2,039 research outputs found
Embedding the concept of ecosystems services:The utilisation of ecological knowledge in different policy venues
The concept of ecosystem services is increasingly being promoted by academics and policy makers as a means to protect ecological systems through more informed decision making. A basic premise of this approach is that strengthening the ecological knowledge base will significantly enhance ecosystem health through more sensitive decision making. However, the existing literature on knowledge utilisation, and many previous attempts to improve decision making through better knowledge integration, suggest that producing âmore knowledgeâ is only ever a necessary but insufficient condition for greater policy success. We begin this paper by reviewing what is already known about the relationship between ecological knowledge development and utilisation, before introducing a set of theme issue papers that examineâfor the very first timeâhow this politically and scientifically salient relationship plays out across a number of vital policy venues such as land-use planning, policy-level impact assessment, and costâbenefit analysis. Following a detailed synthesis of the key findings of all the papers, this paper identifies and explores new research and policy challenges in this important and dynamic area of environmental governance
On the Classification of UGC1382 as a Giant Low Surface Brightness Galaxy
We provide evidence that UGC1382, long believed to be a passive elliptical
galaxy, is actually a giant low surface brightness (GLSB) galaxy which rivals
the archetypical GLSB Malin 1 in size. Like other GLSB galaxies, it has two
components: a high surface brightness disk galaxy surrounded by an extended low
surface brightness (LSB) disk. For UGC1382, the central component is a
lenticular system with an effective radius of 6 kpc. Beyond this, the LSB disk
has an effective radius of ~38 kpc and an extrapolated central surface
brightness of ~26 mag/arcsec^2. Both components have a combined stellar mass of
~8x10^10 M_sun, and are embedded in a massive (10^10 M_sun) low-density (<3
M_sun/pc^2) HI disk with a radius of 110 kpc, making this one of the largest
isolated disk galaxies known. The system resides in a massive dark matter halo
of at least 2x10^12 M_sun. Although possibly part of a small group, its low
density environment likely plays a role in the formation and retention of the
giant LSB and HI disks. We model the spectral energy distributions and find
that the LSB disk is likely older than the lenticular component. UGC1382 has
UV-optical colors typical of galaxies transitioning through the green valley.
Within the LSB disk are spiral arms forming stars at extremely low
efficiencies. The gas depletion time scale of ~10^11 yr suggests that UGC1382
may be a very long term resident of the green valley. We find that the
formation and evolution of the LSB disk is best explained by the accretion of
gas-rich LSB dwarf galaxies.Comment: 17 pages, 16 figures, 4 tables; accepted to the Astrophysical Journa
Base extrusion is found at helical junctions between right- and left-handed forms of DNA and RNA
Base extrusion is a major structural feature at the junction between B- and Z-DNA (the BâZ junction) where a base pair is broken, and the two bases are extruded from the double helix. Despite the demonstration of base extrusion at the BâZ junction, it is not clear whether a similar base extrusion occurs at other types of junctions involving the left-handed Z conformation. Here, we investigate structural changes of bases at three Z-form junctions: DNA BâZ and ZâZ and RNA AâZ junctions. By monitoring fluorescently labeled duplex nucleic acids using 2-aminopurines at various positions relative to the junction point, we show that base extrusion occurs not only at the DNA BâZ junction, but also at the RNA AâZ and DNA ZâZ junctions. Our data suggest that base extrusion is a general feature of Z-form nucleic-acid junctions.Korean Science and Engineering Foundation (grant NRL-2006-02287)Korea (South). Ministry of Science and Technology (21C Frontier Functional Proteomics Program FPR08B2-270)Korean Science and Engineering Foundation (Ubiquitome Research Program M105 33010001-05N3301-00100)Korea Research Foundation (MOEHRD, Basic Research Promotion Fund; KRF-2005-070-C00078
Foot-and-Mouth Disease Impact on Smallholders - What Do We Know, What Don't We Know and How Can We Find Out More?
