The miniJPAS survey: Identification and characterization of galaxy populations with the J-PAS photometric system

Full list of authors: González Delgado, R. M.; Díaz-García, L. A.; de Amorim, A.; Bruzual, G.; Cid Fernandes, R.; Pérez, E.; Bonoli, S.; Cenarro, A. J.; Coelho, P. R. T.; Cortesi, A.; García-Benito, R.; López Fernández, R.; Martínez-Solaeche, G.; Rodríguez-Martín, J. E.; Magris, G.; Mejía-Narvaez, A.; Brito-Silva, D.; Abramo, L. R.; Diego, J. M. ; Dupke, R. A.; Hernán-Caballero, A.; Hernández-Monteagudo, C.; López-Sanjuan, C.; Marín-Franch, A.; Marra, V.; Moles, M.; Montero-Dorta, A.; Queiroz, C.; Sodré, L.; Varela, J.; Vázquez Ramió, H.; Vílchez, J. M.; Baqui, P. O.; Benítez, N.; Cristóbal-Hornillos, D.; Ederoclite, A.; Mendes de Oliveira, C.; Civera, T.; Muniesa, D.; Taylor, K.; Tempel, E.; J-PAS Collaboration.The Javalambre-Physics of the Accelerating Universe Astrophysical Survey (J-PAS) will soon start imaging thousands of square degrees of the northern sky with its unique set of 56 filters (spectral resolution of R - 60). Before the arrival of the final instrument, we observed 1 deg2 on the AEGIS field with an interim camera with all the J-PAS filters. Taking advantage of these data, dubbed miniJPAS, we aim at proving the scientific potential of the J-PAS to derive the stellar population properties of galaxies via fitting codes for spectral energy distributions (SEDs), with the ultimate goal of performing galaxy evolution studies across cosmic time. One parametric (BaySeAGal) and three non-parametric (MUFFIT, AlStar, and TGASPEX) SED-fitting codes are used to constrain the stellar mass, age, metallicity, extinction, and rest-frame and dust-corrected (u-r) colours of a complete flux-limited sample (rSDSS - 22.5 AB) of miniJPAS galaxies that extends up to z = 1. We generally find consistent results on the galaxy properties derived from the different codes, independently of the galaxy spectral type or redshift; this is remarkable considering that 25% of the J-spectra have signal-to-noise ratios (S/N) -3. For galaxies with S=N - 10, we estimate that the J-PAS photometric system will allow us to derive the stellar population properties of rest-frame (u - r) colour, stellar mass, extinction, and mass-weighted age with a precision of 0:04 - 0:02 mag, 0:07 - 0:03 dex, 0:2 - 0:09 mag, and 0:16 - 0:07 dex, respectively. This precision is equivalent to that obtained with spectroscopic surveys of similar S/N. By using the dust-corrected (u - r) colour mass diagram, a powerful proxy for characterizing galaxy populations, we find: (i) that the fraction of red and blue galaxies evolves with cosmic time, with red galaxies being -38% and -18% of the whole population at z = 0:1 and z = 0:5, respectively, and (ii) consistent results between codes for the average intrinsic (u-r) colour, stellar mass, age, and stellar metallicity of blue and red galaxies and their evolution up to z = 1. At all redshifts, the more massive galaxies belong to the red sequence, and these galaxies are typically older and more metal-rich than their counterparts in the blue cloud. Our results confirm that with J-PAS data we will be able to analyse large samples of galaxies up to z - 1, with galaxy stellar masses above log(M?=M-) - 8:9, 9.5, and 9.9 at z = 0:3, 0.5, and 0.7, respectively. The star formation history of a complete sub-sample of galaxies selected at z - 0:1 with log(M=M-) > 8:3 constrains the cosmic evolution of the star formation rate density up to z - 3, in good agreement with results from cosmological surveys. © ESO 2021.Acknowledgements. R.G.D., L.A.D.G., R.G.B., G.M.S., J.R.M., and E.P. acknowledge financial support from the State Agency for Research of the Spanish MCIU through the “Center of Excellence Severo Ochoa” award to the Instituto de Astrofísica de Andalucía (SEV-2017-0709), and to the AYA2016-77846-P and PID2019-109067-GB100. L.A.D.G. also acknowledges financial support by the Ministry of Science and Technology of Taiwan (grant MOST 106-2628-M-001-003-MY3) and by the Academia Sinica (grant AS-IA-107-M01). G.B. acknowledges financial support from the National Autonomous University of México (UNAM) through grant DGAPA/PAPIIT IG100319 and from CONACyT through grant CB2015-252364. SB acknowledges PGC2018-097585-B-C22, MINECO/FEDER, UE of the Spanish Ministerio de Econo-mia, Industria y Competitividad. L.S.J. acknowledges support from Brazilian agencies FAPESP (2019/10923-5) and CNPq (304819/201794). P.O.B. acknowledges support from the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES) – Finance Code 001. P.R.T.C. acknowledges financial support from Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) process number 2018/05392-8 and Conselho Nacional de Desenvolvi-mento Científico e Tecnológico (CNPq) process number 310041/2018-0. V.M. thanks CNPq (Brazil) for partial financial support. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 888258. E.T. acknowledges support by ETAg grant PRG1006 and by EU through the ERDF CoE grant TK133. Based on observations made with the JST/T250 telescope and PathFinder camera for the miniJPAS project at the Observatorio Astrofísico de Javalambre (OAJ), in Teruel, owned, managed, and operated by the Centro de Estudios de Física del Cosmos de Aragón (CEFCA). We acknowledge the OAJ Data Processing and Archiving Unit (UPAD) for reducing and calibrating the OAJ data used in this work. Funding for OAJ, UPAD, and CEFCA has been provided by the Governments of Spain and Aragón through the Fondo de Inver-siones de Teruel; the Aragón Government through the Research Groups E96, E103, and E16_17R; the Spanish Ministry of Science, Innovation and Universities (MCIU/AEI/FEDER, UE) with grant PGC2018-097585-B-C21; the Spanish Ministry of Economy and Competitiveness (MINECO/FEDER, UE) under AYA2015-66211-C2-1-P, AYA2015-66211-C2-2, AYA2012-30789, and ICTS-2009-14; and European FEDER funding (FCDD10-4E-867, FCDD13-4E-2685).Peer reviewe

