55 research outputs found
2006 SQ372: A Likely Long-Period Comet from the Inner Oort Cloud
We report the discovery of a minor planet (2006 SQ372) on an orbit with a
perihelion of 24 AU and a semimajor axis of 796 AU. Dynamical simulations show
that this is a transient orbit and is unstable on a timescale of 200 Myrs.
Falling near the upper semimajor axis range of the scattered disk and the lower
semimajor axis range of the Oort Cloud, previous membership in either class is
possible. By modeling the production of similar orbits from the Oort Cloud as
well as from the scattered disk, we find that the Oort Cloud produces 16 times
as many objects on SQ372-like orbits as the scattered disk. Given this result,
we believe this to be the most distant long-period comet ever discovered.
Furthermore, our simulation results also indicate that 2000 OO67 has had a
similar dynamical history. Unaffected by the "Jupiter-Saturn Barrier," these
two objects are most likely long-period comets from the inner Oort Cloud
Galactic Globular and Open Clusters in the Sloan Digital Sky Survey. I. Crowded Field Photometry and Cluster Fiducial Sequences in ugriz
We present photometry for globular and open cluster stars observed with the
Sloan Digital Sky Survey (SDSS). In order to exploit over 100 million stellar
objects with r < 22.5 mag observed by SDSS, we need to understand the
characteristics of stars in the SDSS ugriz filters. While star clusters provide
important calibration samples for stellar colors, the regions close to globular
clusters, where the fraction of field stars is smallest, are too crowded for
the standard SDSS photometric pipeline to process. To complement the SDSS
imaging survey, we reduce the SDSS imaging data for crowded cluster fields
using the DAOPHOT/ALLFRAME suite of programs and present photometry for 17
globular clusters and 3 open clusters in a SDSS value-added catalog. Our
photometry and cluster fiducial sequences are on the native SDSS 2.5-meter
ugriz photometric system, and the fiducial sequences can be directly applied to
the SDSS photometry without relying upon any transformations. Model photometry
for red giant branch and main-sequence stars obtained by Girardi et al. cannot
be matched simultaneously to fiducial sequences; their colors differ by
~0.02-0.05 mag. Good agreement (< ~0.02 mag in colors) is found with Clem et
al. empirical fiducial sequences in u'g'r'i'z' when using the transformation
equations in Tucker et al.Comment: 30 pages, 25 figures. Accepted for publication in ApJS. Version with
high resolution figures available at
http://www.astronomy.ohio-state.edu/~deokkeun/AnJohnson.pd
Pulsed Gamma Rays from the Original Millisecond and Black Widow Pulsars: a case for Caustic Radio Emission?
We report the detection of pulsed gamma-ray emission from the fast
millisecond pulsars (MSPs) B1937+21 (also known as J1939+2134) and B1957+20
(J1959+2048) using 18 months of survey data recorded by the \emph{Fermi} Large
Area Telescope (LAT) and timing solutions based on radio observations conducted
at the Westerbork and Nan\c{c}ay radio telescopes. In addition, we analyzed
archival \emph{RXTE} and \emph{XMM-Newton} X-ray data for the two MSPs,
confirming the X-ray emission properties of PSR B1937+21 and finding evidence
() for pulsed emission from PSR B1957+20 for the first time. In
both cases the gamma-ray emission profile is characterized by two peaks
separated by half a rotation and are in close alignment with components
observed in radio and X-rays. These two pulsars join PSRs J0034-0534 and
J2214+3000 to form an emerging class of gamma-ray MSPs with phase-aligned peaks
in different energy bands. The modeling of the radio and gamma-ray emission
profiles suggests co-located emission regions in the outer magnetosphere.Comment: Accepted for publication in the Astrophysical Journa
On the relative importance of thermal and chemical buoyancy in regular and impact-induced melting in a Mars-like planet
We ran several series of two-dimensional numerical mantle convection
simulations representing in idealized form the thermochemical evolution of a
Mars-like planet. In order to study the importance of compositional buoyancy of
melting mantle, the models were set up in pairs of one including all thermal
and compositional contributions to buoyancy and one accounting only for the
thermal contributions. In several of the model pairs, single large impacts were
introduced as causes of additional strong local anomalies, and their evolution
in the framework of the convecting mantle was tracked. The models confirm that
the additional buoyancy provided by the depletion of the mantle by regular
melting can establish a global stable stratification of the convecting mantle
and throttle crust production. Furthermore, the compositional buoyancy is
essential in the stabilization and preservation of local compositional
anomalies directly beneath the lithosphere and offers a possible explanation
for the existence of distinct, long-lived reservoirs in the martian mantle. The
detection of such anomalies by geophysical means is probably difficult,
however; they are expected to be detected by gravimetry rather than by seismic
or heat flow measurements. The results further suggest that the crustal
thickness can be locally overestimated by up to ~20 km if impact-induced
density anomalies in the mantle are neglected.Comment: 29 pages, 10 figure
First-Year Spectroscopy for the SDSS-II Supernova Survey
This paper presents spectroscopy of supernovae discovered in the first season
of the Sloan Digital Sky Survey-II Supernova Survey. This program searches for
and measures multi-band light curves of supernovae in the redshift range z =
0.05 - 0.4, complementing existing surveys at lower and higher redshifts. Our
goal is to better characterize the supernova population, with a particular
