144 research outputs found

    The impact of changing nonimmigrant visa policies on international students’ psychological adjustment and well-being in the United States during the COVID-19 pandemic: a qualitative study

    Get PDF
    Background Since the Immigration and Nationality Act of 1952, the number of international students in the United States had been gradually increasing. However, the total numbers have begun to decrease since 2019–2020 school year due to the Trump administration\u27s policy and COVID-19. Still, little is known about how international students’ psychological adjustment and well-being have been affected by changing nonimmigrant visa policy and the COVID-19 pandemic. Methods We conducted a total of 34 online semi-structured in-depth interviews with international students from 18 countries of origin studying in the San Francisco Bay Area, California. More than 60% of the participants (21 out of 34) were aged 21 to 25. Among our 34 participants, gender and 18 were male and 16 were female, and 19 were undergraduate students and 15 were master’s students. The majority of the participants were first-generation college students (22/34, 64.71%). Verbatim transcription was done for all interviews. NVivo was used for both deductive and inductive approaches to the qualitative analysis. Results Overall, the recent political climate negatively impacted participants’ psychology of adjustment and well-being. July 6, 2020 Policy Directive for international students caused severe uncertainty about whether they can continue studying in the United States. There were many resources or services needed to overcome this period, such as extended mental and emotional support from the counseling services as well as financial and informational support from the international student office and university. Although international students had the benefit of the university\u27s food assistance program, they were not eligible to receive any external support outside of the university and financial aid at the local and federal levels. Whether maintaining F-1 visa status was one of their major concerns. Due to COVID-19, job opportunities were limited, which made international students difficult to obtain Curricular Practical Training (CPT) and secure a job in the United States within the 90-day unemployment limit of Optical Practical Training (OPT). H-1B visa and permanent residency were other challenges to go through, but participants saw positive perspectives from the Biden administration. Conclusions Uncertain policy changes due to COVID-19 and presidential transitions impacted international students’ psychological well-being and adjustment. International students are important populations in the United States who have supported jobs that are high in demand and economically contributed to the United States. It is expected that future policies at various levels support international students’ life and improve their health equity and mental health

    The impact of COVID-19 and anti-immigration policy on an undocumented student in the United States: a qualitative case study

    Get PDF
    Background The change of Deferred Action for Childhood Arrivals (DACA) program has significantly impacted DACA students’ mental health in the United States. The study aimed to conduct a qualitative case study for understanding the effects of DACA program on one undocumented college student’s life during the COVID-19 pandemic. Methods We conducted a two-component qualitative case study, the online survey and the subsequent in-depth interview, with a DACA college student, Leah (pseudonym), in California who was in an ongoing fear of deportation before and during the COVID-19 pandemic. We used Questionnaire-9 (PHQ-9) and General Anxiety Disorder-7 (GAD-7) in the online survey to measure her level of depression and anxiety. QSR NVivo was used to analyze the verbatim transcription. Results Leah’s anxiety and depression level just before the Supreme Court’s decision to the DACA termination in June 2020 was higher than during the COVID-19 pandemic in 2021. Leah’s concern still remained due to the uncertain legal status in the United States even after the presidential election. Conclusions During 2020-2022, the anti-immigration policy, the COVID-19 pandemic, and the presidential election has impacted a DACA student’s mental health status. However, because of the unstable legal status and fear of deportation in the United States, our participant’s anxiety and depression level maintained high. From our participant’s standpoint, more policy support is needed to sustain her legal status, financial stability, and mental health during the pandemic

    The impact of COVID-19 and anti-immigration policy on an undocumented student in the United States: a qualitative case study

