Questions That Get Answered: The Construction of Instructional Conversations on Online Asynchronous Discussion Boards

Abstract On online asynchronous discussion boards, instructor questions are considered a driving force in student engagement and learning. Yet, students can and do choose not to answer questions from instructors. In this paper, the authors report on a qualitative study in which they analyzed instructor-student interaction on an asynchronous discussion board in order to determine which instructor's questions students were more likely to answer and why. They found that students were more likely to answer those instructor questions that were authentic and exhibited uptake of students' comments. Moreover, the students' orientation to those features suggests that students actively choose to engage in -and construct -coherent instructional interactions that characterize conversation rather than recitation

Design and characterization of the POLARBEAR-2b and POLARBEAR-2c cosmic microwave background cryogenic receivers

The POLARBEAR-2/Simons Array Cosmic Microwave Background (CMB) polarization experiment is an upgrade and expansion of the existing POLARBEAR-1 (PB-1) experiment, located in the Atacama desert in Chile. Along with the CMB temperature and $E$-mode polarization anisotropies, PB-1 and the Simons Array study the CMB $B$-mode polarization anisotropies produced at large angular scales by inflationary gravitational waves, and at small angular scales by gravitational lensing. These measurements provide constraints on various cosmological and particle physics parameters, such as the tensor-to-scalar ratio $r$, and the sum of the neutrino masses. The Simons Array consists of three 3.5 m diameter telescopes with upgraded POLARBEAR-2 (PB-2) cryogenic receivers, named PB-2a, -2b, and -2c. PB-2a and -2b will observe the CMB over multiple bands centered at 95 GHz and 150 GHz, while PB-2c will observe at 220 GHz and 270 GHz, which will enable enhanced foreground separation and de-lensing. Each Simons Array receiver consists of two cryostats which share the same vacuum space: an optics tube containing the cold reimaging lenses and Lyot stop, infrared-blocking filters, and cryogenic half-wave plate; and a backend which contains the focal plane detector array, cold readout components, and millikelvin refrigerator. Each PB-2 focal plane array is comprised of 7,588 dual-polarization, multi-chroic, lenslet- and antenna-coupled, Transition Edge Sensor (TES) bolometers which are cooled to 250 mK and read out using Superconducting Quantum Interference Devices (SQUIDs) through a digital frequency division multiplexing scheme with a multiplexing factor of 40. In this work we describe progress towards commissioning the PB-2b and -2c receivers including cryogenic design, characterization, and performance of both the PB-2b and -2c backend cryostats.Comment: 20 page

Cisplatin administration influences on toxic and non-essential element metabolism in rats

Nowadays several papers deal with the effectiveness and side effects of metal complexes, especially cisplatin, in cancer therapy. The excretion of essential metal elements from the body is a serious problem in the treatment, but there are no data concerning the distribution and metabolism of toxic and nonessential elements. Therefore our aim was to study the concentration of some of these elements after treatment with cisplatin. Male Wistar rats (n=20, 175-190 g) were randomly divided into 2 groups (n=10/group). The control group received 1% (w/v) methyl cellulose at 10 mL/kg body weight, p.o. by gastric gavage twice daily for 14 days, while cisplatin was injected i.p. in a single dose of 6.5 mg/kg body weight. Inductively coupled plasma optical emission spectrometry (ICP-OES) was used for measuring Al, B, Ba, Cr, Li, Ni, Pb, Pt, Sb, Si, Sn, Sr and V content in plasma, liver and kidney. Liver total scavenger capacity, diene conjugate content and malondialdehyde concentration were also determined. Cisplatin elevated the free radical reactions in the liver, although redox balance did not change significantly. According to the study it seems that the metabolism of Al, Ba, Cr, Ni, Pb, Sr were changed by the effect of cisplatin, and the most notable alterations were found for Al and Pb. Therefore, besides the toxic effect of and free radical induction by Pt, the side effects of increased levels of other toxic and non-essential elements have to be taken into consideration

Effects of some analgesics and antidepressants on the (Na+ + K + )-adenosine triphosphatase from cortices of brain and kidney

