32 research outputs found
Safety of switching from intravenous to subcutaneous rituximab during first-line treatment of patients with non-Hodgkin lymphoma: the Spanish population of the MabRella study
- Author
- Publication venue
- 'Royal College of Obstetricians & Gynaecologists (RCOG)'
- Publication date
- 01/01/2020
- Field of study
Rituximab is a standard treatment for non-Hodgkin diffuse large B-cell
(DLBCL) and follicular (FL) lymphomas. A subcutaneous formulation was
developed to improve the resource use of intravenous rituximab, with comparable efficacy and safety profiles except for increased administration-related reactions (ARRs). MabRella was a phase IIIb trial to assess the safety
of switching from intravenous to subcutaneous administration of rituximab
during first-line induction/maintenance for DLBCL or FL, focusing on
ARRs. Efficacy, satisfaction and quality of life were also assessed. Patients
received subcutaneous rituximab plus standard induction chemotherapy for
DLBCL or FL for 4–7 cycles, and/or every 2 months maintenance
monotherapy for FL for 6–12 cycles. The study included 140 patients:
DLBCL, n = 29; FL, n = 111. Ninety-five percent of patients experienced
adverse events, reaching grade ≥3 in 38 6% and were serious in 30 0%.
AARs occurred in 48 6%, mostly (84 9%) at the injection site, with only
2 1% of patients reaching grade 3. The end-of-induction complete/unconfirmed complete response rate was 69 6%. After a median follow-up of
33 5 months, median disease-/event-/progression-free and overall survivals
were not attained. The Rituximab Administration Satisfaction Questionnaire showed improvements in overall satisfaction and the EuroQoL-5D a
good quality-of-life perception at induction/maintenance end. Therefore,
switching to subcutaneous rituximab showed no new safety issues and
maintained efficacy with improved satisfaction and quality of life
Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry
- Author
- Abdelsayed A.A. (Abeer Abeer)
- Acosta A. (Adriana)
- Adams H. (Heath)
- Agostinho J. (João)
- Agostoni P. (Piergiuseppe)
- Airò E. (Edoardo)
- Al Dalaan A. (Abdullah)
- Alexandre M. (Myriam)
- Alexeeva D.E. (Dalyana Eduardovna)
- Alfetlawi M. (Monthir)
- Almagro R.M. (Raúl Menor)
- Alonso L.P. (Lecue Pilar)
- Altraja A. (Alan)
- Andreassen A.K. (Arne K.)
- Anton L. (Ly)
- Argiento P. (Paola)
- Arjona J.J. (Josefa Jiménez)
- Asencio I. (Isabel)
- Atas H. (Halil)
- Avdeev S.N. (Sergey Nikolaevich)
- Avilés F.F. (Francisco Fernandez)
- Badagliacca R. (Roberto)
- Baptista R. (Rui)
- Barberá J.A. (Joan A.)
- Barry L. (Lisa)
- Bartfay S.-E. (Sven-Erik)
- Batalina M.V. (Marina Vadimovna)
- Bauleo C. (Carolina)
- Blanco I. (Isabel)
- Bohacekova M. (Marcela)
- Boogaard H. (H.)
- Boomars K.A.T. (Karin)
- Boonstra A. (Anco)
- Bosio M. (Martin)
- Bruno N. (Noemi)
- Bukatova I.F. (Irina Fedorovna)
- Camacho R.C. (Rafael Conde)
- Campo F. (Felipe)
- Caneva J. (Jorge)
- Capinha M. (Marta)
- Cardoso T. (Tania)
- Castro G. (Graça)
- Cheng C.-C. (Chin-Chang)
- Chu C.Y. (Chun Yuan)
- Church C. (Colin)
- Cifrián Martínez J.M. (José Manuel)
- Conte L. (Luca)
- Correra A. (Anna)
- Corris P. (Paul)
- Costa S. (Serena)
- Cottin V. (Vincent)
- Coutinho D. (Daniel)
- Cresci C. (Chiara)
- Cuesta V.M. (Victor Mora)
- Cárdenas S.L. (Salvador López)
- D'Alto M. (Michele)
- D'Armini A.M. (Andrea Maria)
- De La Pava S. (Sebastian)
- De Luca A. (Anna)
- De Pauw M. (Michel)
- Delcroix M. (Marion)
- Deleo S. (Sabino)
- Di Marco G.M. (Giovanni Maria)
- Diez M. (Mirta)
- Dwyer N. (Nathan)
- Egenlauf B. (Benjamin)
- Elias T. (Teresa)
- Escribano Subías P. (Pilar)
- Espinha M. (Mafalda)
- Evrard P. (Patrick)
- Ewert R. (Ralf)
- Fanaridis M. (Michail)
- Farina S. (Stefania)
- Farkasova I. (Iveta)
- Farruggio S. (Silvia)
- Feenstra J. (John)
- Feistmantl L.-T. (Lisa-Theresa)
- Fernandez D.I. (David Iturbe)
- Filippov E.V. (Evgeny Vladimirovich)
- Fong M.-C. (Man-Cai)
- Gaine S. (Sean)
- Galgano G. (Giuseppe)
- Gall H. (Henning)
- Galyavich A.S. (Albert Sarvatovich)
- Garcea A. (Alessio)
- Garcia A. (Alberto)
- Garcia P. (Paula)
- García S.A. (Salvador Alcaraz)
- Gasche-Soccal P. (Paola)
- Georgopoulos D. (Dimitrios)
- Gerhardt F. (Felix)
- Ghofrani H.A.
