1,427 research outputs found
Transport-Health Equity Outcomes from mobile phone location data - a case study
The digital media convergence has innovated all the information and communication channels. ICTs have adapted to the reticular structure, which can be interpreted as a paradigm of today's Network Society, invoking a reorganization of man-machine relationship, interpersonal interactions and the ways of collecting, processing and storing data. Political communication and its processes of participation are not exempt from this evident change. The aim of this paper is to investigate the transformation dynamics that have taken place through the Internet and social networks, as effectively more democratic tools that are able to stimulate a bottom-up and grassroots participation, in some respects a disintermediate participation compared to the typical unidirectionality of analogue media. In identifying the specific characteristics of the interaction spaces offered by the web, we have examined the digital campaign strategy devised by the political parties during the Italian general election (4th March 2018). The results have returned an unprecedented scenario, in which the social media strategy plays a leading role in the different dimensions of political marketing. The web is proposed to become the ideal social arena for the meeting between political offer and demand
Evolution of the solar irradiance during the Holocene
Aims. We present a physically consistent reconstruction of the total solar
irradiance for the Holocene. Methods. We extend the SATIRE models to estimate
the evolution of the total (and partly spectral) solar irradiance over the
Holocene. The basic assumption is that the variations of the solar irradiance
are due to the evolution of the dark and bright magnetic features on the solar
surface. The evolution of the decadally averaged magnetic flux is computed from
decadal values of cosmogenic isotope concentrations recorded in natural
archives employing a series of physics-based models connecting the processes
from the modulation of the cosmic ray flux in the heliosphere to their record
in natural archives. We then compute the total solar irradiance (TSI) as a
linear combination of the jth and jth + 1 decadal values of the open magnetic
flux. Results. Reconstructions of the TSI over the Holocene, each valid for a
di_erent paleomagnetic time series, are presented. Our analysis suggests that
major sources of uncertainty in the TSI in this model are the heritage of the
uncertainty of the TSI since 1610 reconstructed from sunspot data and the
uncertainty of the evolution of the Earth's magnetic dipole moment. The
analysis of the distribution functions of the reconstructed irradiance for the
last 3000 years indicates that the estimates based on the virtual axial dipole
moment are significantly lower at earlier times than the reconstructions based
on the virtual dipole moment. Conclusions. We present the first physics-based
reconstruction of the total solar irradiance over the Holocene, which will be
of interest for studies of climate change over the last 11500 years. The
reconstruction indicates that the decadally averaged total solar irradiance
ranges over approximately 1.5 W/m2 from grand maxima to grand minima
Sensitivity of the UK clinical practice research datalink to detect neurodevelopmental effects of medicine exposure in utero:comparative analysis of an antiepileptic drug-exposed cohort
Introduction: Electronic healthcare data have several advantages over prospective observational studies, but the sensitivity of data on neurodevelopmental outcomes and its comparability with data generated through other methodologies is unknown. Objectives: The objectives of this study were to determine whether data from the UK Clinical Practice Research Datalink (CPRD) produces similar risk estimates to a prospective cohort study in relation to the risk of neurodevelopmental disorders (NDDs) following prenatal antiepileptic drug (AED) exposure. Methods: A cohort of mother–child pairs of women with epilepsy (WWE) was identified in the CPRD and matched to a cohort without epilepsy. The study period ran from 1 January 2000 to 31 March 2007 and children were required to be in the CPRD at age 6 years. AED exposure during pregnancy was determined from prescription data and children with an NDD diagnosis by 6 years were identified from Read clinical codes. The prevalence and risk of NDDs was calculated for mother–child pairs in WWE stratified by AED regimen and for those without epilepsy. Comparisons were made with the results of the prospective Liverpool and Manchester Neurodevelopment Group study which completed assessment on 201 WWE and 214 without epilepsy at age 6 years. Results: In the CPRD, 1018 mother–child pairs to WWE and 6048 to women without epilepsy were identified. The CPRD identified a lower prevalence of NDDs than the prospective study. In both studies, NDDs were more frequently reported in children of WWE than women without epilepsy, although the CPRD risk estimate was lower (2.16 vs. 0.96%, p < 0.001 and 7.46 vs. 1.87%, p = 0.0128). NDD prevalence differed across AED regimens but the CPRD data did not replicate the significantly higher risk of NDDs following in utero monotherapy valproate exposure (adjusted odds ratio [ORadj] 2.02, 95% confidence interval [CI] 0.52–7.86) observed in the prospective study (ORadj 6.05, 95% CI 1.65–24.53). Conclusion: It was possible to identify NDDs in the CPRD; however, the CPRD appears to under-record these outcomes. Larger studies are required to investigate further
