To Avoid or Not to Avoid? Factors Influencing the Discrimination or Predator Diet Cues by a Terrestrial Salamander

Many prey species use chemical cues deposited by predators to assess predation risk, and some prey are capable of discriminating among predator chemical traces based on the predator’s recent diet. Here we test the influence of genetic relatedness (degree of genetic similarity between prey) and ecological relatedness (degree of refuge and trophic overlap between syntopic prey) on the evolution of predator-diet discrimination by red-backed salamanders, Plethodon cinereus. In experiment 1, we examined whether red-backed salamanders from Binghamton University (Binghamton, New York, U.S.A.) would differentially respond to chemical traces from garter snakes (Thamnophis sirtalis) fed conspecific P. cinereus from four populations belonging to three phylogenetic groups: Group II from Mountain Lake, Virginia, Group III from Binghamton University, New York, Group III from Hawk Mountain, Pennsylvania, and Group IV from Cherry Springs, Pennsylvania, U.S.A. The test salamanders only avoided chemical traces from garter snakes fed salamanders from the two Group III sites, although the response to the Group III-Hawk Mountain treatment was intermediate to that for the Group III-Binghamton University treatment and the Group II and IV treatments. In experiment 2, we examined whether red-backed salamanders collected from two subpopulations, syntopic or allotopic with two-lined salamanders, Eurycea bislineata, vary in their response to chemical cues from garter snakes foraging on two-lined salamanders. Only red-backed salamanders syntopic with E. bislineata avoided chemical traces from garter snakes fed E. bislineata. These results suggest that both genetic and ecological relatedness play a role in the evolution of predator-diet discrimination in red-backed salamanders

Considerations with using unmanned aircraft systems in turfgrass

In recent years, small unmanned aircraft systems (sUAS) and advancements in remote sensing technology have provided alternative and more affordable means for monitoring crop health and stress than ground-based (hand-held or vehicle-mounted) or other aerial-based platforms (manned aircraft or satellites). However, few scientific studies have evaluated the application of sUAS in turfgrass systems. The use of sUAS in monitoring turfgrass requires an understanding of basic remote sensing principles; identifying the target of interest and the various sUAS platforms and sensors that provide the necessary resolution and frequencies to measure and monitor that target; calibration of sensors in the field; and data processing considerations. Those topics are discussed, followed by reviews of recent turfgrass field studies conducted to predict and manage drought stress and pest outbreaks, and improve phenotyping capabilities in turfgrass breeding programs. The use of sUAS remote sensing in turfgrass offers unique possibilities and challenges, which are addressed herein

Academic self-concept, gender and single-sex schooling

This paper assesses gender differences in academic self-concept for a cohort of children born in 1958 (the National Child Development Study). We address the question of whether attending single-sex or co-educational schools affected students’ perceptions of their own academic abilities (academic self-concept). Academic selfconcept was found to be highly gendered, even controlling for prior test scores. Boys had higher self-concepts in maths and science, and girls in English. Single-sex schooling reduced the gender gap in self-concept, while selective schooling was linked to lower academic self-concept overall

Phenotype and envelope gene diversity of nef-deleted HIV-1 isolated from long-term survivors infected from a single source

<p>Abstract</p> <p>Background</p> <p>The Sydney blood bank cohort (SBBC) of long-term survivors consists of multiple individuals infected with attenuated, <it>nef</it>-deleted variants of human immunodeficiency virus type 1 (HIV-1) acquired from a single source. Long-term prospective studies have demonstrated that the SBBC now comprises slow progressors (SP) as well as long-term nonprogressors (LTNP). Convergent evolution of <it>nef </it>sequences in SBBC SP and LTNP indicates the <it>in vivo </it>pathogenicity of HIV-1 in SBBC members is dictated by factors other than <it>nef</it>. To better understand mechanisms underlying the pathogenicity of <it>nef</it>-deleted HIV-1, we examined the phenotype and <it>env </it>sequence diversity of sequentially isolated viruses (n = 2) from 3 SBBC members.</p> <p>Results</p> <p>The viruses characterized here were isolated from two SP spanning a three or six year period during progressive HIV-1 infection (subjects D36 and C98, respectively) and from a LTNP spanning a two year period during asymptomatic, nonprogressive infection (subject C18). Both isolates from D36 were R5X4 phenotype and, compared to control HIV-1 strains, replicated to low levels in peripheral blood mononuclear cells (PBMC). In contrast, both isolates from C98 and C18 were CCR5-restricted. Both viruses isolated from C98 replicated to barely detectable levels in PBMC, whereas both viruses isolated from C18 replicated to low levels, similar to those isolated from D36. Analysis of <it>env </it>by V1V2 and V3 heteroduplex tracking assay, V1V2 length polymorphisms, sequencing and phylogenetic analysis showed distinct intra- and inter-patient <it>env </it>evolution.</p> <p>Conclusion</p> <p>Independent evolution of <it>env </it>despite convergent evolution of <it>nef </it>may contribute to the <it>in vivo </it>pathogenicity of <it>nef</it>-deleted HIV-1 in SBBC members, which may not necessarily be associated with changes in replication capacity or viral coreceptor specificity.</p

Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo

In efforts to develop an effective vaccine, sterilizing immunity to primate lentiviruses has only been achieved by the use of live attenuated viruses carrying major deletions in nef and other accessory genes. Although live attenuated HIV vaccines are unlikely to be developed due to a myriad of safety concerns, opportunities exist to better understand the correlates of immune protection against HIV infection by studying rare cohorts of long-term survivors infected with attenuated, nef-deleted HIV strains such as the Sydney blood bank cohort (SBBC). Here, we review studies of viral evolution, pathogenicity, and immune responses to HIV infection in SBBC members. The studies show that potent, broadly neutralizing anti-HIV antibodies and robust CD8+ T-cell responses to HIV infection were not necessary for long-term control of HIV infection in a subset of SBBC members, and were not sufficient to prevent HIV sequence evolution, augmentation of pathogenicity and eventual progression of HIV infection in another subset. However, a persistent T-helper proliferative response to HIV p24 antigen was associated with long-term control of infection. Together, these results underscore the importance of the host in the eventual outcome of infection. Thus, whilst generating an effective antibody and CD8+ T-cell response are an essential component of vaccines aimed at preventing primary HIV infection, T-helper responses may be important in the generation of an effective therapeutic vaccine aimed at blunting chronic HIV infection

PTF10fqs: A Luminous Red Nova in the Spiral Galaxy Messier 99

The Palomar Transient Factory (PTF) is systematically charting the optical transient and variable sky. A primary science driver of PTF is building a complete inventory of transients in the local Universe (distance less than 200 Mpc). Here, we report the discovery of PTF10fqs, a transient in the luminosity "gap" between novae and supernovae. Located on a spiral arm of Messier 99, PTF 10fqs has a peak luminosity of Mr = -12.3, red color (g-r = 1.0) and is slowly evolving (decayed by 1 mag in 68 days). It has a spectrum dominated by intermediate-width H (930 km/s) and narrow calcium emission lines. The explosion signature (the light curve and spectra) is overall similar to thatof M85OT2006-1, SN2008S, and NGC300OT. The origin of these events is shrouded in mystery and controversy (and in some cases, in dust). PTF10fqs shows some evidence of a broad feature (around 8600A) that may suggest very large velocities (10,000 km/s) in this explosion. Ongoing surveys can be expected to find a few such events per year. Sensitive spectroscopy, infrared monitoring and statistics (e.g. disk versus bulge) will eventually make it possible for astronomers to unravel the nature of these mysterious explosions.Comment: 12 pages, 12 figures, Replaced with published versio

The infrared supernova rate in starburst galaxies

We report the results of our ongoing search for extincted supernovae (SNe) at near-infrared wavelengths. We have monitored at 2.2 micron a sample of 46 Luminous Infrared Galaxies and detected 4 SNe. The number of detections is still small but sufficient to provide the first estimate of supernova rate at near-infrared wavelengths. We measure a SN rate ofv 7.6+/-3.8 SNu which is an order of magnitude larger than observed in quiescent galaxies. On the other hand, the observed near-infrared rate is still a factor 3-10 smaller than that estimated from the far-infrared luminosity of the galaxies. Among various possibilities, the most likely scenario is that dust extinction is so high (Av>30) to obscure most SNe even in the near-IR. The role of type Ia SNe is also discussed within this context. We derive the type Ia SN rate as a function of the stellar mass of the galaxy and find a sharp increase toward galaxies with higher activity of star formation. This suggests that a significant fraction of type Ia SNe are associated with young stellar populations. Finally, as a by-product, we give the average K-band light curve of core-collapse SNe based on all the existing data, and review the relation between SN rate and far-infrared luminosity.Comment: A&A, in press, 13 page

Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders

Personality is influenced by genetic and environmental factors1 and associated with mental health. However, the underlying genetic determinants are largely unknown. We identified six genetic loci, including five novel loci2,3, significantly associated with personality traits in a meta-analysis of genome-wide association studies (N = 123,132–260,861). Of these genomewide significant loci, extraversion was associated with variants in WSCD2 and near PCDH15, and neuroticism with variants on chromosome 8p23.1 and in L3MBTL2. We performed a principal component analysis to extract major dimensions underlying genetic variations among five personality traits and six psychiatric disorders (N = 5,422–18,759). The first genetic dimension separated personality traits and psychiatric disorders, except that neuroticism and openness to experience were clustered with the disorders. High genetic correlations were found between extraversion and attention-deficit– hyperactivity disorder (ADHD) and between openness and schizophrenia and bipolar disorder. The second genetic dimension was closely aligned with extraversion–introversion and grouped neuroticism with internalizing psychopathology (e.g., depression or anxiety)

Determining Star Formation Rates for Infrared Galaxies

We show that measures of star formation rates (SFRs) for infrared galaxies using either single-band 24 um or extinction-corrected Paschen-alpha luminosities are consistent in the total infrared luminosity = L(TIR) ~ 10^10 L_sun range. MIPS 24 micron photometry can yield star formation rates accurately from this luminosity upward: SFR(M_sun/yr) = 7.8 x 10^-10 L(24 um, L_sun) from L(TIR) = 5 x 10^9 L_sun to 10^11 L_sun, and SFR = 7.8 x 10^-10 L(24 um, L_sun) x (7.76 x 10^-11 L(24))^0.048 for higher L(TIR). For galaxies with L(TIR) >= 10^10 L_sun, these new expressions should provide SFRs to within 0.2 dex. For L(TIR) >= 10^11 L_sun, we find that the SFR of infrared galaxies is significantly underestimated using extinction-corrected Pa-alpha (and presumably using any other optical or near infrared recombination lines). As a part of this work, we constructed spectral energy distribution (SED) templates for eleven luminous and ultraluminous purely star forming infrared galaxies (LIRGs and ULIRGs) and over the spectral range 0.4 microns to 30 cm. We use these templates and the SINGS data to construct average templates from 5 microns to 30 cm for infrared galaxies with L(TIR) = 5 x 10^9 to 10^13 L_sun. All of these templates are made available on line.Comment: Accepted by ApJ. Revised in proof to strengthen caveats about the extrapolation of these IR templates above L(TIR)>2e12, without suitable local purely starforming template galaxies above this luminosity. Source includes two machine-readable tables of template spectra SEDs, or download the tables from http://mingus.as.arizona.edu/~bjw/ir_templates

A Deep Halpha Survey of Galaxies in the Two Nearby Clusters Abell1367 and Coma: The Halpha Luminosity Functions

We present a deep wide field Halpha imaging survey of the central regions of the two nearby clusters of galaxies Coma and Abell1367, taken with the WFC at the INT2.5m telescope. We determine for the first time the Schechter parameters of the Halpha luminosity function (LF) of cluster galaxies. The Halpha LFs of Abell1367 and Coma are compared with each other and with that of Virgo, estimated using the B band LF by Sandage et al. (1985) and a L(Halpha) vs M_B relation. Typical parameters of phi^* ~ 10^0.00+-0.07 Mpc^-3, L^* ~ 10^41.25+- 0.05 erg sec^-1 and alpha ~ -0.70+-0.10 are found for the three clusters. The best fitting parameters of the cluster LFs differ from those found for field galaxies, showing flatter slopes and lower scaling luminosities L^*. Since, however, our Halpha survey is significantly deeper than those of field galaxies, this result must be confirmed on similarly deep measurements of field galaxies. By computing the total SFR per unit volume of cluster galaxies, and taking into account the cluster density in the local Universe, we estimate that the contribution of clusters like Coma and Abell1367 is approximately 0.25% of the SFR per unit volume of the local Universe.Comment: 19 pages, 11 figures, accepted for publication in A&