59 research outputs found
Waterpipe tobacco use in the United Kingdom: A cross-sectional study among university students and stop smoking practitioners
- Author
- A Grant
- Aimee Grant
- AJ Heinz
- AM Sibai
- Andy McEwen
- AS Baboor
- B Knishkowy
- Christopher Millett
- CO Cobb
- D Jackson
- D Raad
- E Sepetdjian
- EA Akl
- EA Akl
- EA Akl
- EL Sutfin
- Elham Choaie
- Elizabeth Jenkinson
- F Mzayek
- G Radwan
- G St Helen
- GM Selim
- IT Agaku
- J Khalil
- Leonie Brose
- Lion Shahab
- LS Brose
- M Jawad
- M Jawad
- M Jawad
- M Jawad
- M Jawad
- M Jawad
- M Jawad
- M Jawad
- MH Boskabady
- Mohammed Jawad
- O Dogar
- Olga Y Gorlova
- Omara Dogar
- P Jacob 3rd
- R Al Ali
- R Jaber
- R Nakkash
- RA Arrazola
- RD Goodwin
- RE Braun
- RL Fielder
- S Soneji
- SR Kumar
- T Asfar
- T Eissenberg
- T Jarrett
- T Nguyen
- W Maziak
- W Maziak
- W Maziak
- W Maziak
- Y Benjamini
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 21/12/2015
- Field of study
© 2016 Jawad et al.This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Introduction: Despite cigarette-like adverse health outcomes associated with waterpipe tobacco smoking and increase in its use among youth, it is a much underexplored research area. We aimed to measure the prevalence and patterns of waterpipe tobacco use and evaluate tobacco control policy with respect to waterpipe tobacco, in several universities across the UK. We also aimed to measure stop smoking practitioners' encounter of waterpipe tobacco smoking. Methods: We distributed an online survey to six UK universities, asking detailed questions on waterpipe tobacco. Multivariable logistic regression models, adjusted for age, gender, ethnicity, graduate status, university and socioeconomic status (SES) assessed associations between waterpipe tobacco smoking (single use and dual use with cigarettes) and sociodemographic variables. SES was ascertained by average weekly self-spend on non-essentials. We also descriptively analysed data from a 2012 survey of stop smoking practitioners to assess the proportion of clients that used waterpipe regularly. Results: f 2217 student responses, 66.0%(95% CI 63.9-68.0%) had tried waterpipe tobacco smoking; 14.3%(95% CI 12.8-15.8%) reported past-30 day use, and 8.7% (95% CI 7.6-9.9%) reported at least monthly users. Past-30 day waterpipe-only use was associated with being younger (AOR 0.95, 95% CI 0.91-0.99), male (AOR 1.44, 95% CI 1.08-1.94), higher SES (AOR 1.16, 95% CI 1.06-1.28) and belonging to non-white ethnicities (vs. white, AOR 2.24, 95% CI 1.66-3.04). Compared to less than monthly users, monthly users were significantly more likely to have urges to smoke waterpipe (28.1% vs. 3.1%,
Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study.
- Author
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- Abbas M
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- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elrasoul Y
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
BACKGROUND: Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in the availability of laparoscopic appendectomy, alternative management choices, and outcomes are poorly described. The aim was to identify variation in surgical management and outcomes of appendicitis within low-, middle-, and high-Human Development Index (HDI) countries worldwide. METHODS: This is a multicenter, international prospective cohort study. Consecutive sampling of patients undergoing emergency appendectomy over 6 months was conducted. Follow-up lasted 30 days. RESULTS: 4546 patients from 52 countries underwent appendectomy (2499 high-, 1540 middle-, and 507 low-HDI groups). Surgical site infection (SSI) rates were higher in low-HDI (OR 2.57, 95% CI 1.33-4.99, p = 0.005) but not middle-HDI countries (OR 1.38, 95% CI 0.76-2.52, p = 0.291), compared with high-HDI countries after adjustment. A laparoscopic approach was common in high-HDI countries (1693/2499, 67.7%), but infrequent in low-HDI (41/507, 8.1%) and middle-HDI (132/1540, 8.6%) groups. After accounting for case-mix, laparoscopy was still associated with fewer overall complications (OR 0.55, 95% CI 0.42-0.71, p < 0.001) and SSIs (OR 0.22, 95% CI 0.14-0.33, p < 0.001). In propensity-score matched groups within low-/middle-HDI countries, laparoscopy was still associated with fewer overall complications (OR 0.23 95% CI 0.11-0.44) and SSI (OR 0.21 95% CI 0.09-0.45). CONCLUSION: A laparoscopic approach is associated with better outcomes and availability appears to differ by country HDI. Despite the profound clinical, operational, and financial barriers to its widespread introduction, laparoscopy could significantly improve outcomes for patients in low-resource environments. TRIAL REGISTRATION: NCT02179112
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
- Author
- Aahlin EK
- Aamer A
- Aaniana K
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- Abaliksta T
- Abantanga F
- Abantanga F
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- Abd El Hameed OS
- Abd El Hamid N
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- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elmawla M
- Abd-Elrasoul Y
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- Abdel-Kader SM
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- Abdelhamed R
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- Elhelbawy MS
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- Elhusseiny AAE
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- Elkady F
- Elkelany A
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- Espinoza F
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- Leusink A
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- Liew I
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- Maciejec L
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- Madrid Barrientos LA
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- Manchego Bautista AC
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- Manfreda S
- Mangan C
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- Manipal CE
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- Marroquin Rodriguez DE
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- Menegussi J
- Mensah E
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- Merlo MS
- Mesbah N
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- Metwally MM
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- Mihaljevic AL
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- Mircea H
- Mirghani D
- Mironescu A
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- Mironescu AS
- Mirza A
- Mirza S
- Mistry A
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- Mitroudi M
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- Modolo MM
- Moe TT
- Mogan YP
- Moghazy ME
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- Mohamed A
- Mohamed AM
- Mohamed AR
- Mohamed B
- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed MA
- Mohamed MAEH
- Mohamed MM
- Mohamed O
- Mohamed SR
- Mohameden A
- Mohammad A
- Mohammad A
- Mohammed A
- Mohammed A
- Mohammed AR
- Mohammed H
- Mohammed MM
- Mohammed MMH
- Mohammed S
- Mohan H
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- Mok YT
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- Monteleone M
- Monteleone M
- Montes I
- Montes I
- Montoya Botero JA
- Montrimaite M
- Montrimaite M
- Moodley Y
- Moore R
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- Mora JJV
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- Moreira G
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- Morton R
- Mosad A
- Mosalum O
- Mostafa HA
- Mostafa M
- Mostafa M
- Mousa M
- Moussa O
- Moustafa A
- Mouttalib S
- Mowafy B
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- Mshelbwala P
- Msiska N
- Msosa V
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- Muktar U
- Mukuzunga C
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- Munipalle PC
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- Musyoka CK
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- Muzio E
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- Mykoniatis I
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- Nadkarni S
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- Nanthakumaran S
- Napolitano L
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- Narayanan R
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- Nazir M
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- Ndlovu SR
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- Negida A
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- Nepogodiev D
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- Nevieraite V
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- Nnajiuba H
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- Nwabuoku E
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- Perez Velasquez CI
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- Pesenti G
- Petrikenas S
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- Pinkney T
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- Samaraweera DI
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- Samy S
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- Sandoval Barrantes AM
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- Schivo D
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- Schultz JK
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- Scott M
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- Semeda N
- Semiz A
- Sena-Ruiz F
- Senanayake KJ
- Senanayake WSMKJ
- Setiawan J
- Seto DM
- Seyoum N
- Sfougaris D
- Sgroi G
- Shaalan M
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- Shachykava T
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- Shaharuddin S
- Shahbaz AR
- Shaheen A
- Shahine A
- Shahzad N
- Shaikh N
- Shaikh S
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- Shalabi A
- Shalaby A
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- Shamsedine AW
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- Shillito S
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- Sii SSY
