommaso
- Vishnoi Jeewan Ram
- Vissapragada Ravi
- Vivancos Laura Guillamon
- Vives Josep Maria Muñoz
- Vizzielli Giuseppe
- Vohra Lubna
- Vokshi Ismail
- Vosinakis Christos
- Vásquez Javier Alberto Gutiérrez
- Vázquez Gil
- Vázquez Irene Ortega
- Vǎcǎraşu Andrei Bogdan
- Wade Ryckie
- Wafi Omar
- Wagner Gabriela
- Wallis Christopher
- Wanjara Samuel
- Waqar Shahzad Hussain
- Warden Claire
- Warner Christian
- Wasim D.
- Wason Shaun
- Wasserman Isaac
- Watcyn-Jones Tom
- Waterson Ben
- Watson David
- Watson Matthew
- Weber Clemens
- Wheatstone P.
- Wheeler James
- Wheldon Luke
- White Michelle
- White Stuart
- White William
- Wickramasinghe Dakshitha
- Widmer Lukas Werner
- Wiedemann Dominik
- Wiesinger Clemens Georg
- Wijekoon Naveen
- Wijenayake Wasantha
- Wijeyaratne Manuk
- Wijeysundera Duminda
- Wiles Matthew
- Wilkin Richard
- Wilkins Alex
- Wilkins James
- William Tinka George
- Williams Omolara Modupe
- Williams Shekinah
- Windsor John
- Winnand Philipp
- Wittmann Maria
- Wolde Amanuel
- Wolfenden John W. D.
- Wong Benjamin Ngie Xiong
- Wong Enoch
- Wong Evan G.
- Wong George Kwok Chu
- Wong Ho Ying Flora
- Wong Kai Yuen
- Wormald Justin
- Wright Deborah
- Wright Joshua
- Wu Fiona
- Wurm Markus
- Xenaki Sofia
- Yadev Ip
- Yahaya Ahmad Shuib
- Yakubu Mustapha
- Yang Wah
- Yanik Özge
- Yanowsky-Reyes Guillermo
- Yassin Abubaker
- Yates Elizabeth
- Yebes Alvaro
- Yenli Edwin Mwintiereh Ta-Ang
- Yeoh Tien
- Yeung Justin
- Yiallourou Anneza
- Yigit Banu
- Yildirim Asif
- Yim Guang
- Yiu Andrew
- Yonekura Hiroshi
- Yotsov Tsanko
- Younis Muhammad Umar
- Yunus Alif
- Yusefi Hossein
- Zabaleta Jon
- Zabkiewicz Catheriner
- Zaccaria Giulia
- Zacharia Bincy
- Zafar Syed Nabeel
- Zago Mauro
- Zaheen Zakia
- Zahid Zahra
- Zaimis Tilemachos
- Zakaria Andee Dzulkarnaen
- Zambon Martina
- Zamora Lindsey
- Zampogna Biagio
- Zancana Giuseppa
- Zani Augusto
- Zanin Luca
- Zanini Nicola
- Zapardiel Ignacio
- Zapata Carlos Shiraishi
- Zarif Pierre
- Zaránd Attila
- Zehnder Philipp
- Zenger Serkan
- Zenha Horácio
- Zhu Michael Z. L.
