Interaction effects of fermentation time and sourdough content on the size and acidity in bread

The use of sourdough to provide certain physical, organoleptic and nutritional properties to bread is one of the most used biotechnological processes in the production of cereal-based foods. Sourdough, yeast and fermentation time are elements that provide rising to the bread, in addition to aroma, flavour and nutritional properties. The time of fermentation of the dough before baking and the portion of sourdough added in the dough pieces are decisive on the acids formation by microbiological action, and thus, the properties of the bread. The physical aspect is also an important factor in the final product, and it can be widely affected according to the percentage of sourdough used and the fermentation time prior to baking. This is due to the variation in the rheological properties of the dough and possibly to the competition existing in the microbiota development. In this work, the interaction effects of fermentation time and sourdough content on the size and acidity in bread are assessed. For this purpose, bread samples were prepared with a fixed amount of yeast and 0, 20 and 50% sourdough portions. Afterwards, they were allowed to ferment periods of 0, 60, 120, 180, 240, 300 and 360 minutes before being baked. The results obtained are reported in the present work.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Human occupations of Northern Morocco, Middle and Upper Palaeolithic. New data on the basis of archaeological research projects from 2005 to 2020

Nous présentons dans ce travail, un panorama synthétique des occupations humaines du Nord du Maroc, en mettant l’accent sur l’association des données anthropologiques et des données culturelles, ceci dans un cadre chronologique compris entre le Paléolithique Moyen (MSA) et le Paléolithique Supérieur. Nous présentons aussi les projets développés, durant ces 15 dernières années, et les résultats les plus intéressants que nous avons obtenus. Pour conclure, nous proposons quelques réflexions sur l’évaluation culturelle et historique des enregistrements archéologiques de la région de Tétouan dans les périodes du Paléolithique Moyen et Supérieur.In this work, we present a synthetic panorama of the human occupations of northern Morocco, with an emphasis on the association of anthropological with cultural records, within the framework of the Middle Palaeolithic (MSA) and the Upper Palaeolithic. We also present the projects developed over the past 15 years and the most interesting results we have obtained. And we conclude bay providing some reflections on the cultural and historical evaluation of the archaeological records from the Tetouan region in the Middle and the Upper Palaeolithic phases.Les résultats et les conclusions de cet article ont été obtenus grâce aux études qui ont été réalisées dans le cadre de la coopération scientifique internationale qui a permis le développement des projets de recherches archéologiques durant les quinze dernières années et qu’on peut résumer comme suit : • Les matières premières dans la préhistoire du détroit de Gibraltar. Code A/2893/05. Entités participantes : Université de Cadix (Espagne) et Université Abdelmalek Essaâdi (Maroc). Durée, de janvier 2006 à décembre 2006. Chercheurs responsables : Salvador Domínguez-Bella et Ali Maate. • Etude des collections du Musée Archéologique de Tétouan (I). Début de l’inventaire général et de l’analyse de certaines collections thématiques. Code : A/6867/06. Entités participantes : Université de Cadix (Espagne), Institut National des Sciences de l’Archéologie et du Patrimoine (Rabat) et Université Abdelmalek Esaâdi (Tanger-Tétouan) (Maroc). Durée, de janvier 2007 à décembre 2007. Chercheurs responsables : Mehdi Zouak et José Ramos-Muñoz. • Les matières premières dans la Préhistoire du détroit de Gibraltar. Code A/6317/06. Entités participantes : Université de Cadix (Espagne) et Université Abdelmalek Essaâdi (Maroc). Durée, de janvier 2007 à décembre 2007. Chercheurs responsables : Salvador Domínguez-Bella et Ali Maate. • Contribution à l’élaboration de la Carte archéologique du Nord du Maroc (Région Tanger-Tétouan). Analyse de faisabilité et conception du projet. Code A/5790/06. Entités participantes : Université de Cadix (Espagne) et Université Abdelmalek Esaâdi (Tanger-Tétouan, Maroc). Durée, de janvier 2007 à décembre 2007. Chercheurs responsables : Darío Bernal et Baraka Raissounni. • Étude des collections du Musée Archéologique de Tétouan (II). Début de l’inventaire général et de l’analyse de certaines collections thématiques. Code A/010823/07. Entités participantes : Université de Cadix (Espagne), Institut National des Sciences de l’Archéologie et du Patrimoine (Rabat) et Université Abdelmalek Essaâdi (Maroc). Durée, de janvier 2008 à décembre 2008. Chercheurs responsables : José Ramos-Muñoz. et Mehdi Zouak. • Proposition pour le remodelage du contenu du Musée Archéologique de Tétouan. Code AP/040139/11. Entités participantes : Université Abdelmalek Esaâdi (Tanger-Tétouan) (Maroc) et Université de Cadix (Espagne). Durée, de janvier 2012 à décembre 2012. Chercheurs responsables : José Ramos-Muñoz. et Ali Maate. • Projet Carte Archéologique du Nord du Maroc. Région de Tanger-Tétouan. Codes : DRCTT/08/328 ; DRCTT/09/267 ; DRCTT/ ; DRCTT/09/279 ; DRCTT/10/314, DRCTT/11/106, IRMHS-TT/12-48, IRMHS-TT/459/12, 0-094-2011 (BOE 314, 30-12-2011). Organismes de financement : AECID, Junta de Andalucía (Groupe PAI-HUM-440), Université de Cadix (Espagne). Entités participantes : Institut Nacional des Sciences de l’Archéologie et du Patrimoine (Rabat), Université Abdelmalek Esaâdi (Tanger-Tétouan) (Maroc) et Université de Cadix (Espagne). Durée, de janvier 2008 à décembre 2012. Chercheurs responsables : Mehdi Zouak, Abdelaziz El Khayari, Baraka Raissouni, Darío Bernal-Casasola et José Ramos-Muñoz. • Convention de collaboration pour la création du Laboratoire d’Archéologie et du Patrimoine Meknassi de la Région Tanger-Tétouan et le développement de la recherche archéologique et patrimoniale. Entités participantes : Université Abdelmalek Essaâdi, Université de Cadix et Direction Régionale de la Culture de la Région Tanger-Tétouan. Durée : du 24 mai 2012 au 24 mai 2017. Chercheurs responsables : Mehdi Zouak, Darío Bernal, José Ramos-Muñoz., Baraka Raissouni, Mostapha Ghottes et Tarek Moujoud. • Análisis de sociedades prehistóricas del Paleolítico Medio al Neolítico Final en las dos orillas del Estrecho de Gibraltar. Relaciones y contactos -HAR2017-8734P- (Ministerio de Economía, Industria y Competitividad -Agencia Estatal de Investigación, co financé par les fonds FEDER. Chercheurs responsables : José Ramos-Muñoz. et Salvador Domínguez-Bella. Nous tennons donc à remercier tous les chercheurs, les experts et les entités scientifiques, financières et administratives, qui ont permis la réalisation de ces projets de recherches archéologiques de 2005 à 2020

