2,028 research outputs found

    Dealing with “Dilemmas of Difference” in the Workplace

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    Over the course of six months, the University of Pennsylvania Carey Law School’s class “Women, Law, and Leadership” interviewed 55 women between the ages of 25 and 85, all leaders in their respective fields. Nearly half of the women interviewed were women of color, and 10 of the women lived and worked in countries other than the U.S., spanning across Europe, Africa, and Southeast Asia. Threading together the common themes touched upon in these conversations, we gleaned a number of novel insights, distinguishing the leadership trajectories pursued by women who have risen to the heights of their professions. Through thousands of hours of conversation with some of the world’s most influential and powerful women, this study identifies the primary barriers and biases faced by women of diverse backgrounds in the workplace, as well as the strategies and philosophies they adopted in order to overcome these impediments. While there is much commonality among the women’s experiences, women of color often face more pervasive and subtle barriers than their white counterparts. Their leadership strategies on how to address these insidious challenges, however, are rarely recorded. In this article, we give voice to these experiences

    Fetal Origins of Socioeconomic Inequalities in Early Childhood Health: the Generation R Study

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    The aim was to contribute to a further understanding of the origins of socioeconomic inequalities in child health, and, more in particular, of the possible role of intrauterine exposures in the genesis of these inequalities. Therefore, we studied socioeconomic inequalities, using maternal education as socioeconomic indicator, in 1) maternal health outcomes during pregnancy, 2) indicators of fetal growth, and 3) early childhood health outcomes. First, we found that women of low socioeconomic status (SES) have lower chances of completing a healthy pregnancy: they display more risk factors, such as psychosocial stress and smoking during pregnancy, and are more likely to develop preeclampsia, gestational hypertension and gestational diabetes. This may negatively affect health of the offspring. Our findings also have implications for these womenâ?Ts cardiovascular health, as they suggest an underlying increased cardiovascular risk that is manifested during pregnancy. Second, we found that fetal and early postnatal health is affected by motherâ?Ts socioeconomic status. Offspring of women of low SES grow more slowly in utero, grow faster in height during early childhood, and are more susceptible to upper respiratory tract infections compared with of

    Auto-conceito / auto-estima e vinculação nas relações de namoro em estudantes do ensino secundário

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    Comunicação apresentada no VII Simpósio Nacional de Investigação em Psicologia realizado na Universidade do Minho em Fev. 2010.As relações de namoro, enquanto relações de vinculação, assumem uma importância fulcral no processo de desenvolvimento, com implicações no auto-conceito e na auto-estima. Este estudo visa avaliar o auto-conceito e auto-estima dos adolescentes, bem como a sua relação amorosa numa perspectiva de vinculação. Pretendemos igualmente analisar a relação entre estas variáveis e dados de caracterização sócio-demográfica e da relação de namoro. A amostra é constituída por 149 estudantes do 10.º, 11.º e 12.º anos. Recorreu-se à Escala de Auto-Conceito e Auto-Estima (Peixoto & Almeida, 1999) para a avaliação do auto-conceito e da auto-estima. Para estudar as representações da vinculação de adolescentes ao par romântico utilizou-se o Questionário de Vinculação Amorosa (QVA) (Matos & Costa, 2001). Os dados obtidos permitiram constatar a existência de diferenças em dimensões específicas do auto-conceito em função do sexo dos estudantes. Verificaram-se associações significativas entre aspectos específicos do auto-conceito e a vinculação ao par romântico

    A double-blind randomized controlled trial of maternal postpartum deworming to improve infant weight gain in the Peruvian Amazon

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    Background : Nutritional interventions targeting the critical growth and development period before two years of age can have the greatest impact on health trajectories over the life course. Compelling evidence has demonstrated that interventions investing in maternal health in the first 1000 days of life are beneficial for both mothers and their children. One such potential intervention is deworming integrated into maternal postpartum care in areas where soil-transmitted helminth (STH) infections are endemic. Methodology/Principal Findings : From February to August 2014, 1010 mother-infant pairs were recruited into a trial aimed at assessing the effectiveness of maternal postpartum deworming on infant and maternal health outcomes. Following delivery, mothers were randomly assigned to receive either single-dose 400 mg albendazole or placebo. Participants were followed-up at 1 and 6 months postpartum. There was no statistically significant difference in mean weight gain between infants in the experimental and control groups (mean difference: -0.02; 95% CI: -0.1, 0.08) at 6 months of age. Further, deworming had no effect on measured infant morbidity indicators. However, ad hoc analyses restricted to mothers who tested positive for STHs at baseline suggest that infants of mothers in the experimental group had greater mean length gain in cm (mean difference: 0.8; 95% CI: 0.1, 1.4) and length-for-age z-score (mean difference: 0.5; 95% CI: 0.2, 0.8) at 6 months of age. Conclusions/Significance : In a study population composed of both STH-infected and uninfected mothers, maternal postpartum deworming was insufficient to impact infant growth and morbidity indicators up to 6 months postpartum. Among STH-infected mothers, however, important improvements in infant length gain and length-for-age were observed. The benefits of maternal postpartum deworming should be further investigated in study populations having higher overall prevalences and intensities of STH infections and, in particular, where whipworm and hookworm infections are of public health concern

