Quasar candidates selection in the Virtual Observatory era

We present a method for the photometric selection of candidate quasars in multiband surveys. The method makes use of a priori knowledge derived from a subsample of spectroscopic confirmed QSOs to map the parameter space. The disentanglement of QSOs candidates and stars is performed in the colour space through the combined use of two algorithms, the Probabilistic Principal Surfaces and the Negative Entropy clustering, which are for the first time used in an astronomical context. Both methods have been implemented in the VONeural package on the Astrogrid VO platform. Even though they belong to the class of the unsupervised clustering tools, the performances of the method are optimized by using the available sample of confirmed quasars and it is therefore possible to learn from any improvement in the available "base of knowledge". The method has been applied and tested on both optical and optical plus near infrared data extracted from the visible SDSS and infrared UKIDSS-LAS public databases. In all cases, the experiments lead to high values of both efficiency and completeness, comparable if not better than the methods already known in the literature. A catalogue of optical candidate QSOs extracted from the SDSS DR7 Legacy photometric dataset has been produced and is publicly available at the URL voneural.na.infn.it/qso.html.Comment: 75 pages, 43 figure, 7 tables, accepted for publication in MNRA

Effects of polymer polydispersity on the phase behaviour of colloid-polymer mixtures

We study the equilibrium behaviour of a mixture of monodisperse hard sphere colloids and polydisperse non-adsorbing polymers at their $\theta$-point, using the Asakura-Oosawa model treated within the free-volume approximation. Our focus is the experimentally relevant scenario where the distribution of polymer chain lengths across the system is fixed. Phase diagrams are calculated using the moment free energy method, and we show that the mean polymer size $\xi_{\rm c}$ at which gas-liquid phase separation first occurs decreases with increasing polymer polydispersity $\delta$. Correspondingly, at fixed mean polymer size, polydispersity favours gas-liquid coexistence but delays the onset of fluid-solid separation. On the other hand, we find that systems with different $\delta$ but the same {\em mass-averaged} polymer chain length have nearly polydispersity-independent phase diagrams. We conclude with a comparison to previous calculations for a semi-grandcanonical scenario, where the polymer chemical potentials are imposed, which predicted that fluid-solid coexistence was over gas-liquid in some areas of the phase diagram. Our results show that this somewhat counter-intuitive result arose because the actual polymer size distribution in the system is shifted to smaller sizes relative to the polymer reservoir distribution.Comment: Changes in v2: sketch in Figure 1 corrected, other figures improved; added references to experimental work and discussion of mapping from polymer chain length to effective radiu

Exploring the effectiveness of the output-based aid voucher program to increase uptake of gender-based violence recovery services in Kenya: a qualitative evaluation

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Background: Few studies in Africa have explored in detail the ability of output-based aid (OBA) voucher programs to increase access to gender-based violence recovery (GBVR) services. Methods: A qualitative study was conducted in 2010 and involved: (i) in-depth interviews (IDIs) with health managers, service providers, voucher management agency (VMA) managers and (ii) focus group discussions (FGDs) with voucher users, voucher non-users, voucher distributors and opinion leaders drawn from five program sites in Kenya. Results: The findings showed promising prospects for the uptake of OBA GBVR services among target population. However, a number of factors affect the uptake of the services. These include lack of general awareness of the GBVR services vouchers, lack of understanding of the benefit package, immediate financial needs of survivors, as well as stigma and cultural beliefs that undermine reporting of cases or seeking essential medical services. Moreover, accreditation of only hospitals to offer GBVR services undermines access to the services in rural areas. Poor responsiveness from law enforcement agencies and fear of reprisal from perpetrators also undermine treatment options and access to medical services. Low provider knowledge on GBVR services and lack of supplies also affect effective provision and management of GBVR services. Conclusions: The above findings suggest that there is a need to build the capacity of health care providers and police officers, strengthen the community strategy component of the OBA program to promote the GBVR services voucher, and conduct widespread community education programs aimed at prevention, ensuring survivors know how and where to access services and addressing stigma and cultural barriers.The Bill and Melinda Gates Foundatio

Spectroscopic characterization of 78 DENIS ultracool dwarf candidates in the solar neighborhood and the Upper Sco OB association

Aims: Low-resolution optical spectroscopic observations for 78 very low-mass star and brown dwarf candidates that have been photometrically selected using the DENIS survey point source catalogue. Methods: Spectral types are derived for them using measurements of the PC3 index. They range from M6 to L4. H_alpha emission and NaI subordinate doublet (818.3 nm and 819.9 nm) equivalent widths are measured in the spectra. Spectroscopic indices of TiO, VO, CrH and FeH molecular features are also reported. Results: A rule-of-thumb criterion to select young very low-mass objects using the NaI doublet equivalent width is given. It is used to confirm seven new members of the Upper Sco OB association and two new members of the R Cr-A star-forming region. Four of our field objects are also classified as very young, but are not members of any known nearby young association. The frequency of lower-gravity young objects in our field ultracool sample is 8.5%. Our results provide the first spectroscopic classification for 38 ultracool dwarfs in the solar vicinity with spectrophotometric distances in the range 17 pc to 65 pc (3 of them are new L dwarfs within 20 pc).Comment: 25 pages, 10 figures, 7 tables, Accepted by A&

The intriguing HI gas in NGC 5253: an infall of a diffuse, low-metallicity HI cloud?