Adjuvant dabrafenib and trametinib for patients with resected BRAF-mutated melanoma: DESCRIBE-AD real-world retrospective observational study

BRAF and MEK inhibitor, dabrafenib plus trametinib, adjuvant therapy is effective for high-risk resected melanoma patients with BRAF-V600 mutations. However, real-world evidence is limited. We aimed to determine the feasibility of this therapy in routine clinical practice. DESCRIBE-AD, a retrospective observational study, collected real-world data from 25 hospitals in Spain. Histologically confirmed and resected BRAF-mutated melanoma patients aged & GE;18 years who were previously treated with dabrafenib plus trametinib adjuvant therapy, were included. The primary objectives were treatment discontinuation rate and time to discontinuation. The secondary objectives included safety and efficacy. From October 2020 to March 2021, 65 patients were included. Dabrafenib and trametinib discontinuation rate due to treatment-related adverse events (TRAEs) of any grade was 9%. Other reasons for discontinuation included patients' decisions (6%), physician decisions (6%), unrelated adverse events (3%), disease progression (5%), and others (5%). The median time to treatment discontinuation was 9 months [95% confidence interval (CI), 5-11]. G3-4 TRAEs occurred in 21.5% of patients, the most common being pyrexia (3%), asthenia (3%), and diarrhoea (3%). Unscheduled hospitalisations and clinical tests occurred in 6 and 22% of patients, respectively. After 20-month median follow-up (95% CI, 18-22), 9% of patients had exitus due to disease progression, with a 12-month relapse-free survival and overall survival rates of 95.3% and 100%, respectively. Dabrafenib and trametinib adjuvant therapy proved effective for melanoma patients in a real-world setting, with a manageable toxicity profile. Toxicity frequencies were low leading to low incidence of unscheduled medical visits, tests, and treatment discontinuations

Bestiarios. Silva de varia invención

157 páginas.Con el título Bestiarios se pretende aludir a toda esa genealogía que, a lo largo de su presencia en la Tierra, el ser humano ha concebido como un extremo de lo que él mismo es: la bestia que medra en su sino más íntimo. David Hume (apunte de Luis Villoro) afirmaba que todo acto de ficción partía, necesariamente, de lo ya conocido por hombre o mujer, por mayor que fuera su extravagancia. Si imaginamos un cíclope, pongamos por caso, ese cíclope (más allá de las alegorías que pueda suscitarnos) tiene un ojo; y ese bestial ojo es algo que ya existe como ojo en la realidad. Los cuernos demoniacos son cuernos, así como sus patas de cabrío. La bestia es, pues, un extremo de la realidad conocida, y es en esos extremos donde se centran los autores del presente libro. Así pues, el libro cuenta con obras de la imaginación pictórica, la cual, conjuntada con la imaginación que provee el ensayo (especulación teórica y metódica) da como resultado un producto atractivo e interesante Un halago a la inteligencia abierta.Carlos Gómez Carro, coordinador; Guzo, ilustrador; Nicolás Amoroso y Maximino Javier, obra gráfica