- Ziemann Sebastian
- Zimak Danijela Mrazovac
- Zimak Zoran
- Zivkovic Dragana
- Zizzo Maurizio
- Zucker Benjamin
- Zwain Yasir
- Zyskowski Michael
- Ávila Clara Castro
- Älgå Andreas
- Çakici Mehmet Çaǧlar
- Çelik Enes
- Çelik Meryem Nur
- Özçay Necdet
- Şevik Hüsnü
- Šantak Goran
- Šimko Kristián
- Žatecký Jan
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2023
- Field of study
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
Phylogeny and pathogenicity of soilborne fungi associated with wilt disease complex of tomatillo (Physalis ixocarpa) in northern Sinaloa, Mexico
- Author
- A Alves
- A Meza-Moller
- A Meza-Moller
- AK Gupta
- AR Machado
- B Sneh
- BE González-Pacheco
- C Gámez-Jiménez
- E Martínez-Fernández
- FE Enciso-Rodríguez
- G Soto
- G Vaidya
- G Virgen-Calleros
- I Carbone
- IG Güney
- J Méndez-Lozano
- JA Mauricio-Castillo
- JA Osorio-Guarín
- JC Correll
- JD Thompson
- JF Leslie
- KY Leyva-Madrigal
- L Zhao
- LE Datnoff
- M Sandoval-Denis
- MA Tirado-Ramírez
- ME Rentería-Martínez
- ME Santos-Cervantes
- MF Fuhlbohm
- N Mayek-Pérez
- ND Young
- NL Glass
- R De la Torre-Almaráz
- R Elias-Medina
- R Félix-Gastélum
- R Navarrete-Maya
- R Staden
- R Urrea
- RG Shivas
- RM Muñoz-Cabañas
- S Ahmad
- S Kumar
- SIAP
- ST Koike
- TA Vega-Gutiérrez
- TA Vega-Gutiérrez
- V Montero-Tavera
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Variant discovery in the sheep milk transcriptome using RNA sequencing
- Author
- A Ameur
- A Cánovas
- A Djari
- A Dobin
- A McKenna
- A Mortazavi
- A Schennink
- A Suárez-Vega
- A Suárez-Vega
- A Suárez-Vega
- A Suárez-Vega
- A Wetterbom
- AK LeFebvre
- Aroa Suárez-Vega
- B Moioli
- Beatriz Gutiérrez-Gil
- BN Finck
- C Gonzalo
- C Peris
- CA Morris
- Christophe Klopp
- D Karolchik
- E Garcia-Gamez
- E Hodges
- F Zhang
- G Calero
- G Ceriotti
- G Erhardt
- G Picariello
- Gwenola Tosser-Klopp
- H Li
- H Matsumoto
- HD Daetwyler
- IJ Giambra
- J Wang
- JL McManaman
- JL Tetens
- JM Corral
- Juan José Arranz
- K Bell
- K Reue
- L Amigo
- L Andersson
- L Wang
- LA Cox
- M Bionaz
- M Bionaz
- M García-Fernández
- M Georges
- M Laplante
- M Orford
- M Selvaggi
- M Selvaggi
- MA DePristo
- NJ Hudson
- P Cingolani
- P Cingolani
- P Danecek
- P Kumar
- R Piskol
- R Roy
- R Rupp
- RG Mateescu
- RK Gopinath
- S Ali
- S Smith
- S Zhang
- SG Fonseca
- T Abe
- TA Huffman
- TD Russell
- TD Russell
- VJ Peschansky
- VSR Dukkipati
- W McLaren
- XM Song
- Z Wang
- Z-L Hu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Profiling the venom gland transcriptomes of Costa Rican snakes by 454 pyrosequencing
- Author
- A Alape-Girón
- A Conesa
- A Kasturiratne
- A Ménez
- A Ménez
- AL Harvey
- Alberto Alape-Girón
- Ana Conesa
- AT Ching
- B Lomonte
- B McClintock
- B Zhang
- BG Fry
- BG Fry
- BG Fry
- BG Fry
- BG Fry
- BG Fry
- BI Crother
- Bruno Lomonte
- CW Wheat
- D Georgieva
- D Kordis
- D Kordis
- DAP Cidade
- DCI Koh
- DR Rokyta
- DR Zerbino
- E Fasoli
- ER Mardis
- FJ Vonk
- G Naamati
- GL Law
- GP Espino-Solis
- HL Gibbs
- HW Deng
- HW Greene
- I Vetter
- ILM Junqueira de Azevedo
- ILM Junqueira-de-Azevedo
- ILM Junqueira-de-Azevedo
- J Fernández
- J Fleischmann
- JA Campbell
- JF Hughes
- JJ Calvete
- JJ Calvete
- JJ Calvete