- Giannakoulas G. (George)
- Gomez Sanchez M.-A. (Miguel-Angel)
- Gomez J.E. (Juan Esteban)
- Grazioli V. (Valentina)
- Grimminger J. (Jan)
- Gruenberger M. (Margarethe)
- Grünig E. (Ekkehard)
- Guiot J. (Julien)
- Halank M. (Michael)
- Hanta I. (Ismail)
- Harbaum L. (Lars)
- Hegya D.V. (Daria Viktorovna)
- Helmersen D.S. (Douglas S.)
- Ho W.-J. (Wan-Jing)
- Hoeper M.M. (Marius M.)
- Hsu C.-H. (Chih-Hsin)
- Hsu P.-C. (Po-Chao)
- Hsu T.-S. (Tsu-Shiu)
- Huang C.-L. (Chien-Lung)
- Huang W.-C. (Wei-Chun)
- Huang W.-P. (Wen-Pin)
- Huber C. (Charlotte)
- Humbert M.
- Hung C.-S. (Chi-Sheng)
- Ivanov K.I. (Kyundyul Ivanovich)
- Jansa P. (Pavel)
- Jara L. (Luis)
- Karvounis H.I.
- Keogh A. (Anne)
- Klose H. (Hans)
- Klotsche J. (Jens)
- Knoop-Busch S. (Susanne)
- Kolomeytseva T.M. (Tatyana Mikhaylovna)
- Konstantinides S. (Stavros)
- Kotlyar E. (Eugene)
- Kotsia A. (Anna)
- Kramer T. (Tilmann)
- Kulka C. (Christine)
- Kuo P.-H. (Ping-Hung)
- Kuo S.-H. (Shu-Hung)
- Lador F. (Frédéric)
- Lai W.-T. (Wen-Ter)
- Lang I. (Irene)
- Lange T.J. (Tobias J.)
- Langleben D. (David)
- Lavender M. (Melanie)
- Lema C. (Camila)
- Lin J.-L. (Jiunn-Lee)
- Lin T.-H. (Tsung-Hsien)
- Lin Y.-H. (Yen-Hung)
- Lombardi F. (Francesco)
- Londoño A. (Alejandro)
- Lopez M. (Manuel)
- Lopez R. (Raquel)
- Louis R. (Renaud)
- Loureiro M.J. (Maria José)
- Lunardi C. (Claudio)
- Löffler-Ragg J. (Judith)
- Mackenzie M. (Michele)
- Mager J. (J.)
- Maldonado L. (Lorena)
- Manzi G. (Giovanna)
- Marinho A. (António)
- Marrero F.L. (Fernando León)
- Martinez W. (William)
- Martinez-Meñaca A. (Amaya)
- Martins Jesus S.M. (Susana Maria)
- Martynyuk T.V. (Tamila Vitalievna)
- Massola G. (Giulia)
- Mehta S. (Sanjay)
- Meier C. (Christian)
- Melatini L. (Luciano)
- Mellemkjaer S. (Soren)
- Michalis L.K. (Lampros)
- Mielniczuk L.M. (Lisa M.)
