Undergraduate Research: Importance, Benefits, and Challenges

Developing and maintaining undergraduate research programs benefits students, faculty mentors, and the university. Incorporating a research component along with a sound academic foundation enables students to develop independent critical thinking skills along with oral and written communication skills. The research process impacts valuable learning objectives that have lasting influence as undergraduates prepare for professional service. Faculty members at teaching intensive institutions can enhance learning experiences for students while benefiting from a productive research agenda. The university in turn benefits from presentations and publications that serve to increase visibility in the scientific community. Whether projects are derived through student-generated or mentor-generated means, students benefit from completion of exposure to the hypothesis-driven scientific method

Presence of Observers Increases One Repetition Maximum in College-age Males and Females

Purpose: To determine if the presence of observers affects muscular strength performance in college-age males and females. Methods: Twenty-five women and 24 men participated in the study. Two counter-balanced trials were performed in which participants completed 1-RM tests in bench press and leg press. During one trial, two members of the opposite gender observed the 1-RM tests. During the other trial there were no observers, other than the tester. Results: 1-RM for females increased 3.4±0.8 lbs on bench press (p\u3c.001) and increased 9.2±3.8 lbs on leg press (p=.025) when observers were present. 1-RM for males increased 4.2±1.1 lbs on bench press (p=.001) and increased 18.8±5.2 lbs on leg press (p=.002) with observers present. There was no difference in the percent increase in 1-RM between males and females for either leg press (p=.71) or bench press (p=.08). Conclusion: College-age males and females lifted more weight during a 1-RM test when observers were present

Self-estimation of Body Fat is More Accurate in College-age Males Compared to Females

Objective: To determine the effect of gender on the ability to accurately estimate one’s own body fat percentage. Participants: Fifty-five college-age males and 99 college-age females Methods: Participants estimated their own body fat percent before having their body composition measured using a BOD POD. Participants also completed a modified Social Physique Anxiety Scale (SPAS). Results: Estimated body fat was significantly lower compared to measured body fat percent in females (26.8±5.6% vs. 30.2±7.0%, p\u3c0.001) but not in males (16.8±6.8% vs. 18.1±8.3%, p=0.09). The mean difference between estimated and measured body fat was significantly higher for females compared to males (p\u3c0.001). There was a moderate, significant correlation found between measured body fat percent and SPAS score for males (r=0.331, p=0.014) and females (r=.427, p\u3c0.001). Conclusions: Males estimated their body fat percent more accurately than females. Despite these findings, 62% of males and 76% of females underestimated their body fat

Type of Encouragement Influences Peak Muscle Force in College-Age Women

Purpose: To investigate if the type of encouragement during a maximal voluntary isometric contraction (MVIC) had an influence on peak muscle force in strength-trained versus untrained collegiate women. Methods: Eleven strength-trained (20.4 + 1 yr) and twelve untrained (20.8 + 1 yr) women participated in three, five-second MVICs of seated knee extension. The three trials consisted of verbal only encouragement, verbal + visual encouragement, and verbal + pain avoidance encouragement. In all three trials, the participants received the same verbal encouragement. Trials were counterbalanced to minimize any possible order effects. A repeated measure ANOVA was used to analyze data. Any significant main effects were further analyzed using Tukey post hoc tests. Results: There was no interaction between training status and encouragement type for all subjects F(2,42) = 1.5474, p = 0.22). For all subjects, a main effect for encouragement type was detected (F(2,42) = 6.616, p \u3c0.05) with significant differences found in MVIC between the verbal encouragement and verbal + visual feedback (99.5±29 ft-lbs and 115.6±29 ft-lbs, p\u3c0.01). No significant differences were found between the verbal only and the addition of pain avoidance (99.5±29 ft-lbs and 109.9±26.3 ft-lbs, p=0.069) or the visual and pain avoidance trials (115.6±29 ft-lbs and 109.9±26 ft-lbs, p=0.43). Conclusion: In this study, training status did not significantly influence the response to type of encouragement. Individuals produced the most force during a MVIC with verbal and visual encouragement. The incorporation of verbal encouragement and visual feedback is an important factor in eliciting peak force in college-aged women. This may have important implications in training and rehabilitation models that incorporate resistive loading of the skeletal muscles

