Artificial intelligence and smart vision for building and construction 4.0: Machine and deep learning methods and applications

This article presents a state-of-the-art review of the applications of Artificial Intelligence (AI), Machine Learning (ML), and Deep Learning (DL) in building and construction industry 4.0 in the facets of architectural design and visualization; material design and optimization; structural design and analysis; offsite manufacturing and automation; construction management, progress monitoring, and safety; smart operation, building management and health monitoring; and durability, life cycle analysis, and circular economy. This paper presents a unique perspective on applications of AI/DL/ML in these domains for the complete building lifecycle, from conceptual stage, design stage, construction stage, operational and maintenance stage until the end of life. Furthermore, data collection strategies using smart vision and sensors, data cleaning methods (post-processing), data storage for developing these models are discussed, and the challenges in model development and strategies to overcome these challenges are elaborated. Future trends in these domains and possible research avenues are also presented

Palaeogenomic analysis of black rat (Rattus rattus) reveals multiple European introductions associated with human economic history

The distribution of the black rat (Rattus rattus) has been heavily influenced by its association with humans. The dispersal history of this non-native commensal rodent across Europe, however, remains poorly understood, and different introductions may have occurred during the Roman and medieval periods. Here, in order to reconstruct the population history of European black rats, we first generate a de novo genome assembly of the black rat. We then sequence 67 ancient and three modern black rat mitogenomes, and 36 ancient and three modern nuclear genomes from archaeological sites spanning the 1st-17th centuries CE in Europe and North Africa. Analyses of our newly reported sequences, together with published mitochondrial DNA sequences, confirm that black rats were introduced into the Mediterranean and Europe from Southwest Asia. Genomic analyses of the ancient rats reveal a population turnover in temperate Europe between the 6th and 10th centuries CE, coincident with an archaeologically attested decline in the black rat population. The near disappearance and re-emergence of black rats in Europe may have been the result of the breakdown of the Roman Empire, the First Plague Pandemic, and/or post-Roman climatic cooling.Peer reviewe

The dominant Anopheles vectors of human malaria in the Asia-Pacific region: occurrence data, distribution maps and bionomic précis

<p>Abstract</p> <p>Background</p> <p>The final article in a series of three publications examining the global distribution of 41 dominant vector species (DVS) of malaria is presented here. The first publication examined the DVS from the Americas, with the second covering those species present in Africa, Europe and the Middle East. Here we discuss the 19 DVS of the Asian-Pacific region. This region experiences a high diversity of vector species, many occurring sympatrically, which, combined with the occurrence of a high number of species complexes and suspected species complexes, and behavioural plasticity of many of these major vectors, adds a level of entomological complexity not comparable elsewhere globally. To try and untangle the intricacy of the vectors of this region and to increase the effectiveness of vector control interventions, an understanding of the contemporary distribution of each species, combined with a synthesis of the current knowledge of their behaviour and ecology is needed.</p> <p>Results</p> <p>Expert opinion (EO) range maps, created with the most up-to-date expert knowledge of each DVS distribution, were combined with a contemporary database of occurrence data and a suite of open access, environmental and climatic variables. Using the Boosted Regression Tree (BRT) modelling method, distribution maps of each DVS were produced. The occurrence data were abstracted from the formal, published literature, plus other relevant sources, resulting in the collation of DVS occurrence at 10116 locations across 31 countries, of which 8853 were successfully geo-referenced and 7430 were resolved to spatial areas that could be included in the BRT model. A detailed summary of the information on the bionomics of each species and species complex is also presented.</p> <p>Conclusions</p> <p>This article concludes a project aimed to establish the contemporary global distribution of the DVS of malaria. The three articles produced are intended as a detailed reference for scientists continuing research into the aspects of taxonomy, biology and ecology relevant to species-specific vector control. This research is particularly relevant to help unravel the complicated taxonomic status, ecology and epidemiology of the vectors of the Asia-Pacific region. All the occurrence data, predictive maps and EO-shape files generated during the production of these publications will be made available in the public domain. We hope that this will encourage data sharing to improve future iterations of the distribution maps.</p

Robust estimation of bacterial cell count from optical density

Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals &lt;1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data

The Discovery and Excavation of a Human Burial from the Mini-athiliya Shell Midden in Southern Sri Lanka

Several shell middens of coastal Sri Lanka indicate human occupation in the mid-Holocene and are recognized as being of prime importance in the archaeological narrative of the island. A salvage archaeology operation conducted at the Mini-athiliya shell midden in the Southern Province of Sri Lanka, yielded ancient human remains associated with stone implements and culturally modified faunal remains. The main objective of this rescue operation was to mitigate the destruction to this archaeological site. We report the excavation strategy and dating of this mid-Holocene shell midden, while focusing on the discovery and extraction of a complete human burial that had not been disturbed by the shell mining activity at the site. This excavation is intended to serve as a precursor to systematic investigation of the coastal shell middens of southern Sri Lanka. </div