- Sileri P
- Silvani P
- Silvestre BP
- Silvestri V
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- Sinha Y
- Sion M
- Sishuba N
- Sivaganesh S
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- Skehan J
- Skelly B
- Skerritt C
- Slade R
- Slapelyte E
- Sleem AS
- Sleem M
- Smart N
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- Smart N
- Smart NJ
- Smedley A
- Smith C
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- Smith D
- Snaith AC
- Snyder E
- Soares Miguel GP
- Sobnach S
- Sodde P
- Soeselo DA
- Sokratous A
- Solaini L
- Solar Garcia L
- Solar Garcia L
- Soldevila-Verdeguer C
- Soley R
- Soley R
- Soliman A
- Soliman A
- Soliman AR
- Soliman N
- Soliman NA
- Soliman S
- Soliman Y
- Sollazzo V
- Soltani N
- Som R
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- Soon WC
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- Soreide JA
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- Souaibou YI
- Souaibou YI
- Soulou V
- Spence R
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- Spence R
- Spence R
- Spence R
- Spence R
- Spina A
- Sproule L
- Spurr M
- Sreedharan A
- Srinivasan R
- Sriram A
- Sroor F
- Sruogiene EZ
- Staerkle RF
- Starr N
- Stasinou T
- Steccanella F
- Stefanopoulos A
- Stephen A
- Stewart D
- Stock S
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- Stourton F
- Strazdas A
- Strupas K
- Strupas K
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- Stuva J
- Styles K
- Suarez A
- Suarez AAB
- Subocius A
- Suleiman SI
- Summerour V
- Sund M
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- Sunderland G
- Sundstrom SM
- Suresh S
- Sutandi N
- Sutanto EPR
- Sutton P
- Sutton P
- Suyadi A
- Swann J
- Swaroop M
- Swaroop M
- Syibrah KZ
- Sykes M
- Szczap A
- Szeto CCL
- Szeto KJ-Y
- Tabiri S
- Tabiri S
- Tabiri S
- Tabiri S
- Tabiri S
- Tabiri S
- Tackie E
- Taddei A
- Tade A
- Tafazal H
- Taha EMS
- Tahboub H
- Taher AA
- Taher M
- Taher MM
- Taieb C
- Taiwo A
- Taiwo O
- Taiwo O
- Talaat M
- Tale F
- Tale L
- Talukder S
- Talukder S
- Talving P
- Talving P
- Tammam A
- Tan C
- Tan CL
- Tan CY
- Tan JJ
- Tan JK
- Tan KSK
- Tan RCK
- Tan YK
- Tan YW
- Tanase A
- Tanase A
- Tang A
- Tang L
- Tani SI
- Tansoker I
- Tarek A
- Tarek A
- Tarek D
- Targa S
- Tariq S
- Tata MD
- Tatagiba LS
- Tawfik BA
- Tawfik G
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- Taylor F
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- Teasdale E
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- Teasdale E
- Tedeschi U
- Tedjaatmadja C
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- Tew YY
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- Th'ng F
- Thabet W
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- Tham JC
- Thanusan V
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- Theodosopoulos T
- Thollot A
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- Torrance HD
- Torrance HD
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- Turkustani S
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- Tze RGE
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- Ubhi HK
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- Ukwenya Y
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- Upadhyaya V
- Upchurch E
- Urbanavicius L
- Urbina Rojas NM
- Urbonas T
- Urbonas T
- Urniezius Z
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- Usaityte A
- Uscinas L
- Utter M
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- Valioulis I
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- Venskutonis D
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- Widmer LW
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- Wild JRL
- Williams E
- Williams G
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- Wilson M
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- Winstanley J
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- Wogensen F
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- Woin E
- Wold TB
- Wolf B
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- Wondimu S
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- Wong CS
- Wong CY
- Wong F
- Wong HY
- Wood G
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- Worku M
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- Yahaya MT
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- Yeung MHA
- Yifieyeh A
- Yildirim R
- Yip C
- Ymeri S
- Yoganathan P
- Yolcu S
- Yong CO
- Yong GL
- Younis A
- Youssef D
- Youssef H
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- Zaa'treh R
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- Zapata Ponze De Leon M
- Zapata F
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- Zardab A
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- Zerihun AB
- Zeta Solis LA
- Zhang Z
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- Ziff O
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- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskiene R
- Zilinskiene R
- Zimmermann EF
- Ziubryte G
- Zohair A
- Zorrilla CD
- Zuber M
- Zuber M
- Zuk G
- Zulkifli A
- Zumbuhl L
- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans
- Author
- Abbasi Z
- Abdul-Hamid M Akhlil
- Abel Paul D
- Abrams Paul H
- Adab Fawzi A
- Adamson Andrew
- Adeyoju A
- Adolfson Jan
- Afzal Naveed
- Ahiaku Ernest K N
- Ahmed Munir
- Al Sudani Mohammed L
- Al-Samarraie Amir S M
- Al-Samerraie [Unknown]
- Al-Singary Waleed
- Al-Sudani [Unknown]
- Alcock Christopher
- Alexander Kimberly
- Ali Zulfiqar
- Almond David J
- Alonzi Roberto
- Aly Markus
- Amin Al Olama Ali
- Anderson John
- Andrews Henry
- Andrews Steven
- Anjum Iqbal
- Anson Ken
- Anyamene Nicola A
- Apakama Ike
- Aparcia F
- Archbold J A A
- Arndt Volker
- Ash D
- Ashford Richard F U
- Auvinen Anssi
- Azzabi A
- Badenoch David
- Bahl Amit
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- Barros-Silva Joao
- Barwell Julian
- Bashir J
- Basu Pradip
- Bates Christopher A
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- Bdesha Amar
- Beacock Christopher J M
- Beaney Ronald P
- Beard Ralph
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- Bhatnagar A
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- Dadaev Tokhir
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- Glass Jonathan M
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- Graham John
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- Gronberg Henrik
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- Huddart Robert
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- Humber Caroline
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- Jones Gareth
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- Joss Shelagh
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- Kachakova Darina
- Kaisary Amir
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- Kedda Mary-Anne
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- Kierzek Andrzej
- Kimber Rachel M
- Kinder R
- Kirby Roger S
- Kirk David
- Kirkbride Peter
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- Klarskov Peter
- Kluzniak Wojciech
- Kockelbergh Roger
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- Kooiman Gordon G
- Koreich O
- Kote-Jarai Zsofia
- Koupparis Anthony
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- Kraus Sigurd
- Kujala Paula
- Kujawa Magda L
- Kulkarni Ravi
- Kumar M
- Kumar Rajeev
- Kunkler Ian H
- Kynaston H
- Kynaston Howard
- Lachlan Katherine L
- Laing Robert
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- Lawson Anne
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- Leader Mary
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- Lennon Teresa
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- Lester Jason
- Leung Hing
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- Lewis J
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- Lim Hui-Yi
- Lin Hui-Yi
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- Livni Naomi
- Livsey Jacqueline
- Lloyd S
- Locke Imogen
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- Longmuir Mark
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- Madhava Kudingila R
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- Maguire Joseph
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- Matenhelia Shyam
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- McLaren Duncan
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- Michael Agnieszka
- Miller Marek
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- Mithal Natasha
- Mitkova Atanaska
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- Montgomery Bruce
- Moody Hilary
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- Morley Roland
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- Mumtaz Faiz
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- Wang Liang
- Watkin Nicholas A
- Watson M E
- Waxman J H
- Waymont Brian
- Weaver Andrew
- Webb Ralph J
- Wedderburn Andrew
- Weischer Maren
- Wells Paula
- Wemyss-Holden G D
- Weston P M T
- Wheatley Duncan
- Whelan P
- Whillis D
- Whitmore Ian
- Wiklund Fredrik
- Wilde Adam D
- Wiles Vicki
- Wilkins Marie
- Wilkinson Rosemary
- Williams John H
- Williams Simon
- Willis Michael
- Wills Michael I
- Wilson J R
- Wilson Richard
- Winkler Mathias H
- Wise Marcus
- Wokozorczyk Dominika
- Wokołorczyk Dominika
- Wood Glenn
- Woodhams Simon
- Woodhouse C
- Woodward Cathryn
- Woolf [Unknown]
- Woolfenden K A
- Worlding Jane
- Wright Mark
- Wu Huihai
- WYLIE [Unknown]
- Wylie James P
- Wynne Chris
- Yeadon Trina
- Zachariah Babu
- Zang Angelika
- Zarkar A
- Zheng Wei
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2015
- Field of study
Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have
fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in
25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16
regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of
correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP,
while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in
Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium
(LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region.
Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant
enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the
refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa,
an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of
PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent
signals within the same regio
Mortality of emergency abdominal surgery in high-, middle- and low-income countries
- Author
- A A Ahmed Ata
- A A Ibrahem
- A A Maghrabi
- A A Nasir
- A A Ne'ma Abdullah
- A Abd El Galeel
- A Abdel-Rahman Al-Aarag
- A AbdelFattah
- A Abdelgelil
- A Abdelkareem
- A Abdelmotaleb Ghazy
- A Aber
- A Abo El Magd
- A Abo Elazayem
- A Aboarab
- A Abouelnasr
- A Abouzahra
- A Adebanjo
- A Adekoya
- A Adel
- A Adel
- A Ademuyiwa
- A Adeniyi
- A Adesina
- A Adesuyi
- A Adeyeye
- A Afandy
- A Agarwal
- A Ahmed
- A Al-Mallah
- A Al-Shammari
- A Aldalaq
- A Ali
- A Ali
- A Alkammash
- A Allegri
- A Almallah
- A Almoflihi
- A Alrifaie
- A Altaf
- A Altamimi
- A Althwainy
- A Arenas
- A Ashton
- A Atef Omar
- A Austraite
- A B Zerihun
- A Badr
- A Badwy
- A Baird
- A Bamicha
- A Benevento
- A Bhangu
- A Bhargava
- A Birring
- A Boddy
- A Bondurri
- A Bonnard
- A C Manchego Bautista
- A C Manchego Bautista
- A C Roslani
- A C Snaith
- A Cacurri
- A Chambers
- A Chambers
- A Chapman
- A Chowdhury
- A Chun
- A Daltri Lazzarini Cury
- A Daqeeq
- A Das
- A Diab
- A Driscoll
- A Dubois
- A Dwydar
- A E Ajao
- A E K Musa
- A E Ward
- A Echevarria Rosas Moran
- A El Gendy
- A El Kholy
- A Elbatahgy
- A Elgebaly
- A Elkelany
- A Elkelany
- A Elkelany
- A Elkelany
- A Elkholy
- A Elshafay
- A Elwaey
- A Elwan
- A Essam Elnemr
- A Eysa
- A F Palma
- A Fadel
- A Fahiem
- A Farah
- A Faraz
- A Farquharson
- A Faure
- A Fawzy
- A Fouad
- A G N Robertson
- A Gamal Toeema
- A Garland
- A Gerosa
- A Gharib
- A Gharib
- A Gheith
- A Gomaa
- A Gouda
- A Grant
- A Gudal
- A Habeebullah
- A Hafez El-Badri Kotb
- A Hagar
- A Hammad
- A Hanks
- A Haroun
- A Hasan
- A Hasheminia
- A Hashish
- A Hassan
- A Hassan
- A Hassan
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- A Horobjowsky
- A Hussein
- A Huwait
- A J Fowler
- A Jabbar
- A Karim
- A Kenibar
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- A Khan
- A Khoja
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- A Kiasat
- A Kirishnan
- A Kirupagaran
- A Kjellin
- A Kolosov
- A Kyaw Tun
- A L Contreras Vergara
- A L Mclean
- A Lasheen
- A Leal
- A Leppäniemi
- A Livesey
- A M Afifi
- A M Altwigry
- A M Attia
- A M Elkorashy
- A M Hammad
- A M Mphatsoe
- A M Saeed
- A M Shariffuddin
- A M Warwick
- A Macdonald
- A Macfarlane
- A Maffioli
- A Mahdi
- A Maniscalco
- A Marey
- A Martin
- A Mcguigan
- A Mcphee
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- A Minocha
- A Mirza
- A Mistry
- A Mittal
- A Mohameden
- A Mohammad
- A Mohammed
- A Mohammed
- A Mokhtar
- A Morsi
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- A Munera
- A Nabawi
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- A Nasr
- A Nawawi
- A Negida
- A Nesaratnam
- A Niragire
- A Nocito
- A Novak
- A Ogunyemi
- A Oluwagbemiga Lawal
- A Oosterkamp
- A Osama Elsebaaye
- A Osinowo
- A Osman Abdelaziz Elhendawy
- A P Arnaud
- A Popoola
- A Powell
- A Prabhudesai
- A R Mitul
- A Ragab Nayel
- A Ragab Soliman
- A Ramadan
- A Ramos-De La Medina
- A Rasendran
- A Rasendran
- A Rasendran
- A Rashid
- A Raslan
- A Riaz
- A Rotundo
- A Rslan
- A Rudzenskaite
- A S Mironescu
- A S North
- A Sabry
- A Sabry El-Hamouly
- A Sadek
- A Safwan Marey
- A Sakr
- A Salah Elsherbiny
- A Salleh
- A Samir
- A Sanad
- A Sayed
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- A Shabkah
- A Shah
- A Shalaby
- A Sheshe
- A Skardžiukaitė
- A Solaiman El-Ma'doul
- A Spina
- A Sreedharan
- A Sriram
- A Stephen
- A Strazdas
- A Szczap
- A Tade
- A Tammam
- A Tanase
- A Tanase
- A Tang
- A Tarek
- A Tarek Hafez
- A Thorell
- A Usaityte
- A Vega Carreiro De Freitas
- A Venâncio De Sousa
- A Vlachogiorgos
- A W Anwar
- A Watts
- A Williamson
- A Wilson
- A Zani
- A Zardab
- A Zeynel A Balkan
- A Zil-E-Ali
- Abid Bin Mahamood
- B Albeladi
- B Alghamdi
- B B Ozkan
- B B Ozkan
- B Cameron
- B F Hon Khi Chong
- B Frisk
- B Magdy
- B Mansour
- B Mijuskovic
- B Nighat
- B Odeyemi
- B Pereira
- B Pereira Silvestre
- B S Kumar
- B Sieda
- B Skelly
- B Thompson
- B Van Duren
- B Weber
- B Wolf
- B-V Martian
- C A Arroyo Basto
- C A Azmitia Mendizabal
- C Agalianos
- C Anthoulakis
- C Beaton
- C Bode
- C Boereboom
- C Bowman
- C C Goh
- C C L Szeto
- C C Ramã Rez Cabrera
- C Ceriani
- C Chandrakumar
- C Clifford
- C Currow
- C Dervenis
- C Diaz-Zorrilla
- C E Lopez
- C Fahy
- C Fairfield
- C Fairfield
- C Fermani
- C Gouldthorpe
- C Grossart
- C Hand
- C Hinojosa
- C Houlden
- C I Pérez Velásquez
- C J Mcintyre
- C Jenvey
- C Jones
- C Khatri
- C Koh
- C Lee
- C Leung Chong
- C Leung Chong
- C Leung Chong
- C Lopez-Arevalo
- C López
- C M Rees
- C Magee
- C Mangan
- C Mangan
- C Marinos
- C Mason
- C Milagros Herrera Puma
- C Morales
- C Morgan
- C Muller
- C Nawara
- C Neophytou
- C Normile
- C Normile
- C Nwokoro
- C Oliveira Felipe
- C Ou Yong
- C P García Torres
- C P Major
- C Raslan
- C S Wong
- C Sampson
- C Schoewe
- C Smith
- C Tedjaatmadja
- C Tolg
- C Venugopal
- C Vinícius Barroso de Lima
- C W Ho
- C Wredberg
- C Y Chen
- C Y Tan
- D A Amin Elsorogy
- D A Raptis
- D A Romani Pozo
- D A Soeselo
- D Alkhabbaz
- D Anandkumar
- D Anderson
- D Bowley
- D Brown
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- D Dabessa
- D Donoghue
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- D Duarte Cadogan
- D E Marroquín Rodríguez
- D Emadeldin
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- D M Cocker
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- D Roi
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- D Vinicius Dos Santos
- D Youssef
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- D-C Zachariades
- E Abdallah
- E Abington
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- E Ali Ahmed
- E Aljohani
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- E G Escobar
- E G Heywood
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- E M Harrison
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- E Macdermid
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- E Mamdouh
- E Marks
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- E N W Yeung
- E Niyirera
- E Nofal
- E P Refianti Sutanto
- E Panieri
- E Preckailaite
- E Rausa
- E Schadde
- E Snyder
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- E Y A Palkhi
- F A Asele
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- F Frade
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- F M Iqbal
- F N Rahmawati
- F Nada
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- F S Peck
- F Sauvat
- F Schmitt
- F Tale
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- F Y Lam
- F Zheng
- F-M Iordache
- G Azzie
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- G Dawnay
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- G Elena
