55 research outputs found
S-duality and 2d Topological QFT
We study the superconformal index for the class of N=2 4d superconformal
field theories recently introduced by Gaiotto. These theories are defined by
compactifying the (2,0) 6d theory on a Riemann surface with punctures. We
interpret the index of the 4d theory associated to an n-punctured Riemann
surface as the n-point correlation function of a 2d topological QFT living on
the surface. Invariance of the index under generalized S-duality
transformations (the mapping class group of the Riemann surface) translates
into associativity of the operator algebra of the 2d TQFT. In the A_1 case, for
which the 4d SCFTs have a Lagrangian realization, the structure constants and
metric of the 2d TQFT can be calculated explicitly in terms of elliptic gamma
functions. Associativity then holds thanks to a remarkable symmetry of an
elliptic hypergeometric beta integral, proved very recently by van de Bult.Comment: 25 pages, 11 figure
Localization of N=4 Superconformal Field Theory on S^1 x S^3 and Index
We provide the geometrical meaning of the superconformal index.
With this interpretation, the superconformal index can be realized
as the partition function on a Scherk-Schwarz deformed background. We apply the
localization method in TQFT to compute the deformed partition function since
the deformed action can be written as a -exact form. The
critical points of the deformed action turn out to be the space of flat
connections which are, in fact, zero modes of the gauge field. The one-loop
evaluation over the space of flat connections reduces to the matrix integral by
which the superconformal index is expressed.Comment: 42+1 pages, 2 figures, JHEP style: v1.2.3 minor corrections, v4 major
revision, conclusions essentially unchanged, v5 published versio
Counting Exceptional Instantons
We show how to obtain the instanton partition function of N=2 SYM with
exceptional gauge group EFG using blow-up recursion relations derived by
Nakajima and Yoshioka. We compute the two instanton contribution and match it
with the recent proposal for the superconformal index of rank 2 SCFTs with E6,
E7 global symmetry.Comment: 16 pages, references adde
Hilbert Series for Moduli Spaces of Two Instantons
The Hilbert Series (HS) of the moduli space of two G instantons on C^2, where
G is a simple gauge group, is studied in detail. For a given G, the moduli
space is a singular hyperKahler cone with a symmetry group U(2) \times G, where
U(2) is the natural symmetry group of C^2. Holomorphic functions on the moduli
space transform in irreducible representations of the symmetry group and hence
the Hilbert series admits a character expansion. For cases that G is a
classical group (of type A, B, C, or D), there is an ADHM construction which
allows us to compute the HS explicitly using a contour integral. For cases that
G is of E-type, recent index results allow for an explicit computation of the
HS. The character expansion can be expressed as an infinite sum which lives on
a Cartesian lattice that is generated by a small number of representations.
This structure persists for all G and allows for an explicit expressions of the
HS to all simple groups. For cases that G is of type G_2 or F_4, discrete
symmetries are enough to evaluate the HS exactly, even though neither ADHM
construction nor index is known for these cases.Comment: 53 pages, 9 tables, 24 figure
Genomics of Aerobic Cellulose Utilization Systems in Actinobacteria
Cellulose degrading enzymes have important functions in the biotechnology industry, including the production of biofuels from lignocellulosic biomass. Anaerobes including Clostridium species organize cellulases and other glycosyl hydrolases into large complexes known as cellulosomes. In contrast, aerobic actinobacteria utilize systems comprised of independently acting enzymes, often with carbohydrate binding domains. Numerous actinobacterial genomes have become available through the Genomic Encyclopedia of Bacteria and Archaea (GEBA) project. We identified putative cellulose-degrading enzymes belonging to families GH5, GH6, GH8, GH9, GH12, GH48, and GH51 in the genomes of eleven members of the actinobacteria. The eleven organisms were tested in several assays for cellulose degradation, and eight of the organisms showed evidence of cellulase activity. The three with the highest cellulase activity were Actinosynnema mirum, Cellulomonas flavigena, and Xylanimonas cellulosilytica. Cellobiose is known to induce cellulolytic enzymes in the model organism Thermobifida fusca, but only Nocardiopsis dassonvillei showed higher cellulolytic activity in the presence of cellobiose. In T. fusca, cellulases and a putative cellobiose ABC transporter are regulated by the transcriptional regulator CelR. Nine organisms appear to use the CelR site or a closely related binding site to regulate an ABC transporter. In some, CelR also regulates cellulases, while cellulases are controlled by different regulatory sites in three organisms. Mining of genome data for cellulose degradative enzymes followed by experimental verification successfully identified several actinobacteria species which were not previously known to degrade cellulose as cellulolytic organisms
Quivers, YBE and 3-manifolds
We study 4d superconformal indices for a large class of N=1 superconformal
quiver gauge theories realized combinatorially as a bipartite graph or a set of
"zig-zag paths" on a two-dimensional torus T^2. An exchange of loops, which we
call a "double Yang-Baxter move", gives the Seiberg duality of the gauge
theory, and the invariance of the index under the duality is translated into
the Yang-Baxter-type equation of a spin system defined on a "Z-invariant"
lattice on T^2. When we compactify the gauge theory to 3d, Higgs the theory and
then compactify further to 2d, the superconformal index reduces to an integral
of quantum/classical dilogarithm functions. The saddle point of this integral