Reducing the Social Gradient in Uptake of the NHS Colorectal Cancer Screening Programme Using a Narrative-Based Information Leaflet: A Cluster-Randomised Trial
Objective: To test the effectiveness of adding a narrative leaflet to the current information material delivered by the NHS English colorectal cancer (CRC) screening programme on reducing socioeconomic inequalities in uptake. / Participants: 150,417 adults (59-74 years) routinely invited to complete the guaiac Faecal Occult Blood test (gFOBt) in March 2013. / Design: A cluster randomised controlled trial (ISRCTN74121020) to compare uptake between two arms. The control arm received the standard NHS CRC screening information material (SI) and the intervention arm received the standard information plus a supplementary narrative leaflet, which had previously been shown to increase screening intentions (SI+N). Between group comparisons were made for uptake overall and across socioeconomic status (SES). Results: Uptake was 57.7% and did not differ significantly between the two trial arms (SI: 58.5%; SI+N: 56.7%; Odds Ratio = 0.93, 95% confidence interval: 0.81-1.06, p = 0.27). There was no interaction between group and SES quintile (p = 0.44). / Conclusions: Adding a narrative leaflet to existing information materials does not reduce the SES gradient in uptake. Despite the benefits of using a pragmatic trial design, the need to add to, rather than replace existing information may have limited the true value of an evidence-based intervention on behaviour
Effects of evidence-based strategies to reduce the socioeconomic gradient of uptake in the English NHS Bowel Cancer Screening Programme (ASCEND): four cluster-randomised controlled trials
This study is funded by the National Institute for Health Research (NIHR) Programme Grants for Applied Research Programme ( RP-PG-0609-10106 ) and partly supported by the NIHR Collaboration for Leadership in Applied Health Research and Care (CLAHRC) North Thames (MCT and RR
Measurements of double-helicity asymmetries in inclusive production in longitudinally polarized collisions at GeV
We report the double helicity asymmetry, , in inclusive
production at forward rapidity as a function of transverse momentum
and rapidity . The data analyzed were taken during
GeV longitudinally polarized collisions at the Relativistic Heavy Ion
Collider (RHIC) in the 2013 run using the PHENIX detector. At this collision
energy, particles are predominantly produced through gluon-gluon
scatterings, thus is sensitive to the gluon polarization
inside the proton. We measured by detecting the decay
daughter muon pairs within the PHENIX muon spectrometers in the
rapidity range . In this kinematic range, we measured the
to be ~(stat)~~(syst). The
can be expressed to be proportional to the product of the
gluon polarization distributions at two distinct ranges of Bjorken : one at
moderate range where recent RHIC data of jet and
double helicity spin asymmetries have shown evidence for significant gluon
polarization, and the other one covering the poorly known small- region . Thus our new results could be used to further
constrain the gluon polarization for .Comment: 335 authors, 10 pages, 4 figures, 3 tables, 2013 data. Version
accepted for publication by Phys. Rev. D. Plain text data tables for the
points plotted in figures for this and previous PHENIX publications are (or
will be) publicly available at http://www.phenix.bnl.gov/papers.htm
Nuclear dependence of the transverse single-spin asymmetry in the production of charged hadrons at forward rapidity in polarized , Al, and Au collisions at GeV
We report on the nuclear dependence of transverse single-spin asymmetries
(TSSAs) in the production of positively-charged hadrons in polarized
, Al and Au collisions at
GeV. The measurements have been performed at forward
rapidity () over the range of GeV and
. We observed a positive asymmetry for
positively-charged hadrons in \polpp collisions, and a significantly reduced
asymmetry in + collisions. These results reveal a nuclear
dependence of charged hadron in a regime where perturbative techniques
are relevant. These results provide new opportunities to use \polpA collisions
as a tool to investigate the rich phenomena behind TSSAs in hadronic collisions
and to use TSSA as a new handle in studying small-system collisions.Comment: 303 authors from 66 institutions, 9 pages, 2 figures, 1 table. v1 is
version accepted for publication in Physical Review Letters. Plain text data
tables for the points plotted in figures for this and previous PHENIX
publications are (or will be) publicly available at
http://www.phenix.bnl.gov/papers.htm
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