Foot-and-mouth disease (FMD) endemic regions contain three-quarters of the world's FMD susceptible livestock and most of the world's poor livestock keepers. Yet FMD impact on smallholders in these regions is poorly understood. Diseases of low mortality can exert a large impact if incidence is high. Modelling and field studies commonly find high FMD incidence in endemic countries. Sero-surveys typically find a third of young cattle are sero-positive, however, the proportion of sero-positive animals that developed disease, and resulting impact, are unknown. The few smallholder FMD impact studies that have been performed assessed different aspects of impact, using different approaches. They find that FMD impact can be high (>10% of annual household income). However, impact is highly variable, being a function of FMD incidence and dependency on activities affected by FMD. FMD restricts investment in productive but less FMD-resilient farming methods, however, other barriers to efficient production may exist, reducing the benefits of FMD control. Applying control measures is costly and can have wide-reaching negative impacts; veterinary-cordon-fences may damage wildlife populations, and livestock movement restrictions and trade bans damage farmer profits and the wider economy. When control measures are ineffective, farmers, society and wildlife may experience the burden of control without reducing disease burden. Foot-and-mouth disease control has benefitted smallholders in South America and elsewhere. Success takes decades of regional cooperation with effective veterinary services and widespread farmer participation. However, both the likelihood of success and the full cost of control measures must be considered. Controlling FMD in smallholder systems is challenging, particularly when movement restrictions are hard to enforce. In parts of Africa this is compounded by endemically infected wildlife and limited vaccine performance. This paper reviews FMD impact on smallholders in endemic countries. Significant evidence gaps exist and guidance on the design of FMD impact studies is provided
Towards a World Environment Organisation?
Summary This article explores the possible need for a new international body to address environmental problems along the lines of a World Environment Organisation (WEO). A case is made that existing institutions and policy mechanisms for combating environmental problems have fallen short in several crucial respects. Perhaps most notable among the failings of contemporary approaches is a failure of internalisation. A WEO is argued to facilitate the internationalisation of environmental costs, as well as redress many of the other problems identified with existing international cooperative responses. The article is a summary of a larger project on the perspectives of different LDCs towards the possible creation of such an institution
How are professional programs from diverse disciplines approaching the development and assessment of competence at a mid-sized Canadian university?
Time-honoured university policies, such as the credit-hour and academic freedom, present challenges for professional education programs tasked with operationalizing entry-to-practice competence frameworks for professional accreditation. A single embedded case study was used to explore how professional programs from one mid-sized Canadian university are approaching and perhaps problematizing the development and assessment of competence. Semi-structured interviews were conducted with educational leaders (faculty and staff, n=21) from a sample of nine programs. Following a grounded theory approach to qualitative analysis, the constant comparative method was used to inductively discern similarities and differences across programs, and to begin building theory about approaches to operationalization. While limited in scope given the use of a single university, our findings highlight: (a) diversity in approaches to operationalization across programs, (b) common attributes which can be used to classify the manner in which these programs operationalize competence, and (c) challenges with supporting faculty to buy in to competency-informed pedagogy and assessment. Given these findings, it is recommended that professional accrediting bodies and education programs spend time to consider the role university-based programs play in determining competence for entry-to-practice, as well their intents for implementing a competence framework, to ensure sufficiency in the approaches being used
A Novel Mechanism of TRAF Signaling Revealed by Structural and Functional Analyses of the TRADDâTRAF2 Interaction
AbstractTRAF proteins are major mediators for the cell activation, cell survival, and antiapoptotic functions of the TNF receptor superfamily. They can be recruited to activated TNF receptors either by direct interactions with the receptors or indirectly via the adaptor protein TRADD. We now report the structure of the TRADD-TRAF2 complex, which is highly distinct from receptorâTRAF2 interactions. This interaction is significantly stronger and we show by an in vivo signaling assay that TRAF2 signaling is more readily initiated by TRADD than by direct receptorâTRAF2 interactions. TRADD is specific for TRAF1 and TRAF2, which ensures the recruitment of cIAPs for the direct inhibition of caspase activation in the signaling complex. The stronger affinity and unique specificity of the TRADDâTRAF2 interaction are crucial for the suppression of apoptosis and provide a mechanistic basis for the perturbation of TRAF recruitment in sensitizing cell death induction
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