356 research outputs found

    Gapless fluctuations and exceptional points in semiconductor lasers

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    We analyze the spectrum of spatially uniform, single-particle fluctuation modes in the linear electromagnetic response of a semiconductor laser. We show that if the decay rate of the interband polarization, γp\gamma_p, and the relaxation rate of the occupation distribution, γf\gamma_f, are different, a gapless regime exists in which the order parameter Δ(0)(k)\Delta^{(0)} (k) (linear in the coherent photon field amplitude and the interband polarization) is finite but there is no gap in the real part of the single-particle fluctuation spectrum. The laser being a pumped-dissipative system, this regime may be considered a non-equilibrium analog of gapless superconductivity. We analyze the fluctuation spectrum in both the photon laser limit, where the interactions among the charged particles are ignored, and the more general model with interacting particles. In the photon laser model, the order parameter is reduced to a momentum-independent quantity, which we denote by Δ\Delta. We find that, immediately above the lasing threshold, the real part of the fluctuation spectrum remains gapless when 0<∣Δ∣<2/27 ∣γf−γp∣0 < | \Delta | < \sqrt{2 / 27} \, | \gamma_f - \gamma_p | and becomes gapped when ∣Δ∣| \Delta | exceeds the upper bound of this range. Viewed as a complex function of ∣Δ∣|\Delta| and the electron-hole energy, the eigenvalue set displays some interesting exceptional point (EP) structure around the gapless-gapped transition. The transition point is a third-order EP, where three eigenvalues (and eigenvectors) coincide. Switching on the particle interactions in the full model modifies the spectrum of the photon laser model and, in particular, leads to a more elaborate EP structure. However, the overall spectral behavior of the continuous (non-collective) modes of the full model can be understood on the basis of the relevant results of the photon laser model

    Middle and posterior cardiac veins: An underused option for ventricular pacing

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    Tarrasó, Olga;Fuente Fuente, Carlos;Reventós, Manue

    Retrograde cardioplegia preserves myocardial function after induced coronary air embolism

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    AbstractCoronary air embolism is a potential complication of cardiopulmonary bypass. We compared left ventricular function before and after the administration of antegrade or retrograde cardioplegic solution in a porcine model of coronary air embolism. Nineteen pigs were placed on cardiopulmonary bypass support and cooled to 32° C. The heart was initially arrested with antegrade cold blood cardioplegic solution. The aortic crossclamp was released at 30 minutes and 0.02 cc/kg body weight of air was injected into the left anterior descending artery distal to the first diagonal branch. After 5 minutes the aorta was reclamped and the animals treated with 15 ml/kg body weight of 1:4 blood cardioplegic solution delivered by the antegrade (n = 6) or retrograde (n = 7) method. Control animals (n = 6) were not treated. Changes in regional preload recruitable stroke work were used to assess left ventricular performance before and after cardiopulmonary bypass. Two control animals could not be weaned from cardiopulmonary bypass. Left ventricular function was best preserved after treatment of induced coronary air embolism with retrograde cardioplegia (90% of baseline). Coronary air embolism treatment with antegrade cardioplegia resulted in diminished left ventricular performance (68% of baseline). In control animals left ventricular contractility was significantly impaired (39% of baseline). We conclude that administration of retrograde cardioplegic solution may be an effective method of treating coronary air embolism. The favorable outcome seen with cardioplegia may be in part because of its ability to protect the ischemic myocardium while the solution mechanically dislodges air from the vascular bed. (J Thorac Cardiovasc Surg 1997;113:917-22

    Ischemic Colitis of the Left Colon in a Diabetic Patient

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    Diabetes mellitus may affect the gastrointestinal tract possibly as a result of autonomic neuropathy. Here we present a 68-year-old male with non-insulin-dependent diabetes mellitus who presented with prolonged watery diarrhea and in whom imaging studies demonstrated ischemic colitis of the left colon. Resection of the affected colon resulted in sustained disappearance of symptoms

    Intestinal ischemia after cardiac surgery: analysis of a large registry.

