112 research outputs found

    The Deconstruction of the Screens Limits and Frames in Moving Image Installations

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    UIDB/05021/2020 UIDP/05021/2020n the view of the continuous transformations in the structures of production, distribution and consumption of images, concepts such as expanded cinema or cinema of exhibition enlarged the spectrum of cinema to the contemporary art, which has also become a space to meditate about the fate of the cinematographic device. From a trans-historical and interdisciplinary approach – going from the pictorial perspectiva artificiallis to the pre-cinematographic instruments, cinema, and contemporary art – this paper seeks to reflect, by using the historical metaphor of the window, on the volatility and multiplicity of contemporary screens and their influence on today’s modes of vision. The paper also addresses the changes undergone in the image’s frames and the consequent paradigm shift in how the viewer physically relates with these images, summoning the work of the Portuguese artist Alexandre Estrela to consider the perceptive, cognitive and topological reconfigurations in the moving-image exhibition formats in museums and art galleries.publishersversionpublishe

    Da Reprodução à Apresentação

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    UIDB/05021/2020 UIDP/05021/2020Partindo de uma abordagem ao fantasmático enquanto elemento de experiência e percepção na arte contemporânea, este artigo procura reflectir acerca de determinadas dimensões técnicas, ópticas e performativas da projecção e da lanterna mágica presentes no trabalho dos artistas portugueses Renato Ferrão (Braga, 1975) e Francisco Tropa (Lisboa, 1968), que na sua obra recriam frequentemente dispositivos a partir dos princípios das lanternas mágicas, reflectindo acerca de diferentes motivos fantasmagóricos e virtuais inteligíveis nas instalações de arte. Através de um devir fantasmagórico e onírico, as obras Em Trabalho (2016-2017) de Renato Ferrão e Scenario (2011) de Francisco Tropa radicam num pensamento sobre a imagem na contemporaneidade técnica e, mais amplamente, acerca de elementos como a projecção, a obsolescência, a aura, a reprodução da imagem, a topologia da instalação, a materialidade e a imaterialidade, a representação e a apresentação.publishersversionpublishe

    A potência da origem e do incloncluso nas obras de Filipa César e Ângela Ferreira

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    UIDB/05021/2020 UIDP/05021/2020Numa problematização acerca das relações entre imagens em movimento, pós-colonialismo e arqui-vo, este texto aborda o filme Spell Reel (2017) de Filipa César (Porto, 1975) e a escultura-maquete ForMozambique (Model n.º 1 for Screen-Tribune-Kiosk Celebrating a Post-Independence Utopia) (2009) de Ângela Ferreira (Maputo, 1958) — obras que concretizam uma revisitação, interpretação e interrogação acerca das estruturas arquivísticas para interpelarem o início do cinema nos territórios pós-revolucionários africanos, solicitando pontos cegos do passado e disfunções do presente.As duas obras inscrevem o arquivo enquanto abertura para o futuro e atua-lização do originário: uma origem que não se determina apenas no que há no começo de algo, mas na procura daquilo que lhe é lacunar e fragmentário, existindo em potência e num estado inconcluso. Questioning the relationships between moving images, post-colonialism and archives, this text addresses the film Spell Reel(2017) by Filipa César (Porto, 1975) and the sculpture-maquette For Mozambique (Model n.º 1 for Screen-Tribune — Kiosk Celebrating a Post-Independence Utopia)(2009) by Ângela Ferreira (Maputo, 1958) — works that revisit, interpret and interrogate archival structures to approach the beginning of cinema in post-revolu-tionary African territories. By requesting blind spots from the past and dysfunctions of the present, both works inscribe the archive as an opening to the future and an updating of the original: an origin that is not only determined by what is at the beginning of something, but in the search for what is lacunal, fragmentary and in an unfinished state.publishersversionpublishe

    Fungal Gastroduodenitis

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    Candida infection of the gastrointestinal (GI) tract is rare in the immunocompetent individual. In immunocompromised patients, it frequently involves the oesophagus, but extra-oesophageal involvement is uncommon. We report a case of primary and isolated gastroduodenal candidiasis. Upper GI endoscopy with biopsy of gastric mucosa was crucial for making the diagnosis. The patient showed transient improvement after therapy with fluconazole