    Memory Function and Brain Functional Connectivity Adaptations Following Multiple-Modality Exercise and Mind–Motor Training in Older Adults at Risk of Dementia: An Exploratory Sub-Study

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    © Copyright © 2020 Boa Sorte Silva, Nagamatsu, Gill, Owen and Petrella. Background: Multiple-modality exercise improves brain function. However, whether task-based brain functional connectivity (FC) following exercise suggests adaptations in preferential brain regions is unclear. The objective of this study was to explore memory function and task-related FC changes following multiple-modality exercise and mind–motor training in older adults with subjective cognitive complaints. Methods: We performed secondary analysis of memory function data in older adults [n = 127, mean age 67.5 (7.3) years, 71% women] randomized to an exercise intervention comprised of 45 min of multiple-modality exercise with additional 15 min of mind-motor training (M4 group, n = 63) or an active control group (M2 group, n = 64). In total, both groups exercised for 60 min/day, 3 days/week, for 24 weeks. We then conducted exploratory analyses of functional magnetic resonance imaging (fMRI) data collected from a sample of participants from the M4 group [n = 9, mean age 67.8 (8.8) years, 8 women] who completed baseline and follow-up task-based fMRI assessment. Four computer-based memory tasks from the Cambridge Brain Sciences cognitive battery (i.e. Monkey Ladder, Spatial Span, Digit Span, Paired Associates) were employed, and participants underwent 5 min of continuous fMRI data collection while completing the tasks. Behavioral data were analyzed using linear mixed models for repeated measures and paired-samples t-test. All fMRI data were analyzed using group-level independent component analysis and dual regression procedures, correcting for voxel-wise comparisons. Results: Our findings indicated that the M4 group showed greater improvements in the Paired Associates tasks compared to the M2 group at 24 weeks [mean difference: 0.47, 95% confidence interval (CI): 0.08 to 0.86, p = 0.019]. For our fMRI analysis, dual regression revealed significant decrease in FC co-activation in the right precentral/postcentral gyri after the exercise program during the Spatial Span task (corrected p = 0.008), although there was no change in the behavioral task performance. Only trends for changes in FC were found for the other tasks (all corrected p \u3c 0.09). In addition, for the Paired Associates task, there was a trend for increased co-activation in the right temporal lobe (Brodmann Area = 38, corrected p = 0.07), and left middle frontal temporal gyrus (corrected p = 0.06). Post hoc analysis exploring voxel FC within each group spatial map confirmed FC activation trends observed from dual regression. Conclusion: Our findings suggest that multiple modality exercise with mind–motor training resulted in greater improvements in memory compared to an active control group. There were divergent FC adaptations including significant decreased co-activation in the precentral/postcentral gyri during the Spatial Span task. Borderline significant changes during the Paired Associates tasks in FC provided insight into the potential of our intervention to promote improvements in visuospatial memory and impart FC adaptations in brain regions relevant to Alzheimer’s disease risk. Clinical Trial Registration: The trial was registered in ClinicalTrials.gov in April 2014, Identifier: NCT02136368

    Burnout syndrome in nursing professionals from urgency and emergency services

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    Objective: analyzing how scientific studies describe Burnout syndrome in nurses of urgent and emergency services. Method: an integrative literature review conducted by databases BDENF, IBECS, LILACS, MEDLINE and SciELO, through descriptors: burnout and nursing. From the 3087 selected publications for descriptors, only 11 articles met the criteria for inclusion and exclusion. Results: among the selected articles, 07 dealt with the stress; 04 spoke of the quality of life and leisure; 01 approached about somatic symptoms associated with Burnout and 03 detailing on Burnout syndrome, addressing the predictors and symptom dimensions in accordance with the Maslach Burnout Inventory. Conclusion: this study is important for population, professionals and managers acquire knowledge about the syndrome and may contribute to the development of coping strategies that will minimize the risk of triggering Burnout

