31 research outputs found
Functional Relation of interquark potential with interquark distance
The functional relation between interquark potential and interquark distance
is explicitly derived by considering the Nambu--Goto action in the background. It is also shown that a similar relation holds in a
general background. The implications of this relation for confinement are
briefly discussed.Comment: 11pages, 2 figures, reference adde
Hidden functional relation in Large-N Quark-Monopole system at finite temperature
The quark-monopole potential is computed at finite temperature in the context
of correspondence. It is found that the potential is invariant under
and . As in the quark-quark case there exists a
maximum separation between quark and monopole, and -dependence of the
potential exhibits a bifurcation behavior. We find a functional relation
which is responsible for the bifurcation.
The remarkable property of this relation is that it makes a relation between
physical quantities defined at the boundary through a quantity defined at
the bulk. The physical implication of this relation for the existence of the
extra dimension is speculated.Comment: 22 pages, 3 figures, v1 one more reference added v2 version to appear
in NP
Hydrodynamics of domain growth in nematic liquid crystals
We study the growth of aligned domains in nematic liquid crystals. Results
are obtained solving the Beris-Edwards equations of motion using the lattice
Boltzmann approach. Spatial anisotropy in the domain growth is shown to be a
consequence of the flow induced by the changing order parameter field
(backflow). The generalization of the results to the growth of a cylindrical
domain, which involves the dynamics of a defect ring, is discussed.Comment: 12 revtex-style pages, including 12 figures; small changes before
publicatio
External validation of multidimensional prognostic indices (ADO, BODEx and DOSE) in a primary care international cohort (PROEPOC/COPD cohort)
Background: Due to the heterogeneous and systemic nature of the chronic obstructive pulmonary disease (COPD), the new guidelines are oriented toward individualized attention. Multidimensional scales could facilitate its proper clinical and prognostic assessment, but not all of them were validated in an international primary care cohort, different from the original ones used for model development. Therefore, our main aim is to assess the prognostic capacity of the ADO, BODEx and DOSE indices in primary care for predicting mortality in COPD patients and to validate the models obtained in subgroups of patients, classified by revised Global Initiative for Chronic Obstructive Lung Disease (2011) and updated Spanish Guideline (2014). Besides, we want to confirm that the prognostic capacity of all indices increases if the number of exacerbations is substituted by the interval between them and to assess the impact on health of the patient''s lifestyle, social network and adherence to treatment. Methods: Design: External validation of scales, open and prospective cohort study in primary care. Setting: 36 health centres in 6 European high, medium and low income countries. Subjects: 477 patients diagnosed with COPD, captured in clinical visit by their General Practitioner/Nurse. Predictors: Detailed patient history, exacerbations, lung function test and questionnaires at baseline. Outcomes: Exacerbations, all-cause mortality and specific mortality, within 5 years of recruitment. Analysis: Multivariate logistic regression and Cox regression will be used. Possible non-linear effect of the indices will be studied by using Structured Additive Regression models with penalised splines. Subsequently, we will assess different aspects of the regression models: discrimination, calibration and diagnostic precision. Clinical variables modulated in primary care and the interval between exacerbations will be considered and incorporated into the analysis. Discussion: The Research Agenda for General Practice/Family Medicine highlights that the evidence on predictive values of prognostic indices in primary care is scarce. A prospective cohort like that of PROEPOC/COPD provides good opportunities for research into COPD and make communication easier between family practitioners, nursing staff, pneumologists and other professionals, supporting a multi-disciplinary approach to the treatment of these patients. Trial registration:ISRCTN52402811. Date: 15/01/2015. Prospectively registered
Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020
We show the distribution of SARS-CoV-2 genetic clades over time and between countries and outline potential genomic surveillance objectives. We applied three available genomic nomenclature systems for SARS-CoV-2 to all sequence data from the WHO European Region available during the COVID-19 pandemic until 10 July 2020. We highlight the importance of real-time sequencing and data dissemination in a pandemic situation. We provide a comparison of the nomenclatures and lay a foundation for future European genomic surveillance of SARS-CoV-2.Peer reviewe