Upper Body Muscular Activation during Variations of Push-Ups in Healthy Men

International Journal of Exercise Science 6(4) : 278-288, 2013. The purpose of this study was to assess neural activity for upper body musculature in college-age men during repetitions of a conventional pushup or a Perfect PushupTM. Eighteen healthy men (21.6±1 yr, 182.5±7 cm, 87.4±15 kg) completed five repetitions of a conventional pushup and Perfect PushupTM while using a wide hand base of support for the upper body. Body position, hand placement, and cadence of the pushup were standardized. Root mean square electromyography (RMS-EMG, mV/Sec) was collected for the triceps brachii (TB), pectoralis major (PM), serratus anterior (SA), and posterior deltoid (PD) during all repetitions. RMS-EMG values were normalized to a maximal voluntary isometric contraction in the pushup position (%MVICPU). For each muscle, %MVICPU for repetitions 1, 3, and 5 were analyzed for differences due to type of push-up. No differences in %MVICPU due to type ofpush-up for the TB (p=0.079) or the SA (p=0.45) were detected. The Perfect PushupTM increased %MVICPU compared to the conventional pushup (44%, p\u3c0.05). Additionally, the Perfect PushupTM increased %MVICPU by the third repetition (p\u3c0.05) while the conventional pushup did not until the 5th repetition. The conventional pushup activated more PD (76%, p\u3c0.05). The type of push-up that requires the greatest neural activity for a given number of repetitions should result in improved adaptations. The Perfect PushupTM was superior for activating the pectoralis major while individuals would elicit more neural activation in the posterior deltoid by conventional push-ups. Trainers and rehabilitation specialists should consider these data when attempting to train or isolate upper body skeletal muscles using a push-up movement

Effects of Prior Fasting on Fat Oxidation during Resistance Exercise

International Journal of Exercise Science 11(2): 827-833, 2018. Prior research has demonstrated that the percentage of fuel utilization contributed by CHO compared to fat rises with an increase in exercise intensity. The role of food intake prior to exercise has been well studied and fasting prior to exercise generally increases reliance on fat as fuel. However, data on the role of fasting prior to resistance exercise is limited. Therefore, the purpose of this study was to assess the effects of one bout of resistance training in a fasted state compared to ingestion of standardized meal on fat and carbohydrate utilization. Twelve female (n = 12, age = 20.1 ± 0.79 yrs, height = 67.0 ± 2.63 in, weight = 143 ± 21.8 lbs) NCAA Division 1 athletes participated in the study. Each participant completed one 10 hour fasted resistance training session and one postprandial resistance training session. The respiratory exchange ratio (RER) and METs were measured using a Cosmed K4b2portable metabolic cart (Cosmed, Rome, Italy) and heart rate was measured by a Polar H1 heart rate monitor. Participants consumed the prescribed food, waited 15 minutes, and then completed three sets of five repetitions of bench press, back squat, and military press at 60% of their 1-repetition maximum. The mean fasted RER was significantly lower than postprandial for back squat (p=0.01) and military press (p=0.02), but not bench press (p=0.19). There was no difference in METs, RPE, or HR between fasted and postprandial trials for any exercise. Results suggest that fasted resistance exercise relies more heavily on fat metabolism than carbohydrate

The concept of anorexia of aging in late life depression:A cross-sectional analysis of a cohort study.

INTRODUCTION: Anorexia of aging (AA) is classically associated with depression. However, robust evidence is lacking regarding general clinic populations. Our aim was to evaluate the association between AA and major depressive disorder (MDD) in geriatric outpatients from a middle-income country. METHODS: We conducted a cross-sectional analysis of a cohort study. MDD diagnosis was assessed with a psychiatric interview (SCID-5-CV) according to DSM-5 criteria. Depressive symptomatology was assessed by a 15-items Geriatric Depression Scale (GDS) and the PHQ-9 questionnaire. Appetite was measured with the Simple Nutrition Appetite Questionnaire (SNAQ), whereas AA was defined as a SNAQ score ≤13 points). Linear and logistic regression analysis adjusted for potential confounders were applied to assess the association between depressive symptomatology, MDD and AA. RESULTS: Of the total 339 participants, MDD was present in 65. AA was more frequent in patients with MDD compared to non-depressed patients (30.7 versus 7.7%; p<0.001). The SNAQ score was lower in depressed patients (14.5 vs. 16.6, p<0.001). Adjusted for confounding, linear and logistic regression showed a significant association between the GDS score, PHQ-9 score and MDD with the SNAQ score (p<0.001) and cut-off representing AA (p<0.001), respectively. Moreover, MDD and AA interacted significantly with their association with weight loss (p<0.001). CONCLUSIONS: Depression scales (even without somatic complaints) and MDD were associated with AA in geriatric outpatients. AA is associated with weight loss in MDD. Prospective studies should expand these findings