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    Intestinal ischemia after cardiac surgery is a rare but severe complication with a high mortality. Early surgery can be lifesaving. The aim was to analyze the incidence, outcome, and risk factors for these patients

    Electrodeposited lead dioxide coatings

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    Lead dioxide coatings on inert substrates such as titanium and carbon now offer new opportunities for a material known for 150 years. It is now recognised that electrodeposition allows the preparation of stable coatings with different phase structures and a wide range of surface morphologies. In addition, substantial modification to the physical properties and catalytic activities of the coatings are possible through doping and the fabrication of nanostructured deposits or composites. In addition to applications as a cheap anode material in electrochemical technology, lead dioxide coatings provide unique possibilities for probing the dependence of catalytic activity on layer composition and structure (critical review, 256 references)

    A new shape for an old function: lasting effect of a physiologic surgical restoration of the left ventricle

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    BACKGROUND: Long-term morphofunctional outcome may vary widely in surgical anterior left ventricular wall restoration, suggesting variability in post-surgical remodeling similar to that observed following acute myocardial infarction. The aim of this pilot study was to demonstrate that surgical restoration obtained with a particular shape of endoventricular patch leads to steady morphofunctional ventricular improvement when geometry, volume and residual akinesia can be restored as normal as possible. METHODS: This study involved 12 consecutive patients with previous anterior myocardial infarction, dilated cardiomyopathy and no mitral procedures, who underwent left ventricular reconstruction and coronary revascularization between May 2002 and May 2003 using a small, narrow, oval patch aiming at a volume ≤ 45 mL/m(2 )with elliptical shape. Eleven geometric parameters were examined preoperatively and at least 3, 12 and 24 months after the operation by serial echocardiographic studies and evaluated by paired t test taking the time of surgery as a starting point for remodeling. RESULTS: All patients were in NYHA class 1 at follow-up. Patch geometry obtained a conical shape of the ventricle with new apex, physiologic rearrangement of functioning myocardial wall and small residual akinesia. Ventricular changes at the four time-points showed that all parameters improved significantly compared to preoperative values (end-diastolic volume = 184.2 ± 23.9 vs 139.9 ± 22.0, p = 0.001; vs 151.0 ± 33.8, p = 0.06; vs 144.9 ± 34.0, p = 0.38; end-systolic volume = 125.7 ± 20.6 vs 75.2 ± 14.1, p = 0.001; vs 82.1 ± 23.9, p = 0,18; vs 77.1 ± 19.4, p = 0.41) without further changes during follow-up except for wall motion score index (2.0 ± 0.2 to 1.7 ± 0.2, to 1.4 ± 0.2, to 1.3 ± 0.2) and percentage of akinesia (30.4 ± 7.5 to 29.3 ± 4.2, to 19.8 ± 11.6, to 14.5 ± 7.2) which slowly and significantly improved suggesting a positive post-surgery remodeling. CONCLUSION: Ventricular reconstruction caring of physiological shape, volume, revascularization and residual akinesia obtained a steady geometry. Positive remodeling and equalization of geometrical outcome may persistently prevent long-term redilation

    Shear-Thinning Nanocomposite Hydrogels for the Treatment of Hemorrhage

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    Internal hemorrhaging is a leading cause of death after traumatic injury on the battlefield. Although several surgical approaches such as the use of fibrin glue and tissue adhesive have been commercialized to achieve hemostasis, these approaches are difficult to employ on the battlefield and cannot be used for incompressible wounds. Here, we present shear-thinning nanocomposite hydrogels composed of synthetic silicate nanoplatelets and gelatin as injectable hemostatic agents. These materials are demonstrated to decrease in vitro blood clotting times by 77%, and to form stable clot-gel systems. In vivo tests indicated that the nanocomposites are biocompatible and capable of promoting hemostasis in an otherwise lethal liver laceration. The combination of injectability, rapid mechanical recovery, physiological stability, and the ability to promote coagulation result in a hemostat for treating incompressible wounds in out-of-hospital, emergency conditions.United States. Army Research Office (Contract W911NF-13-D-0001)National Institutes of Health (U.S.) (Interdepartmental Biotechnology Training Program NIH/NIGMS 5T32GM008334
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