Paleocurrent reconstruction of the deep Pacific inflow during the middle Miocene : reflections of East Antarctic Ice Sheet growth

Today the deep western boundary current (DWBC) east of New Zealand is the most important route for deep water entering the Pacific Ocean. Large-scale changes in deep water circulation patterns are thought to have been associated with the development of the East Antarctic Ice Sheet (EAIS) close to the main source of bottom water for the DWBC. Here we reconstruct the changing speed of the southwest Pacific DWBC during the middle Miocene from ∼15.5-12.5 Ma, a period of significant global ice accumulation associated with EAIS growth. Sortable silt mean grain sizes from Ocean Drilling Program Site 1123 reveal variability in the speed of the Pacific inflow on the timescale of the 41 kyr orbital obliquity cycle. Similar orbital period flow changes have recently been demonstrated for the Pleistocene epoch. Collectively, these observations suggest that a strong coupling between changes in the speed of the deep Pacific inflow and high-latitude climate forcing may have been a persistent feature of the global thermohaline circulation system for at least the past 15 Myr. Furthermore, long-term changes in flow speed suggest an intensification of the DWBC under an inferred increase in Southern Component Water production. This occurred at the same time as decreasing Tethyan outflow and major EAIS growth between ∼15.5 and 13.5 Ma. These results provide evidence that a major component of the deep thermohaline circulation was associated with the middle Miocene growth of the EAIS and support the view that this time interval represents an important step in the development of the Neogene icehouse climate

Signal sequence insufficiency contributes to neurodegeneration caused by transmembrane prion protein

Improving the efficiency of PrP translocation into the ER decreases levels of transmembrane bound protein and rescues mice from prion disease

Patient file traceability management in a health-care complex

International audienceA large majority of health care systems are still using physical patient files in order to store administrative and medical data, medical imaging files, biological analysis results, etc. Such files are required when the patient shows up in the system for any kind of medical consultation (medical consultation with a physician, long stay in the hospital, or visit in an outpatient unit). Hence patient file traceability must be managed carefully in order to avoid file loss and improve file sorting in the archive department. This paper aims at proposing a new tool for managing patient medical file traceability and improving file sorting in order to reduce delays during delivery and globally improve quality of care. This study is part of a project conducted with the Lucien Neuwirth Cancer Institute (Saint-Etienne, France). A formal modeling of medical file flows is proposed to identify risks related to lack of traceability. A discrete-event simulation model is also proposed to test various organization scenarios related to file management outside and inside the archive department of the cancer institute. New traceability software has been implemented to support the newly proposed organization

Proposition de Loi coopérative utopique

Le séminaire juridique organisé par Coop FR en 2009 sur la simplification du droit coopératif, avait conclu à une profusion des dispositions du droit coopératif français engendrant un manque de lisibilité. Dans la droite ligne de ces travaux, une recherche a été initiée par un petit groupe de juristes coopératifs, en leur nom propre, sous la houlette de David Hiez, Professeur de droit privé à l’Université du Luxembourg, débutée en 2015 et achevée fin 2017. Elle a porté sur l'élaboration d'un droit commun coopératif plus lisible et mieux adapté aux développements du XXIème siècle. L’objet de cette recherche est de concevoir une loi coopérative idéale, non pas dans le sens où elle serait déconnectée des réalités vécues par les diverses familles, mais en ce qu'elle doit s'extraire des considérations politiques. Son ambition n'est pas d'enclencher un processus législatif mais de produire une loi coopérative plus aboutie qui pourra servir à la réflexion des chercheurs et de tous ceux qui s’intéressent au droit coopératif et, le cas échéant, de boîte à outil et être utilisée par le mouvement coopératif dans ses futures réflexions. Techniquement, l’objet de la recherche consiste dans le recensement des questions communes à toutes les familles coopératives qui seraient utilement intégrées dans la loi commune, et donc à limiter les dispositions exceptionnelles aux aspects qui révèlent une spécificité significative. La loi de 1947 est naturellement le point de départ du travail mais l'hypothèse est qu'elle mérite d'être enrichie, non seulement en intégrant des détails qu'elle ne contient pas aujourd'hui, mais aussi des questions qu'elle ne traite pas, par exemple l’organisation interne, le régime des titres de capital, la notion de groupe, le multi-sociétariat... La question de l'autonomie du droit coopératif a fait l’objet d'une attention particulière, avec l'ambition d'accroître l'autonomie par rapport au droit des sociétés, en faisant la part des liens qui méritent d'être conservés. Cette recherche est toujours en cours, le texte ici présenté n’est donc pas figé et est susceptible de modification. Les commentaires des uns ou des autres sont donc les bien venues pour l’enrichir. Vous pouvez les adresser à : [email protected]