unexpectedly reproduces the hyperbolic volume of a hyperbolic 3-manifold. The
3-manifold is obtained by gluing hyperbolic ideal polyhedra in H^3, each of
which could be thought of as a 3d lift of the faces of the 2d bipartite
graph.The same quantity is also related with the thermodynamic limit of the BPS
partition function, or equivalently the genus 0 topological string partition
function, on a toric Calabi-Yau manifold dual to quiver gauge theories. We also
comment on brane realization of our theories. This paper is a companion to
another paper summarizing the results.Comment: 61 pages, 16 figures; v2: typos correcte
M5-branes, toric diagrams and gauge theory duality
In this article we explore the duality between the low energy effective
theory of five-dimensional N=1 SU(N)^{M-1} and SU(M)^{N-1} linear quiver gauge
theories compactified on S^1. The theories we study are the five-dimensional
uplifts of four-dimensional superconformal linear quivers. We study this
duality by comparing the Seiberg-Witten curves and the Nekrasov partition
functions of the two dual theories. The Seiberg-Witten curves are obtained by
minimizing the worldvolume of an M5-brane with nontrivial geometry. Nekrasov
partition functions are computed using topological string theory. The result of
our study is a map between the gauge theory parameters, i.e., Coulomb moduli,
masses and UV coupling constants, of the two dual theories. Apart from the
obvious physical interest, this duality also leads to compelling mathematical
identities. Through the AGTW conjecture these five-dimentional gauge theories
are related to q-deformed Liouville and Toda SCFTs in two-dimensions. The
duality we study implies the relations between Liouville and Toda correlation
functions through the map we derive.Comment: 58 pages, 17 figures; v2: minor corrections, references adde
Expression Patterns of Protein Kinases Correlate with Gene Architecture and Evolutionary Rates
Protein kinase (PK) genes comprise the third largest superfamily that occupy âŒ2% of the human genome. They encode regulatory enzymes that control a vast variety of cellular processes through phosphorylation of their protein substrates. Expression of PK genes is subject to complex transcriptional regulation which is not fully understood.Our comparative analysis demonstrates that genomic organization of regulatory PK genes differs from organization of other protein coding genes. PK genes occupy larger genomic loci, have longer introns, spacer regions, and encode larger proteins. The primary transcript length of PK genes, similar to other protein coding genes, inversely correlates with gene expression level and expression breadth, which is likely due to the necessity to reduce metabolic costs of transcription for abundant messages. On average, PK genes evolve slower than other protein coding genes. Breadth of PK expression negatively correlates with rate of non-synonymous substitutions in protein coding regions. This rate is lower for high expression and ubiquitous PKs, relative to low expression PKs, and correlates with divergence in untranslated regions. Conversely, rate of silent mutations is uniform in different PK groups, indicating that differing rates of non-synonymous substitutions reflect variations in selective pressure. Brain and testis employ a considerable number of tissue-specific PKs, indicating high complexity of phosphorylation-dependent regulatory network in these organs. There are considerable differences in genomic organization between PKs up-regulated in the testis and brain. PK genes up-regulated in the highly proliferative testicular tissue are fast evolving and small, with short introns and transcribed regions. In contrast, genes up-regulated in the minimally proliferative nervous tissue carry long introns, extended transcribed regions, and evolve slowly.PK genomic architecture, the size of gene functional domains and evolutionary rates correlate with the pattern of gene expression. Structure and evolutionary divergence of tissue-specific PK genes is related to the proliferative activity of the tissue where these genes are predominantly expressed. Our data provide evidence that physiological requirements for transcription intensity, ubiquitous expression, and tissue-specific regulation shape gene structure and affect rates of evolution
Measurement of the Z/gamma* + b-jet cross section in pp collisions at 7 TeV
The production of b jets in association with a Z/gamma* boson is studied
using proton-proton collisions delivered by the LHC at a centre-of-mass energy
of 7 TeV and recorded by the CMS detector. The inclusive cross section for
Z/gamma* + b-jet production is measured in a sample corresponding to an
integrated luminosity of 2.2 inverse femtobarns. The Z/gamma* + b-jet cross
section with Z/gamma* to ll (where ll = ee or mu mu) for events with the
invariant mass 60 < M(ll) < 120 GeV, at least one b jet at the hadron level
with pT > 25 GeV and abs(eta) < 2.1, and a separation between the leptons and
the jets of Delta R > 0.5 is found to be 5.84 +/- 0.08 (stat.) +/- 0.72 (syst.)
+(0.25)/-(0.55) (theory) pb. The kinematic properties of the events are also
studied and found to be in agreement with the predictions made by the MadGraph
event generator with the parton shower and the hadronisation performed by
PYTHIA.Comment: Submitted to the Journal of High Energy Physic
Transcription Regulation of Sex-Biased Genes during Ontogeny in the Malaria Vector Anopheles gambiae
In Anopheles gambiae, sex-regulated genes are responsible for controlling gender dimorphism and are therefore crucial in determining the ability of female mosquitoes to transmit human malaria. The identification and functional characterization of these genes will shed light on the sexual development and maturation of mosquitoes and provide useful targets for genetic control measures aimed at reducing mosquito fertility and/or distorting the sex ratio
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