Role of age and comorbidities in mortality of patients with infective endocarditis

[Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. [Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. [Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. [Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group

Effectiveness of an intervention for improving drug prescription in primary care patients with multimorbidity and polypharmacy:Study protocol of a cluster randomized clinical trial (Multi-PAP project)

This study was funded by the Fondo de Investigaciones Sanitarias ISCIII (Grant Numbers PI15/00276, PI15/00572, PI15/00996), REDISSEC (Project Numbers RD12/0001/0012, RD16/0001/0005), and the European Regional Development Fund ("A way to build Europe").Background: Multimorbidity is associated with negative effects both on people's health and on healthcare systems. A key problem linked to multimorbidity is polypharmacy, which in turn is associated with increased risk of partly preventable adverse effects, including mortality. The Ariadne principles describe a model of care based on a thorough assessment of diseases, treatments (and potential interactions), clinical status, context and preferences of patients with multimorbidity, with the aim of prioritizing and sharing realistic treatment goals that guide an individualized management. The aim of this study is to evaluate the effectiveness of a complex intervention that implements the Ariadne principles in a population of young-old patients with multimorbidity and polypharmacy. The intervention seeks to improve the appropriateness of prescribing in primary care (PC), as measured by the medication appropriateness index (MAI) score at 6 and 12months, as compared with usual care. Methods/Design: Design:pragmatic cluster randomized clinical trial. Unit of randomization: family physician (FP). Unit of analysis: patient. Scope: PC health centres in three autonomous communities: Aragon, Madrid, and Andalusia (Spain). Population: patients aged 65-74years with multimorbidity (≥3 chronic diseases) and polypharmacy (≥5 drugs prescribed in ≥3months). Sample size: n=400 (200 per study arm). Intervention: complex intervention based on the implementation of the Ariadne principles with two components: (1) FP training and (2) FP-patient interview. Outcomes: MAI score, health services use, quality of life (Euroqol 5D-5L), pharmacotherapy and adherence to treatment (Morisky-Green, Haynes-Sackett), and clinical and socio-demographic variables. Statistical analysis: primary outcome is the difference in MAI score between T0 and T1 and corresponding 95% confidence interval. Adjustment for confounding factors will be performed by multilevel analysis. All analyses will be carried out in accordance with the intention-to-treat principle. Discussion: It is essential to provide evidence concerning interventions on PC patients with polypharmacy and multimorbidity, conducted in the context of routine clinical practice, and involving young-old patients with significant potential for preventing negative health outcomes. Trial registration: Clinicaltrials.gov, NCT02866799Publisher PDFPeer reviewe

Vocabulario de la sociedad civil, la ruralidad y los movimientos sociales en América Latina

