564 research outputs found
Hyperspectral Data Analysis in R: The hsdar Package
Hyperspectral remote sensing is a promising tool for a variety of applications including ecology, geology, analytical chemistry and medical research. This article presents the new hsdar package for R statistical software, which performs a variety of analysis steps taken during a typical hyperspectral remote sensing approach. The package introduces a new class for efficiently storing large hyperspectral data sets such as hyperspectral cubes within R. The package includes several important hyperspectral analysis tools such as continuum removal, normalized ratio indices and integrates two widely used radiation transfer models. In addition, the package provides methods to directly use the functionality of the caret package for machine learning tasks. Two case studies demonstrate the package's range of functionality: First, plant leaf chlorophyll content is estimated and second, cancer in the human larynx is detected from hyperspectral data
Reduced endothelin-1– and nitric oxide–mediated arteriolar tone in hypertensive renal transplant recipients
Reduced endothelin-1– and nitric oxide–mediated arteriolar tone in hypertensive renal transplant recipients.BackgroundThe prevalence of hypertension is high in renal transplant recipients. It has been suggested that calcineurin inhibitors (CI) contribute to the development of post-transplant hypertension by stimulating endothelin (ET-1)-mediated and/or reducing nitric oxide (NO)-mediated vascular tone.MethodsWe tested this hypothesis using 2 groups of renal transplant recipients [normotensive patients without a need for antihypertensive medication (Normo-Tx), and hypertensive patients requiring antihypertensives (Hyper-Tx)] in the presence of CI-based immunosuppression. In addition, we studied matched control subjects (C). BQ 123 (ET-A receptor antagonist), BQ123 + BQ788 (ET-A/B-receptor antagonist), ET-1, L-NMMA (NO-synthase inhibitor), acetylcholine (ACH; endothelium-dependent vasodilator), glyceroltrinitrate (GTN, NO donor), and norepinephrine (NE, endothelium-independent vasoconstrictor) were infused into the brachial artery. Forearm blood flow (FBF) was measured by venous occlusion plethysmography.ResultsEndothelium-independent vasomotion in response to GTN and NE was similar in all groups. Vascular responses to selective and combined blockade of ET receptors in both Normo-Tx and Hyper-Tx did not exceed those of C. In fact, we observed a significantly lower increase in FBF after BQ 123 (P = 0.03), as well as after BQ 123/788 (P = 0.03) in Hyper-Tx compared with Normo-Tx. This was associated with an increased vascular sensitivity to exogenous ET-1 in Hyper-Tx compared with Normo-Tx (P = 0.04). Vasoconstriction after L-NMMA was reduced in Hyper-Tx compared with Normo-Tx (P = 0.015), while the response to ACH was reduced in both groups of Tx patients to a similar degree (P = 0.005 vs. C).ConclusionOur results do not support a major role for the vascular endothelin system in the hypertension of renal transplant recipients, whereas deficient baseline NO production may be a contributing factor
The Role of Bile in the Regulation of Exocrine Pancreatic Secretion
As early as 1926 Mellanby (1) was able to show that introduction of bile into the duodenum of anesthetized cats produces a copious flow of pancreatic juice. In conscious dogs, Ivy & Lueth (2) reported, bile is only a weak stimulant of pancreatic secretion. Diversion of bile from the duodenum, however, did not influence pancreatic volume secretion stimulated by a meal (3,4). Moreover, Thomas & Crider (5) observed that bile not only failed to stimulate the secretion of pancreatic juice but also abolished the pancreatic response to intraduodenally administered peptone or soap
The GALEX Arecibo SDSS Survey II: The Star Formation Efficiency of Massive Galaxies
We use measurements of the HI content, stellar mass and star formation rates
in ~190 massive galaxies with stellar masses greater than 10^10 Msun, obtained
from the Galex Arecibo SDSS Survey (GASS) described in Paper I (Catinella et
al. 2010) to explore the global scaling relations associated with the
bin-averaged ratio of the star formation rate over the HI mass, which we call
the HI-based star formation efficiency (SFE). Unlike the mean specific star
formation rate, which decreases with stellar mass and stellar mass surface
density, the star formation efficiency remains relatively constant across the
sample with a value close to SFE = 10^-9.5 yr^-1 (or an equivalent gas
consumption timescale of ~3 Gyr). Specifically, we find little variation in SFE
with stellar mass, stellar mass surface density, NUV-r color and concentration.
