11 research outputs found

    Paralelización a algoritmos de compresión fractal de imágenes

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    Se analiza la paralelización de un algoritmo clásico de compresión fractal de imagenes, utilizando procesadores heterogéneos conectados en red con un soporte de procesamiento distribuido basado en PVM y XPVM. En particular se discuten dos métricas de interés: el speed-up obtenible (separando los tiempos propios del overhead de comunicaciones) al incrementar el número de procesadores y la pérdida resultante del índice de compresión alcanzado. Si bien se trata de una clase de algoritmo muy particular, resulta de interés tecnológico sobre todo en aplicaciones donde la información es comprimida una vez y almacenada para su recuperación en consulta muchas veces (por ejemplo en servidores de información InterNet) ya que los índices de compresión alcanzables con una pérdida aceptable son muy altos y al mismo tiempo el algortimo de descompresión es muy rápido. Por último se discute el efecto de variar el particionamiento de la imagen sobre los tiempos de procesamiento y la posibilidad de realizar un particionamiento adaptivo con el fin de optimizar la relación índice de compresión/pérdida aceptable sin deterioro del speed-up.Eje: Procesamiento distribuido y paralelo. Tratamiento de señalesRed de Universidades con Carreras en Informática (RedUNCI

    Contaminanti nello zooplancton

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    Not availableContaminanti nello zooplancton nell\u27ambito del progetto di ricerca "Indagini su DDT e sostanze pericolose nell\u27ecosistema del Lago Maggiore"

    Contaminanti nello zooplancton

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    Not availableIndagini su DDT e sostanze pericolose nell\u27ecosistema del Lago Maggiore. Programma 2013-2015. Rapporto annuale 2013 - Contaminanti nello zooplancto

    Trophic Niches, Trophic Positions, and Niche Overlaps between Non-Native and Native Fish Species in a Subalpine Lake

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    In the last century, Italian freshwater ecosystems have been invaded by several non-native fish species. In the subalpine Lake Mergozzo (northern Italy), several recently introduced non-native species dramatically expanded their populations. We used carbon and nitrogen stable isotopes to describe the isotopic niches and trophic positions of native and non-native fish species in Lake Mergozzo. We evaluated their trophic niches, trophic diversity, trophic redundancy and trophic evenness utilizing isotopic niche metrics, and estimated asymmetrical niche overlaps. The trophic traits of non-native fish species and Perca fluviatilis clearly define them as trophic generalists, in terms of among-individual variability of their isotopic niches. The historical increase in abundance of fish non-native species in this lake, their dominance by numbers and biomass within the assemblage, and their broad asymmetrical niche overlaps suggest that their higher degree of trophic generalism might have been one of the key factors that have promoted the invasion of the recipient community

    From research to rapid response: mass COVID-19 testing by volunteers at the Centre for Genomic Regulation

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    The COVID-19 pandemic has posed and is continuously posing enormous societal and health challenges worldwide. The research community has mobilized to develop novel projects to find a cure or a vaccine, as well as to contribute to mass testing, which has been a critical measure to contain the infection in several countries. Through this article, we share our experiences and learnings as a group of volunteers at the Centre for Genomic Regulation (CRG) in Barcelona, Spain. As members of the ORFEU project, an initiative by the Government of Catalonia to achieve mass testing of people at risk and contain the epidemic in Spain, we share our motivations, challenges and the key lessons learnt, which we feel will help better prepare the global society to address similar situations in the future.The ORFEU program was created by the Catalan Enterprise and Knowledge Department with the Department of Health and funded by the Government of Catalonia, who trusted the expertise of research institutes to add value to the health system during the pandemic. We also extend our thanks to the Spanish Ministry of Science and Innovation to the EMBL partnership, the Centro de Excelencia Severo Ochoa, the CERCA Programme / Generalitat de Catalunya, the Spanish Ministry of Science and Innovation through the Instituto de Salud Carlos III, the Generalitat de Catalunya through Departament de Salut and Departament d’Empresa i Coneixement, and the co-financing by the Spanish Ministry of Economy, Industry and Competitiveness (MEIC) with funds from the European Regional Development Fund (ERDF) corresponding to the 2014-2020 Smart Growth Operating Program. We acknowledge support of the Spanish Ministry of Science and Innovation through the Instituto de Salud Carlos III, to the EMBL partnership and to the Co-financing with funds from the European Regional Development Fund corresponding to the Programa Operativo FEDER Plurirregional de España (POPE) 2014-2020. We acknowledge also support of the Centro de Excelencia Severo Ochoa and the Generalitat de Catalunya through the CERCA Programme, through Departament de Salut and Departament d’Empresa i Coneixement and the Co-financing with funds from the European Regional Development Fund by the Secretaria d’Universitats i Recerca corresponding to the Programa Operatiu FEDER de Catalunya 2014-202

