O uso de dispositivos móveis na sala de aula: pedagogia de projetos e tecnologias móveis na educação superior

This study reports partial results from the research entitled "Project Method and Mobile Technologies: Potentialities and Challenges to the Teaching and Learning Processes in Marketing Undergraduation Course", developed within the Graduate Program in Education of the Universidade do Oeste Paulista (UNOESTE/Presidente Prudente/SP/Brazil). This research has adopted as general objective to analyze how mobile technologies can be articulated to the development of work projects, aiming at their integration to the pedagogical practices in higher education. The research was based on the qualitative approach and was carried out in the form of intervention research. Data were collected through participant observation, semi-structured interview, questionnaire and focus group. As context, we adopted the reality of the Marketing Undergradtion Course, offered by a private higher education institution (HEI) from, located in the city of Lins/SP/Brazil. The results obtained provided an understanding of the profile of higher education students in the contemporary era and the need for (re)construction of pedagogical practices to these students. The importance of work projects as an opportunity to adopt an active methodology articulated to mobile technologies in higher education was also evidenced.El presente estudio relata resultados parciales de la investigación titulada "Pedagogía de Proyectos y las Tecnologías Móviles: Potencialidades y Desafíos a los Procesos de Enseñanza y de Aprendizaje en el Curso Superior de Marketing", desarrollada en el ámbito del Programa de Postgrado en Educación en la Universidad del Oeste Paulista (UNOESTE/Presidente Prudente/SP/Brasil). Esta investigación adoptó como objetivo general analizar cómo las tecnologías móviles pueden ser articuladas al desarrollo de proyectos de trabajo, buscando su integración a las prácticas pedagógicas en la enseñanza superior. La investigación se desarrolló basadas en el enfoque cualitativo y se llevó a cabo en forma de investigación-intervención. Los datos fueron recolectados por medio de la observación participante, entrevista semiestructurada, cuestionario y grupo focal. Como contexto, se adoptó la realidad del curso superior de Marketing, ofrecido por una IES de la red privada, situada en el municipio de Lins/SP/Brasil. Los resultados alcanzados propiciaron la comprensión del perfil de los estudiantes de enseñanza superior en la era contemporánea y la necesidad de (re) construcción de las prácticas pedagógicas ante ese alunado. Se evidenció la importancia de los proyectos de trabajo como una oportunidad de adoptar una metodología activa articulada a las tecnologías móviles en la enseñanza superior. O presente estudo relata resultados parciais da pesquisa intitulada “Pedagogia de Projetos e as Tecnologias Móveis: Potencialidades e Desafios aos Processos de Ensino e de Aprendizagem no Curso Superior de Marketing”, desenvolvida no âmbito do Programa de Pós-Graduação em Educação na Universidade do Oeste Paulista (UNOESTE/Presidente Prudente/SP/Brasil). Esta investigação adotou como objetivo geral analisar como as tecnologias móveis podem ser articuladas ao desenvolvimento de projetos de trabalho, visando à sua integração às práticas pedagógicas no ensino superior. A investigação se desenvolveu embasada na abordagem qualitativa e foi realizada sob a forma de pesquisa-intervenção. Os dados foram coletados por meio da observação participante, entrevista semiestruturada, questionário e grupo focal. Como contexto, adotou-se a realidade do curso superior de Marketing, ofertado por uma IES da rede privada, situada no município de Lins/SP/Brasil. Os resultados alcançados propiciaram a compreensão do perfil dos estudantes de ensino superior na era contemporânea e a necessidade de (re)construção das práticas pedagógicas diante desse alunado. Evidenciou-se ainda a importância dos projetos de trabalho como uma oportunidade de adotar uma metodologia ativa articulada às tecnologias móveis no ensino superior

Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae Family

Endosymbiont-bearing trypanosomatids have been considered excellent models for the study of cell evolution because the host protozoan co-evolves with an intracellular bacterium in a mutualistic relationship. Such protozoa inhabit a single invertebrate host during their entire life cycle and exhibit special characteristics that group them in a particular phylogenetic cluster of the Trypanosomatidae family, thus classified as monoxenics. in an effort to better understand such symbiotic association, we used DNA pyrosequencing and a reference-guided assembly to generate reads that predicted 16,960 and 12,162 open reading frames (ORFs) in two symbiont-bearing trypanosomatids, Angomonas deanei (previously named as Crithidia deanei) and Strigomonas culicis (first known as Blastocrithidia culicis), respectively. Identification of each ORF was based primarily on TriTrypDB using tblastn, and each ORF was confirmed by employing getorf from EMBOSS and Newbler 2.6 when necessary. the monoxenic organisms revealed conserved housekeeping functions when compared to other trypanosomatids, especially compared with Leishmania major. However, major differences were found in ORFs corresponding to the cytoskeleton, the kinetoplast, and the paraflagellar structure. the monoxenic organisms also contain a large number of genes for cytosolic calpain-like and surface gp63 metalloproteases and a reduced number of compartmentalized cysteine proteases in comparison to other TriTryp organisms, reflecting adaptations to the presence of the symbiont. the assembled bacterial endosymbiont sequences exhibit a high A+T content with a total of 787 and 769 ORFs for the Angomonas deanei and Strigomonas culicis endosymbionts, respectively, and indicate that these organisms hold a common ancestor related to the Alcaligenaceae family. Importantly, both symbionts contain enzymes that complement essential host cell biosynthetic pathways, such as those for amino acid, lipid and purine/pyrimidine metabolism. These findings increase our understanding of the intricate symbiotic relationship between the bacterium and the trypanosomatid host and provide clues to better understand eukaryotic cell evolution.Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)ERC AdG SISYPHEUniv Fed Rio de Janeiro, Inst Biofis Carlos Chagas Filho, Lab Ultraestrutura Celular Hertha Meyer, BR-21941 Rio de Janeiro, BrazilUniv Fed Rio de Janeiro, Inst Biofis Carlos Chagas Filho, Lab Metab Macromol Firmino Torres de Castro, BR-21941 Rio de Janeiro, BrazilLab Bioinformat, Lab Nacl Computacao Cient, Rio de Janeiro, BrazilINRIA Grenoble Rhone Alpes, BAMBOO Team, Villeurbanne, FranceUniv Lyon 1, CNRS, UMR5558, Lab Biometrie & Biol Evolut, F-69622 Villeurbanne, FranceUniv Estadual Campinas, Inst Biol, Dept Genet Evolucao & Bioagentes, São Paulo, BrazilUniv São Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Dept Ciencias Farmaceut, São Paulo, BrazilLab Nacl Ciencia & Tecnol Bioetano, São Paulo, BrazilUniv Fed Minas Gerais, Inst Ciencias Biol, Dept Bioquim & Imunol, Belo Horizonte, MG, BrazilUniv Fed Goias, Inst Ciencias Biol, Mol Biol Lab, Goiania, Go, BrazilFundacao Oswaldo Cruz, Inst Carlos Chagas, Lab Biol Mol Tripanossomatideos, Curitiba, Parana, BrazilFundacao Oswaldo Cruz, Inst Carlos Chagas, Lab Genom Func, Curitiba, Parana, BrazilUniv Estadual Campinas, Ctr Pluridisciplinar Pesquisas Quim Biol & Agr, São Paulo, BrazilUniv Fed Minas Gerais, Inst Ciencias Biol, Dept Parasitol, Belo Horizonte, MG, BrazilUniv Fed Santa Catarina, Dept Microbiol Imunol & Parasitol, Ctr Ciencias Biol, Lab Protozool & Bioinformat, Florianopolis, SC, BrazilUniv Fed Vicosa, Dept Bioquim & Biol Mol, Ctr Ciencias Biol & Saude, Vicosa, MG, BrazilInst Butantan, Lab Especial Ciclo Celular, São Paulo, BrazilUniv São Paulo, Dept Biol, Fac Filosofia Ciencias & Letras Ribeirao Preto, São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Dept Microbiol Imunol & Parasitol, São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Dept Microbiol Imunol & Parasitol, São Paulo, BrazilWeb of Scienc

Diretriz da Sociedade Brasileira de Cardiologia sobre Diagnóstico e Tratamento de Pacientes com Cardiomiopatia da Doença de Chagas