    Sarcoidose

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    Sarcoidosis is an inflammatory multisystemic disease of unknown etiology, which is characterized by the formation of noncaseating granulomas in the organs involved, mainly lungs and intrathoracic lymph nodes. Skin involvement occurs in 25-35%; it is usually an early finding and it is an accessible and safe location for histopathological study. Cutaneous lesions may present with a variety of morphologies, including papules, nodules, plaques, and infiltrated scars. The diagnosis of sarcoidosis is supported by the recognition of compatible clinical, imagiological and histopathologic features, and the exclusion of other granulomatous disorders. Early diagnosis and systemic treatment could prevent future complications.A sarcoidose consiste numa doença inflamatória multissistémica, de etiologia desconhecida, que se caracteriza pela formação de granulomas não-caseosos nos órgãos envolvidos, predominantemente pulmões e gânglios intratorácicos. O envolvimento cutâneo ocorre em cerca de 25-35% dos casos, é habitualmente um achado precoce e constitui um local acessível e seguro para estudo histológico. As lesões cutâneas podem ter várias apresentações, incluindo pápulas, nódulos, placas e cicatrizes infiltradas. O diagnóstico baseia-se no reconhecimento das características clínicas, imagiológicas e histológicas e exclusão de outras doenças granulomatosas. O diagnóstico precoce e tratamento sistémico (quando necessário) poderão prevenir complicações futuras

    Hiperplasia congénita da supra-renal não clássica (hcsr-nc) por deficiência de 21-hidroxilase: avaliação clínica e aconselhamento genético de duas famílias portuguesas

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    Introdução: A hiperplasia congénita da supra renal surge por deficiência de 21-hidroxilase em 90-95% dos casos. É uma das doenças hereditárias de transmissão autossómica recessiva mais frequente. A gravidade da doença resulta do grau de deficiência enzimática da 21-hidroxilase, que depende da mutação que ocorre no gene CYP21A2. Pode ter duas apresentações clínicas: a forma clássica (perdedora de sal ou simplesmente virilizante) mais grave e a forma não clássica (ou expressão tardia) com bloqueio enzimático menos grave. Objetivos: Estudo de duas famílias portuguesas com HCSR-NC para melhor avaliação clínica e aconselhamento genético dessas famílias.N/

    Public policies on healthcare-associated infections: a Brazil and UK case study

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    To summarize the historical events and drivers underlying public policy for the prevention and control of healthcare-associated infections in Brazil and in the United Kingdom. In doing so, the article aims to identify lessons and recommendations for future development of public policy. The analysis is based on a historical overview of national healthcare-associated infections programs taken from previously published sources. Findings highlight how the development of healthcare-associated infections prevention and control policies followed similar trajectories in Brazil and the United Kingdom. This can be conceptualized around four sequential phases: Formation, Consolidation, Standardization, and Monitoring and Evaluation. However, while we identified similar phases of development in Brazil and the United Kingdom, it can be seen that the former entered each stage around 20 years after the latter

    Screening for colorectal cancer leading into a new decade: the “Roaring ‘20s” for epigenetic biomarkers?

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    Colorectal cancer (CRC) has an important bearing (top five) on cancer incidence and mortality in the world. The etiology of sporadic CRC is related to the accumulation of genetic and epigenetic alterations that result in the appearance of cancer hallmarks such as abnormal proliferation, evasion of immune destruction, resistance to apoptosis, replicative immortality, and others, contributing to cancer promotion, invasion, and metastasis. It is estimated that, each year, at least four million people are diagnosed with CRC in the world. Depending on CRC staging at diagnosis, many of these patients die, as CRC is in the top four causes of cancer death in the world. New and improved screening tests for CRC are needed to detect the disease at an early stage and adopt patient management strategies to decrease the death toll. The three pillars of CRC screening are endoscopy, radiological imaging, and molecular assays. Endoscopic procedures comprise traditional colonoscopy, and more recently, capsule-based endoscopy. The main imaging modality remains Computed Tomography (CT) of the colon. Molecular approaches continue to grow in the diversity of biomarkers and the sophistication of the technologies deployed to detect them. What started with simple fecal occult blood tests has expanded to an armamentarium, including mutation detection and identification of aberrant epigenetic signatures known to be oncogenic. Biomarker-based screening methods have critical advantages and are likely to eclipse the classical modalities of imaging and endoscopy in the future. For example, imaging methods are costly and require highly specialized medical personnel. In the case of endoscopy, their invasiveness limits compliance from large swaths of the population, especially those with average CRC risk. Beyond mere discomfort and fear, there are legitimate iatrogenic concerns associated with endoscopy. The risks of perforation and infection make endoscopy best suited for a confirmatory role in cases where there are positive results from other diagnostic tests. Biomarker-based screening methods are largely non-invasive and are growing in scope. Epigenetic biomarkers, in particular, can be detected in feces and blood, are less invasive to the average-risk patient, detect early-stage CRC, and have a demonstrably superior patient follow-up. Given the heterogeneity of CRC as it evolves, optimal screening may require a battery of blood and stool tests, where each can leverage different pathways perturbed during carcinogenesis. What follows is a comprehensive, systematic review of the literature pertaining to the screening and diagnostic protocols used in CRC. Relevant articles were retrieved from the PubMed database using keywords including: “Screening”, “Diagnosis”, and “Biomarkers for CRC”. American and European clinical trials in progress were included as well.info:eu-repo/semantics/publishedVersio
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