    Efficacy of multivalent recombinant herpesvirus of turkey vaccines against high pathogenicity avian influenza, infectious bursal disease, and Newcastle disease viruses

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    Vaccines are an essential tool for the control of viral infections in domestic animals. We generated recombinant vector herpesvirus of turkeys (vHVT) vaccines expressing computationally optimized broadly reactive antigen (COBRA) H5 of avian influenza virus (AIV) alone (vHVT-AI) or in combination with virus protein 2 (VP2) of infectious bursal disease virus (IBDV) (vHVT-IBD-AI) or fusion (F) protein of Newcastle disease virus (NDV) (vHVT-ND-AI). In vaccinated chickens, all three vHVT vaccines provided 90–100% clinical protection against three divergent clades of high pathogenicity avian influenza viruses (HPAIVs), and significantly decreased number of birds and oral viral shedding titers at 2 days post-challenge compared to shams. Four weeks after vaccination, most vaccinated birds had H5 hemagglutination inhibition antibody titers, which significantly increased post-challenge. The vHVT-IBD-AI and vHVT-ND-AI vaccines provided 100% clinical protection against IBDVs and NDV, respectively. Our findings demonstrate that multivalent HVT vector vaccines were efficacious for simultaneous control of HPAIV and other viral infections.info:eu-repo/semantics/publishedVersio

    Ingestion of microplastics by the chironomid Chironomus sancticaroli and effects on the microbiome in the presence of PBDEs

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    Microplastic particles in the environment can associate with persistent organic pollutants (POPs) due to the hydrophobic nature of plastics and organic chemicals. PBDEs (polybrominated diphenyl ethers) are widely used as flame-retardants in products such as textiles and soft furnishings, with the potential to leach into the environment and be associated with microplastics. If ingested, the gut environment of an organism may favour desorption of adsorbed chemicals due to gut condition. Therefore the ingestion of microplastic particles has implications for uptake and bioaccumulation of these chemicals. Furthermore the presence of microplastics and chemicals in the gut of an organism can also influence the gut environment itself. Gut microbiomes are known to hold a vital role in host metabolism, nutrition and immunity and as such understanding the influence of chemicals and microplastics on the gut microbiota is key

    Emission-line stars discovered in the UKST H-alpha survey of the Large Magellanic Cloud; Part 1: Hot stars

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    We present new, accurate positions, spectral classifications, radial and rotational velocities, H-alpha fluxes, equivalent widths and B,V,I,R magnitudes for 579 hot emission-line stars (classes B0 - F9) in the Large Magellanic Cloud which include 469 new discoveries. Candidate emission line stars were discovered using a deep, high resolution H-alpha map of the central 25 deg2 of the LMC obtained by median stacking a dozen 2 hour H-alpha exposures taken with the UK Schmidt Telescope. Spectroscopic follow-up observations on the AAT, UKST, VLT, the SAAO 1.9m and the MSSSO 2.3m telescope have established the identity of these faint sources down to magnitude R~23 for H-alpha (4.5 x 10^-17 ergs cm^2 s^-1 Ang). Confirmed emission-line stars have been assigned an underlying spectral classification through cross-correlation against 131 absorption line template spectra covering the range O1 to F8. We confirm 111 previously identified emission line stars and 64 previously known variable stars with spectral types hotter than F8. The majority of hot stars identified (518 stars or 89%) are class B. Of all the hot emission-line stars in classes B-F, 130 or 22% are type B[e], characterised by the presence of forbidden emission lines such as [SII], [NII] and [OII]. We report on the physical location of these stars with reference to possible contamination from ambient HII emission. Along with flux calibration of the H-alpha emission we provide the first H-alpha luminosity function for selected sub-samples after correction for any possible nebula or ambient contamination. We find a moderate correlation between the intensity of H-alpha emission and the V magnitude of the central star based on SuperCOSMOS magnitudes and OGLE-II photometry where possible. Cool stars from classes G-S, with and without strong H-alpha emission, will be the focus of part 2 in this series.Comment: 24 pages (main paper) 36 figures, 6 tables; Appendix Tables: 22 pages, MNRAS, 201
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