Rigid Barrier with a Gabion Cushion Subjected to Boulder Impact

© 2019 Jude Shalitha Perera Pethati Mudiyanselage DonProtection against rockfalls occurring alongside landslides contribute to the major part of the disaster management budget in many counties like Switzerland, Japan and Hongkong. Protective structures are usually built over disaster trajectories to safeguard lives and properties. Reinforced concrete barriers that are fitted with gabions are one common form of installations to provide the protection. Few experimental investigations involving impact testings of a rigid reinforced concrete barrier which was fitted with a gabion cushion cover have been reported in the literature. But these investigations were limited to studying the localised actions of impact. The change of structural response behaviour of the barrier as a whole by the presence of a cushion layer is typically not within the scope of the reported investigations. Design methodologies that have been developed are typically limited to overly simplified calculations based on applying an equivalent static force to the barrier. To fill this knowledge gap full-scale pendulum tests have been conducted by the authors on a barrier that was fitted with a gabion cushion layer. The structural response behaviour of the barrier, contact force and tensile strains in the longitudinal reinforcement were of interests. Results recorded from the tests were compared with results from control experiments which were without the protection of any cushion materials. The introduction of a layer of cushion is shown to be able to have the deflection demand on the structure reduced by more than 70% when the amount of energy delivered by the impact is kept constant. An analytical procedure employing the Hunt and Crossley contact model, Swiss code model and two-degrees-of-freedom (2DOF) system modelling technique is presented for evaluating the flexural response demand behaviour of the cushioned barrier. The proposed analytical procedure is shown to be able to predict the reduced deflection demand with a reasonable degree of conservatism. At the end of the thesis, a simple hand calculation procedure featuring the use of design charts is presented for engineering applications. The procedure is illustrated by a worked example which is based on a realistic rockfall scenario

Out of Context, in Association: Human Remains Salvaged from the Mini-athiliya Shell Midden, Sri Lanka

The skeletal evidence for early modern human occupation of South Asia is sparse. Sri Lanka has been occupied by modern humans from the terminal Pleistocene, with a skeletal record indicating continuity of occupation and settlement into the late Holocene. This study focuses on the analysis of fragmented human remains dated to the mid-Holocene recovered from a salvage archaeology operation conducted at a shell midden in the coastal village of Mini-athiliya in southern Sri Lanka. The Mini-athiliya site has been radiocarbon dated to ca. 3600 b.p. Large quantities of estuarine, marine, and terrestrial shells, stone tools, lithic debris, and animal bones were associated with the human skeletal remains recovered from this shell midden. The skeletal remains, faunal remains, and stone tools from this site have been greatly disturbed by recent shell mining activities. Much of the material collected from the piles of debris was mixed, fragmented, and out of context.Our study refers to associations we make to the cultural assemblage from this site to make inferences on the context of skeletal remains found. The minimum number of individuals (MNI) identified from commingled remains is five. In addition, another individual from an undisturbed context from this site was previously reported. Based on tooth eruption and the presence and level of dental attrition, the estimated age at death for these individuals ranges from 5 to 45 years. Heavy attrition in the adult dentition indicates a highly abrasive diet with a marked absence of caries among these relatively robust people. This study contributes to the understanding of the bioarchaeological aspects of mid-Holocene aquatic foragers who were contemporaries of early agricultural people of South Asia, while describing a framework for managing a skeletal sample from a disturbed context

Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases

Abstract Neurodegenerative disorders are characterized by the gradual decline and irreversible loss of cognitive functions and CNS structures. As therapeutic recourse stagnates, neurodegenerative diseases will cost over a trillion dollars by 2050. A dearth of preventive and regenerative measures to hinder regression and enhance recovery has forced patients to settle for traditional therapeutics designed to manage symptoms, leaving little hope for a cure. In the last decade, pre‐clinical animal models and clinical investigations in humans have demonstrated the safety and promise of an emerging cellular product from subcutaneous fat. The adipose‐derived stromal vascular fraction (SVF) is an early intervention and late‐stage novel ‘at point’ of care cellular treatment, demonstrating improvements in clinical applications for Multiple Sclerosis, Alzheimer's disease, and Parkinson's disease. SVF is a heterogeneous fraction of cells forming a robust cellular ecosystem and serving as a novel and valuable source of point‐of‐care autologous cell therapy, providing an easy‐to‐access population that we hypothesize can mediate repair through ‘bi‐directional’ communication in response to pathological cues. We provide the first comprehensive review of all pre‐clinical and clinical findings available to date and highlight major challenges and future directions. There is a greater medical and economic urgency to innovate and develop novel cellular therapy solutions that enable the repair and regeneration of neuronal tissue that has undergone irreversible and permanent damage