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- M S J Wilson
- M S Weinstein
- M Saad
- M Sabry Ammar
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- M Saeed
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- M Zapata Ponze De Leon
- M Zidan
- M Zikry
- M Zuber
- N A Nik Abdullah
- N Abd El Hamid
- N Ahmed Attallah
- N Akeel
- N Badwi
- N Behar
- N Benons
- N Blencowe
- N Botto
- N Bugaev
- N D'aguzan
- N Elfouly
- N Elsayed
- N F Watson
- N Ghandora
- N Gobin
- N Gouvas
- N Green
- N Gyanchandani
- N Hall
- N Harrison
- N Herrera
- N J Hall
- N J Smart
- N J Wright
- N Kaselis
- N Limaye
- N M Urbina Rojas
- N Maple
- N Mcintyre
- N Mendez
- N Muralha
- N Ngayu
- N Nikoloudis
- N Osman
- N Panait
- N Pezelj
- N Phillips
- N R Kosai
- N Robertson
- N S Abebe
- N S Mitroudis
- N Sadig
- N Seyoum Abebe
- N Sishuba
- N Soltani
- N Soubhy El-Shahat
- N Starr
- N Yosri Elsayed Abdel-Wahab
- N Zanini
- O Abbo
- O Adesanya
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- O Al-Obaedi
- O Alahmady
- O Algohary
- O Azzam
- O Bouali
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- O Garaycochea
- O Javed
- O Javed
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- O Mohamed
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- O Nasher
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- O Oshodi
- O Osman
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- O Salah
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- O Sherief Abd El Hameed
- O Taiwo
- O Todd
- O Warren
- O Wiliams
- O Ziff
- P A Assouto
- P Acharya
- P Alves Bezerra Morais
- P C Munipalle
- P Capleton
- P Danelli
- P De Bono
- P Eduard
- P Harbord
- P Harrison
- P Holton
- P J Lim
- P Jackson
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- P Patel
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- P Singh
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- P Stassen
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- P Sutton
- P Thomson
- P Ugalde
- P Weber
- P Weber
- P Witherspoon
- P-O Lundgren
- Q Alimi
- Q Alimi
- R Adams
- R Allott
- R Alvarado Jaramillo
- R Alyami
- R Alyami
- R Amandito
- R Anderson
- R Araujo
- R Ardley
- R Balmaceda
- R Barrionuevo Ojeda
- R Beyene
- R Blundell
- R Bowe
- R Bugeja
- R Cahill
- R Camacho
- R Chenn
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- R Coasaca Huaraya
- R Coomber
- R D Obute
- R D S Omara
- R D'cruz
- R Darío Arias Pacheco
- R Davenport
- R Dean
- R Elmelegy
- R F Staerkle
- R Faccincani
- R Fakher
- R George
- R Gilbert
- R Goh Ern Tze
- R Gratton
- R Guevara
- R Harrison
- R K M Jawad Al-Hasani
- R Kamil
- R Karlo
- R Kennedy
- R Kerley
- R King
- R Lages Simoes
- R Lawther
- R Lilford
- R M H Balila
- R Macchiavello
- R Mcdonald
- R Mcintosh
- R Mcintyre
- R Melo
- R Moore
- R Morton
- R Osuoji
- R Oumer
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- R Rajan
- R Rakauskas
- R Riauka
- R Rivas
- R Rodríguez-Uría
- R Sakr
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- R Schmid
- R Shah
- R Shaker
- R Shaker
- R Slade
- R Soley
- R Som
- R Spence
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- R Tyler
- R Villa
- R W Gilbert
- R Zilinskiene
- R-M Bratu
- S A Alnuqaydan
- S A Durand
- S Abd Elmageed Barakat
- S Abdelghany
- S Abdoun Ishag Idris
- S Ahlqvist
- S Al Awwad
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- S Anderson Khouri Ferreira
- S Antar
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- S Binna Kim
- S Bokhari
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- S Braungart
- S Breitenstein
- S Chhabra
- S Chidambaram
- S Chiu
- S Chung
- S Corro-Diaz Gonzalez
- S Cucumazzo
- S Das
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- S Dias
- S Dindyal
- S Doughan
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- S Elsobky
- S Estupinian
- S F Ashraf
- S Fergusson
- S G Gosling
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- S Ghanem
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- S Gosling
- S Hafiz
- S Haines
- S Hallam
- S Hassan
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- S J Chapman
- S J Lim
- S Juciute
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- S K Pitt
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- S Khan
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- S M Contreras Mérida
- S M Lakhani
- S M Sundstrom
- S Magdy Ahmed
- S Mahdi
- S Man Yeng Chiu
- S Mcaleer
- S Mehrez
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- S Mitrasinovic
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- S Nadkarni
- S Ng
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- S Ramzi
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- S Rayne
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- S Roy
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- S Samy
- S Sani Ali
- S Sarsik
- S Sarwary
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- S Shaikh
- S Shehata
- S Sheth
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- S Sierra
- S Singh
- S Sinha
- S Sivaganesh
- S Stock
- S Tabiri
- S Talukder
- S Talukder
- S Tewari
- S Tharmalingam
- S Tou
- S V Kinnera
- S Vivekanantham
- S Ward
- S Wondimu
- S Zegarra
- S Zeidan
- S-H Kim
- S-P Hosein
- T A M Malik
- T Akeem Lawal
- T Alzayat
- T Arulampalam
- T B Wold
- T Barker
- T Boyce
- T Brogden
- T Chun
- T Clark
- T E Glover
- T Ebogo Ngwa
- T F Jones
- T Falconer Hall
- T Farooq
- T Fautz
- T Fernandes Giuriato
- T Fozard
- T Fozard
- T Khan
- T Kumar
- T M Drake
- T Mak
- T Muhammad Yaseen
- T Naqvi
- T Newton
- T Nouh
- T O'Connor
- T Pezas
- T Poskus
- T Razek B Marinkovic
- T S Hettiarachchi
- T Sherman
- T Stasinou
- T Urbonas
- T W Tilston
- T White
- T Xerri
- T Yaseen
- U Alamoudi
- U Gunnarsson
- U Gustafsson
- U Hantour
- U Karabacak
- U Walsh
- V Ambrozeviciute
- V Beisa
- V D Palomino Castillo
- V Despotidis
- V Gadhvi
- V Graffeille
- V Graffieille
- V Grassi
- V J P Nsengimana
- V Jennings
- V Jotautas
- V K Proctor
- V Kong
- V M Quintero Riaza
- V Parent
- V Patel
- V Punja
- V Sallinen
- V Shatkar
- V Summerour
- V Thanusan
- W Adham
- W Anwer
- W Beasley
- W C Ho
- W C Soon
- W Chachulski
- W Forno
- W Guo
- W Hawkins
- W Ho
- W Hutch
- W J Lossius
- W L Messa Aguilar
- W L Messa Aguilar
- W Milligan
- W Milligan
- W Pino
- W S Li
- W S M Kithsiri Janakantha Senanayake
- Y Abd El Salam
- Y Abd Elrasoul
- Y Abd-Elrasoul
- Y Aigrain
- Y Cengiz
- Y El Shoura
- Y Elfouly
- Y Hegazy
- Y Ibrahim
- Y Imorou Souaibou
- Y Macchitella
- Y N Neo
- Y P Mogan
- Y Rajjoub
- Y Reddy
- Y Salama
- Y Sinha
- Z Chan
- Z Dambrauskas
- Z Hassan
- Z Iftikhar
- Z Jaffry
- Z Mikwar
- Z Oof
- Z Urniezius
- Z Zhang
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2016
- Field of study
Background: Surgical mortality data are collected routinely in high-income countries, yet virtually no low- or middle-income countries have outcome surveillance in place. The aim was prospectively to collect worldwide mortality data following emergency abdominal surgery, comparing findings across countries with a low, middle or high Human Development Index (HDI).