The effects of benzomorphans, tricyclic antidepressants, monoamine oxidase (MAO) inhibitors and chlorpromazine on the microsomal (Na+ + K+)-adenosine triphosphatase (ATPase) from beef cerebral cortex were studied. As a comparison, the interaction of these drugs with the corresponding enzyme from kidney cortex was also investigated. In addition to chlorpromazine, the benzomorphans and the tricyclic antidepressants inhibited the brain enzyme considerably, whereas the MAO inhibitors had little effect. The (Na+ + K+)-ATPase from kidney was not affected by the benzomorphans or MAO inhibitors, but its activity diminished in the presence of the tricyclic antidepressants and chlorpromazine.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/34064/1/0000342.pd

An integrated approach to coastal erosion problems in northern Tuscany (Italy): Littoral morphological evolution and cell distribution

Occupation of the coast has significantly increased in recent decades, mostly due to a greater demand for recreation and tourism. Today, erosion threatens many human-made structures and activities, requiring an integrated approach for the understanding of coastal dynamics and identification of alternatives to associated problems. This study investigates a 64 km-long coastal physiographic unit in the northern microtidal littoral of Tuscany (Italy). Vertical aerial photographs and direct field surveys were used to retrieve changes in shoreline position over 1938–1997 and 1997–2005 time intervals. Significant beach accretion was observed during the first period updrift of Carrara (84 m) and Viareggio (280 m) harbours and at Marina di Pietrasanta (100 m), whereas severe erosion occurred downcoast of Carrara harbour (−130 m, at Marina dei Ronchi) and on the northern side of Arno river mouth (−400 m). Similar trends were observed between 1997 and 2005; beach slope between the 1997 shoreline position and the closure depth correlated well with the distribution of erosion/accretion patterns from the 1938–1997 period (slopes were lower in eroded areas than at sites under accretion). Longshore distribution of erosion/accretion patterns was controlled by coastal compartmentalisation. Three of the main littoral cells were mostly formed by natural limits (i.e., Punta Bianca promontory, Marina di Pietrasanta, the Arno river mouth and the port of Livorno). Several sub-cells were created within these cells due to the introduction of human-made structures (such as Carrara and Viareggio harbours), which formed artificial fixed limits that allowed the transport of sediments (exclusively fines) in one direction only. Results will help improve the understanding of coastal processes and manage littoral sediment transport in a sustainable manner. This will reduce the need for structural interventions, such as breakwaters and groynes, which in the past decades prevented coastal retreat at local scale but shifted erosion downdrift, leading to degradation of the investigated area and requiring continuous maintenance

Gravitational Waves From Known Pulsars: Results From The Initial Detector Era

We present the results of searches for gravitational waves from a large selection of pulsars using data from the most recent science runs (S6, VSR2 and VSR4) of the initial generation of interferometric gravitational wave detectors LIGO (Laser Interferometric Gravitational-wave Observatory) and Virgo. We do not see evidence for gravitational wave emission from any of the targeted sources but produce upper limits on the emission amplitude. We highlight the results from seven young pulsars with large spin-down luminosities. We reach within a factor of five of the canonical spin-down limit for all seven of these, whilst for the Crab and Vela pulsars we further surpass their spin-down limits. We present new or updated limits for 172 other pulsars (including both young and millisecond pulsars). Now that the detectors are undergoing major upgrades, and, for completeness, we bring together all of the most up-to-date results from all pulsars searched for during the operations of the first-generation LIGO, Virgo and GEO600 detectors. This gives a total of 195 pulsars including the most recent results described in this paper.United States National Science FoundationScience and Technology Facilities Council of the United KingdomMax-Planck-SocietyState of Niedersachsen/GermanyAustralian Research CouncilInternational Science Linkages program of the Commonwealth of AustraliaCouncil of Scientific and Industrial Research of IndiaIstituto Nazionale di Fisica Nucleare of ItalySpanish Ministerio de Economia y CompetitividadConselleria d'Economia Hisenda i Innovacio of the Govern de les Illes BalearsNetherlands Organisation for Scientific ResearchPolish Ministry of Science and Higher EducationFOCUS Programme of Foundation for Polish ScienceRoyal SocietyScottish Funding CouncilScottish Universities Physics AllianceNational Aeronautics and Space AdministrationOTKA of HungaryLyon Institute of Origins (LIO)National Research Foundation of KoreaIndustry CanadaProvince of Ontario through the Ministry of Economic Development and InnovationNational Science and Engineering Research Council CanadaCarnegie TrustLeverhulme TrustDavid and Lucile Packard FoundationResearch CorporationAlfred P. Sloan FoundationAstronom