    Get PDF
    # Background The change of Deferred Action for Childhood Arrivals (DACA) program has significantly impacted DACA students' mental health in the United States. The study aimed to conduct a qualitative case study for understanding the effects of DACA program on one undocumented college student's life during the COVID-19 pandemic. # Methods We conducted a two-component qualitative case study, the online survey and the subsequent in-depth interview, with a DACA college student, Leah (pseudonym), in California who was in an ongoing fear of deportation before and during the COVID-19 pandemic. We used Questionnaire-9 (PHQ-9) and General Anxiety Disorder-7 (GAD-7) in the online survey to measure her level of depression and anxiety. QSR NVivo was used to analyze the verbatim transcription. # Results Leah's anxiety and depression level just before the Supreme Court's decision to the DACA termination in June 2020 was higher than during the COVID-19 pandemic in 2021. Leah's concern still remained due to the uncertain legal status in the United States even after the presidential election. # Conclusions During 2020-2022, the anti-immigration policy, the COVID-19 pandemic, and the presidential election has impacted a DACA student's mental health status. However, because of the unstable legal status and fear of deportation in the United States, our participant's anxiety and depression level maintained high. From our participant's standpoint, more policy support is needed to sustain her legal status, financial stability, and mental health during the pandemic

    Improving drought and salinity tolerance in barley by application of salicylic acid and potassium nitrate

    Get PDF
    AbstractGrowth and physiological activities of barley (Hordeum vulgare L. cv. Gustoe) grown in soil cultures were evaluated to recognize the ameliorative role of salicylic acid (SA) and KNO3 against the negative effects of salt and water deficit stresses. Barley plants were subjected to three levels of NaCl (50, 100 and 150mM), three levels of water stress (80%, 70% and 50% of the soil water content (SWC) and the combination of 150mM NaCl+50μM SA, 150mM NaCl+10mM KNO3, 50% SWC+50μM SA and 50% SWC+10mM KNO3 for two weeks. Salt and water deficit stresses reduced the shoot growth, leaf photosynthetic pigments, K+ contents and provoked oxidative stress in leaves confirmed by considerable changes in soluble carbohydrate, proline, malondialdehyde (MDA), total phenolic compounds, antioxidant activity and Na+ contents. Leaf soluble protein of salt and water deficit treated plants was unaffected. The Na+/K+ ratio increased with increasing salt and water deficit treated plants. Application of 50μM SA or 10mM KNO3 to150mM NaCl and/or 50% SWC treated plants improved these attributes under salt and water stresses. Soluble carbohydrates in stressed plants may have a significant role in osmotic adjustment. It can be concluded that the addition of SA or KNO3 can ameliorate the oxidative stress in barley stressed plants. This ameliorative effect might be maintained through low MDA contents and decreased Na+/K+ ratio in leaves. This study also provided evidence for the ability of barley cultivation in salt and water deficit soils due to its capacity for osmotic adjustment

    Langerhans cell histiocytosis of the sternum

    Get PDF
    We report a rare case of Langerhans cell histiocytosis involving the sternum. The patient was a 12-year-old girl presenting with anterior chest pain and swelling. Radiographs and computed tomography showed an osteolytic lesion in the sternum. Technetium bone scintigraphy revealed increased uptakes in the sternum, the greater trochanter of the right femur, and the right distal tibia. Incisional biopsy for the sternum lesion was performed, and the histopathologic diagnosis was Langerhans cell histiocytosis. She was treated with chemotherapy and the symptoms disappeared

    Two transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon

    Get PDF
    Because iron toxicity and deficiency are equally life threatening, maintaining intracellular iron levels within a narrow optimal range is critical for nearly all known organisms. However, regulatory mechanisms that establish homeostasis are not well understood in organisms that dwell in environments at the extremes of pH, temperature, and salinity. Under conditions of limited iron, the extremophile Halobacterium salinarum, a salt-loving archaeon, mounts a specific response to scavenge iron for growth. We have identified and characterized the role of two transcription factors (TFs), Idr1 and Idr2, in regulating this important response. An integrated systems analysis of TF knockout gene expression profiles and genome-wide binding locations in the presence and absence of iron has revealed that these TFs operate collaboratively to maintain iron homeostasis. In the presence of iron, Idr1 and Idr2 bind near each other at 24 loci in the genome, where they are both required to repress some genes. By contrast, Idr1 and Idr2 are both necessary to activate other genes in a putative a feed forward loop. Even at loci bound independently, the two TFs target different genes with similar functions in iron homeostasis. We discuss conserved and unique features of the Idr1–Idr2 system in the context of similar systems in organisms from other domains of life

