44 research outputs found

    Reflexþes sobre organização e gestão na educação profissional e tecnológica: uma anålise dos elementos históricos e sociológicos

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    O presente estudo tem como objetivo discutir a organização e gestão da Educação Profissional e Tecnológica (EPT), abordando alguns dos desdobramentos históricos, sociais e legais para a efetivação da gestão democråtica no contexto educacional da EPT. Para isso, analisamos aos processos de gestão escolar e as influências patrimonialistas e gerencialistas ocorridas no contexto histórico brasileiro; posteriormente, descrevemos os fundamentos político-ideológicos da organização administrativa da escola, com foco nas relaçþes entre gestão pedagógica, administrativa e de recursos humanos e a importância destas para a transformação social; e, por fim, abordamos os elementos histórico-políticos e legais do processo democråtico no contexto escolar e os entraves existentes para a legitimação da gestão democråtica como princípio norteador das pråticas educativas e da organização escolar, com foco na EPT. Quanto a metodologia utilizada foi à revisão bibliogråfica e documental, com abordagem qualitativa de caråter descritivo-reflexiva, baseado em autores como Coutinho (2006), Fernandes (2006), Grabowski (2014), Gramsci (2007), Paro (2012) e Souza (2009). As conclusþes mostraram que a gestão escolar Ê influenciada por aspectos históricos, econômicos e político-ideológicos, na qual a classe dominante como mecanismo de conformação social, acarretando na efetivação de uma gestão democråtica formal e estÊtica, com uma visão distorcida dos princípios democråticos necessårios à transformação social no espaço escolar. Concluiu-se tambÊm que a superação dessas concepçþes tradicionais dar-se-å a partir da reflexão desses elementos em sua pråtica social, buscando elencar consideraçþes e sugestþes para se efetivar uma gestão escolar que alcance a transformação social

    Kinase Activity Profiling of Pneumococcal Pneumonia

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    Background: Pneumonia represents a major health burden. Previous work demonstrated that although the induction of inflammation is important for adequate host defense against pneumonia, an inability to regulate the host's inflammatory response within the lung later during infection can be detrimental. Intracellular signaling pathways commonly rely on activation of kinases, and kinases play an essential role in the regulation of the inflammatory response of immune cells. Methodology/Principal Findings: Pneumonia was induced in mice via intranasal instillation of Streptococcus (S.) pneumoniae. Kinomics peptide arrays, exhibiting 1024 specific consensus sequences for protein kinases, were used to produce a systems biology analysis of cellular kinase activity during the course of pneumonia. Several differences in kinase activity revealed by the arrays were validated in lung homogenates of individual mice using western blot. We identified cascades of activated kinases showing that chemotoxic stress and a T helper 1 response were induced during the course of pneumococcal pneumonia. In addition, our data point to a reduction in WNT activity in lungs of S. pneumoniae infected mice. Moreover, this study demonstrated a reduction in overall CDK activity implying alterations in cell cycle biology. Conclusions/Significance: This s

    Observation of long-range, near-side angular correlations in proton-proton collisions at the LHC

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    This is the pre-print version of the Published Article, which can be accessed from the link below - Copyright @ 2010 Springer VerlagResults on two-particle angular correlations for charged particles emitted in proton-proton collisions at center-of-mass energies of 0.9, 2.36, and 7 TeV are presented, using data collected with the CMS detector over a broad range of pseudorapidity (eta) and azimuthal angle (phi). Short-range correlations in Delta(eta), which are studied in minimum bias events, are characterized using a simple "independent cluster" parametrization in order to quantify their strength (cluster size) and their extent in eta (cluster decay width). Long-range azimuthal correlations are studied differentially as a function of charged particle multiplicity and particle transverse momentum using a 980 inverse nb data set at 7 TeV. In high multiplicity events, a pronounced structure emerges in the two-dimensional correlation function for particle pairs with intermediate transverse momentum of 1-3 GeV/c, 2.0< |Delta(eta)| <4.8 and Delta(phi) near 0. This is the first observation of such a long-range, near-side feature in two-particle correlation functions in pp or p p-bar collisions

    Strange Particle Production in pp Collisions at sqrt(s) = 0.9 and 7 TeV

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    Observation of long-range, near-side angular correlations in proton-proton collisions at the LHC

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    Results on two-particle angular correlations for charged particles emitted in proton-proton collisions at center-of-mass energies of 0.9, 2.36, and 7TeV are presented, using data collected with the CMS detector over a broad range of pseudorapidity (eta) and azimuthal angle (phi). Short-range correlations in Delta(eta), which are studied in minimum bias events, are characterized using a simple "independent cluster" parametrization in order to quantify their strength (cluster size) and their extent in eta (cluster decay width). Long-range azimuthal correlations are studied differentially as a function of charged particle multiplicity and particle transverse momentum using a 980 nb(-1) data set at 7TeV. In high multiplicity events, a pronounced structure emerges in the two-dimensional correlation function for particle pairs with intermediate p(T) of 1-3 GeV/c, 2.
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