Methods: This was a prospective, multicentre, cohort study. Self-selected hospitals performing emergency surgery submitted prespecified data for consecutive patients from at least one 2-week interval during July to December 2014. Postoperative mortality was analysed by hierarchical multivariable logistic regression.
Results: Data were obtained for 10 745 patients from 357 centres in 58 countries; 6538 were from high-, 2889 from middle- and 1318 from low-HDI settings. The overall mortality rate was 1⋅6 per cent at 24 h (high 1⋅1 per cent, middle 1⋅9 per cent, low 3⋅4 per cent; P < 0⋅001), increasing to 5⋅4 per cent by 30 days (high 4⋅5 per cent, middle 6⋅0 per cent, low 8⋅6 per cent; P < 0⋅001). Of the 578 patients who died, 404 (69⋅9 per cent) did so between 24 h and 30 days following surgery (high 74⋅2 per cent, middle 68⋅8 per cent, low 60⋅5 per cent). After adjustment, 30-day mortality remained higher in middle-income (odds ratio (OR) 2⋅78, 95 per cent c.i. 1⋅84 to 4⋅20) and low-income (OR 2⋅97, 1⋅84 to 4⋅81) countries. Surgical safety checklist use was less frequent in low- and middle-income countries, but when used was associated with reduced mortality at 30 days.
Conclusion: Mortality is three times higher in low- compared with high-HDI countries even when adjusted for prognostic factors. Patient safety factors may have an important role. Registration number: NCT02179112 (http://www.clinicaltrials.gov)
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
- Author
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- Aaniana K
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- Abaliksta T
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- Abbasy J
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- Abbo O
- Abbott T
- Abbouch M
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
- Abdallah E
- Abdel-Aty A
- Abdel-Hameed N
- Abdel-Kader Sm
- Abdel-Wahab Nye
- Abdelaal A
- Abdelaty M
- Abdelazeam Ar
- Abdelazim G
- Abdelaziz Ma
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- Abdelfatah A
- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelhady S
- Abdelhamed R
- Abdelhamid A
- Abdelhaq A
- Abdelkader M
- Abdelkader M
- Abdelkader O
- Abdelkareem A
- Abdelkhalek M
- Abdelmageed E
- Abdelmotaleb I
- Abdelraheim M
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- Abdelshafy M
- Abdelshakour M
- Abdrabou Ak
- Abdul-Latif S
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- Abdulgawad M
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- Chen Cy
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- Chidambaram S
- Chiesa D
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- Chowdhury A
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- Clegg-Lamptey Jn
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- De La Medina AR
- de Leó
- De Leon MZP
- De Leon MZP
- de Lima CVB
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- Deichsel F
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- Delgado Msftl
- Dell A
- Dempster E
- Denewar A
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- Devadasar Gh
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- Diaconescu B
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- Djivoh F
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- Donoghue D
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- Duhoranenayo D
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- El Salam YA
- El Sayed GS
- El Sayed IM
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- El-Ma&apos
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- El-Sagheer N
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- Elfiky M
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- Elgendy Fi
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- Elkelany A
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- Elkorashy Am
- Ellison Q
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- Elnemr Ae
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- Elsherif Fa
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- Elzowawi F
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- Escobar Eg.
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- Farinella E
- Farmakis K
- Farooq T
- Farouk Sam
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy Am
- Fattah Aa
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe Co
- Fergany A
- Fergusson Sj
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- Fermani C
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- Fitzgerald Je
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- Fowler Aj
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- Frade F
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- Fujii F
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- Kyrou G
- Kyziridis D
- Ló
- L&apos
- La Brocca A
- la Medina AR
- la Medina AR
- la Medina AR
- Labib P
- Ladukas A
- Lafferty K
- Lagunavicius K
- Lai Ac
- Lakhani Sm
- Lakshmi Hn
- Lam Fy
- Lam Jcy
- Lam Wh
- Lamanna Gl
- Lanau Miv
- Lando J
- Landolfo G
- Landolfo G
- Lap G
- Lapitan Mc
- Lapitan Mc
- Larsen Jw
- Lasek A
- Lasheen A
- Lasheen Kt
- Latif A
- Laufer Lav
- Laugzemys E
- Laugzemys E
- Laurie K
- Lauzikas G
- Law Jh
- Lawal A
- Lawal Ao
- Lawal T
- Lawal Ta
- Lawani I
- Lawther R
- Lazzari G
- Lazzari V
- Leal A
- Leal M
- Lecompte Jf
- Lee C
- Lee Ex
- Lee F
- Lee K
- Lee Kc
- Lee Ky
- Lee Tsb
- Lemaire Sb
- Leone N
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- Leppä
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- Leroux J
- Leung Kw
- Leung Mf
- Leusink A
- Lewis J
- Li Ws
- Licari L
- Lieske B
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- Liew I
- Liew I
- Lilford R
- Lilford R
- Lilford Rj
- Lim G
- Lim H
- Lim J
- Lim Pj
- Lim Sj
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- Lim Sy
- Limache S
- Limaye N
- Limoges B
- Lintin L
- Lipnickas V
- Litvin A
- Liu Q
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- Livesey A
- Livingston M
- Ljuhar D
- Lo Conte A
- Loaloa Mr
- Lockey J
- Lohse Has
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- Loizides S
- Lokman Maa
- Longstaff L
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- Lopez M
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- Lorenzon L
- Lossius Wj
- Loughran D
- Low X
- Luc Ar
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- Luck J
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- Luglio G
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- Lundgren Po
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- Lytras D
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- Má
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- Ma J
- Mabitsela Me
- Mabrouk M
- Macchiavello R
- Macchitella Y
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- Macdermid E
- Macdonald A
- Macdonald E
- Macdonald L
- Maceviciute K
- Macfarlane A
- Machaca M
- Maciejec L
- Madiba T
- Madkor Mh
- Maffioli A
- Maffioli A
- Magdy A
- Magdy B
- Magdy E
- Magdy H
- Magdy M
- Magdy S
- Magee C
- Maghrabi A
- Maghrabi Aa
- Magri D
- Mahamood Ab
- Mahanty S
- Maharaj G
- Mahdi A
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- Maher Me
- Mahmoud B
- Mahmoud H
- Mahmoud M
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- Mahmoud Mi
- Mahmoud S
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- Maistry N
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- Makinde M
- Makupe A
- Malavenda M
- Malik K
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- Mamdouh E
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- Manatakis Dk
- Manfreda S
- Mangan C
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- Mangiapane M
- Manipal Ce
- Maniscalco A
- Mann T
- Mannu Gs
- Manriquez-Reyes M
- Mansor Ey
- Mansour B
- Mansour S
- Mansuri A
- Mao P
- Mapasse D
- Maple N
- Maraie N
- Marey A
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- Margaritis M
- Mariani A
- Marinkovic B
- Marinos C
- Marks E
- Marples L
- Marret Jb
- Marshall Dc
- Martian Bv
- Martin A
- Mas R
- Mason C
- Mata Lps
- Matheu A
- Mathew Sw
- Matos-Puig R
- Matta Jjh
- Mattar O
- Matter Sm
- Mauro L
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- Mazrimas P
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- McGarvie S
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- McMorran D
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- Mendoza I
- Menegussi J
- Mensah E
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- Mentula P