(Abridged) We present new, deep HI line and 20-cm radio continuum data of the very puzzling blue compact dwarf galaxy NGC 5253, obtained with the ATCA as part of the `Local Volume HI Survey' (LVHIS). Our low-resolution HI maps show the disturbed HI morphology that NGC 5253 possesses, including tails, plumes and detached HI clouds. The high-resolution map reveals an HI plume at the SE and an HI structure at the NW that surrounds an Ha shell. We confirm that the kinematics of the neutral gas are highly perturbed and do not follow a rotation pattern. We discuss the outflow and infall scenarios to explain such disturbed kinematics, analyze the environment in which it resides, and compare it properties with those observed in similar star-forming dwarf galaxies. The radio-continuum emission of NGC 5253 is resolved and associated with the intense star-forming region at the center of the galaxy. We complete the analysis using multiwavelength data extracted from the literature. We estimate the SFR using this multiwavelength approach. NGC 5253 does not satisfy the Schmidt-Kennicutt law of star-formation, has a very low HI mass-to-light ratio when comparing with its stellar mass, and seems to be slightly metal-deficient in comparison with starbursts of similar baryonic mass. Taking into account all available multiwavelength data, we conclude that NGC 5253 is probably experiencing the infall of a diffuse, low-metallicity HI cloud along the minor axis of the galaxy, which is comprising the ISM and triggering the powerful starburst. The tidally disturbed material observed at the east and north of the galaxy is a consequence of this interaction, which probably started more than 100 Myr ago. The origin of this HI cloud may be related with a strong interaction between NGC 5253 and the late-type spiral galaxy M 83 in the past.Comment: 19 pages, 12 figures, accepted for publication in MNRA

Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feeding.

To understand hindbrain pathways involved in the control of food intake, we examined roles for calcitonin receptor (CALCR)-containing neurons in the NTS. Ablation of NTS Calcr abrogated the long-term suppression of food intake, but not aversive responses, by CALCR agonists. Similarly, activating CalcrNTS neurons decreased food intake and body weight but (unlike neighboring CckNTS cells) failed to promote aversion, revealing that CalcrNTS neurons mediate a non-aversive suppression of food intake. While both CalcrNTS and CckNTS neurons decreased feeding via projections to the PBN, CckNTS cells activated aversive CGRPPBN cells while CalcrNTS cells activated distinct non-CGRP PBN cells. Hence, CalcrNTS cells suppress feeding via non-aversive, non-CGRP PBN targets. Additionally, silencing CalcrNTS cells blunted food intake suppression by gut peptides and nutrients, increasing food intake and promoting obesity. Hence, CalcrNTS neurons define a hindbrain system that participates in physiological energy balance and suppresses food intake without activating aversive systems

Development of SimCells as a novel chassis for functional biosensors

This work serves as a proof-of-concept for bacterially derived SimCells (Simple Cells), which contain the cell machinery from bacteria and designed DNA (or potentially a simplified genome) to instruct the cell to carry out novel, specific tasks. SimCells represent a reprogrammable chassis without a native chromosome, which can host designed DNA to perform defined functions. In this paper, the use of Escherichia coli MC1000 ∆minD minicells as a non-reproducing chassis for SimCells was explored, as demonstrated by their ability to act as sensitive biosensors for small molecules. Highly purified minicells derived from E. coli strains containing gene circuits for biosensing were able to transduce the input signals from several small molecules (glucarate, acrylate and arabinose) into the production of green fluorescent protein (GFP). A mathematical model was developed to fit the experimental data for induction of gene expression in SimCells. The intracellular ATP level was shown to be important for SimCell function. A purification and storage protocol was developed to prepare SimCells which could retain their functions for an extended period of time. This study demonstrates that SimCells are able to perform as 'smart bioparticles' controlled by designed gene circuits

The 33S(n,α)30Si cross section measurement at n-TOF-EAR2 (CERN) : From 0.01 eV to the resonance region

The 33S(n,α)30Si cross section measurement, using 10B(n,α) as reference, at the n-TOF Experimental Area 2 (EAR2) facility at CERN is presented. Data from 0.01 eV to 100 keV are provided and, for the first time, the cross section is measured in the range from 0.01 eV to 10 keV. These data may be used for a future evaluation of the cross section because present evaluations exhibit large discrepancies. The 33S(n,α)30Si reaction is of interest in medical physics because of its possible use as a cooperative target to boron in Neutron Capture Therapy (NCT)

Measurement of 73 Ge(n,γ) cross sections and implications for stellar nucleosynthesis

© 2019 The Author(s). Published by Elsevier B.V.73 Ge(n,γ) cross sections were measured at the neutron time-of-flight facility n_TOF at CERN up to neutron energies of 300 keV, providing for the first time experimental data above 8 keV. Results indicate that the stellar cross section at kT=30 keV is 1.5 to 1.7 times higher than most theoretical predictions. The new cross sections result in a substantial decrease of 73 Ge produced in stars, which would explain the low isotopic abundance of 73 Ge in the solar system.Peer reviewe

Characterization of the n-TOF EAR-2 neutron beam

The experimental area 2 (EAR-2) at CERNs neutron time-of-flight facility (n-TOF), which is operational since 2014, is designed and built as a short-distance complement to the experimental area 1 (EAR-1). The Parallel Plate Avalanche Counter (PPAC) monitor experiment was performed to characterize the beam prole and the shape of the neutron 'ux at EAR-2. The prompt γ-flash which is used for calibrating the time-of-flight at EAR-1 is not seen by PPAC at EAR-2, shedding light on the physical origin of this γ-flash