This guideline aimed to update the concepts and formulate the standards of conduct and scientific evidence that support them, regarding the diagnosis and treatment of the Cardiomyopathy of Chagas disease, with special emphasis on the rationality base that supported it.  Chagas disease in the 21st century maintains an epidemiological pattern of endemicity in 21 Latin American countries. Researchers and managers from endemic and non-endemic countries point to the need to adopt comprehensive public health policies to effectively control the interhuman transmission of T. cruzi infection, and to obtain an optimized level of care for already infected individuals, focusing on diagnostic and therapeutic opportunistic opportunities.   Pathogenic and pathophysiological mechanisms of the Cardiomyopathy of Chagas disease were revisited after in-depth updating and the notion that necrosis and fibrosis are stimulated by tissue parasitic persistence and adverse immune reaction, as fundamental mechanisms, assisted by autonomic and microvascular disorders, was well established. Some of them have recently formed potential targets of therapies.  The natural history of the acute and chronic phases was reviewed, with enhancement for oral transmission, indeterminate form and chronic syndromes. Recent meta-analyses of observational studies have estimated the risk of evolution from acute and indeterminate forms and mortality after chronic cardiomyopathy. Therapeutic approaches applicable to individuals with Indeterminate form of Chagas disease were specifically addressed. All methods to detect structural and/or functional alterations with various cardiac imaging techniques were also reviewed, with recommendations for use in various clinical scenarios. Mortality risk stratification based on the Rassi score, with recent studies of its application, was complemented by methods that detect myocardial fibrosis.  The current methodology for etiological diagnosis and the consequent implications of trypanonomic treatment deserved a comprehensive and in-depth approach. Also the treatment of patients at risk or with heart failure, arrhythmias and thromboembolic events, based on pharmacological and complementary resources, received special attention. Additional chapters supported the conducts applicable to several special contexts, including t. cruzi/HIV co-infection, risk during surgeries, in pregnant women, in the reactivation of infection after heart transplantation, and others.     Finally, two chapters of great social significance, addressing the structuring of specialized services to care for individuals with the Cardiomyopathy of Chagas disease, and reviewing the concepts of severe heart disease and its medical-labor implications completed this guideline.Esta diretriz teve como objetivo principal atualizar os conceitos e formular as normas de conduta e evidências científicas que as suportam, quanto ao diagnóstico e tratamento da CDC, com especial ênfase na base de racionalidade que a embasou. A DC no século XXI mantém padrão epidemiológico de endemicidade em 21 países da América Latina. Investigadores e gestores de países endêmicos e não endêmicos indigitam a necessidade de se adotarem políticas abrangentes, de saúde pública, para controle eficaz da transmissão inter-humanos da infecção pelo T. cruzi, e obter-se nível otimizado de atendimento aos indivíduos já infectados, com foco em oportunização diagnóstica e terapêutica. Mecanismos patogênicos e fisiopatológicos da CDC foram revisitados após atualização aprofundada e ficou bem consolidada a noção de que necrose e fibrose sejam estimuladas pela persistência parasitária tissular e reação imune adversa, como mecanismos fundamentais, coadjuvados por distúrbios autonômicos e microvasculares. Alguns deles recentemente constituíram alvos potenciais de terapêuticas. A história natural das fases aguda e crônica foi revista, com realce para a transmissão oral, a forma indeterminada e as síndromes crônicas. Metanálises recentes de estudos observacionais estimaram o risco de evolução a partir das formas aguda e indeterminada e de mortalidade após instalação da cardiomiopatia crônica. Condutas terapêuticas aplicáveis aos indivíduos com a FIDC foram abordadas especificamente. Todos os métodos para detectar alterações estruturais e/ou funcionais com variadas técnicas de imageamento cardíaco também foram revisados, com recomendações de uso nos vários cenários clínicos. Estratificação de risco de mortalidade fundamentada no escore de Rassi, com estudos recentes de sua aplicação, foi complementada por métodos que detectam fibrose miocárdica. A metodologia atual para diagnóstico etiológico e as consequentes implicações do tratamento tripanossomicida mereceram enfoque abrangente e aprofundado. Também o tratamento de pacientes em risco ou com insuficiência cardíaca, arritmias e eventos tromboembólicos, baseado em recursos farmacológicos e complementares, recebeu especial atenção. Capítulos suplementares subsidiaram as condutas aplicáveis a diversos contextos especiais, entre eles o da co-infecção por T. cruzi/HIV, risco durante cirurgias, em grávidas, na reativação da infecção após transplante cardíacos, e outros.    Por fim, dois capítulos de grande significado social, abordando a estruturação de serviços especializados para atendimento aos indivíduos com a CDC, e revisando os conceitos de cardiopatia grave e suas implicações médico-trabalhistas completaram esta diretriz.&nbsp

