37 research outputs found

    Identifying the Host Galaxy of Gravitational Wave Signals

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    One of the goals of the current LIGO-GEO-Virgo science run is to identify transient gravitational wave (GW) signals in near real time to allow follow-up electromagnetic (EM) observations. An EM counterpart could increase the confidence of the GW detection and provide insight into the nature of the source. Current GW-EM campaigns target potential host galaxies based on overlap with the GW sky error box. We propose a new statistic to identify the most likely host galaxy, ranking galaxies based on their position, distance, and luminosity. We test our statistic with Monte Carlo simulations of GWs produced by coalescing binaries of neutron stars (NS) and black holes (BH), one of the most promising sources for ground-based GW detectors. Considering signals accessible to current detectors, we find that when imaging a single galaxy, our statistic correctly identifies the true host ~20% to ~50% of the time, depending on the masses of the binary components. With five narrow-field images the probability of imaging the true host increases to ~50% to ~80%. When collectively imaging groups of galaxies using large field-of-view telescopes, the probability improves to ~30% to ~60% for a single image and to ~70% to ~90% for five images. For the advanced generation of detectors (c. 2015+), and considering binaries within 100 Mpc (the reach of the galaxy catalogue used), the probability is ~40% for one narrow-field image, ~75% for five narrow-field images, ~65% for one wide-field image, and ~95% for five wide-field images, irrespective of binary type.Comment: 5 pages, 2 figure

    Does nonstationary noise in LIGO and Virgo affect the estimation of H0?

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    Gravitational-wave observations of binary neutron star mergers and their electromagnetic counterparts provide an independent measurement of the Hubble constant, H0H_0, through the standard-sirens approach. Current methods of determining H0H_0, such as measurements from the early universe and the local distance ladder, are in tension with one another. If gravitational waves are to break this tension a thorough understanding of systematic uncertainty for gravitational-wave observations is required. To accurately estimate the properties of gravitational-wave signals measured by LIGO and Virgo, we need to understand the characteristics of the detectors noise. Non-gaussian transients in the detector data and rapid changes in the instrument, known as non-stationary noise, can both add a systematic uncertainty to inferred results. We investigate how non-stationary noise affects the estimation of the luminosity distance of the source, and therefore of H0H_0. Using a population of 200 simulated binary neutron star signals, we show that non-stationary noise can bias the estimation of the luminosity distance by up to 2.4\%. However, only \sim15\% of binary neutron star signals would be affected around their merger time with non-stationary noise at a similar level to that seen in the first half of LIGO-Virgo's third observing run. Comparing the expected bias to other systematic uncertainties, we argue that non-stationary noise in the current generation of detectors will not be a limiting factor in resolving the tension on H0H_0 using standard sirens. Although, evaluating non-stationarity in gravitational-wave data will be crucial to obtain accurate estimates of H0H_0.Comment: 10 pages, 5 figures, 1 tabl

    Electromagnetic counterparts of gravitational-wave signals

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    Laura Nuttall and Christopher Berry review the potential of multimessenger astronomy with gravitational-wave observations

    Blip glitches in Advanced LIGO data

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    Blip glitches are short noise transients present in data from ground-based gravitational-wave observatories. These glitches resemble the gravitational-wave signature of massive binary black hole mergers. Hence, the sensitivity of transient gravitational-wave searches to such high-mass systems and other potential short duration sources is degraded by the presence of blip glitches. The origin and rate of occurrence of this type of glitch have been largely unknown. In this paper we explore the population of blip glitches in Advanced LIGO during its first and second observing runs. On average, we find that Advanced LIGO data contains approximately two blip glitches per hour of data. We identify four subsets of blip glitches correlated with detector auxiliary or environmental sensor channels, however the physical causes of the majority of blips remain unclear

    The Gravitational-wave Optical Transient Observer (GOTO)

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    The Gravitational-wave Optical Transient Observer (GOTO) is a wide-field telescope project focused on detecting optical counterparts to gravitational-wave sources. Each GOTO robotic mount holds eight 40 cm telescopes, giving an overall field of view of 40 square degrees. As of 2022 the first two GOTO mounts have been commissioned at the Roque de los Muchachos Observatory on La Palma, Canary Islands, and construction of the second node with two additional 8-telescope mounts has begin at Siding Spring Observatory in New South Wales, Australia. Once fully operational each GOTO mount will be networked to form a robotic, multi-site observatory, which will survey the entire visible sky every two nights and enable rapid follow-up detections of transient sources

    HBO1 is required for the maintenance of leukaemia stem cells.