Predictors of Response to Exclusive Enteral Nutrition in Newly Diagnosed Crohn´s Disease in Children: PRESENCE Study from SEGHNP

Exclusive enteral nutrition (EEN) has been shown to be more effective than corticosteroids in achieving mucosal healing in children with Crohn´s disease (CD) without the adverse effects of these drugs. The aims of this study were to determine the efficacy of EEN in terms of inducing clinical remission in children newly diagnosed with CD, to describe the predictive factors of response to EEN and the need for treatment with biological agents during the first 12 months of the disease. We conducted an observational retrospective multicentre study that included paediatric patients newly diagnosed with CD between 2014–2016 who underwent EEN. Two hundred and twenty-two patients (140 males) from 35 paediatric centres were included, with a mean age at diagnosis of 11.6 ± 2.5 years. The median EEN duration was 8 weeks (IQR 6.6–8.5), and 184 of the patients (83%) achieved clinical remission (weighted paediatric Crohn’s Disease activity index [wPCDAI] 15 mg/L and ileal involvement tended to respond better to EEN. EEN administered for 6–8 weeks is effective for inducing clinical remission. Due to the high response rate in our series, EEN should be used as the first-line therapy in luminal paediatric Crohn’s disease regardless of the location of disease and disease activityS

Guías colombianas de electrofisiología no invasiva

Los métodos diagnósticos no invasivos son el pilar inicial del estudio de cualquier paciente con una patología en particular, de ahí que sean los exámenes más solicitados y constituyan una importante carga en costos para un sistema de salud.Q4Guías1-12