Clinical field-strength MRI of amyloid plaques induced by low-level cholesterol feeding in rabbits

Two significant barriers have limited the development of effective treatment of Alzheimer's disease. First, for many cases the aetiology is unknown and likely multi-factorial. Among these factors, hypercholesterolemia is a known risk predictor and has been linked to the formation of β-amyloid plaques, a pathological hallmark this disease. Second, standardized diagnostic tools are unable to definitively diagnose this disease prior to death; hence new diagnostic tools are urgently needed. Magnetic resonance imaging (MRI) using high field-strength scanners has shown promise for direct visualization of β-amyloid plaques, allowing in vivo longitudinal tracking of disease progression in mouse models. Here, we present a new rabbit model for studying the relationship between cholesterol and Alzheimer's disease development and new tools for direct visualization of β-amyloid plaques using clinical field-strength MRI. New Zealand white rabbits were fed either a low-level (0.125–0.25% w/w) cholesterol diet (n = 5) or normal chow (n = 4) for 27 months. High-resolution (66 × 66 × 100 µm3; scan time = 96 min) ex vivo MRI of brains was performed using a 3-Tesla (T) MR scanner interfaced with customized gradient and radiofrequency coils. β-Amyloid-42 immunostaining and Prussian blue iron staining were performed on brain sections and MR and histological images were manually registered. MRI revealed distinct signal voids throughout the brains of cholesterol-fed rabbits, whereas minimal voids were seen in control rabbit brains. These voids corresponded directly to small clusters of extracellular β-amyloid-positive plaques, which were consistently identified as iron-loaded (the presumed source of MR contrast). Plaques were typically located in the hippocampus, parahippocampal gyrus, striatum, hypothalamus and thalamus. Quantitative analysis of the number of histologically positive β-amyloid plaques (P < 0.0001) and MR-positive signal voids (P < 0.05) found in cholesterol-fed and control rabbit brains corroborated our qualitative observations. In conclusion, long-term, low-level cholesterol feeding was sufficient to promote the formation of extracellular β-amyloid plaque formation in rabbits, supporting the integral role of cholesterol in the aetiology of Alzheimer's disease. We also present the first evidence that MRI is capable of detecting iron-associated β-amyloid plaques in a rabbit model of Alzheimer's disease and have advanced the sensitivity of MRI for plaque detection to a new level, allowing clinical field-strength scanners to be employed. We believe extension of these technologies to an in vivo setting in rabbits is feasible and that our results support future work exploring the role of MRI as a leading imaging tool for this debilitating and life-threatening disease

Measurement of the quasi-elastic axial vector mass in neutrino-oxygen interactions

The weak nucleon axial-vector form factor for quasi-elastic interactions is determined using neutrino interaction data from the K2K Scintillating Fiber detector in the neutrino beam at KEK. More than 12,000 events are analyzed, of which half are charged-current quasi-elastic interactions nu-mu n to mu- p occurring primarily in oxygen nuclei. We use a relativistic Fermi gas model for oxygen and assume the form factor is approximately a dipole with one parameter, the axial vector mass M_A, and fit to the shape of the distribution of the square of the momentum transfer from the nucleon to the nucleus. Our best fit result for M_A = 1.20 \pm 0.12 GeV. Furthermore, this analysis includes updated vector form factors from recent electron scattering experiments and a discussion of the effects of the nucleon momentum on the shape of the fitted distributions.Comment: 14 pages, 10 figures, 6 table

Opposite-side flavour tagging of B mesons at the LHCb experiment

The calibration and performance of the oppositeside flavour tagging algorithms used for the measurements of time-dependent asymmetries at the LHCb experiment are described. The algorithms have been developed using simulated events and optimized and calibrated with B + →J/ψK +, B0 →J/ψK ∗0 and B0 →D ∗− μ + νμ decay modes with 0.37 fb−1 of data collected in pp collisions at √ s = 7 TeV during the 2011 physics run. The oppositeside tagging power is determined in the B + → J/ψK + channel to be (2.10 ± 0.08 ± 0.24) %, where the first uncertainty is statistical and the second is systematic