Estudio baropodométrico en pacientes tratados mediante artroplastia total de rodilla

La patología artrósica de la rodilla condiciona una disminución de la carga del miembro afecto y un patrón de apoyo con predominio generalmente del arco externo. El propósito de este estudio es determinar si existe una modificación significativa de este patrón tras la implantación de una artroplastia total de rodilla (ATR) primaria, recogiendo las presiones plantares de ambos pies mediante baropodometría electrónica previamente y 4 meses tras la cirugía, tanto en estática como en dinámica. Así, se analizan las presiones plantares de 30 pacientes, 21 mujeres y 9 hombres, intervenidos de ATR primaria en el Hospital Universitario Doctor Peset entre los años 2013 y 2015. También se ha determinado si existe una corrección del eje anatómico tras la cirugía. Utilizando test no paramétricos (test de Wilcoxon para datos apareados, U de Mann-Whitney), observamos una modificación significativa de dicho ángulo desde valores medianos de 1.2º de varo a 4.9º de valgo en el postoperatorio, una disminución mediana de la presión plantar en ambos pies y una redistribución de la carga axial, aumentando en el miembro intervenido. Concluimos que, 4 meses tras la cirugía, se produce una tendencia a la “normalización” de la pisada en pacientes en los que se ha implantado una ATR, condicionado tanto por la mejora del dolor y la funcionalidad como por la realineación del eje.Knee osteoarthritis determines a decrease of the load of the affected limb and a pattern usually dominance of external support plantar arc. The purpose of this study is to determine whether a significant change in this pattern is? after implantation of a primary total knee arthroplasty (TKA), measuring plantar pressures in both feet by electronic baropodometry previously and 4 months after surgery, in static and dynamic. Plantar pressures of 30 patients are analyzed, who underwent primary TKA at the University Hospital Doctor Peset between 2013 and 2015. In addition, it has also been determined if there is a correction on the anatomical axis after surgery. Using nonparametric test (Wilcoxon test for paired data, U Mann Whitney), we observed a significant change in the angle from median values of 1.2º varus to 4.9º valgus postoperatively, a median decrease of plantar pressure in both feet and a redistribution of axial load, increasing in the operated limb. We conclude that, 4 months after surgery, there is a tendency to “normalization” of the tread in patients undergoing TKA. This is conditioned by improving pain and function as axis realignment occurs

Evaluation of polyherbal methionine and choline in feedlot rations for lambs

Requirements of lambs for choline and methionine have not been clearly established, but because of their metabolic relationship, the availability of these two nutrients may affect protein synthesis and energy balance. Therefore, a trial was carried out to evaluate the effect on productive performance and blood metabolites of including methionine and choline from polyherbal mixtures in finishing lamb diets. Forty Hampshire x Suffolk lambs weighing 26.9 ± 2.8 kg were used for a 45-day experiment. The treatments were arranged as a 2x2 factorial, in which the factors were dietary supplementation with herbal methionine and choline at two levels (0% and 0.4% of dry matter (DM)). The treatments had no effects on the lambs’ productive variables (daily feed intake, average daily gain, and feed to gain ratio), carcass characteristics and lipid metabolites (P >0.05). The results indicated that the inclusion of polyherbal mixtures containing methionine, choline and their combination at 0.4% of DM in finishing lamb diets showed no benefits in productive response or in blood metabolites related to lipid metabolism. Keywords: amino acid, lipid metabolites, productive performance, ruminally protected, vitami

Development of an acoustic transceiver for the KM3NeT positioning system

[EN] In this paper we describe an acoustic transceiver developed for the KM3NeT positioning system. The acoustic transceiver is composed of a commercial free flooded transducer, which works mainly in the 20-40 kHz frequency range and withstands high pressures (up to 500 bars). A sound emission board was developed that is adapted to the characteristics of the transducer and meets all requirements: low power consumption, high intensity of emission, low intrinsic noise, arbitrary signals for emission and the capacity of acquiring the receiving signals with very good timing precision. The results of the different tests made with the transceiver in the laboratory and shallow sea water are described, as well as, the activities for its integration in the Instrumentation Line of the ANTARES neutrino telescope and in a NEMO tower for the in situ tests. © 2012 Elsevier B.V. All rights reserved.This work has been supported by the Ministerio de Ciencia e Innovacion (Spanish Government), Project references FPA2009-13983-C02-02, ACI2009-1067, AIC10-D-00583, and Consolider-Ingenio Multidark (CSD2009-00064). It has also been funded by Generalitat Valenciana, Prometeo/2009/26, and the European 7th Framework Programme, Grant no. 212525.Larosa, G.; Ardid Ramírez, M.; Llorens Alvarez, CD.; Bou Cabo, M.; Martínez Mora, JA.; Adrián Martínez, S.; KM3NeT Consortium (2013). Development of an acoustic transceiver for the KM3NeT positioning system. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 725:215-218. https://doi.org/10.1016/j.nima.2012.11.167S21521872

