Recent fold growth and drainage development: The Janauri and Chandigarh anticlines in the Siwalik foothills, northwest India

International audienceThe active growth of a fault-and-thrust belt in frontal zones of Himalaya is a prominent topographical feature, extending 2500 km from Assam to Pakistan. In this paper, kinematical analysis of frontal anticlines and spatial mapping of active faults based on geomorphological features such as drainage pattern development, fault scarps and uplifted Quaternary alluvial fans are presented. We analyse the geomorphic and hydrographic expressions of the Chandigarh and the Janauri active anticlines in the NW India Siwaliks. To investigate the morphological scenario during the folding process, we used spatial imagery, geomorphometric parameters extracted from digital elevation models and fieldwork. The approach presented here involves analysis of topography and drainage incision of selected landforms to detect growth of active anticlines and transfer faults. Landforms that indicate active folding above a southwest-dipping frontal thrust and a northeastdipping back-thrust are described. Along-strike differences in ridge morphology are measured to describe the interaction of river channel patterns with folds and thrust faults and to define history of anticline growt

New geomorphic criteria on lateral propagation of blind thrust-related fold growth accommodating oblique convergence

International audienceThe aim of this contribution is to show the styles of growing anticlines and the ways in which they accommodate oblique convergence through proximal foreland basins and intramontane basins. The four natural examples of individual fault-related-folds are: the Chandigarh anticline in the Siwalik foothills of Himalaya (NW India), the Pakuashan anticline in the western foothills of Central Range (Taiwan), the J. Bou Dhar-Tamdafelt fold belt (Morocco) and the Marand anticline in the North-Tabriz Fault-Zone (NW Iran). The evolution of these geomorphic criteria and drainage patterns shows evidence of lateral propagation of folds accommodating oblique convergence. This paper focuses on the geomorphic indicators that could be used to provide information on the timing of fault-related folding and direction of lateral propagation. Several tectonic scenarios has been analysed and an attempt has been made to delineate the sequential evolution of anticlines accommodating oblique convergence

Morphotectonic evolution of the Jebel Bou Naceur in the South Middle Atlas Fault Zone (Morocco)

International audienceIn eastern Morocco, fault-related folds develop above the South Middle Atlas fault that separates the J. Bou Naceur 'pop-up' structure and the Missour Basin, filled with alluvial sediments. Using a combination of surfaces, field observations and digital topographic information, we have investigated several geomorphic criteria and geometry of depositional surfaces governed by the relief's growth. The propagation of the deformation is recorded by warped segmented fans that moved southeastward and wellpreserved geomorphological features of tectonic origin. Uplift of the anticline hinges and acceleration of valley incision since the Late Pliocene are considered a consequence of the ongoing NW-SE convergence between Africa and Eurasia. A scenario of morphotectonic evolution of this active mountain front is proposed

Preventing acute decrease in renal function induced by coronary angiography (PRECORD): a prospective randomized trial

SummaryBackgroundInfusion of saline attenuates the decrease in renal function induced by radiographic contrast agents among patients with chronic renal insufficiency.AimThe Preventing Renal alteration in Coronary Disease (PRECORD) trial was a randomized trial to assess the effect on renal function of saline infusion during and after coronary angiography in 201 patients without severe chronic renal insufficiency (serum creatinine<140μmol/L).MethodsAll patients received standard oral hydration: 2000mL of tap water within the 24hours after coronary angiography. Patients were randomized before the procedure to intravenous hydration (1000mL of 0.9% saline infusion) or no additional hydration. The infusion was started in the catheterization laboratory and continued for 24hours. The primary endpoint was the change in calculated creatinine clearance between baseline and 24hours after coronary angiography. The same ionic low osmolar radiographic contrast agent (ioxaglate) was used in all patients.ResultsBoth groups had similar baseline characteristics, including age, serum creatinine, volume of contrast and proportion of patients undergoing ad hoc coronary angioplasty. The overall decrease in serum creatinine clearance 24hours after the procedure was –3.44 (0.68)mL/min. The change in serum creatinine clearance 24hours after the procedure was –2.81 (1.07)mL/min in the infusion group vs –4.09 (0.91)mL/min in the control group (p=0.38).ConclusionRenal function is altered only slightly 24hours after coronary angiography with standard oral hydration alone and is not affected by saline infusion started at the beginning of coronary angiography, even in patients with mild-to-moderate renal dysfunction

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Effets induits des grandes infrastructures : synthèse de l'analyse bibliographique

Ce rapport constitue la synthèse de l'étude bibliographique réalisée dans le cadre de l'action du programme, menée sur trois ans, dont il est la première phase, et qui porte plus largement sur la problématique des effets induits des grandes infrastructures . L'analyse a été volontairement limitée à une cinquantaine de références centrées d'une part, sur les effets socio-économiques, il s'agit d'études réalisées en application de la loi d'orientation sur les transports intérieurs, et d'autre part, sur les infrastructures autoroutières et voies ferrées à grande vitesse. L'objectif de cette approche vise non seulement à dresser un état des lieux de la connaissance et des pratiques d'études sur le thème des effets induits, mais aussi, à repérer les marges de progrès et de renouvellements à la fois dans les concepts et les méthodes. En conséquence, le rapport est conçu selon deux parties : • la première consacrée à l'état des connaissances et des pratiques, notamment sur le concept d'effets induits et sur la mesure de ces effets, • la deuxième développée autour du constat que l'évolution de la représentation spatiale rend nécessaire le renouvellement des concepts et des pratiques

Effect of physical inactivity on the oxidation of saturated and monounsaturated dietary Fatty acids: results of a randomized trial

OBJECTIVES: Changes in the way dietary fat is metabolized can be considered causative in obesity. The role of sedentary behavior in this defect has not been determined. We hypothesized that physical inactivity partitions dietary fats toward storage and that a resistance exercise training program mitigates storage

OBEDIS Core Variables Project : European Expert Guidelines on a Minimal Core Set of Variables to Include in Randomized, Controlled Clinical Trials of Obesity Interventions

Heterogeneity of interindividual and intraindividual responses to interventions is often observed in randomized, controlled trials for obesity. To address the global epidemic of obesity and move toward more personalized treatment regimens, the global research community must come together to identify factors that may drive these heterogeneous responses to interventions. This project, called OBEDIS (OBEsity Diverse Interventions Sharing - focusing on dietary and other interventions), provides a set of European guidelines for a minimal set of variables to include in future clinical trials on obesity, regardless of the specific endpoints. Broad adoption of these guidelines will enable researchers to harmonize and merge data from multiple intervention studies, allowing stratification of patients according to precise phenotyping criteria which are measured using standardized methods. In this way, studies across Europe may be pooled for better prediction of individuals' responses to an intervention for obesity - ultimately leading to better patient care and improved obesity outcomes.Peer reviewe