    Plankton dynamics across the freshwater, transitional and marine research sites of the LTER-Italy Network. Patterns, fluctuations, drivers

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    A first synoptic and trans-domain overview of plankton dynamics was conducted across the aquatic sites belonging to the Italian Long-Term Ecological Research Network (LTER-Italy). Based on published studies, checked and complemented with unpublished information, we investigated phytoplankton and zooplankton annual dynamics and long-term changes across domains: from the large subalpine lakes to mountain lakes and artificial lakes, from lagoons to marine coastal ecosystems. This study permitted identifying common and unique environmental drivers and ecological functional processes controlling seasonal and long-term temporal course. The most relevant patterns of plankton seasonal succession were revealed, showing that the driving factors were nutrient availability, stratification regime, and freshwater inflow. Phytoplankton and mesozooplankton displayed a wide interannual variability at most sites. Unidirectional or linear long-term trends were rarely detected but all sites were impacted across the years by at least one, but in many case several major stressor(s): nutrient inputs, meteo-climatic variability at the local and regional scale, and direct human activities at specific sites. Different climatic and anthropic forcings frequently co-occurred, whereby the responses of plankton communities were the result of this environmental complexity. Overall, the LTER investigations are providing an unparalleled framework of knowledge to evaluate changes in the aquatic pelagic systems and management options

    Improved diagnosis of rare disease patients through systematic detection of runs of homozygosity

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    Autozygosity is associated with an increased risk of genetic rare disease, thus being a relevant factor for clinical genetic studies. More than 2400 exome sequencing data sets were analyzed and screened for autozygosity on the basis of detection of >1 Mbp runs of homozygosity (ROHs). A model was built to predict if an individual is likely to be a consanguineous offspring (accuracy, 98%), and probability of consanguinity ranges were established according to the total ROH size. Application of the model resulted in the reclassification of the consanguinity status of 12% of the patients. The analysis of a subset of 79 consanguineous cases with the Rare Disease (RD)-Connect Genome-Phenome Analysis Platform, combining variant filtering and homozygosity mapping, enabled a 50% reduction in the number of candidate variants and the identification of homozygous pathogenic variants in 41 patients, with an overall diagnostic yield of 52%. The newly defined consanguinity ranges provide, for the first time, specific ROH thresholds to estimate inbreeding within a pedigree on disparate exome sequencing data, enabling confirmation or (re)classification of consanguineous status, hence increasing the efficiency of molecular diagnosis and reporting on secondary consanguinity findings, as recommended by American College of Medical Genetics and Genomics guidelines.Supported by European Union projects RD-Connect, Solve-RD, and European Joint Programme of Rare Diseases (EJP-RD) grants FP7 305444, H2020 779257, and H2020 825575; Instituto de Salud Carlos III grants PT13/0001/0044 and PT17/0009/0019; Instituto Nacional de Bioinformática; ELIXIR Implementation Studies; European Union projects BBMRI-LPC EU FP7 313010, NeurOmics EU FP7 305121, and Undiagnosed Rare Disease Program of Catalonia (Departament de Salut, Generalitat de CatalunyaSLT002/16/00174); Canadian Institutes of Health Research Foundation grant FDN-167281 (H.L.); the European Research Council309548 (R.H.); the Wellcome Investigator Award 109915/Z/15/Z (R.H.); the Medical Research Council (United Kingdom) MR/N025431/1 (R.H.); the Wellcome Trust Pathfinder Scheme 201064/Z/16/Z (R.H. and H.L.); the Newton Fund (United Kingdom/Turkey) MR/N027302/1 (R.H. and H.L.); the Spanish Ministry of Economy, Industry and Competitiveness to the European Molecular Biology Laboratory (EMBL) partnership; the Centro de Excelencia Severo Ochoa; the Centres de Recerca de Catalunya (CERCA) Program/Generalitat de Catalunya; the Generalitat de Catalunya through the Department of Health and Department of Business and Knowledge; the Spanish Ministry of Economy, Industry and Competitiveness with funds from the European Regional Development Fund corresponding to the 2014 to 2020 Smart Growth Operating Program
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