The Genome of Anopheles darlingi, the main neotropical malaria vector

Anopheles darlingi is the principal neotropical malaria vector, responsible for more than a million cases of malaria per year on the American continent. Anopheles darlingi diverged from the African and Asian malaria vectors ∼100 million years ago (mya) and successfully adapted to the New World environment. Here we present an annotated reference A. darlingi genome, sequenced from a wild population of males and females collected in the Brazilian Amazon. A total of 10 481 predicted protein-coding genes were annotated, 72% of which have their closest counterpart in Anopheles gambiae and 21% have highest similarity with other mosquito species. In spite of a long period of divergent evolution, conserved gene synteny was observed between A. darlingi and A. gambiae. More than 10 million single nucleotide polymorphisms and short indels with potential use as genetic markers were identified. Transposable elements correspond to 2.3% of the A. darlingi genome. Genes associated with hematophagy, immunity and insecticide resistance, directly involved in vectorhuman and vectorparasite interactions, were identified and discussed. This study represents the first effort to sequence the genome of a neotropical malaria vector, and opens a new window through which we can contemplate the evolutionary history of anopheline mosquitoes. It also provides valuable information that may lead to novel strategies to reduce malaria transmission on the South American continent. The A. darlingi genome is accessible at www.labinfo.lncc.br/index.php/anopheles- darlingi. © 2013 The Author(s)

Atuação do departamento de marketing em uma instituição de ensino superior – IES

http://dx.doi.org/10.5007/1983-4535.2011v4n2p110   O mercado educacional vive momentos de intensas transformações, principalmente em razão da grande concorrência do setor. O presente artigo tem por objetivo fazer uma análise geral desse mercado, evidenciando a ótica do marketing, sua importância e a necessidade de adaptação à nova economia e suas exigências. Para tal, utilizamos a metodologia da pesquisa bibliográfica e documental. Os resultados apontam para a necessidade de ações estratégicas de marketing, visando ao fortalecimento das Instituições de Ensino Superior – IES na acirrada concorrência existente no setor. Percebemos que, até a bem pouco tempo, grande parte das IES focava seus investimentos em prédios e laboratórios, sem a devida preocupação de identificar as expectativas e desejos dos alunos e as exigências do mercado. Concluímos que a nova realidade exige, hoje, um posicionamento transparente e que a reputação da marca e os valores a ela agregados ganham cada vez mais importância, o que implica no desenvolvimento de ações internas e externas, dentro de uma óptica que classifica o aluno como cliente, não apenas como estudante

ATUAÇÃO DO DEPARTAMENTO DE MARKETING EM UMA INSTITUIÇÃO DE ENSINO SUPERIOR - IES

The education market has been experiencing moments of intense changes, mainly due to the fierce competition in the industry. This article aims to make a general analysis of this market, showing the perspective of marketing, its importance and the need to adapt to the new economy and its requirements. For such purpose, we use the methodology of documentary and bibliographical research. The results indicate the need of strategic marketing actions, which aims to strengthen higher education institutions - HEIs in the fierce competition in the sector. We realize that until very recently, most of the HEIs focused their investments in buildings and laboratories, without due concern to identify the expectations and desires of students and the demands of the market. We conclude that, nowadays, the new reality requires clear positioning and that the brand reputation and value added to it are becoming increasingly important, which implies the development of internal and external actions, within a perspective that classifies the student as a client, not just as a student

The use of mobile devices in the college classroom: project method and mobile technologies in higher education

This study reports partial results from the research entitled "Project Method and Mobile Technologies: Potentialities and Challenges to the Teaching and Learning Processes in Marketing Undergraduation Course", developed within the Graduate Program in Education of the Universidade do Oeste Paulista (UNOESTE/Presidente Prudente/SP/Brazil). This research has adopted as general objective to analyze how mobile technologies can be articulated to the development of work projects, aiming at their integration to the pedagogical practices in higher education. The research was based on the qualitative approach and was carried out in the form of intervention research. Data were collected through participant observation, semi-structured interview, questionnaire and focus group. As context, we adopted the reality of the Marketing Undergradtion Course, offered by a private higher education institution (HEI) from, located in the city of Lins/SP/Brazil. The results obtained provided an understanding of the profile of higher education students in the contemporary era and the need for (re)construction of pedagogical practices to these students. The importance of work projects as an opportunity to adopt an active methodology articulated to mobile technologies in higher education was also evidenced