Reusing intravaginal progesterone releasing devices for oestrous synchoronization in ewes

In this study, the second use of an intravaginal progesterone-releasing device or controlled intravaginal drug release device (CIDR) was evaluated. After a first use of 11 days, the CIDR was again used for either nine or 12 days with 200 or 300 IU equine chorionic gonadotrophin (eCG) being injected on its removal. Sixty-four ewes were randomly distributed to four treatments (n=16/group): CIDR9+eCG200, CIDR9+eCG300, CIDR12+eCG200, and CIDR12+eCG300. The eCG was administered intramuscularly on withdrawal of the device. Thus, the experiment was a completely randomized design with a 2×2 factorial arrangement of treatments. Oestrus presentation did not differ between treatments (P =0.29). However, with the dose of 200 IU of eCG, oestrus presentation tended to increase (P =0.08). The onset and duration of oestrus, percentage of gestation, and return to oestrus did not differ between treatments (P >0.05). Progesterone concentration in serum was greater (P < 0.05) in ewes treated with CIDR12+eCG300. Prolificacy was greatest (1.44) with the CIDR12+eCG300 treatment and was different (P = 0.001) from the treatments CIDR9+eCG200 (1.21) and CIDR9+eCG300 (1.20), but not from the CIDR12+eCG200 treated ewes (1.31). The CIDR12+eCG300 treatement produced the highest percentage of twin births (45.8%) (P =0.001). Leaving the device in place for 12 days increased (P =0.001) the incidence of twin births. Use of the CIDR for a second time synchronized oestrus in ewes successfully with better fertility being obtained when the device was left in place for 12 days, and 300 IU of eCG was injected on its removal. Key words: gonadotropin, progesterone device, synchronizatio

Pyramidal core-shell quantum dot under applied electric and magnetic fields

We have theoretically investigated the electronic states in a core/shell pyramidal quantum dot with GaAs core embedded in AlGaAs matrix. This system has a quite similar recent experimental realization through a cone/shell structure [Phys. Status Solidi-RRL 13, 1800245 (2018)]. The research has been performed within the efective mass approximation taking into account position-dependent efective masses and the presence of external electric and magnetic felds. For the numerical solution of the resulting three-dimensional partial diferential equation we have used a fnite element method. A detailed study of the conduction band states wave functions and their associated energy levels is presented, with the analysis of the efect of the geometry and the external probes. The calculation of the non-permanent electric polarization via the of-diagonal intraband dipole moment matrix elements allows to consider the related optical response by evaluating the coefcients of light absorption and relative refractive index changes, under diferent applied magnetic feld confgurations

Ultrasonic transmitter for positioning of the large underwater neutrino telescope KM3NeT

This article belongs to a special issue: 43rd Annual UIA Symposium 23—25 April 2014 CSIC Madrid, Spain. Edited By Margaret Lucas and Enrique Riera[EN] Underwater ultrasonic transducers are commonly used for marine applications including communication and positioning systems. In this work, an ultrasonic transmitter transducer developed for the very large underwater neutrino telescope KM3NeT positioning is presented. The telescope infrastructure will have some degree of motion due to sea current; hence a positioning system is needed in order to monitor the position of the optical sensors. For this purpose, a reliable and affordable positioning based on acoustic systems is used. The ultrasound transmitter prototype developed as part of the positioning system is composed of a commercial FFR transducer and specifically designed electronics to optimize the system and fulfil the requirements of the KM3NeT infrastructure. The transmitter is able to generate high-power short signals with arbitrary waveform in a range of 20 kHz - 40 kHz and withstand high pressures. Signal processing techniques such as advanced cross-correlation methods and filtering as well as broad-band ultrasound signals are also applied for optimizing the acoustic emission and position detection. The work done for a precise laboratory testing and optimization of the system is described. The prototype has been integrated in the ANTARES neutrino telescope for testing its accuracy and the reach in situ. The test results obtained are also presented in this communication.This work has been supported by the Ministerio de Economía y Competitividad (Spanish Government), project ref. FPA2012-37528-C02-02, Multidark (CSD2009-00064) and the European 7th Framework Programme, Grant no. 212525.Saldaña Coscollar, M.; Adrián Martínez, S.; Bou Cabo, M.; Felis Enguix, I.; Larosa, G.; Llorens Alvarez, CD.; Martínez Mora, JA.... (2015). Ultrasonic transmitter for positioning of the large underwater neutrino telescope KM3NeT. Physics Procedia. 63:195-200. https://doi.org/10.1016/j.phpro.2015.03.032S1952006

Quality and quantity of organic fractions as affected by soil depth in an Argiudoll under Till and No-till systems

