Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020

We show the distribution of SARS-CoV-2 genetic clades over time and between countries and outline potential genomic surveillance objectives. We applied three available genomic nomenclature systems for SARS-CoV-2 to all sequence data from the WHO European Region available during the COVID-19 pandemic until 10 July 2020. We highlight the importance of real-time sequencing and data dissemination in a pandemic situation. We provide a comparison of the nomenclatures and lay a foundation for future European genomic surveillance of SARS-CoV-2.Peer reviewe

Bioavailability of sedimentary contaminants subject to deposit-feeder digestion

cited By 173International audienceContaminants in sediments are less available than their concentrations might imply, but measures of this availability have been generally lacking. Sediments ingested by benthic animals can be expected to undergo a unique chemical environment controlled by the digestive chemistry of the organism. We measured solubilization of sedimentary contaminants-Cu, Pb, and polycyclic aromatic hydrocarbons (PAH)-by digestive fluids extracted from marine invertebrates. Bioavailability of these contaminants, thus measured, is a small fraction of total contaminant loading-typically 1-10%. The amounts of metals solubilized by digestive fluids were orders of magnitude greater than would be predicted from water-solid partitioning with clean seawater, although they correlated well with solubilization by seawater. Digestive fluids from two different animal species solubilized different amounts of metals, indicating that bioavailability varies among species even under constant mode of uptake. High concentrations of solubilizing agents, such as amino acids for metals and surfactants for PAH, in the digestive fluids can explain the enhanced solubilization. This biomimetic approach to contaminant measurement provides the basis for more accurate mechanistic and routine assessments of environmental impact