focus on SNe Ia, improving their utility as cosmological distance indicators
and as probes of dark energy. Our supernova spectroscopy program features
rapid-response observations using telescopes of a range of apertures, and
provides confirmation of the supernova and host-galaxy types as well as precise
redshifts. We describe here the target identification and prioritization, data
reduction, redshift measurement, and classification of 129 SNe Ia, 16
spectroscopically probable SNe Ia, 7 SNe Ib/c, and 11 SNe II from the first
season. We also describe our efforts to measure and remove the substantial host
galaxy contamination existing in the majority of our SN spectra.Comment: Accepted for publication in The Astronomical Journal(47pages, 9
figures
Psychosocial correlates of dietary fat intake in African-American adults: a cross-sectional study
<p>Abstract</p> <p>Background</p> <p>Current dietary guidelines recommend that dietary fat should comprise 20â35% percent of total energy intake, with less than 10% of energy from saturated fat. However, many Americans exceed these goals and data suggest that African Americans tend to consume a higher percentage of energy from dietary fat than Whites. Because diets low in dietary fat, particularly saturated fat, are associated with lower risk for many chronic illnesses, it is important to identify strategies to reduce high fat intakes. This study examined associations of psychosocial factors with dietary fat intake in African American adults 18 to 70 years.</p> <p>Methods</p> <p>Data are self-reported from a cross-sectional survey of African Americans (n = 658) using an 11-page questionnaire, collected from June to October 2003. Associations of psychosocial (predisposing, reinforcing, and enabling) factors based on the PRECEDE framework, dietary fat-related behaviors, and participant characteristics (e.g., age, sex, education, BMI) with total and saturated fat consumption are described using linear regression and analysis of variance.</p> <p>Results</p> <p>The mean age of participants was 43.9 years, 57% were female, 37% were college graduates, and 76% were overweight/obese. Respondents with lower fat intakes were female, older, had high education and very good/excellent perceived health. Among the psychosocial factors, the strongest (inverse) associations with fat intake were with two predisposing factors: <it>belief in the importance of a low-fat diet </it>(both genders) and <it>high self-efficacy </it>(women only). Fat intake was also significantly lower among participants who could <it>count on those close for encouragement to eat healthy foods </it>(a reinforcing factor) and among men who <it>needed more information about preparing healthy foods </it>(an enabling factor).</p> <p>Conclusion</p> <p>Dietary interventions to decrease fat intake in African American adults may benefit from incorporating predisposing factors, such as personal beliefs and self-efficacy, in their design and implementation.</p
The Seventh Data Release of the Sloan Digital Sky Survey
This paper describes the Seventh Data Release of the Sloan Digital Sky Survey
(SDSS), marking the completion of the original goals of the SDSS and the end of
the phase known as SDSS-II. It includes 11663 deg^2 of imaging data, with most
of the roughly 2000 deg^2 increment over the previous data release lying in
regions of low Galactic latitude. The catalog contains five-band photometry for
357 million distinct objects. The survey also includes repeat photometry over
250 deg^2 along the Celestial Equator in the Southern Galactic Cap. A
coaddition of these data goes roughly two magnitudes fainter than the main
survey. The spectroscopy is now complete over a contiguous area of 7500 deg^2
in the Northern Galactic Cap, closing the gap that was present in previous data
releases. There are over 1.6 million spectra in total, including 930,000
galaxies, 120,000 quasars, and 460,000 stars. The data release includes
improved stellar photometry at low Galactic latitude. The astrometry has all
been recalibrated with the second version of the USNO CCD Astrograph Catalog
(UCAC-2), reducing the rms statistical errors at the bright end to 45
milli-arcseconds per coordinate. A systematic error in bright galaxy photometr
is less severe than previously reported for the majority of galaxies. Finally,
we describe a series of improvements to the spectroscopic reductions, including
better flat-fielding and improved wavelength calibration at the blue end,
better processing of objects with extremely strong narrow emission lines, and
an improved determination of stellar metallicities. (Abridged)Comment: 20 pages, 10 embedded figures. Accepted to ApJS after minor
correction
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19
IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19.
Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19.
DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 nonâcritically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022).
INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (nâ=â257), ARB (nâ=â248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; nâ=â10), or no RAS inhibitor (control; nâ=â264) for up to 10 days.
MAIN OUTCOMES AND MEASURES The primary outcome was organ supportâfree days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes.
RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ supportâfree days among critically ill patients was 10 (â1 to 16) in the ACE inhibitor group (nâ=â231), 8 (â1 to 17) in the ARB group (nâ=â217), and 12 (0 to 17) in the control group (nâ=â231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ supportâfree days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively).
CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes.
TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570
- âŠ