- JJ Calvete
- JJ Calvete
- JM Gutiérrez
- JM Gutiérrez
- Joaquín Dopazo
- Jordi Durban
- José M Gutiérrez
- JP Chippaux
- JP Chippaux
- JR Walker
- JS Papadopoulos
- Juan J Calvete
- JW Fox
- JW Fox
- KF Huang
- L Kuai
- L Menin
- L Sanz
- LD Dos Santos
- Libia Sanz
- LN van de Lagemaat
- LS Wermelinger
- M Margulies
- M Nei
- M Neiva
- M Ohno
- Mahmood Sasa
- Marietta Flores-Diaz
- MD Adams
- MJ Paine
- MK Kuhner
- N Bannert
- N Ikeda
- ND Rawlings
- O Morozova
- P Escoubas
- P Escoubas
- P Flicek
- P Jern
- P Juárez
- P Medstrand
- Paula Juárez
- PL Deininger
- PL Ho
- Q He
- Q Liu
- Q Lu
- R Doley
- RB Freedman
- RC Edgar
- RC Rodríguez de la Vega
- RH Valente
- S Decuypere
- S Kashima
- S Kumar
- S Linnarsson
- S Pahari
- S Slomovic
- SC Wagstaff
- SC Wagstaff
- SC Wagstaff
- SF Altschul
- SM Munekiyo
- SP Mackessy
- T Preiss
- TA Castoe
- TA Castoe
- TA Castoe
- TA Castoe
- TA Castoe
- The Gene Ontology Consortium
- VJ Lynch
- VL MacKay
- W Pi
- W Wang
- World Health Organization
- Y Angulo
- Y Arava
- Y Yao
- Yamileth Angulo
- Z Wang
- Z Yang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2011
- Field of study
Background: A long term research goal of venomics, of applied importance for improving current antivenom
therapy, but also for drug discovery, is to understand the pharmacological potential of venoms. Individually or
combined, proteomic and transcriptomic studies have demonstrated their feasibility to explore in depth the
molecular diversity of venoms. In the absence of genome sequence, transcriptomes represent also valuable
searchable databases for proteomic projects.
Results: The venom gland transcriptomes of 8 Costa Rican taxa from 5 genera (Crotalus, Bothrops, Atropoides,
Cerrophidion, and Bothriechis) of pitvipers were investigated using high-throughput 454 pyrosequencing. 100,394
out of 330,010 masked reads produced significant hits in the available databases. 5.165,220 nucleotides (8.27%)
were masked by RepeatMasker, the vast majority of which corresponding to class I (retroelements) and class II
(DNA transposons) mobile elements. BLAST hits included 79,991 matches to entries of the taxonomic suborder
Serpentes, of which 62,433 displayed similarity to documented venom proteins. Strong discrepancies between the
transcriptome-computed and the proteome-gathered toxin compositions were obvious at first sight. Although the
reasons underlaying this discrepancy are elusive, since no clear trend within or between species is apparent, the
data indicate that individual mRNA species may be translationally controlled in a species-dependent manner. The
minimum number of genes from each toxin family transcribed into the venom gland transcriptome of each
species was calculated from multiple alignments of reads matched to a full-length reference sequence of each
toxin family. Reads encoding ORF regions of Kazal-type inhibitor-like proteins were uniquely found in Bothriechis
schlegelii and B. lateralis transcriptomes, suggesting a genus-specific recruitment event during the early-Middle
Miocene. A transcriptome-based cladogram supports the large divergence between A. mexicanus and A. picadoi,
and a closer kinship between A. mexicanus and C. godmani.
