Skewness as a probe of non-Gaussian initial conditions

We compute the skewness of the matter distribution arising from non-linear evolution and from non-Gaussian initial perturbations. We apply our result to a very generic class of models with non-Gaussian initial conditions and we estimate analytically the ratio between the skewness due to non-linear clustering and the part due to the intrinsic non-Gaussianity of the models. We finally extend our estimates to higher moments.Comment: 5 pages, 2 ps-figs., accepted for publication in PRD, rapid com

A Proposal of the European Association for the Study of Obesity to Improve the ICD-11 Diagnostic Criteria for Obesity Based on the Three Dimensions Etiology, Degree of Adiposity and Health Risk

Diagnostic criteria for complex medical conditions caused by a multitude of both genetic and environmental factors should be descriptive and avoid any attribution of causality. Furthermore, the wording used to describe a disorder should be evidence-based and avoid stigmatization of the affected individuals. Both terminology and categorizations should be readily comprehensible for healthcare professionals and guide clinical decision making. Uncertainties with respect to diagnostic issues and their implications may be addressed to direct future clinical research. In this context, the European Association of the Study of Obesity (EASO) considers it an important endeavor to review the current ICD-11 Beta Draft for the definition of overweight and obesity and to propose a substantial revision. We aim to provide an overview of the key issues that we deem relevant for the discussion of the diagnostic criteria. We first discuss the current ICD-10 criteria and those proposed in the ICD 11 Beta Draft. We conclude with our own proposal for diagnostic criteria, which we believe will improve the assessment of patients with obesity in a clinically meaningful way

Exploring Cosmic Origins with CORE: Survey requirements and mission design

Future observations of cosmic microwave background (CMB) polarisation havethe potential to answer some of the most fundamental questions of modernphysics and cosmology. In this paper, we list the requirements for a future CMBpolarisation survey addressing these scientific objectives, and discuss thedesign drivers of the CORE space mission proposed to ESA in answer to the "M5"call for a medium-sized mission. The rationale and options, and themethodologies used to assess the mission's performance, are of interest toother future CMB mission design studies. CORE is designed as a near-ultimateCMB polarisation mission which, for optimal complementarity with ground-basedobservations, will perform the observations that are known to be essential toCMB polarisation scienceand cannot be obtained by any other means than adedicated space mission

Knotty inflation and the dimensionality of spacetime

We suggest a structure for the vacuum comprised of a network of tightly knotted/linked flux tubes formed in a QCD-like cosmological phase transition and show that such a network can drive cosmological inflation. As the network can be topologically stable only in three space dimensions, this scenario provides a dynamical explanation for the existence of exactly three large spatial dimensions in our Universe

Exploring cosmic origins with CORE: Survey requirements and mission design

Future observations of cosmic microwave background (CMB) polarisation have the potential to answer some of the most fundamental questions of modern physics and cosmology. In this paper, we list the requirements for a future CMB polarisation survey addressing these scientific objectives, and discuss the design drivers of the CORE space mission proposed to ESA in answer to the "M5" call for a medium-sized mission. The rationale and options, and the methodologies used to assess the mission's performance, are of interest to other future CMB mission design studies. CORE is designed as a near-ultimate CMB polarisation mission which, for optimal complementarity with ground-based observations, will perform the observations that are known to be essential to CMB polarisation scienceand cannot be obtained by any other means than a dedicated space mission.Comment: 79 pages, 14 figure

Scalable fabrication of individual SWNT chem-FETs for gas sensing

We present a scalable, Deep-UV (220 nm) photolithography based process for fabricating low-power gas sensors integrating an individual single-walled carbon nanotube (SWNT) as a sensing element. SWNTs grow from defined catalyst (ferritin) islands, and their density is controlled by controlling the catalyst particle density. By designing the electrode dimensions based on the length distribution of SWNTs, a single-SWNT bridging yield of 30% has been achieved. Furthermore, we show that exposure to NO2 at room temperature results in a positive shift of the threshold voltage. A threshold shift of approximately 2 V for 500 ppb of NO2 is observed. The presented process also enables the possibility of fabricating carbon nanotube sensor arrays, as a large number of single-tube devices can be fabricated in each process run

Electrical initialization to erase history in hysteretic carbon nanotube transistors for sensing applications

Typically, carbon nanotube field effect transistors (CNFETs) based sensors exhibit substantial gate hysteresis and therefore, prior to measurements, require electrical initialization to erase electrical history of their threshold voltage (Vth(t)). Particularly, for CNFET gas sensors, which respond with small Vth shifts to analyte concentration changes, electrical initialization is necessary for reliable sensor operation. Here, we propose and demonstrate electrical initialization of CNFETs for sensing applications by applying triangular ambipolar pulse (TAP) sequences to the gate electrode