Aims: The aim of this study was to evaluate the long-term effect of tillage systems on the quantity and quality of organic carbon fractions at different soil layers. Study Design: The experimental design was a split plot with three blocks. The long-term effects (25 years) of conventional- (CT) and no-tillage (NT) systems on a Tipic Argiudoll was sampled at 0-5, 5-10, 10-15 and 15-20 cm soil depth. Place and Duration of Study: The field experiment was carried out at Tornquist (38° 07' 06'' S - 62°02' 17'' O) and soil sampling was performed during wheat seeding (June 2011). Methodology: Total soil organic carbon (SOC) content and the following fractions were determined: Coarse particulate (POCc, 105-2000 µm), fine particulate (POCf, 53-105 µm) and mineral-associated (MOC, 0-53 µm) carbon fractions; humic (HA) and fulvic (FA) acids; and total (CHt) and soluble (CHs) carbohydrates. The main physico-chemical properties of HA and FA were analyzed using both FT-IR and fluorescence spectroscopies. Results: After 25 years, total SOC at the 0-20 cm depth was 9% higher in no-tilled than in tilled soils. The POCf was the SOM fraction that turned out to be the most sensitive to tillage effects. The POCc:POCf:MOC ratio at 0-20 cm was similar for NT (3:14:82) and CT (5:10:84); however, differences were found across soil depths. Tilled soils showed higher aromaticity, starting by CH-degradation, in more superficial soil layers

Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics

Heteroplasmy, multiple variants of mitochondrial DNA (mtDNA) in the same cytoplasm, may be naturally generated by mutations but is counteracted by a genetic mtDNA bottleneck during oocyte development. Engineered heteroplasmic mice with nonpathological mtDNA variants reveal a nonrandom tissue-specific mtDNA segregation pattern, with few tissues that do not show segregation. The driving force for this dynamic complex pattern has remained unexplained for decades, challenging our understanding of this fundamental biological problem and hindering clinical planning for inherited diseases. Here, we demonstrate that the nonrandom mtDNA segregation is an intracellular process based on organelle selection. This cell type-specific decision arises jointly from the impact of mtDNA haplotypes on the oxidative phosphorylation (OXPHOS) system and the cell metabolic requirements and is strongly sensitive to the nuclear context and to environmental cues

Evaluation of turbulent dissipation rate retrievals from Doppler Cloud Radar

Turbulent dissipation rate retrievals from cloud radar Doppler velocity measurements are evaluated using independent, in situ observations in Arctic stratocumulus clouds. In situ validation data sets of dissipation rate are derived using sonic anemometer measurements from a tethered balloon and high frequency pressure variation observations from a research aircraft, both flown in proximity to stationary, ground-based radars. Modest biases are found among the data sets in particularly low- or high-turbulence regimes, but in general the radar-retrieved values correspond well with the in situ measurements. Root mean square differences are typically a factor of 4-6 relative to any given magnitude of dissipation rate. These differences are no larger than those found when comparing dissipation rates computed from tetheredballoon and meteorological tower-mounted sonic anemometer measurements made at spatial distances of a few hundred meters. Temporal lag analyses suggest that approximately half of the observed differences are due to spatial sampling considerations, such that the anticipated radar-based retrieval uncertainty is on the order of a factor of 2-3. Moreover, radar retrievals are clearly able to capture the vertical dissipation rate structure observed by the in situ sensors, while offering substantially more information on the time variability of turbulence profiles. Together these evaluations indicate that radar-based retrievals can, at a minimum, be used to determine the vertical structure of turbulence in Arctic stratocumulus clouds

A compact acoustic calibrator for ultra-high energy neutrino detection

With the aim to optimize and test the method of acoustic detection of ultra-high energy neutrinos in underwater telescopes a compact acoustic transmitter array has been developed. The acoustic parametric effect is used to reproduce the acoustic signature of an ultra-high-energy neutrino interaction. Different R&D studies are presented in order to show the viability of the parametric sources technique to deal with the difficulties of the acoustic signal generation: a very directive transient bipolar signal with 'pancake' directivity. The design, construction and characterization of the prototype are described, including simulation of the propagation of an experimental signal, measured in a pool, over a distance of 1 km. Following these studies, next steps will be testing the device in situ, in underwater neutrino telescope, or from a vessel in a sea campaign. (c) 2012 Elsevier B.V. All rights reserved.This work has been supported by the Ministerio de Ciencia e Innovacion (Spanish Government), project references FPA2009-13983-C02-02, ACI2009-1067, Consolider-Ingenio Multidark (CSD2009-00064). It has also been funded by Generalitat Valenciana, Prometeo/2009/26.Adrián Martínez, S.; Ardid Ramírez, M.; Bou Cabo, M.; Larosa, G.; Llorens Alvarez, CD.; Martínez Mora, JA. (2013). A compact acoustic calibrator for ultra-high energy neutrino detection. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 725:219-222. https://doi.org/10.1016/j.nima.2012.11.142S21922272