Conclusions: Our comparative next-generation sequencing (NGS) analysis reveals taxon-specific trends governing
the formulation of the venom arsenal. Knowledge of the venom proteome provides hints on the translation
efficiency of toxin-coding transcripts, contributing thereby to a more accurate interpretation of the transcriptome.
The application of NGS to the analysis of snake venom transcriptomes, may represent the tool for opening the
door to systems venomics.Universidad de Costa Rica, Instituto Clodomiro PicadoUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP
Theoretical models to predict the inhibitory effect of ligands of sphingosine kinase 1 using QTAIM calculations and hydrogen bond dynamic propensity analysis
- Author
- A Siano
- AM Luchi
- BW Wattenberg
- C Ricci
- CA Menendez
- CA Menendez
- Cintia Menéndez
- DA Case
- DJ Gustin
- E Durham
- EE Barrera Guisasola
- EG Vega-Hissi
- EL Angelina
- GM Morris
- Gustavo Appignanesi
- J Parraga
- J Parraga
- J Wang
- J Wang
- JA Izaguirre
- JE Ortiz
- K Lindorff-Larsen
- KA Orr Gandy
- KJ French
- LJ Gutierrez
- LJ Gutierrez
- LJ Gutierrez
- LJ Gutierrez
- Lucas Gutiérrez
- M Maceyka
- M Vettorazzi
- Marcela Vettorazzi
- ME Schnute
- NC Hait
- O Cuvillier
- P Mark
- PA Kollman
- R Tosso
- RD Tosso
- RFW Bader
- Ricardo D. Enriz
- S Andujar
- S Lima
- Sebastián Andujar
- SW Paugh
- T Lu
- TA Taha
- U Essmann
- Z Wang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Social Performance considered within the global performance of Microfinance Institutions: a new approach
- Author
- A Ashta
- A Charnes
- A Charnes
- A Hollis
- A Islam
- A Silva Da
- AP Wierzbicki
- B Barnett
- B Gutiérrez-Nieto
- B Rogaly
- C Ahlin
- C González-Vega
- C Romero
- C Romero
- CGAP
- D Diakoulaki
- Dalberg
- E Ballestero
- E Barinaga
- F García
- F García
- Francisco Guijarro
- G García-Martínez
- H Deng
- J Copestake
- J González-Pachón
- J Morduch
- J Prišenk
- J Skees
- J Yaron
- JM Ignizio
- K Brandon
- K Jonker
- LS Ortobelli
- M Hoque
- M Wijesiri
- MB Jones
- Microfinance Information Exchange
- N Hermes
- O Weber
- P Linares
- R Mersland
- Roberto Cervelló-Royo
- TA Barry
- TL Saaty
- V Hartarska
- Victor Martinez-Gomez
- W Akpalu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Nitric Oxide Not Apoptosis Mediates Differential Killing of Mycobacterium bovis in Bovine Macrophages
- Author
- AK Randhawa
- Alejandro Benítez-Guzmán
- Antonio J. Vallecillo
- C Thoen
- CJ Martin
- DG Pritchard
- DL Clemens
- DP Gil
- E Liebana
- GA Campbell
- H Pan
- Hugo Esquivel-Solís
- IP Fairbairn
- J Feng
- J Keane
- J Keane
- J McNair
- J Piercy
- JA Gutierrez-Pabello
- JE Albina
- JM Pollock
- José A. Gutiérrez-Pabello
- JP Cassidy
- JS Ferguson
- JS Park
- L Bosca
- L. Garry Adams
- M Arias
- M Denis
- M Denis
- M Denis
- M Rojas
- MD Sanchez
- MF Rodrigues
- ML Arcila
- N Kumar
- P Horin
- P Laochumroonvorapong
- R Barthel
- R Barthel
- R Placido
- S Widdison
- Stephen V. Gordon
- T Garnier
- T Qureshi
- TA Paixao
- U Castillo-Velazquez
- UE Schaible
- WR Berrington
- WR Waters
- X Vega-Manriquez
- Yolanda López-Vidal
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study