A Standardized Approach for Measuring the Quality of Urban Life in New Urban Communities Case Study: New Damietta City, Egypt

New urban communities aim to achieve a clear societal vision through the promotion of urban development and improving their efficiency to suit human life with its various requirements. Therefore, the quality of life standards can be adopted to reflect their indicators positively on individuals and communities under their organizational, development strategies, and development plans that are leading to the Egyptian society’s prosperity. In this context, the aim of the research is to investigate and analyse the quality of urban life with the identification of its effective and efficient indicators for the study area. Furthermore, the research intends to provide a methodology to measure the quality of urban life of New Damietta City in Egypt, and to test the level of its residents\u27 satisfaction through conducting a field survey targeting the satisfaction of the city’s residents, based on a comprehensive questionnaire including the related quality of urban life indicators. The researchers provided statistical analysis by using SPSS software, in which the questionnaire data is processed, and the results are obtained as numerically accurate rates for each quality of urban life index. Drawing upon these results, the researchers concluded that by the implementation of the quality of urban life indicators proved to be an effective approach to improve the resident’s needs in new urban communities and to set coordination presses between their involving stakeholders

Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic

Introduction Childhood cancer is a leading cause of death. It is unclear whether the COVID-19 pandemic has impacted childhood cancer mortality. In this study, we aimed to establish all-cause mortality rates for childhood cancers during the COVID-19 pandemic and determine the factors associated with mortality. Methods Prospective cohort study in 109 institutions in 41 countries. Inclusion criteria: children <18 years who were newly diagnosed with or undergoing active treatment for acute lymphoblastic leukaemia, non-Hodgkin's lymphoma, Hodgkin lymphoma, retinoblastoma, Wilms tumour, glioma, osteosarcoma, Ewing sarcoma, rhabdomyosarcoma, medulloblastoma and neuroblastoma. Of 2327 cases, 2118 patients were included in the study. The primary outcome measure was all-cause mortality at 30 days, 90 days and 12 months. Results All-cause mortality was 3.4% (n=71/2084) at 30-day follow-up, 5.7% (n=113/1969) at 90-day follow-up and 13.0% (n=206/1581) at 12-month follow-up. The median time from diagnosis to multidisciplinary team (MDT) plan was longest in low-income countries (7 days, IQR 3-11). Multivariable analysis revealed several factors associated with 12-month mortality, including low-income (OR 6.99 (95% CI 2.49 to 19.68); p<0.001), lower middle income (OR 3.32 (95% CI 1.96 to 5.61); p<0.001) and upper middle income (OR 3.49 (95% CI 2.02 to 6.03); p<0.001) country status and chemotherapy (OR 0.55 (95% CI 0.36 to 0.86); p=0.008) and immunotherapy (OR 0.27 (95% CI 0.08 to 0.91); p=0.035) within 30 days from MDT plan. Multivariable analysis revealed laboratory-confirmed SARS-CoV-2 infection (OR 5.33 (95% CI 1.19 to 23.84); p=0.029) was associated with 30-day mortality. Conclusions Children with cancer are more likely to die within 30 days if infected with SARS-CoV-2. However, timely treatment reduced odds of death. This report provides crucial information to balance the benefits of providing anticancer therapy against the risks of SARS-CoV-2 infection in children with cancer

The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study

Aim The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery. Methods This was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin. Results Overall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P < 0.001). After adjustment, delay was not associated with a lower rate of complete resection (OR 1.18, 95% CI 0.90-1.55, P = 0.224), which was consistent in elective patients only (OR 0.94, 95% CI 0.69-1.27, P = 0.672). Longer delays were not associated with poorer outcomes. Conclusion One in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Institutionalisierung von Nachhaltigkeitsgovernance: Wie werden Prozesse zur Etablierung nachhaltiger Hochschulen in Deutschland gestaltet?

