6,051 research outputs found

    Moral perfectionism and democratic responsiveness: reading Cavell with Foucault

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    Starting from existing interpretations of Cavell's account of moral perfectionism, this article seeks to elaborate an account of democratic responsiveness that foregrounds notions of 'turning' and 'manifesting for another'. In contrast to readings of Cavell that privilege reason-giving, the article draws on the writings of Cavell as well as on Foucault's work on parrēsia to elaborate a grammar of responsiveness that is attentive to a wider range of practices, forms of embodiment and modes of subjectivity. The article suggests that a focus on the notions of 'turning' and 'manifesting for another' is crucial if we are to account for the processes through which political imagination is opened up so as to bring about novel ways of being and acting. The arguments are illustrated with reference to recent events in the Arab Spring as well as to the politics of redress in a posttransitional social movement, Khulumani

    A synthetic biology approach for consistent production of plant-made recombinant polyclonal antibodies against snake venom toxins

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    Antivenoms developed from the plasma of hyperimmunized animals are the only effective treatment available against snakebite envenomation but shortage of supply contributes to the high morbidity and mortality toll of this tropical disease. We describe a synthetic biology approach to affordable and cost-effective antivenom production based on plant-made recombinant polyclonal antibodies (termed pluribodies). The strategy takes advantage of virus superinfection exclusion to induce the formation of somatic expression mosaics in agroinfiltrated plants, which enables the expression of complex antibody repertoires in a highly reproducible manner. Pluribodies developed using toxin-binding genetic information captured from peripheral blood lymphocytes of hyperimmunized camels recapitulated the overall binding activity of the immune response. Furthermore, an improved plant-made antivenom (plantivenom) was formulated using an in vitro selected pluribody against Bothrops asper snake venom toxins and has been shown to neutralize a wide range of toxin activities and provide protection against lethal venom doses in mice.Fil: Julve Parreño, Jose Manuel. Universidad Politécnica de Valencia; EspañaFil: Huet, Estefanía. Universidad Politécnica de Valencia; EspañaFil: Fernández del Carmen, Asun. Universidad Politécnica de Valencia; EspañaFil: Segura, Alvaro. Universidad de Costa Rica; Costa RicaFil: Venturi, Micol. Universidad Politécnica de Valencia; EspañaFil: Gandía, Antoni. Universidad Politécnica de Valencia; EspañaFil: Pan, Wei-Song. Universidad Politécnica de Valencia; EspañaFil: Albaladejo, Irene. Universidad Politécnica de Valencia; EspañaFil: Forment, Javier. Universidad Politécnica de Valencia; EspañaFil: Pla, Davinia. Instituto de Biomedicina de Valencia; EspañaFil: Wigdorovitz, Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Genética; ArgentinaFil: Calvete, Juan J.. Instituto de Biomedicina de Valencia; EspañaFil: Gutiérrez, Carlos. Universidad de Las Palmas de Gran Canaria; EspañaFil: Gutiérrez, José María. Universidad de Costa Rica; Costa RicaFil: Granell, Antonio. Universidad Politécnica de Valencia; EspañaFil: Orzáez, Diego. Universidad Politécnica de Valencia; Españ

    Truth

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    In his final works, Foucault explains his overall project as a “history of truth” centered on the relations between subjectivity and truth. While the early archaeology focuses primarily on the formation of new objects and discourses of knowledge, and later, genealogy on techniques of power, the problematic of truth is the overriding framework through which Foucault develops these analyses. Throughout all of his work, in fact, Foucault’s question is how discourse, institutions, politics, and subjects are established within regimes of truth

    El hombre como ser inacabado

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    El presente trabajo parre de la base de que una de las principales tareas de la Filosofía de la Educación consiste en la fundamentación radical de los procesos y de los resultados educativos. El núcleo de su desarrollo se centra en demos tras que el incabamiento humano es uno de los principales aspectos que fundamentan la necesidad de la educación. Tras esclarecer el inacabamiento desde las perspectivas biológica, psicológica y filosófica, se concluye, en una segunda parre, con el análisis de las repercusiones que pueden derivarse para la empresa educativa del hecho de estar constituido el hombre como un ser inacabado

