Kodikologie und Paläographie zwischen Geisteswissenschaften und Informatik. Einleitung

Digitale Kodikologie und Paläographie, wie sie sich in der Tagungsreihe Maschinen und Manuskripte des Projekts eCodicology präsentierten, werden üblicherweise in interdisziplinären Projekten und multidisziplinären Forschergruppen realisiert. Ein solches Design hat Konsequenzen für die digitale Kodikologie und Paläographie. Unsere Einführung beschreibt und systematisiert, wie mit dieser Situation bei den in diesem Band präsentierten Vorhaben umgegangen wird. Dabei zeigen sich Momente, die als ›zusammengesetzte‹ oder ›ergänzende‹ Interdisziplinarität verstanden werden können

Aktienbasierte Langfristanreize im Rahmen der Vorstandsverguetung: Evidenz auf Basis Deutscher Prime Standard Unternehmen

While in the US stock-based incentives are commonly used since the 50s of the last century, in Germany they were invented only some ten years ago. Even in 1996 firms faced considerable regulatory difficulties when willing to grant such incentives. In the meantime the legal environment has changed significantly and today even the German Corporate Governance Code encourages firms to grant stock-based long-term incentives. However, examining a hand-collected unique data-set we find that even only 37% of all German Prime Standard firms have used stock-based long-term incentives in 2006. In these firms stock-based long-term incentives account for less that 23% of the overall compensation to members of the management board. Our empirical analysis reveals that in particular large firms with high RnD expenditures, substantial opaqueness and high free-float are likely to grant stock-based long-term incentives. Furthermore, we find that high inside ownership and large blockholders are negatively correlated with the probability of granting stock-based long-term incentives. Finally, we find that an externally hired CEO increases the likelihood of stock-based incentives, in particularly if the chairman of the supervisory board is a former executive of the firm. In sum, our evidence is consistent with the view that shareholders use stock-based incentives as a governance mechanism to mitigate the agency problem in complex firms with high information asymmetry. --executive compensation,incentives,corporate governance,Germany

Regression methods for ophthalmic glucose sensing using metamaterials

We present a novel concept for in vivo sensing of glucose using metamaterials in combination with automatic learning systems. In detail, we use the plasmonic analogue of electromagnetically induced transparency (EIT) as sensor and evaluate the acquired data with support vector machines. The metamaterial can be integrated into a contact lens. This sensor changes its optical properties such as reflectivity upon the ambient glucose concentration, which allows for in situ measurements in the eye. We demonstrate that estimation errors below 2% at physiological concentrations are possible using simulations of the optical properties of the metamaterial in combination with an appropriate electrical circuitry and signal processing scheme. In the future, functionalization of our sensor with hydrogel will allow for a glucose-specific detection which is insensitive to other tear liquid substances providing both excellent selectivity and sensitivity

Exposure of patients to di(2-ethylhexy)phthalate (DEHP) and its metabolite MEHP during extracorporeal membrane oxygenation (ECMO) therapy

The plasticizer di(2-ethylhexyl)phthalate (DEHP) is often used for PVC medical devices, that are also largely used for intensive care medical treatments, like extracorporeal membrane oxygenation (ECMO) therapy. Due to the toxicological potential of DEHP, the inner exposure of patients with this plasticizer is a strong matter of concern as many studies have shown a high leaching potential of DEHP into blood. In this study, the inner DEHP exposure of patients undergoing ECMO treatment was investigated. The determined DEHP blood levels of ECMO patients and the patients of the control group ranged from 31.5 to 1009 μg/L (median 156.0 μg/L) and from 19.4 to 75.3 μg/L (median 36.4 μg/L), respectively. MEHP blood levels were determined to range from < LOD to 475 μg/L (median 15.9 μg/L) in ECMO patients and from < LOD to 9.9 μg/L (median 3.7 μg/L) in the control group patients, respectively. Increased DEHP exposure was associated with the number of cannulas and membranes of the ECMO setting, whereas residual diuresis decreased the exposure. Due to the suspected toxicological potential of DEHP, its use in medical devices should be further investigated, in particular for ICU patients with long-term exposure to PVC, like in ECMO therapy