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    Acute myeloid leukaemia (AML) is a heterogeneous disease characterized by transcriptional dysregulation that results in a block in differentiation and increased malignant self-renewal. Various epigenetic therapies aimed at reversing these hallmarks of AML have progressed into clinical trials, but most show only modest efficacy owing to an inability to effectively eradicate leukaemia stem cells (LSCs)1. Here, to specifically identify novel dependencies in LSCs, we screened a bespoke library of small hairpin RNAs that target chromatin regulators in a unique ex vivo mouse model of LSCs. We identify the MYST acetyltransferase HBO1 (also known as KAT7 or MYST2) and several known members of the HBO1 protein complex as critical regulators of LSC maintenance. Using CRISPR domain screening and quantitative mass spectrometry, we identified the histone acetyltransferase domain of HBO1 as being essential in the acetylation of histone H3 at K14. H3 acetylated at K14 (H3K14ac) facilitates the processivity of RNA polymerase II to maintain the high expression of key genes (including Hoxa9 and Hoxa10) that help to sustain the functional properties of LSCs. To leverage this dependency therapeutically, we developed a highly potent small-molecule inhibitor of HBO1 and demonstrate its mode of activity as a competitive analogue of acetyl-CoA. Inhibition of HBO1 phenocopied our genetic data and showed efficacy in a broad range of human cell lines and primary AML cells from patients. These biological, structural and chemical insights into a therapeutic target in AML will enable the clinical translation of these findings

    The politics and aesthetics of commemoration: national days in southern Africa

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    The contributions to the special section in this issue study recent independence celebrations and other national days in South Africa, Namibia, Zimbabwe, Madagascar and the Democratic Republic of Congo. They explore the role of national days in state-making and nation-building, and examine the performativity of nationalism and the role of performances in national festivities. Placing the case studies in a broader, comparative perspective, the introduction first discusses the role of the state in national celebrations, highlighting three themes: firstly, the political power-play and contested politics of memory involved in the creation of a country’s festive calendar; secondly, the relationship between state control of national days and civic or popular participation or contestation; and thirdly, the complex relationship between regional and ethnic loyalties and national identifications. It then turns to the role of performance and aesthetics in the making of nations in general, and in national celebrations in particular. Finally, we look at the different formats and meanings of national days in the region and address the question whether there is anything specific about national days in southern Africa as compared to other parts of the continent or national celebrations world-wide.Web of Scienc

    Searching for stochastic gravitational waves using data from the two colocated LIGO Hanford detectors

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    Searches for a stochastic gravitational-wave background (SGWB) using terrestrial detectors typically involve cross-correlating data from pairs of detectors. The sensitivity of such cross-correlation analyses depends, among other things, on the separation between the two detectors: the smaller the separation, the better the sensitivity. Hence, a colocated detector pair is more sensitive to a gravitational-wave background than a noncolocated detector pair. However, colocated detectors are also expected to suffer from correlated noise from instrumental and environmental effects that could contaminate the measurement of the background. Hence, methods to identify and mitigate the effects of correlated noise are necessary to achieve the potential increase in sensitivity of colocated detectors. Here we report on the first SGWB analysis using the two LIGO Hanford detectors and address the complications arising from correlated environmental noise. We apply correlated noise identification and mitigation techniques to data taken by the two LIGO Hanford detectors, H1 and H2, during LIGO’s fifth science run. At low frequencies, 40–460 Hz, we are unable to sufficiently mitigate the correlated noise to a level where we may confidently measure or bound the stochastic gravitational-wave signal. However, at high frequencies, 460–1000 Hz, these techniques are sufficient to set a 95% confidence level upper limit on the gravitational-wave energy density of Ω(f) < 7.7 × 10[superscript -4](f/900  Hz)[superscript 3], which improves on the previous upper limit by a factor of ~180. In doing so, we demonstrate techniques that will be useful for future searches using advanced detectors, where correlated noise (e.g., from global magnetic fields) may affect even widely separated detectors.National Science Foundation (U.S.)United States. National Aeronautics and Space AdministrationCarnegie TrustDavid & Lucile Packard FoundationAlfred P. Sloan Foundatio

    THE RATE OF BINARY BLACK HOLE MERGERS INFERRED FROM ADVANCED LIGO OBSERVATIONS SURROUNDING GW150914

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    A transient gravitational-wave signal, GW150914, was identi fi ed in the twin Advanced LIGO detectors on 2015 September 2015 at 09:50:45 UTC. To asse ss the implications of this discovery, the detectors remained in operation with unchanged con fi gurations over a period of 39 days around the time of t he signal. At the detection statistic threshold corresponding to that observed for GW150914, our search of the 16 days of simultaneous two-detector observational data is estimated to have a false-alarm rate ( FAR ) of < ́ -- 4.9 10 yr 61 , yielding a p -value for GW150914 of < ́ - 210 7 . Parameter estimation follo w-up on this trigger identi fi es its source as a binary black hole ( BBH ) merger with component masses ( )( ) = - + - + mm M ,36,29 12 4 5 4 4 at redshift = - + z 0.09 0.04 0.03 ( median and 90% credible range ) . Here, we report on the constraints these observations place on the rate of BBH coalescences. Considering only GW150914, assuming that all BBHs in the universe have the same masses and spins as this event, imposing a search FAR threshold of 1 per 100 years, and assuming that the BBH merger rate is constant in the comoving frame, we infer a 90% credible range of merger rates between – -- 2 53 Gpc yr 31 ( comoving frame ) . Incorporating all search triggers that pass a much lower threshold while accounting for the uncerta inty in the astrophysical origin of each trigger, we estimate a higher rate, ranging from – -- 13 600 Gpc yr 31 depending on assumptions about the BBH mass distribution. All together, our various rate estimat es fall in the conservative range – -- 2 600 Gpc yr 31

    Social Bonding and Nurture Kinship: Compatibility between Cultural and Biological Approaches

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