    Financing renewable energy: Who is financing what and why it matters

    Get PDF
    Successful financing of innovation in renewable energy (RE) requires a better understanding of the relationship between different types of finance and their willingness to invest in RE. We study the ‘direction’ of innovation that financial actors create. Focusing on the deployment phase of innovation, we use Bloomberg New Energy Finance (BNEF) data to construct a global dataset of RE asset finance flows from 2004 to 2014. We analyze the asset portfolios of different RE technologies financed by different financial actors according to their size, skew and level of risk. We use entropy-based indices to measure skew, and construct a heuristic index of risk that varies with the technology, time, and country of investment to measure risk. We start by comparing the behavior of private and public types of finance and then disaggregate further along 11 different financial actors (e.g. private banks, public banks, and utilities) and 11 types of RE technologies that are invested in (e.g. different kinds of power generation from solar radiation, wind or biomass). Financial actors vary considerably in the composition of their investment portfolio, creating directions towards particular technologies. Public financial actors invest in portfolios with higher risk technologies, also creating a direction; they also increased their share in total investment dramatically over time. We use these preliminary results to formulate new research questions about how finance affects the directionality of innovation, and the implications for RE policies

    Genome-Wide Association Data Reveal a Global Map of Genetic Interactions among Protein Complexes

    Get PDF
    This work demonstrates how gene association studies can be analyzed to map a global landscape of genetic interactions among protein complexes and pathways. Despite the immense potential of gene association studies, they have been challenging to analyze because most traits are complex, involving the combined effect of mutations at many different genes. Due to lack of statistical power, only the strongest single markers are typically identified. Here, we present an integrative approach that greatly increases power through marker clustering and projection of marker interactions within and across protein complexes. Applied to a recent gene association study in yeast, this approach identifies 2,023 genetic interactions which map to 208 functional interactions among protein complexes. We show that such interactions are analogous to interactions derived through reverse genetic screens and that they provide coverage in areas not yet tested by reverse genetic analysis. This work has the potential to transform gene association studies, by elevating the analysis from the level of individual markers to global maps of genetic interactions. As proof of principle, we use synthetic genetic screens to confirm numerous novel genetic interactions for the INO80 chromatin remodeling complex

    Active, but not passive cigarette smoking was inversely associated with mammographic density

    Get PDF
    The opposing carcinogenic and antiestrogenic properties of tobacco smoke may explain why epidemiologic studies have not consistently reported positive associations for active smoking and breast cancer risk. A negative relation between mammographic density, a strong breast cancer risk factor, and active smoking would lend support for an antiestrogenic mechanism. We used multivariable linear regression to assess the associations of active smoking and secondhand smoke (SHS) exposure with mammographic density in 799 pre- and early perimenopausal women in the Study of Women’s Health Across the Nation (SWAN). We observed that current active smoking was associated with 7.2% lower mammographic density, compared to never active smoking and no SHS exposure (p = 0.02). Starting to smoke before 18 years of age and having smoked ≥20 cigarettes/day were also associated with statistically significantly lower percent densities. Among nulliparous women having smoked ≥20 cigarettes/day was associated with 23.8% lower density, compared to having smoked ≤9 cigarettes/day (p < 0.001). Our findings support the hypothesis that tobacco smoke exerts an antiestrogenic effect on breast tissue, but counters the known increased risk of breast cancer with smoking prior to first full-term birth. Thus, our data suggest that the antiestrogenic but not the carcinogenic effects of smoking may be reflected by breast density
    corecore