- Minson R. (Robert)
- Mitrouska I. (Ioanna)
- Mouratoglou S. (Sofia)
- Mulè M. (Massimiliano)
- Mutlu B. (Bülent)
- Naldi M. (Marco)
- Ndreu R. (Rudina)
- Newnham M. (Michael)
- Ng B. (Benjamin)
- Nielsen-Kudsk J.E. (Jens Erik)
- Nikolaevich B.A. (Bykov Aleksander)
- Nolde A. (Anna)
- Noël-Savina E. (Elise)
- Okumus G. (Gulfer)
- Oliveira A. (Ana)
- Olzik I. (Ilona)
- Ongen G. (Gul)
- Oqueka T. (Tim)
- Orozco-Levi M. (Mauricio)
- Otero R. (Remedios)
- Paciocco G. (Giuseppe)
- Pane F. (Federico)
- Pappas A. (Athanasios)
- Pappas K. (Konstantinos)
- Pavlickova I. (Ivana)
- Pavlova O.B. (Olga Borisovna)
- Peacock A. (Andrew)
- Pepke-Zaba J. (Joanna)
- Pesci A. (Alberto)
- Petruzzi M. (Mario)
- Peñate G.P. (Gregorio Pérez)
- Picariello C. (Claudio)
- Piccari L. (Lucilla)
- Pin M. (Maurizio)
- Pitsiou G. (Georgia)
- Pittrow D. (David)
- Platonov D.Y. (Dmitry Yurievich)
- Poscia R. (Roberto)
- Prediletto R. (Renato)
- Proudman S. (Susanna)
- Quezada C.A. (Carlos Andres)
- Reesink H.J. (Herre)
- Reeves G. (Glenn)
- Regotta S. (Sabine)
- Repolho D. (Débora)
- Rocha A. (Andreia)
- Rochat T. (Thierry)
- Rodríguez P.V. (Patricia Villanueva)
- Roman A. (Antonio)
- Roncon L. (Loris)
- Rosenkranz S. (Stephan)
- Rozas S.F. (Sonia Fernandez)
- Rundqvist B. (Bengt)
- Sadushi-Kolici R. (Roela)
- Sakkijha H. (Hussam)
- Saleemi S. (Sarferaz)
- Sardella L. (Luca)
- Schulz C. (Christian)
- Schwarz E.I. (Esther Irene)
- Sciortino A. (Antonio)
- Sebastian L. (Laura)
- Shearman N. (Nicole)
- Shiang T. (Teresa)
- Simon M. (Marcel)
- Simonneau G. (Gérald)
- Sitbon O. (Olivier)
- Skripkina E.S. (Elena Sergeevna)
- Snijder R.
- Sourla E. (Evdokia)
- Sousa J. (Joana)
- Speich R. (Rudolf)
- Stanopoulos I. (Ioannis)
- Steele P. (Peter)
- Steringer-Mascherbauer R. (Regina)
- Stevens W. (Wendy)
- Su H.-M. (Ho-Ming)
- Sung S.-H. (Shih-Hsien)
- Söderberg S. (Stefan)
- Talavera M.L. (Maria Lujan)
- Tania G. (Gonçalves)
- Tayler S. (Susanne)
- Tilea I. (Ioana)
- Toorn L.M. (Leon) van den
- Torricelli E. (Elena)
- Toshner M. (Mark)
- Tovar P.P. (Patricia Parada)
- Tregubova A.V. (Anna Viktorovna)
- Tsangaris I. (Iraklis)
- Tsareva N.A. (Natalia Anatolievna)
- Tuhay G. (Graciela)
- Têtu L. (Laurent)
- Ulrich S. (Silvia)
- Un Z. (Zeynep)
- Vachiéry J.-L. (Jean-Luc)
- Valkovicova T. (Tatiana)
- Vannucchi V. (Vieri)
- Vasankari T. (Tuija)
- Vihinen T. (Tapani)
- Vizza C.D. (Carmine Dario)
- Vonk Noordegraaf A. (Anton)
- Voon W.-C. (Wen-Chol)
- Vulcano N. (Norberto)
- Wang W.-H. (Wen-Hwa)
- Weheba I. (Ihab)
- Williams E. (Evgenia)
- Wirtz G. (Gil)
- Wirtz H. (Hubert)
- Wodlin P. (Peter)
- Wu C.-K. (Cho-Kai)
- Wu S.-H. (Shu-Hao)
- Yakovleva O.E. (Olga Eduardovna)
- Yen H.-W. (Hsueh-Wei)
- Yih-Jer Wu J. (Jacob)
- Yotti R. (Raquel)
- Zvereva T.N. (Tatyana Nikolaevna)
- Šimková I. (Iveta)
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/03/2021
- Field of study
Objective: The soluble guanylate cyclase stimulator riociguat is approved for the treatment of adult patients with pulmonary arterial hypertension (PAH) and inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH) following Phase
Safety of switching from intravenous to subcutaneous rituximab during first-line treatment of patients with non-Hodgkin lymphoma: the Spanish population of the MabRella study
- Author
- Publication venue
- 'Royal College of Obstetricians & Gynaecologists (RCOG)'
- Publication date
- 01/01/2020
- Field of study
Rituximab is a standard treatment for non-Hodgkin diffuse large B-cell
(DLBCL) and follicular (FL) lymphomas. A subcutaneous formulation was
developed to improve the resource use of intravenous rituximab, with comparable efficacy and safety profiles except for increased administration-related reactions (ARRs). MabRella was a phase IIIb trial to assess the safety
of switching from intravenous to subcutaneous administration of rituximab
during first-line induction/maintenance for DLBCL or FL, focusing on
ARRs. Efficacy, satisfaction and quality of life were also assessed. Patients
received subcutaneous rituximab plus standard induction chemotherapy for
DLBCL or FL for 4–7 cycles, and/or every 2 months maintenance
monotherapy for FL for 6–12 cycles. The study included 140 patients:
DLBCL, n = 29; FL, n = 111. Ninety-five percent of patients experienced
adverse events, reaching grade ≥3 in 38 6% and were serious in 30 0%.