- Meqbil J
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- Merlini D
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- Merlo Ms
- Mesbah N
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- Mihaljevic Al
- Mihanovic J
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- Mijuskovic B
- Mikalauskas S
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- Mikuckyte D
- Mikwar Z
- Milligan W
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- Mingrone P
- Minguez G
- Minocha A
- Minocha A
- Miranda C
- Mircea H
- Mirghani D
- Mironescu A
- Mironescu A
- Mironescu As
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- Mirza A
- Mirza S
- Mistry A
- Mitrasinovic S
- Mitroudi M
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- Mittal A
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- Miyasato Hs
- Mizzi C
- Mizzi S
- Mlotshwa M
- Moaty M
- Mochet S
- Modolo Mm
- Modolo Mm
- Modolo Mm
- Moe Tt
- Mogan Yp
- Moghazy Me
- Mohamed A
- Mohamed A
- Mohamed Am
- Mohamed Ar
- Mohamed B
- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed Ma
- Mohamed Maeh
- Mohamed Mm
- Mohamed O
- Mohamed Sr
- Mohameden A
- Mohammad A
- Mohammad A
- Mohammed A
- Mohammed A
- Mohammed Ae
- Mohammed Ar
- Mohammed H
- Mohammed Mm
- Mohammed Mmh
- Mohammed S
- Mohan H
- Mohan M
- Mohan M
- Mok Yt
- Mokhtar A
- Molina G
- Mollo Mc
- Monaghan E
- Monaghan E
- Monrad-Hansen Pw
- Montejo Msg
- Monteleone M
- Monteleone M
- Montes I
- Montes I
- Montrimaite M
- Montrimaite M
- Moodley Y
- Moore R
- Moore R
- Mora Jjv
- Morais Pab
- Morales C
- Moran Aer
- Morandi E
- Moreira G
- Moreno Sc
- Morgan C
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- Morshedy Em
- Morsi A
- Morsi M
- Morton D
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- Morton R
- Mosad A
- Mosalum O
- Mostafa Ha
- Mostafa M
- Mostafa M
- Mousa M
- Moussa O
- Moustafa A
- Mouttalib S
- Mowafy B
- Mphatsoe Am
- Mshelbwala P
- Msiska N
- Msosa V
- Msosa V
- Muddebihal U
- Mukin Adf
- Muktar U
- Mukuzunga C
- Muller C
- Muller C
- Munera A
- Munhoz Mm
- Munipalle Pc
- Muntean L
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- Muralha N
- Murphy J
- Murray A
- Murutoglu B
- Musa Aek
- Musleh A
- Musowoya J
- Mussad A
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- Musyoka Ck
- Mutabazi Az
- Mutabazi Az
- Mutlu D
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- Muzio E
- Myers J
- Mykoniatis I
- Næ
- Nabawi A
- Nada F
- Nadeem N
- Nadkarni S
- Nagy Gs
- Nahar Sn
- Nair H
- Nanthakumaran S
- Napolitano L
- Napolitano L
- Naqvi Sa
- Naqvi T
- Naranjo Aristizã
- Narayanan R
- Narayanan R
- Narvestad Jk
- Nashaat A
- Nashat M
- Nasher O
- Nashidengo P
- Nasir A
- Nasir Aa
- Nasr A
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- Nassif D
- Nastri G
- Natalie H
- Nataraja R
- Natili A
- Navarro A
- Nawara C
- Nawawi A
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- Nayel Ar
- Nazir M
- Ndajiwo A
- Ndajiwo A
- Ndegwa W
- Ndlovu Sr
- Ndwambi P
- Ne&apos
- Negida A
- Negoi I
- Nel D
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- Neo Yn
- Neo Yt
- Neophytou C
- Nepogodiev D
- Nepogodiev D
- Nepogodiev D
- Nepogodiev D
- Nesaratnam A
- Nessa A
- Nestorovic M
- Nevieraite V
- Newton T
- Ng S
- Ng Yk
- Ng Zh
- Ngayu N
- Ngwa Te
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- Nicholson L
- Nighat B
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- Nikberg M
- Nikoloudis N
- Nikoloudis N
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- Niranjan N
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- Niyirera E
- Njokanma I
- Nnajiuba H
- Nocito A
- Nocito A
- Nofal E
- Noor F
- Normile C
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- North As
- Notarnicola M
- Notarnicola M
- Nouh T
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- Noukpozounkou B
- Novak A
- Nowers J
- Nsengimana Vjp
- Nsengiyumva C
- Ntirenganya F
- Nur&apos
- Nurqistan Hd
- Nwabuoku E
- Nwinee V
- Nwokoro C
- Nyberg J
- Nymo L
- O&apos
- O&apos
- O&apos
- O&apos
- O&apos
- O&apos
- Obute Rd
- Occhionorelli S
- Odeyemi B
- Odeyemi B
- Odutola O
- Ogunsua O
- Ogunyemi A
- Oh J
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- Ohene-Yeboah M
- Ojeda Rrb
- Okenabirhie O
- Olajide To
- Olaolorun A
- Olivier J
- Olori S
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- Oludara M
- Oludara M
- Olugbemi M
- Omar Aa
- Omar Me
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- Omara S
- Omer Oa
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- Onuoha C
- Oosterkamp A
- Opoku-Agyeman R
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- Ortega-Vazquez I
- Ortiz N
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- Oshati O
- Oshodi O
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- Oswald D
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- Othman M
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- Owen C
- Owusu F
- Owusu F
- Ozben V
- Ozkan Bb
- Ozkan Bb
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- Pabla G
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- Padmore G
- Pagano G
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- Pagnozzi J
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- Palma Af
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- Papailia A
- Papandrea M
- Papaskarlatos Ia
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- Parreno-Sacdalan Md
- Parseliunas A
- Parthiban S
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- Pasquali S
- Pastora J
- Pata D
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- Pata F
- Pata F
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- Pata F
- Pata F
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- Patoulias I
- Paul M
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- Pesenti G
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- Pezas T
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- Picardo A
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- Pino W
- Pitt Sk
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- Pozo Dar
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- Pranevicius R
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- Preckailaite E
- Primavesi F
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- Proctor Vk
- Pronin S
- Prudhomme T
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- Puma Cmh
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- Puttick M
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- Raza A
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- Razmdjou S
- Razuri C
- Razzaque J
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- Redota Map
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- Runigamugabo E
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- Sabour Fa
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- Sahel S
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- Salama M
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- Salleh A
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- Sallinen V
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- Salma M
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- Salma U
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- Sam Zh
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- Samaniego Cs
- Samaraweera Di
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- Sammarco G
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- Sampson C
- Samson G
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- Sanz S
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- Saravia F
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- Sasia D
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- Scalabre A
- Scalabre A
- Schadde E
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- Schiavone R
- Schivo D
- Schmid R
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- Schultz Jk
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- Semeda N
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- Senanayake Kj
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- Senanayake W
- Septiem Jg
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- Setiawan J
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- Sfougaris D
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- Shah A
- Shah J
- Shah R
- Shaharuddin S
- Shahbaz Ar
- Shaheen A
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- Shahzad N
