6 research outputs found

    Glycosidase inhibition: assessing mimicry of the transition state

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    A review of the progress made in tackling glycosidase inhibition, which has widespread application in a number of diseases, in particular by examining those inhibitors that may mimic the transition state

    Binding Energy, Specificity, and Enzymic Catalysis: The Circe Effect

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    Carbonic anhydrase: An insight into the zinc binding site and into the active cavity through metal substitution

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