The miniJPAS survey: A search for extreme emission-line galaxies

This is an Open Access article, published by EDP Sciences, under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Context. Galaxies with extreme emission lines (EELGs) may play a key role in the evolution of the Universe, as well as in our understanding of the star formation process itself. For this reason an accurate determination of their spatial density and fundamental properties in different epochs of the Universe will constitute a unique perspective towards a comprehensive picture of the interplay between star formation and mass assembly in galaxies. In addition to this, EELGs are also interesting in order to explain the reionization of the Universe, since their interstellar medium (ISM) could be leaking ionizing photons, and thus they could be low z, analogous of extreme galaxies at high z. Aims. This paper presents a method to obtain a census of EELGs over a large area of the sky by detecting galaxies with rest-frame equivalent widths ≥300 Å in the emission lines [O II]λλ3727,3729Å, [O III]λ5007Å, and Hα. For this, we aim to use the J-PAS survey, which will image an area of ≈8000 deg2 with 56 narrow band filters in the optical. As a pilot study, we present a methodology designed to select EELGs on the miniJPAS images, which use the same filter dataset as J-PAS, and thus will be exportable to this larger survey. Methods. We make use of the miniJPAS survey data, conceived as a proof of concept of J-PAS, and covering an area of ≈1 deg2. Objects were detected in the rSDSS images and selected by imposing a condition on the flux in a given narrow-band J-PAS filter with respect to the contiguous ones, which is analogous to requiring an observed equivalent width larger than 300 Å in a certain emission line within the filter bandwidth. The selected sources were then classified as galaxies or quasi-stellar objects (QSOs) after a comparison of their miniJPAS fluxes with those of a spectral database of objects known to present strong emission lines. This comparison also provided a redshift for each source, which turned out to be consistent with the spectroscopic redshifts when available (|Δz/(1 + zspec)| ≤ 0.01). Results. The selected candidates were found to show a compact appearance in the optical images, some of them even being classified as point-like sources according to their stellarity index. After discarding sources classified as QSOs, a total of 17 sources turned out to exhibit EW0 ≥ 300 Å in at least one emission line, thus constituting our final list of EELGs. Our counts are fairly consistent with those of other samples of EELGs in the literature, although there are some differences, which were expected due to biases resulting from different selection criteria. © J. Iglesias-Páramo et al. 2022.This work has been partially funded by projects PID2019-107408GB-C44 from the Spanish PNAYA, co-funded with FEDER, and grand P18-FR-2664, funded by Junta de Andalucía. We acknowledge financial support from the State Agency for Research of the Spanish MCIU through the “Center of Excellence Severo Ochoa” award to the Instituto de Astrofísica de Andalucía (SEV-2017-0709). RGD and LADG acknowledge financial support from the State Agency for Research of the Spanish MCIU through the “Center of Excellence Severo Ochoa” award to the Instituto de Astrofísica de Andalucía (SEV-2017-0709), and PID2019-109067-GB100. IM acknowledges financial support from the State Agency for Research of the Spanish MCIU through the PID2019-106027GB-C41. JCM acknowledges partial support from the Spanish Ministry of Science, Innovation and Universities (MCIU/AEI/FEDER, UE) through the grant PGC2018-097585-B-C22. SDP is grateful to the Fonds de Recherche du Québec – Nature et Technologies. LSJ acknowledges the support of CNPq (304819/2017-4) and FAPESP (2019/10923-5). JAFO acknowledges the financial support from the Spanish Ministry of Science and Innovation and the European Union – NextGenerationEU through the Recovery and Resilience Facility project ICTS-MRR-2021-03- CEFCA. Funding for the J-PAS Project has been provided by the Governments of España and Aragón though the Fondo de Inversión de Teruel, European FEDER funding and the MINECO and by the Brazilian agencies FINEP, FAPESP, FAPERJ and by the National Observatory of Brazil. Based on observations made with the JST/T250 telescope and PathFinder camera for the miniJPAS project at the Observatorio Astrofísico de Javalambre (OAJ), in Teruel, owned, managed, and operated by the Centro de Estudios de Física del Cosmos de Aragón (CEFCA). We acknowledge the OAJ Data Processing and Archiving Unit (UPAD) for reducing and calibrating the OAJ data used in this work. Funding for OAJ, UPAD, and CEFCA has been provided by the Governments of Spain and Aragón through the Fondo de Inversiones de Teruel; the Aragón Government through the Research Groups E96, E103, and E16_17R; the Spanish Ministry of Science, Innovation and Universities (MCIU/AEI/FEDER, UE) with grant PGC2018-097585-B-C21; the Spanish Ministry of Economy and Competitiveness (MINECO/FEDER, UE) under AYA2015-66211-C2-1-P, AYA2015-66211-C2-2, AYA2012-30789, and ICTS-2009-14; and European FEDER funding (FCDD10-4E-867, FCDD13-4E-2685). This research has made use of the NASA/IPAC Extragalactic Database (NED), which is operated by the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics and Space Administration. Funding for SDSS-IV has been provided by the Alfred P. Sloan Foundation, the Participating Institutions, the National Science Foundation, and the U.S. Department of Energy Office of Science. The SDSS-IV web site is https://www.sdss.org/. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 898633.Peer reviewe

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Comparação do desenvolvimento inicial de quatro espécies na restauração florestal parcelas com três sistemas diferentes de preparação do solo no departamento de Caazapa, Paraguai