The use of mobile devices in the college classroom: project method and mobile technologies in higher education

This study reports partial results from the research entitled "Project Method and Mobile Technologies: Potentialities and Challenges to the Teaching and Learning Processes in Marketing Undergraduation Course", developed within the Graduate Program in Education of the Universidade do Oeste Paulista (UNOESTE/Presidente Prudente/SP/Brazil). This research has adopted as general objective to analyze how mobile technologies can be articulated to the development of work projects, aiming at their integration to the pedagogical practices in higher education. The research was based on the qualitative approach and was carried out in the form of intervention research. Data were collected through participant observation, semi-structured interview, questionnaire and focus group. As context, we adopted the reality of the Marketing Undergradtion Course, offered by a private higher education institution (HEI) from, located in the city of Lins/SP/Brazil. The results obtained provided an understanding of the profile of higher education students in the contemporary era and the need for (re)construction of pedagogical practices to these students. The importance of work projects as an opportunity to adopt an active methodology articulated to mobile technologies in higher education was also evidenced.O presente estudo relata resultados parciais da pesquisa intitulada “Pedagogia de Projetos e as Tecnologias Móveis: Potencialidades e Desafios aos Processos de Ensino e de Aprendizagem no Curso Superior de Marketing”, desenvolvida no âmbito do Programa de Pós-Graduação em Educação na Universidade do Oeste Paulista (UNOESTE/Presidente Prudente/SP/Brasil). Esta investigação adotou como objetivo geral analisar como as tecnologias móveis podem ser articuladas ao desenvolvimento de projetos de trabalho, visando à sua integração às práticas pedagógicas no ensino superior. A investigação se desenvolveu embasada na abordagem qualitativa e foi realizada sob a forma de pesquisa-intervenção. Os dados foram coletados por meio da observação participante, entrevista semiestruturada, questionário e grupo focal. Como contexto, adotou-se a realidade do curso superior de Marketing, ofertado por uma IES da rede privada, situada no município de Lins/SP/Brasil. Os resultados alcançados propiciaram a compreensão do perfil dos estudantes de ensino superior na era contemporânea e a necessidade de (re)construção das práticas pedagógicas diante desse alunado. Evidenciou-se ainda a importância dos projetos de trabalho como uma oportunidade de adotar uma metodologia ativa articulada às tecnologias móveis no ensino superior.El presente estudio relata resultados parciales de la investigación titulada "Pedagogía de Proyectos y las Tecnologías Móviles: Potencialidades y Desafíos a los Procesos de Enseñanza y de Aprendizaje en el Curso Superior de Marketing", desarrollada en el ámbito del Programa de Postgrado en Educación en la Universidad del Oeste Paulista (UNOESTE/Presidente Prudente/SP/Brasil). Esta investigación adoptó como objetivo general analizar cómo las tecnologías móviles pueden ser articuladas al desarrollo de proyectos de trabajo, buscando su integración a las prácticas pedagógicas en la enseñanza superior. La investigación se desarrolló basadas en el enfoque cualitativo y se llevó a cabo en forma de investigación-intervención. Los datos fueron recolectados por medio de la observación participante, entrevista semiestructurada, cuestionario y grupo focal. Como contexto, se adoptó la realidad del curso superior de Marketing, ofrecido por una IES de la red privada, situada en el municipio de Lins/SP/Brasil. Los resultados alcanzados propiciaron la comprensión del perfil de los estudiantes de enseñanza superior en la era contemporánea y la necesidad de (re) construcción de las prácticas pedagógicas ante ese alunado. Se evidenció la importancia de los proyectos de trabajo como una oportunidad de adoptar una metodología activa articulada a las tecnologías móviles en la enseñanza superior.

Numbers of ORFs identified in <i>A. deanei</i> and <i>S. culicis</i> and their symbionts, according to the mechanisms of DNA replication and repair, signal transduction, transcription and translation.

<p>Numbers of ORFs identified in <i>A. deanei</i> and <i>S. culicis</i> and their symbionts, according to the mechanisms of DNA replication and repair, signal transduction, transcription and translation.</p