- Shaikh N
- Shaikh S
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- Shalabi A
- Shalaby A
- Shalaby M
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- Shamasneh A
- Shamsedine Aw
- Shamsi G
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- Shariffuddin Am
- Sharma A
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- Shatkar V
- Shaw Ca
- Shawki M
- Shawki M
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- Shawqi M
- Sheehan J
- Shehata S
- Sherif Ma
- Sherman T
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- Sheshe A
- Sheta A
- Sheth S
- Shillito S
- Shimy G
- Shiwani H
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- Sholadoye T
- Shrimanker N
- Shu S
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- Shu S
- Shubianok M
- Shukla J
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- Sieda B
- Sierra S
- Sierra S
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- Siguantay M
- Sigurdadottir J
- Sii Ssy
- Sila Gcm
- Sila Gm
- Sila Gm
- Sileri P
- Silvani P
- Silvestri V
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- Simutis G
- Singh P
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- Sinha Y
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- Sivaganesh S
- Skardž
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- Slapelyte E
- Sleem As
- Sleem M
- Smart N
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- Smedley A
- Smith C
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- Smith D
- Snaith Ac
- Snyder E
- Sobnach S
- Sodde P
- Soeselo Da
- Sokratous A
- Solaini L
- Soldevila-Verdeguer C
- Soley R
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- Soliman A
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- Soliman N
- Soliman Na
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- Solis Laz
- Sollazzo V
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- Souaibou Yi
- Souaibou Yi
- Soulou V
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- Spence R
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- Sproule L
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- Srinivasan R
- Sriram A
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- Steccanella F
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- Suarez A
- Suarez Aab
- Subocius A
- Suleiman Si
- Summerour V
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- Sundstrom Sm
- Suresh S
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- Sykes M
- Szczap A
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- Taddei A
- Tade A
- Tafazal H
- Taha Ems
- Tahboub H
- Taher Aa
- Taher M
- Taher Mm
- Taieb C
- Taiwo A
- Taiwo O
- Taiwo O
- Talaat M
- Tale F
- Tale L
- Talukder S
- Talukder S
- Talving P
- Talving P
- Tammam A
- Tan C
- Tan Cl
- Tan Cy
- Tan Jj
- Tan Jk
- Tan Ksk
- Tan Rck
- Tan Yk
- Tan Yw
- Tanase A
- Tanase A
- Tang A
- Tang L
- Tani Si
- Tansoker I
- Tarek A
- Tarek A
- Tarek D
- Targa S
- Tariq S
- Tata Md
- Tatagiba Ls
- Tawfik Ba
- Tawfik G
- Tawfik G
- Taylor F
- Teasdale E
- Teasdale E
- Teasdale E
- Teasdale E
- Tedeschi U
- Tedjaatmadja C
- Telfah Mm
- Tembo T
- Temoche E
- Tennakoon A
- Teo Sy
- Ter Ez
- Tessera G
- Teufelberger G
- Tew Yy
- Tew Yy
- Tewari S
- Th&apos
- Thabet W
- Thalgaspitiya Spb
- Tham Jc
- Thanusan V
- Tharmalingam S
- Theodosopoulos T
- Thollot A
- Thomas E
- Thompson B
- Thomson P
- Thorarinsdottir H
- Thorarinsdottir H
- Thorell A
- Thorell A
- Thorsen K
- Thurairaja R
- Ticona Wa
- Tierney G
- Tilston Tw
- Timothy Ok
- Ting Jrs
- To K
- To K
- Todd O
- Toeema Ag
- Tolba H
- Tolg C
- Tolonen M
- Tolotra Tec
- Tori Sa
- Torrance Hd
- Torrance Hd
- Torres Cpg
- Torres Sg
- Toto Ö
- Tou S
- Townsend D
- Tracy J
- Trompetto M
- Tselos A
- Tshisola Sk
- Tugnoli G
- Tugnoli G
- Tun Ak
- Tun M
- Tun M
- Turati L
- Turati L
- Turkustani S
- Turner M
- Tutino R
- Tverskis Z
- Tyler R
- Tyler R
- Tze Rge
- Tze Rge
- Tzikos G
- Uš
- Ubhi Hk
- Ubiali P
- Ugalde P
- Ukwenya Y
- Uluş
- Ulusahin M
- Upadhyaya V
- Upchurch E
- Urbanavicius L
- Urbonas T
- Urbonas T
- Urniež
- Urniezius Z
- Urquizu Mc
- Usaityte A
- Utter M
- Uzabumwana N
- Vaicius A
- Valcarcel-Saldañ
- Valioulis I
- Van Der Naald N
- Van Duren B
- Van Niekerk M
- Van Straten S
- Varcada M
- Vargas M
- Varkalys K
- Vartanoglu T
- Vartic M
- Vartic M
- Vasquez G
- Vasquez I
- Veen T
- Vega Gmm
- Vega Gmm
- Velá
- Velá
- Velasquez R
- Vella-Baldacchino M
- Venclauskas L
- Vendramin E
- Venskutonis D
- Venskutonis D
- Venskutonis D
- Venskutonis D
- Venugopal C
- Verbeek A
- Vergara Alc
- Verjee A
- Vermaas M
- Veronese E
- Viš
- Vianna P
- Vicario E
- Vico Td
- Vida Lc
- Vida Lc
- Vilč
- Villa R
- Villalobos S
- Villegas Mi
- Vimalachandran D
- Vincent J
- Violi P
- Vivekanantham S
- Vlachogiorgos A
- Voulgaris E
- Vth Le
- Wael N
- Wagener M
- Wakefield R
- Walę
- Waleed H
- Walker M
- Walker N
- Walls L
- Walsh M
- Walsh U
- Waqar M
- Ward Ae
- Ward S
- Warda M
- Warren O
- Warren O
- Warwick Am
- Waterman A
- Watson Nf
- Watts A
- Weber B
- Weber P
- Weber P
- Weinstein Ms
- Werder G
- Wheeler J
- Whewell H
- Whitaker J
- White R
- White T
- Whitehurst K
- Wiborg J
- Widiastini Ta
- Widmer Lw
- Wijayarathna Ls
- Wild Jrl
- Williams E
- Williams G
- Williams O
- Williams O
- Williamson A
- Wilson A
- Wilson L
- Wilson M
- Wilson M
- Wilson Ms
- Wilson Msj
- Wimalge Pmsn
- Winstanley J
- Witherspoon P
- Wogensen F
- Wogensen F
- Wogensen F
- Woin E
- Wold Tb
- Wolf B
- Wolf B
- Wondimu S
- Wondoh P
- Wondoh P
- Wong Cs
- Wong Cy
- Wong F
- Wong Hy
- Wood G
- Woodward H
- Worku M
- Worku M
- Worku T
- Wredberg C
- Wright N
- Wright Nj
- Xerri T
- Xerri T
- Yahaya Mt
- Yakubu M
- Yallop L
- Yam Sy
- Yang J
- Yap S
- Yaseen T
- Yaseen Tm
- Yau Jd
- Yavuz Ma
- Ye J
- Yeang Lj
- Yee J
- Yeo Ls
- Yeung En
- Yeung Mha
- Yifieyeh A
- Yildirim R
- Yip C
- Yip Sbs
- Ymeri S
- Yoganathan P
- Yolcu S
- Yong Co
- Yong Gl
- Younis A
- Youssef D
- Youssef H
- Youssef M
- Youssif Jh
- Yuksek Ma
- Yusufali T
- Zaa&apos
- Zachariades Dc
- Zadoroznas A
- Zahran D
- Zakaria E
- Zakaria M
- Zakaria Y
- Zaki A
- Zakir M
- Zalabia Mf
- Zamarin K
- Zammit S
- Zampitis N
- Zani A
- Zani A
- Zani A
- Zanini N
- Zanini N
- Zapata F
- Zarb C
- Zardab A
- Zegarra S
- Zeidan S
- Zerihun Ab
- Zhang Z
- Zheng F
- Zidan H
- Zidan H
- Zidan M
- Zielinski M
- Ziff O
- Zikry M
- Zil-E-Ali A
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskiene R
- Zimmermann Ef
- Zohair A
- Zorrilla Cd
- Zuber M
- Zuber M
- Zuk G
- Zulkifli A
- Zumbü
- Publication venue
- 'Wiley'
- Publication date
- 27/11/2018
- Field of study
Background
End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection.
Methods
This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associated with colostomy formation versus primary anastomosis were explored using a multilevel, multivariable logistic regression model.
Results
In total, 1635 patients from 242 hospitals in 57 countries undergoing left-sided colorectal resection were included: 113 (6·9 per cent) from low-HDI, 254 (15·5 per cent) from middle-HDI and 1268 (77·6 per cent) from high-HDI countries. There was a higher proportion of patients with perforated disease (57·5, 40·9 and 35·4 per cent; P < 0·001) and subsequent use of end colostomy (52·2, 24·8 and 18·9 per cent; P < 0·001) in low- compared with middle- and high-HDI settings. The association with colostomy use in low-HDI settings persisted (odds ratio (OR) 3·20, 95 per cent c.i. 1·35 to 7·57; P = 0·008) after risk adjustment for malignant disease (OR 2·34, 1·65 to 3·32; P < 0·001), emergency surgery (OR 4·08, 2·73 to 6·10; P < 0·001), time to operation at least 48 h (OR 1·99, 1·28 to 3·09; P = 0·002) and disease perforation (OR 4·00, 2·81 to 5·69; P < 0·001).
Conclusion
Global differences existed in the proportion of patients receiving end stomas after left-sided colorectal resection based on income, which went beyond case mix alone
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Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation
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- Adjei Andrew A.
- Adolfson Jan
- Al Olama Ali Amin
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- Auvinen Anssi
- Barros-Silva Joao
- Batra Jyotsna
- Benlloch Sara
- Berg Christine
- Berndt Sonja I.
- Biritwum Richard B.
- Blot William J.
- Brenner Hermann
- Broms Michael
- Brown Paul
- Campa Daniele
- Cannon-Albright Lisa
- Carpten John
- Casey Graham
- Cavalli-Bjoerkman Carin
- Chokkalingam Anand P.