As a result of the advance of the agro-livestock frontier, the Alto Paraná ecoregion has lost more than 90% of its original surface, currently leaving only isolated remnants of this ecosystem. Thus, this ecoregion’s restoration efforts and their success are key to the conservation of the biodiversity that it harbors. In this context, the objective of this work was to know the initial development of Campomanesia xanthocarpa, Cordia americana, Cordia trichotoma and Melia azedarach under three land preparation systems in a restoration project: i) manual drilling, ii) controlled burning + manual drilling and iii) conventional land preparation; in four plots in the Golondrina farm, Caazapá. The data collected were (a) diameter at neck height (DNH), (b) height, and (c) number of branches. For data analysis, ANOVA and the Tukey-Kramer testwere performed. Cordia americana was the species with the best development in the three variables studied in the three soil preparation systems, while Campomanesia xanthocarpa had the lowest development among the four species studied. Cordia trichotoma was the second best-developing species followed by Melia azedarach, which was affected by frost.Como resultado del avance de la frontera agropecuaria, la ecorregión Alto Paraná ha perdido más del 90% de su superficie original, dejando en la actualidad solo remanentes aislados de este ecosistema. Por lo tanto, los esfuerzos de restauración de esta ecorregión y su éxito son clave para la conservación de la biodiversidad que alberga. En este contexto, el objetivo de este trabajo fue conocer el desarrollo inicial de Campomanesia xanthocarpa, Cordia americana, Cordia trichotoma y Melia azedarach bajo tres sistemas de preparación del terreno en un proyecto de restauración: i) perforación manual, ii) quema controlada + perforación manual y iii) preparación convencional de la tierra; en cuatro parcelas de la finca Golondrina, Caazapá. Los datos recolectados fueron (a) diámetro a la altura del cuello (DAC), (b) altura y (c) número de ramas. Para el análisis de los datos se realizaron ANOVA y la prueba de Tukey-Kramer. Cordia americana fue la especie con mejor desarrollo en las tres variables estudiadas en los tres sistemas de preparación del suelo, mientras que Campomanesia xanthocarpa tuvo el menor desarrollo entre las cuatro especies estudiadas. Cordia trichotoma fue la segunda especie de mejor desarrollo seguida de Melia azedarach, que se vio afectada por las heladas.Como resultado do avanço da fronteira agro-pecuária, a ecorregião de Alto Paraná perdeu mais do que 90% de sua superfície original, deixando atualmente apenas restos isolados deste ecossistema. Assim, os esforços de restauração desta ecorregião e seu sucesso são a chave para a conservação do biodiversidade que ela abriga. Neste contexto, o objetivo deste trabalho era conhecer a desenvolvimento da Campomanesia xanthocarpa, Cordia americana, Cordia trichotoma e Melia azedarach sob três sistemas de preparação do terreno em um projeto de restauração: i) perfuração manual, ii) queima controlada + perfuração manual e iii) preparação convencional do terreno; em quatro parcelas em a fazenda Golondrina, Caazapá. Os dados coletados foram (a) diâmetro à altura do pescoço (DNH), (b) altura, e (c) número de ramificações. Para análise de dados, ANOVA e o teste Tukey-Kramer foram realizadas. A Cordia americana foi a espécie com melhor desenvolvimento nos três variáveis estudadas nos três sistemas de preparação do solo, enquanto a Campomanesia xanthocarpa teve o menor desenvolvimento entre as quatro espécies estudadas. Cordia trichotoma foi o segunda melhor espécie em desenvolvimento seguida pela Melia azedarach, que foi afetada pela geada

Evaluación del tripolifosfato de sodio como anticoagulante en determinaciones hematológicas en seres humanos Assessment of anticoagulant sodium tripolyphosphate used in hematologic determinations in human being

El propósito del presente estudio fue evaluar la utilidad del tripolifosfato de sodio (TPF) como anticoagulante en diferentes determinaciones hematológicas en seres humanos. Muestras de sangre venosa procedentes de adultos sanos de ambos sexos fueron anticoaguladas con TPF, sales dipotásicas del ácido etilendiaminotetraacético (EDTA) y citrato de sodio. Las muestras anticoaguladas con EDTA y citrato de sodio fueron utilizadas como controles. Al comparar los valores obtenidos en todas las pruebas realizadas se encontró que la sangre anticoagulada con TPF ofreció resultados similares a las tratadas con los anticoagulantes usados como controles. Los resultados muestran que es posible la utilización del TPF para la determinación de los parámetros de hematología completa y tiempos de coagulación, permitiendo el uso de una sola muestra con menos volumen sanguíneo, lo cual resultaría beneficioso para los pacientes en quienes la extracción de importantes volúmenes de sangre es en ocasiones difícil y molesta.The aim of present study was to assess the usefulness of anticoagulant sodium tripolyphosphate (TPP) in different hematologic determinations in human beings. Venous blood samples from healthy adults of both sexes were anticoagulated with TPP, dipotassium salts of ethylenediaminetetra-acetic acid (EDTA) and sodium citrate. Anticoagulated samples with EDTA and sodium citrate were used as controls. Verifying the values achieved in all tests performed we noted that anticoagulated blood with TPP offered results similar to those treated with anticoagulant used as controls. Results show that it is possible the use of TPP to determine the parameters of total hematology and coagulation times, allowing the use of only one sample with less blood volume, which could be beneficial for patients in which blood collection in significant volumes in occasions is difficult and annoying

Albert Einstein : un siglo del la Teoría de la Relatividad especial

Sumario : Einstein, una estrella...¿binaria?.-- Cuásares y chorros relativistas.-- Lentes gravitatorias.-- Ondas gravitatorias: dinámica del espacio-tiempo.-- La irresistible tentación cosmológica de la Relatividad General.-- Más allá de la relatividad.-- Mecánica cuántica y gravitación.Esta revista se publica con la ayuda de la Accion Especial DIF 2003-10261-E del Programa Nacional de Difusión de la Ciencia y la Tecnología, del Ministerio de Ciencia y Tecnología.N