El Vocabulario de la Sociedad Civil, la Ruralidad y los Movimientos Sociales en América Latina tiene como objetivo desarrollar vocablos relacionados con temas de gran trascendencia para la vida colectiva de la población Latinoamericana; pretende introducir a estudiantes, personas del ámbito académico y activistas en la comprensión de estas categorías de análisis. A través de la mirada de 70 especialistas que participaron en este vocabulario, es posible comprender muchos de los términos que se utilizan dentro de la investigación social y áreas relacionadas con las ciencias políticas, ambientales y rurales, a partir de una mayor explicación y detalle. Es por ello que se inserta este trabajo desde una mirada colectiva y amplia de los conceptos que se exponen. En este libro podrá encontrar las ideas de varios autores y autoras de distintas universidades, con una visión multi, inter y transdisciplinaria. El esfuerzo que se realizó para conjuntar varios términos y analizar su compleja red de interpretaciones, permitirá que este manuscrito pueda ser consultado por estudiantes, personas del ámbito científico-académico, y ciudadanía; porque contiene el estado del arte, la historia del paulatino avance de múltiples conceptos y su vigencia en el contexto actual

Actualidad y prospectiva de la investigación científica en el Centro Universitario Amecameca de la Universidad Autónoma del Estado de México

Con responsabilidad, se organizó un programa cuya finalidad fuera publicitar con transparencia dichos avances, a través de un esfuerzo de rendición de cuentas a la comunidad inmediata, la universitaria, y a la comunidad abierta, la sociedad que la principal referencia para tal efecto. El programa se concretiza a través del presente libro, conformado con una inspiración de investigación multidisciplinaria; sin embargo, para llegar a tal fin, el reto es realizar el proceso de búsqueda y generación de conocimiento transitando hacia la colaboración de los cuerpos académicos, que puedan construir nuevos conocimientos fortalecidos por la convergencia de diferentes campos del saber. En consecuencia, la primera etapa de esta estrategia es la publicidad de los trabajos investigativos ejercidos, para hacer un balance al día, pero también proyectar el futuro de cada campo y área del conocimiento. La organización explicativa está organizada por tres bloques representativos del quehacer en la generación de conocimiento del Centro Universitario, un primer bloque centra el interés en las humanidades, educación y sustentabilidad; el segundo bloque lo integra la reflexión científica sobre la construcción democrática, derechos humanos y equidad de género; en el tercer segmento se destina a la seguridad alimentaria, salud pública y sistemas agropecuarios. La actualidad de la investigación eleva la producción lograda y lo que en el momento se encuentra en construcción y los alcances que produce para la docencia, la investigación misma, y para la sociedad en general. La prospectiva es un área que todos los capítulos desarrollan con el propósito de delinear los alcances innovadores por andar en teoría, metodología e incluso en los saberes mismo

Avance de los resultados de la campaña de documentación arqueológica en la necrópolis megalítica de La Lentejuela (Teba-Málaga)

On the occasion of the prospecting and digital documentation campaign developed in the megalithic necropolis of La Lentejuela during July 2021, we present a preview of the results. The application of new archaeological record techniques such as 3D scanning or photogrammetry has made it possible to document with higher resolution a site with great potential for the knowledge of megalithism in the region.Con motivo de la campaña de prospección y documentación digital desarrollada en la necrópolis megalítica de La Lentejuela durante el mes de julio de 2021 presentamos un avance de los resultados. La aplicación de nuevas técnicas de registro arqueológico como el escáner 3D o la fotogrametría ha permitido documentar con mayor resolución un yacimiento con gran potencial para el conocimiento del megalitismo en la región

Mis casos Clínicos de Odontopediatría y Ortodoncia

Libro que conjunta casos en el área de Odontopediatría y OrtodonciaEs para los integrantes de la Red de Investigación en Estomatología (RIE) una enorme alegría presentar el tercer libro del 2021, sobre casos clínicos, revisiones de la literatura e investigaciones. La RIE está integrada por cuerpos académicos de la UAEH, UAEM, UAC y UdeG

Prosthetic Valve Candida spp. Endocarditis: New Insights Into Long-term Prognosis—The ESCAPE Study

International audienceBackground: Prosthetic valve endocarditis caused by Candida spp. (PVE-C) is rare and devastating, with international guidelines based on expert recommendations supporting the combination of surgery and subsequent azole treatment.Methods: We retrospectively analyzed PVE-C cases collected in Spain and France between 2001 and 2015, with a focus on management and outcome.Results: Forty-six cases were followed up for a median of 9 months. Twenty-two patients (48%) had a history of endocarditis, 30 cases (65%) were nosocomial or healthcare related, and 9 (20%) patients were intravenous drug users. "Induction" therapy consisted mainly of liposomal amphotericin B (L-amB)-based (n = 21) or echinocandin-based therapy (n = 13). Overall, 19 patients (41%) were operated on. Patients <66 years old and without cardiac failure were more likely to undergo cardiac surgery (adjusted odds ratios [aORs], 6.80 [95% confidence interval [CI], 1.59-29.13] and 10.92 [1.15-104.06], respectively). Surgery was not associated with better survival rates at 6 months. Patients who received L-amB alone had a better 6-month survival rate than those who received an echinocandin alone (aOR, 13.52; 95% CI, 1.03-838.10). "Maintenance" fluconazole therapy, prescribed in 21 patients for a median duration of 13 months (range, 2-84 months), led to minor adverse effects.Conclusion: L-amB induction treatment improves survival in patients with PVE-C. Medical treatment followed by long-term maintenance fluconazole may be the best treatment option for frail patients