Gravity-wave-induced cross-isentropic mixing: a DEEPWAVE case study

Orographic gravity waves (i.e., mountain waves) can potentially lead to cross-isentropic fluxes of trace gases via the generation of turbulence. During the DEEPWAVE (Deep Propagating Gravity Wave Experiment) campaign in July 2014, we performed tracer measurements of carbon monoxide (CO) and nitrous oxide (N2O) above the Southern Alps during periods of gravity wave activity. The measurements were taken along two stacked levels at 7.9 km in the troposphere and 10.9 km in the stratosphere. A detailed analysis of the observed wind components shows that both flight legs were affected by vertically propagating gravity waves with momentum deposition and energy dissipation between the two legs. Corresponding tracer measurements indicate turbulent mixing in the region of gravity wave occurrence. For the stratospheric data, we identified mixing leading to a change of the cross-isentropic tracer gradient of N2O from the upstream to the downstream region of the Southern Alps. Based on the quasi-inert tracer N2O, we identified two distinct layers in the stratosphere with different chemical composition on different isentropes as given by constant potential temperature 2. The CO–N2O relationship clearly indicates that irreversible mixing between these two layers occurred. Further, we found a significant change of the vertical profiles of N2O with respect to 2 from the upstream to the downstream side above the Southern Alps just above the tropopause. A scale-dependent gradient analysis reveals that this cross-isentropic gradient change of N2O is triggered in the region of gravity wave occurrence

Fight and air exposure times of caught and released salmonids from the South Fork Snake River

Catch-and-release regulations are among the most common types of fishing regulations. In recent years, concerns have arisen regarding the exposure of fish to air during catch-and-release angling. The purpose of our study was to quantify the length of time angled fish were exposed to air by anglers in a typical catch-and-release fishery and relate it to the lengths of time reported to produce negative effects. In total, 312 individual anglers were observed on the South Fork Snake River, Idaho, from May through August 2016. Fight time varied from 1.1 s to 230.0 s, and average fight time was 40.0 s (SD=36.8). Total air exposure times varied from 0.0 s to 91.8 s and averaged 19.3 s (SD=15.0). Though not statistically significant, a trend in reduced fight times was observed when anglers were guided and increased air exposure times when a net was used and a picture was taken. Results of the current study suggest that anglers expose fish to air for periods that are much less than those reported to cause mortality

Acute Muscular Sarcocystosis: An International Investigation Among Ill Travelers Returning From Tioman Island, Malaysia, 2011-2012

A large outbreak of acute muscular sarcocystosis (AMS) among international tourists who visited Tioman Island, Malaysia, is described. Clinicians evaluating travelers returning ill from Malaysia with myalgia, with or without fever, should consider AMS in their differential diagnosi

The COVID-19 Vaccine Communication Handbook. A practical guide for improving vaccine communication and fighting misinformation

This handbook is for journalists, doctors, nurses, policy makers, researchers, teachers, students, parents – in short, it’s for everyone who wants to know more about the COVID-19 vaccines, how to talk to others about them, how to challenge misinformation about the vaccines. This handbook is self-contained but additionally provides access to a “wiki” of more detailed information

Photography-based taxonomy is inadequate, unnecessary, and potentially harmful for biological sciences

The question whether taxonomic descriptions naming new animal species without type specimen(s) deposited in collections should be accepted for publication by scientific journals and allowed by the Code has already been discussed in Zootaxa (Dubois & Nemésio 2007; Donegan 2008, 2009; Nemésio 2009a–b; Dubois 2009; Gentile & Snell 2009; Minelli 2009; Cianferoni & Bartolozzi 2016; Amorim et al. 2016). This question was again raised in a letter supported by 35 signatories published in the journal Nature (Pape et al. 2016) on 15 September 2016. On 25 September 2016, the following rebuttal (strictly limited to 300 words as per the editorial rules of Nature) was submitted to Nature, which on 18 October 2016 refused to publish it. As we think this problem is a very important one for zoological taxonomy, this text is published here exactly as submitted to Nature, followed by the list of the 493 taxonomists and collection-based researchers who signed it in the short time span from 20 September to 6 October 2016