    Pennsylvania Folklife Vol. 40, No. 1

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    • Square Notching in the Log Carpentry Tradition of Pennsylvania Extended • Letters from Home to a Wandering Farm Boy • Parre Schtories • Handcrafts in Lancaster County • Johann Conrad Dieffenbach of Tulpehocken • Aldes un Neies (Old and New)https://digitalcommons.ursinus.edu/pafolklifemag/1129/thumbnail.jp

    International parental migration and the psychological well-being of children in Ghana, Nigeria, and Angola

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    When parents migrate, leaving their children in the origin country, transnational families are formed. Transnational family studies on children who are “left behind” indicate that children suffer psychologically from parental migration. Many of the factors identified as affecting children's responses to parental migration however are not considered in child psychology and family sociology studies. This study aims to bridge these areas of knowledge by quantitatively investigating the association between transnational families and children's psychological well-being. It analyzes a survey conducted in three African countries in 2010–11 (Ghana N = 2760; Angola N = 2243; Nigeria N = 2168) amongst pupils of secondary schools. The study compares children in transnational families to those living with their parents in their country of origin. Children's psychological well-being is measured through the Strengths and Difficulties Questionnaire. Multiple regression analyses reveal that children in transnational families fare worse than their counterparts living with both parents but not in Ghana where living conditions mediate this relationship. This paper also looks at four characteristics of transnational families and finds that specific characteristics of transnational families and country contexts matter: (1) changing caregivers is associated with poorer well-being in all countries; (2) which parent migrates does not make a difference in Ghana, when mothers migrate and fathers are caregivers results in poorer well-being in Nigeria, and both mother's and father's migration result in worse outcomes in Angola; (3) the kin relationship of the caregiver is not associated with poorer well-being in Ghana and Nigeria but is in Angola; (4) children with parents who migrate internationally do not show different results than children whose parents migrate nationally in Ghana and Nigeria but in Angola international parental migration is associated with poorer psychological well-being. The study shows that broader characteristics in the population rather than parental migration per se are associated with decreased levels of well-being

    Nuclear Structure in Nonmesonic Weak Decay of Hypernuclei

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    A general shell model formalism for the nonmesonic weak decay of the hypernuclei has been developed.It involves a partial wave expansion of the emitted nucleon waves,preserves naturally the antisymmetrization between the escaping particles and the residual core, and contains as a particular case the weak Lambda-core coupling formalism. The hypernuclei are grouped having in view their A-1 cores, that is in those with even-even, even-odd and odd-odd cores.It is shown that in all three cases the nuclear structure manifests itself basically through Pauli Principle, and very simple expressions are derived for the neutron and proton induced decays rates, which does not involve the spectroscopic factors

    The Cladistic Technique for Territorial Studies

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    The cladistic is an technique born in the field of biology. Starting from the physics characteristics of some elements, the cladistic method try to find the hierarchical links between them in the bases of their similarity and of the research of “evidences” of relationship. The goal of this paper is to verify the potentialities of this method in the studies of the territory, in order to find correlation among different spatial areas. Considering social, economic, environmental indicators that characterise the areas of a given territory, we analyse the links between different areas, organising these links according to a hierarchical tree. The result is then compared with ones obtained using more traditional methods as multicriterial analysis, statistics and clustering.

    MARJATTA PARRE ON POISSA

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    Puheterapeutti, FM Marjatta Parre kuoli Alzheimerin taudin uuvuttamana toukokuun6. päivänä 83 vuoden iässä. Hän teki ennen eläkkeelle jäämistään pitkän päivätyönpuheterapeuttina, puheterapeuttien kouluttajana, logopedian tutkijana ja alan aktiivina
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