Die steigende Relevanz von Nachhaltigkeit, bedingt durch den Klimawandel und die damit verbundenen Herausforderungen, macht deutlich, dass Nachhaltigkeit in all ihren Dimensionen ‒ ökologisch, ökonomisch und sozial ‒ kein Thema nur für Klimaaktivist*innen ist, sondern eine globale Aufgabe für alle Akteur*innen darstellt. Insbesondere Hochschulen spielen dabei eine unabdingbare Rolle, da sie als Wissenschaftsorganisationen faktengestützte Erkenntnisse produzieren, die als Grundlage für eine Transformation hin zu Nachhaltigkeit dienen. Angesichts dessen müssen Hochschulen die Bedeutung der Nachhaltigkeit im eigenen Alltag immer mehr berücksichtigen, indem sie Elemente der Nachhaltigkeitsgovernance in ihre Strukturen verankern. Die vorliegende Arbeit zielt darauf ab, den aktuellen Stand der Nachhaltigkeitsgovernance an Hochschulen in Deutschland durch eine qualitative Forschung tiefgehend zu erforschen. Die Studie, die auf Interviews mit internen Stakeholdern aus verschiedenen Universitäten basiert, strebt danach, den Ist-Zustand zu erfassen. Die Ergebnisse der vorliegenden Arbeit zeigen, dass trotz bereits vorhandener Nachhaltigkeitsstrukturen in vielen Bereichen Defizite in der Umsetzung bestehen. Diskrepanzen in der Wahrnehmung und Umsetzung von Nachhaltigkeitszielen unter-streichen die Notwendigkeit einer umfassenderen Integration von Nachhaltigkeit in alle Bereiche des Hochschulsystems. Die vorliegende Arbeit trägt durch die Bereitstellung von Einblicken in bestehende Praktiken zur Weiterentwicklung der Nachhaltigkeitsgovernance an Hochschulen bei.Driven by climate change and associated challenges, sustainability's relevance becomes more obvious. Accordingly, sustainability in all its dimensions ‒ ecological, economic, and social ‒ is no longer solely a concern for so-called climate activists but rather a global issue for all related stakeholders. In particular, universities play an essential role in this regard. As scientific organizations, they produce evidence-based knowledge serving as a motor for a societal transformation towards sustainability. Consequently, universities must increasingly consider sustainability in their daily operations by embedding elements of sustainability governance into their structures. This dissertation aims to provide an in-depth exploration of the current state of sustainability governance at higher education institutions in Germany. Employing qualitative research based on interviews with stakeholders from various universities, this study seeks to capture status without preconceived assumptions or hypothesis. The findings of this study reveal that despite the existence of sustainability structures in many areas, there are deficits in implementation. Discrepancies in the perception and implementation of sustainability objectives highlight the necessity for a comprehensive integration of sustainability across all areas of the university system. By providing insights into existing practices, this study contributes to the progress of sustainability governance at universities

The Prevalence of Atherosclerosis and Related Factors in Both Types of Premature Ejaculation (Acquired and Lifelong) in Men

Abstract Background: investigate the prevalence and The related factors between the two types of premature ejaculation (lifelong PE[LPE], acquired PE [APE] in men and atherosclerosis. Methods: One hundred patients complaining of PE and 100 control subjects were enrolled in this prospective study.All cases underwent a full medical history and Clinical examination.Blood pressure,serum lipid profile, testosterone,and Body mass index (BMI) were measured.The Arabic index of premature ejaculation (AIPE) and self-estimated (IELT) Intravaginal latency time was used for PE evaluation. Atherosclerosis was diagnosed by measuring the Carotid artery intima-media thickness (CIMT). Patients were divided into two major groups, (Group 1) [PE group] and (Group 2) [Control group]. Results: The mean age of cases in (group1) and (group 2) were 44.5 ± 11.7 versus 42.3 ± 10.8 yrs. The Systolic BP, diastolic (BP), Serum Triglycerides, serum LDL (BMI), the prevalence of atherosclerosis and smoking rate showed higher results in (group1) compared to group2, with significant difference (p&lt;0.001). The IELT was significantly lower in group1 (2.67± 1.25) compared to group2 (3.77±1.52), (p&lt;0.001). The prevalence of APE (74%) was significantly higher than LPE (26%) in group1(p&lt;0.001). regression analysis revealed that patients with APE showed more comorbidities than LPE patients concerning the prevalence of atherosclerosis, hypertension, and hyperlipidemia (p&lt;0.001 for all items).Both of APE and LPE were significantly related to age&gt;35y, BMI ≥ 25 kg/m2, smoking, Bl pressure and hyperlipidemia (p&lt;0.001 for all factors).Conclusions: Both types of PE,predominately the APE type,are associated with atherosclerosis, hypertension, and hyperlipidemia. The APE type reported more prevalence than the LPE.</jats:p