We interpret these results as an indication that external processes or feedback
mechanisms that control the gas supply are important for regulating star
formation in massive galaxies. An investigation into the detailed distribution
of SFEs reveals that approximately 5% of the sample shows high efficiencies
with SFE > 10^-9 yr^-1, and we suggest that this is very likely due to a
deficiency of cold gas rather than an excess star formation rate. Conversely,
we also find a similar fraction of galaxies that appear to be gas-rich for
their given specific star-formation rate, although these galaxies show both a
higher than average gas fraction and lower than average specific star formation
rate. Both of these populations are plausible candidates for "transition"
galaxies, showing potential for a change (either decrease or increase) in their
specific star formation rate in the near future. We also find that 36+/-5% of
the total HI mass density and 47+/-5% of the total SFR density is found in
galaxies with stellar mass greater than 10^10 Msun. [abridged]Comment: 18 pages, 11 figures. Accepted for publication in MNRAS. GASS
publications and released data can be found at
http://www.mpa-garching.mpg.de/GASS/index.ph
Neutral Hydrogen Gas in Interacting Galaxies: The NGC 1511 galaxy group
We present HI line and 20-cm radio continuum observations of the NGC 1511
galaxy group obtained with the Australia Telescope Compact Array. The data
reveal an extended, rather disturbed HI distribution for the peculiar starburst
galaxy NGC 1511 and a narrow bridge to its small companion galaxy, NGC 1511B,
which has been severely distorted by the interaction/collision between the two
galaxies. No stellar counterpart to the gaseous bridge has been detected. In
addition, we find that the peculiar optical ridge to the east of NGC 1511 is
probably the stellar remnant of a galaxy completed disrupted by interactions
with NGC 1511. The slightly more distant neighbour, NGC 1511A, shows a regular
HI velocity field and no obvious signs of interactions. Radio continuum
emission from NGC 1511 reveals three prominent sources on top of a more
diffuse, extended distribution. We derive an overall star formation rate of 7
Msun/yr. The most enhanced star formation is found in the south-eastern part of
the disk, coincident with several bright HII regions, and closest to the
peculiar optical ridge. No continuum emission was detected in the companions,
but NGC 1511B appears to show an HII region at its faint western edge, closest
to NGC 1511. The group displays a prime example of interaction-induced star
formation activity.Comment: 9 pages, 8 figures, accepted for publication in MNRA
A chemical understanding for the enhanced hydrogen tunnelling in hydroperoxidation of linoleic acid catalysed by soybean lipoxygenase-1
The reaction path of the Interacting-State Model (ISM) is used with the Transition-State Theory (TST) and the semiclassical correction for tunnelling (ISM/scTST) to calculate the rates of H-atom abstraction from C(11) of linoleic acid catalysed by soybean lipoxygenase-1 (SLO), as well as of an analogous uncatalysed reaction in solution. The calculated hydrogen-atom transfer rates, their temperature dependency and kinetic isotope effect (KIE) are in good agreement with the experimental data. ISM/scTST calculations reveal the hypersensitivity of the rate to protein dynamics when the hydrogen bonding to a carbon atom is present in the reaction coordinate
Recommended from our members
Solar neutrino with Borexino: results and perspectives
Borexino is a unique detector able to perform measurement of solar neutrinos
fluxes in the energy region around 1 MeV or below due to its low level of
radioactive background. It was constructed at the LNGS underground laboratory
with a goal of solar Be neutrino flux measurement with 5\% precision. The
goal has been successfully achieved marking the end of the first stage of the
experiment. A number of other important measurements of solar neutrino fluxes
have been performed during the first stage. Recently the collaboration
conducted successful liquid scintillator repurification campaign aiming to
reduce main contaminants in the sub-MeV energy range. With the new levels of
radiopurity Borexino can improve existing and challenge a number of new
measurements including: improvement of the results on the Solar and terrestrial
neutrino fluxes measurements; measurement of pp and CNO solar neutrino fluxes;
search for non-standard interactions of neutrino; study of the neutrino
oscillations on the short baseline with an artificial neutrino source (search
for sterile neutrino) in context of SOX project.Comment: 15 pages, 4 figure
Recommended from our members
Spectroscopy of geo-neutrinos from 2056 days of Borexino data
We report an improved geo-neutrino measurement with Borexino from 2056 days
of data taking. The present exposure is
protonyr. Assuming a chondritic Th/U mass ratio of 3.9, we obtain geo-neutrino events. The null
observation of geo-neutrinos with Borexino alone has a probability of (5.9). A geo-neutrino signal from the mantle is
obtained at 98\% C.L. The radiogenic heat production for U and Th from the
present best-fit result is restricted to the range 23-36 TW, taking into
account the uncertainty on the distribution of heat producing elements inside
the Earth.Comment: 4 pages, 4 figure
The Main Results of the Borexino Experiment
The main physical results on the registration of solar neutrinos and the
search for rare processes obtained by the Borexino collaboration to date are
presented.Comment: 8 pages, 8 figgures, To be published as Proceedings of the Third
Annual Large Hadron Collider Physics Conference, St. Petersburg, Russia, 201
Measurement of neutrino flux from the primary proton--proton fusion process in the Sun with Borexino detector
Neutrino produced in a chain of nuclear reactions in the Sun starting from
the fusion of two protons, for the first time has been detected in a real-time
detector in spectrometric mode. The unique properties of the Borexino detector
provided an oppurtunity to disentangle pp-neutrino spectrum from the background
components. A comparison of the total neutrino flux from the Sun with Solar
luminosity in photons provides a test of the stability of the Sun on the
10 years time scale, and sets a strong limit on the power production in
the unknown energy sources in the Sun of no more than 4\% of the total energy
production at 90\% C.L.Comment: 15 pages, 2 tables, 3 figure
- …