Measurements of tropospheric ice clouds with a ground-based CMB polarization experiment, POLARBEAR

The polarization of the atmosphere has been a long-standing concern for ground-based experiments targeting cosmic microwave background (CMB) polarization. Ice crystals in upper tropospheric clouds scatter thermal radiation from the ground and produce a horizontally polarized signal. We report a detailed analysis of the cloud signal using a ground-based CMB experiment, Polarbear, located at the Atacama desert in Chile and observing at 150 GHz. We observe horizontally polarized temporal increases of low-frequency fluctuations ("polarized bursts," hereafter) of 720.1 K when clouds appear in a webcam monitoring the telescope and the sky. The hypothesis of no correlation between polarized bursts and clouds is rejected with >24\u3c3 statistical significance using three years of data. We consider many other possibilities including instrumental and environmental effects, and find no reasons other than clouds that can explain the data better. We also discuss the impact of the cloud polarization on future ground-based CMB polarization experiments

The POLARBEAR-2 and Simons Array Focal Plane Fabrication Status

We present on the status of POLARBEAR-2 A (PB2-A) focal plane fabrication. The PB2-A is the first of three telescopes in the Simon Array (SA), which is an array of three cosmic microwave background (CMB) polarization sensitive telescopes located at the POLARBEAR (PB) site in Northern Chile. As the successor to the PB experiment, each telescope and receiver combination is named as PB2-A, PB2-B, and PB2-C. PB2-A and -B will have nearly identical receivers operating at 90 and 150 GHz while PB2-C will house a receiver operating at 220 and 270 GHz. Each receiver contains a focal plane consisting of seven close-hex packed lenslet coupled sinuous antenna transition edge sensor bolometer arrays. Each array contains 271 di-chroic optical pixels each of which have four TES bolometers for a total of 7588 detectors per receiver. We have produced a set of two types of candidate arrays for PB2-A. The first we call Version 11 (V11) and uses a silicon oxide (SiOx) for the transmission lines and cross-over process for orthogonal polarizations. The second we call Version 13 (V13) and uses silicon nitride (SiNx) for the transmission lines and cross-under process for orthogonal polarizations. We have produced enough of each type of array to fully populate the focal plane of the PB2-A receiver. The average wirebond yield for V11 and V13 arrays is 93.2% and 95.6% respectively. The V11 arrays had a superconducting transition temperature (Tc) of 452 +/- 15 mK, a normal resistance (Rn) of 1.25 +/- 0.20 Ohms, and saturations powers of 5.2 +/- 1.0 pW and 13 +/- 1.2 pW for the 90 and 150 GHz bands respectively. The V13 arrays had a superconducting transition temperature (Tc) of 456 +/-6 mK, a normal resistance (Rn) of 1.1 +/- 0.2 Ohms, and saturations powers of 10.8 +/- 1.8 pW and 22.9 +/- 2.6 pW for the 90 and 150 GHz bands respectively

Momentum sharing in imbalanced Fermi systems

The atomic nucleus is composed of two different kinds of fermions, protons and neutrons. If the protons and neutrons did not interact, the Pauli exclusion principle would force the majority fermions (usually neutrons) to have a higher average momentum. Our high-energy electron scattering measurements using 12C, 27Al, 56Fe and 208Pb targets show that, even in heavy neutron-rich nuclei, short-range interactions between the fermions form correlated high-momentum neutron-proton pairs. Thus, in neutron-rich nuclei, protons have a greater probability than neutrons to have momentum greater than the Fermi momentum. This finding has implications ranging from nuclear few body systems to neutron stars and may also be observable experimentally in two-spin state, ultra-cold atomic gas systems.Comment: Published in Science. 10 pages, 3 figure