Scalar mixing in homogeneous isotropic turbulence: A numerical study

International audienc

The Ross Sea Dipole - temperature, snow accumulation and sea ice variability in the Ross Sea region, Antarctica, over the past 2700 years

Abstract. High-resolution, well-dated climate archives provide an opportunity to investigate the dynamic interactions of climate patterns relevant for future projections. Here, we present data from a new, annually dated ice core record from the eastern Ross Sea, named the Roosevelt Island Climate Evolution (RICE) ice core. Comparison of this record with climate reanalysis data for the 1979–2012 interval shows that RICE reliably captures temperature and snow precipitation variability in the region. Trends over the past 2700 years in RICE are shown to be distinct from those in West Antarctica and the western Ross Sea captured by other ice cores. For most of this interval, the eastern Ross Sea was warming (or showing isotopic enrichment for other reasons), with increased snow accumulation and perhaps decreased sea ice concentration. However, West Antarctica cooled and the western Ross Sea showed no significant isotope temperature trend. This pattern here is referred to as the Ross Sea Dipole. Notably, during the Little Ice Age, West Antarctica and the western Ross Sea experienced colder than average temperatures, while the eastern Ross Sea underwent a period of warming or increased isotopic enrichment. From the 17th century onwards, this dipole relationship changed. All three regions show current warming, with snow accumulation declining in West Antarctica and the eastern Ross Sea but increasing in the western Ross Sea. We interpret this pattern as reflecting an increase in sea ice in the eastern Ross Sea with perhaps the establishment of a modern Roosevelt Island polynya as a local moisture source for RICE

Roosevelt Island Climate Evolution (RICE) ice core isotope record

High-resolution, well-dated climate archives provide an opportunity to investigate the dynamic interactions of climate patterns relevant for future projections. Here, we present data from a new, annually-dated ice core record from the eastern Ross Sea. Comparison of the Roosevelt Island Climate Evolution (RICE) ice core records with climate reanalysis data for the 1979-2012 calibration period shows that RICE records reliably capture temperature and snow precipitation variability of the region. RICE is compared with data from West Antarctica (West Antarctic Ice Sheet Divide Ice Core) and the western (Talos Dome) and eastern (Siple Dome) Ross Sea. For most of the past 2,700 years, the eastern Ross Sea was warming with perhaps increased snow accumulation and decreased sea ice extent. However, West Antarctica cooled whereas the western Ross Sea showed no significant temperature trend. From the 17th Century onwards, this relationship changes. All three regions now show signs of warming, with snow accumulation declining in West Antarctica and the eastern Ross Sea, but increasing in the western Ross Sea. Analysis of decadal to centennial-scale climate variability superimposed on the longer term trend reveal that periods characterised by opposing temperature trends between the Eastern and Western Ross Sea have occurred since the 3rd Century but are masked by longer-term trends. This pattern here is referred to as the Ross Sea Dipole, caused by a sensitive response of the region to dynamic interactions of the Southern Annual Mode and tropical forcings

The Ross Sea Dipole – Temperature, Snow Accumulation and Sea Ice Variability in the Ross Sea Region, Antarctica, over the Past 2,700 Years

Abstract. High-resolution, well-dated climate archives provide an opportunity to investigate the dynamic interactions of climate patterns relevant for future projections. Here, we present data from a new, annually-dated ice core record from the eastern Ross Sea. Comparison of the Roosevelt Island Climate Evolution (RICE) ice core records with climate reanalysis data for the 1979–2012 calibration period shows that RICE records reliably capture temperature and snow precipitation variability of the region. RICE is compared with data from West Antarctica (West Antarctic Ice Sheet Divide Ice Core) and the western (Talos Dome) and eastern (Siple Dome) Ross Sea. For most of the past 2,700 years, the eastern Ross Sea was warming with perhaps increased snow accumulation and decreased sea ice extent. However, West Antarctica cooled whereas the western Ross Sea showed no significant temperature trend. From the 17th Century onwards, this relationship changes. All three regions now show signs of warming, with snow accumulation declining in West Antarctica and the eastern Ross Sea, but increasing in the western Ross Sea. Analysis of decadal to centennial-scale climate variability superimposed on the longer term trend reveal that periods characterised by opposing temperature trends between the Eastern and Western Ross Sea have occurred since the 3rd Century but are masked by longer-term trends. This pattern here is referred to as the Ross Sea Dipole, caused by a sensitive response of the region to dynamic interactions of the Southern Annual Mode and tropical forcings