- Christova Svetlana
- Chu Lisa
- Clements Judith A.
- Collins Angus
- Conti David V.
- Cook Margaret
- Cook Michael B.
- Cox Angela
- Crawford E. David
- Cybulski Cezary
- Dadaev Tokhir
- Davis Michael
- Dieffenbach Aida K.
- Dikov Tihomir
- Diver W. Ryan
- Donovan Jenny L.
- Easton Douglas
- Eckert Allison
- Eeles Rosalind A.
- Fisher Cyril
- Fitzgerald Liesel M.
- Freedman Matthew L.
- Gapstur Susan M.
- Gaziano J. Michael
- George Anne
- Giles Graham G.
- Giovannucci Edward
- Goodman Phyllis J.
- Govindasami Koveela
- Gronberg Henrik
- Gusev Alexander
- Gustafsson Sven
- Guy Michelle
- Haiman Christopher A.
- Haley James
- Hamdy Freddie C.
- Hazel Steve
- Heathcote Peter
- Henderson Brian E.
- Hennis Anslem J. M.
- Henrique Rui
- Herkommer Kathleen
- Hoover Robert
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- Hsing Ann W.
- Hunter David J.
- Ingles Sue A.
- Isaacs William B.
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- Johansson Jan-Erik
- Johansson Mattias
- John Esther M.
- Kachakova Darina
- Kaggwa Sam
- Kaneva Radka
- Karlsson Ami
- Kedda Mary-Anne
- Kerr Kris
- Key Tim J.
- Khaw Kay-Tee
- Kibel Adam S.
- Kichaev Gleb
- Kierzek Andrzej
- Kittles Rick A.
- Klarskov Peter
- Klein Eric A.
- Kluzniak Wojciech
- Kote-Jarai ZSofia
- Kraft Peter
- Kujala Paula
- Lane Athene
- Le Marchand Loic
- Leongamornlert Daniel
- Leske M. Cristina
- Li Fugen
- Lin Hui-Yi
- Lindström Sara
- Livni Naomi
- Long Henry W.
- Lophatananon Artitaya
- Lubiski Jan
- Luedeke Manuel
- Maeaettaenen Liisa
- Maia Sofia
- Maier Christiane
- Malone Greg
- Marsden Gemma
- McDonnell Shannon K.
- Michael Agnieszka
- Mitev Vanio
- Mitkova Atanaska
- Morgan Angela
- Muir Kenneth
- Murphy Adam B.
- Murtola Teemu
- Navarro Carmen
- Neal David E.
- Nemesure Barbara
- Neslund-Dudas Christine
- Nielsen Sune F.
- Niwa Shelley
- Nordestgaard Børge G.
- Omara Tracy
- Overvad Kim
- Pandha Hardev
- Park Hyun
- Park Jong Y.
- Pasaniuc Bogdan
- Pashayan Nora
- Paulo Paula
- Pedersen John
- Pettaway Curtis A.
- Pharoah Paul
- Pinto Pedro
- Pomerantz Mark
- Popov Elenko
- Pow-Sang Julio
- Price Alkes L.
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- Rincon Maria
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- Roder Andreas
- Rybicki Benjamin A.
- Santos Joana
- Saunders Edward J.
- Saunders Pamela
- Sawyer Emma J.
- Schaid Daniel J.
- Schleutker Johanna
- Schumacher Frederick R.
- Sellers Thomas A.
- Shi Huwenbo
- Siddiq Afshan
- Signorello Lisa B.
- Slavov Chavdar
- Southey Melissa C.
- Spurdle Amanda
- Srinivasan Srilakshmi
- Stanford Janet L.
- Stattin Paer
- Stegmaier Christa
- Stevens Victoria L.
- Stram Daniel O.
- Strom Sara S.
- Taari Kimmo
- Tammela Teuvo L. J.
- Tay Evelyn
- Teerlink Craig
- Teixeira Manuel R.
- Tettey Yao
- Thibodeau Stephen N.
- Tillmans Lori
- Travis Ruth C.
- Trichopoulos Dimitrios
- Truelove Ann
- Trynka Gosia
- Turner Megan
- Tymrakiewicz Malgorzata
- Vineis Paolo
- Vlahova Aleksandrina
- Vogel Walther
- Wahlfors Tiina
- Wallinder Hans
- Wang Liang
- Weischer Maren
- Wiklund Fredrik
- Wilkinson Rosemary
- Witte John S.
- Wokolorczyk Dominika
- Wood Glenn
- Wu Huihai
- Wu Suh-Yuh
- Yeadon Trina
- Yeager Meredith
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- 'Springer Science and Business Media LLC'
- Publication date
- 02/05/2016
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Although genome-wide association studies have identified over 100 risk loci that explain ∼33% of familial risk for prostate cancer (PrCa), their functional effects on risk remain largely unknown. Here we use genotype data from 59,089 men of European and African American ancestries combined with cell-type-specific epigenetic data to build a genomic atlas of single-nucleotide polymorphism (SNP) heritability in PrCa. We find significant differences in heritability between variants in prostate-relevant epigenetic marks defined in normal versus tumour tissue as well as between tissue and cell lines. The majority of SNP heritability lies in regions marked by H3k27 acetylation in prostate adenoc7arcinoma cell line (LNCaP) or by DNaseI hypersensitive sites in cancer cell lines. We find a high degree of similarity between European and African American ancestries suggesting a similar genetic architecture from common variation underlying PrCa risk. Our findings showcase the power of integrating functional annotation with genetic data to understand the genetic basis of PrCa
Interleukin-6 level is a powerful predictor of risk for acute myeloid leukemia (AML) among Iraqi patients: A pilot study
- Publication venue
- Universidad Tecnica de Manabi
- Publication date
- 21/07/2022
- Field of study
Background: Several studies demonstrate the existence of cytokine dysregulation in patients with acute myeloid leukemia (AML), which may be associated with pathogenesis, disease progression, and patient survival. The aim of this study was to evaluate the association of IL-6 levels and the risk of AML among Iraqi patients. Methods: A case-control study was carried out to analyze IL-6 levels in the serum of 60 patients with AML and a healthy control group. In this study, AML patients were divided into two groups: 30 AML before receiving treatment and 30 AML after receiving treatment. A variety of biochemical and anthropometric measurements, such as sex and age, BMI, serum IL-6, ALT, AST, urea, and creatinine levels, were examined in this study. Results: With regard to the patient group, the BMI, RBC, WBC, Hb, Lymphocytes, neutrophils, platelets, serum ALT, AST, urea, and creatinine levels revealed a significant difference compared with the control group.  
Plant growth, yield and quality of potato crop in relation to potassium fertilization
- Author
- Publication venue
- 'MDPI AG'
- Publication date
- 01/01/2021
- Field of study
The present work evaluated the effect of soil (S) and foliage (F) applied potassium on the growth, yield, and quality of potato plants. Potassium was added in soil at the recommended rate for all the treatments combining mineral fertilizers with K-feldspar and biofertilizers, while foliar spraying included the application of potassium citrate (PC), potassium silicate (PS), and monopotassium phosphate (MP). The obtained results showed that plant height was highest following treatment with 100% mineral potassium fertilizer under the foliar application of MP, while the content of P, K, and total carbohydrates in leaves also increased with the same fertilization treatment. On the other hand, the highest values for number of stems and fresh and dry weight per plant, as well as the highest nitrogen content in leaves, were obtained after the addition of mineral potassium fertilizer and the foliar spraying of PC, regardless of the growing season. Yield parameters were positively affected by the combination of mineral potassium fertilizers (100% or 80% K2SO4 + 20% K-feldspar + biofertilizer) and the foliar spraying of MP, while the total nitrogen, protein, amino acids, potassium, phosphorus, and starch content of tubers were positively affected by the same mineral fertilizer treatments combined with foliar spraying of MP or CP. In conclusion, the application of mineral potassium fertilizer with foliar spraying of MP or CP increased most of the plant growth-and tuber chemical composition-related parameters. These results highlight the importance of potassium fertilizer regimes for achieving high tuber yields and improving the quality of tubers in a sustainable and cost-effective manner. © 2021 by the authors. Licensee MDPI, Basel, Switzerland
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