AARs occurred in 48 6%, mostly (84 9%) at the injection site, with only
2 1% of patients reaching grade 3. The end-of-induction complete/unconfirmed complete response rate was 69 6%. After a median follow-up of
33 5 months, median disease-/event-/progression-free and overall survivals
were not attained. The Rituximab Administration Satisfaction Questionnaire showed improvements in overall satisfaction and the EuroQoL-5D a
good quality-of-life perception at induction/maintenance end. Therefore,
switching to subcutaneous rituximab showed no new safety issues and
maintained efficacy with improved satisfaction and quality of life
Effectiveness of the combination elvitegravir/cobicistat/tenofovir/emtricitabine (EVG/COB/TFV/FTC) plus darunavir among treatment-experienced patients in clinical practice : A multicentre cohort study
- Author
- Adsuar A.
- Agea I.
- Alba V.
- Albendin H.
- Alcaraz B.
- Alcaraz M.J.
- Alcáriz N.S.
- Aldamiz-Echevarría T.
- Aldeguer J.L.
- Alejos B.
- Alemán M.R.
- Alonso M.M.
- Alonso N.
- Amador C.
- Amador C.
- Amengual Guedan Maria Jose
- Anguita C.G.
- Antela A.
- Aparicio A.S.
- Aramburu M.J.
- Arazo P.
- Arnalich F.
- Arribas J. R.
- Arrizabalaga J.
- Asensi V.
- Ayerbe C.G.
- Ayerdi O.
- Azkarreta I.L.
- Azkune H.
- Ballesteros J.
- Balsalobre P.
- Baraia-Etxaburu J.M.
- Barber X.
- Beltran C.G.
- Beneitez O.L.F.
- Benito C.
- Berenguer Juan
- Bermejo L.
- Bernal E.
- Bisbal O.
- Blanco J.R.
- Boix V.
- Bustinduy M.J.
- Cabello A.
- Cairó M.
- Calzado Isbert Sonia
- Camino X.
- Campins A.A.
- Carmenado M.E.R.
- Carreres M.
- Carrió J.C.
- Casas M.F.
- Caso A.A.
- Castellanos A.J.
- Castro J.M.
- Cepeda C.S.
- Cervantes Garcia Manel
- Chueca N.
- Colomé J.G.
- Crespo M.
- Crestelo D.R.
- Curran Fábregas Adria
- Dalmau D.
- Dalmau D.
- De Alda M.G.R.
- De Cea A.M.
- De Galarreta B.P.R.
- De La Peña M.
- De La Serna J.I.B.
- De La Torre J.
- De León Cano M.T.
- De Lomas Guerrero J.M.G.
- De Los Santos I.
- De Munain J.L.
- De Quirós J.C.L.B.
- De Salazar Gonzalerz A.
- De Zarraga M.A.
- De Zarraga M.A.
- Del Arco A.
- Del Campo Terrón S.
- Del Carmen Villalba M.
- Del Mar Alonso M.
- Del Romero J.
- Diez C.
- Domínguez L.
- Díaz-Flores F.
- Díez Martínez M.
- Díez M.
- Elías M.J.P.
- Ena J.
- Escosa L.
- Espejo A.C.
- Espinosa N.
- Fanciulli C.
- Fanjul F.
- Fenoll V.
- Fernández I.C.
- Fernández M.
- Font R.
- Fraile L.G.F.
- Fuertes M.F.
- Fuster Daniel
- Galera C.
- Gallego M.J.V.
- García A.A.
- García D.
- García D.V.
- García E.
- García F.
- García F.
- García G.
- García J.
- García J. A.
- García J.V.
- García-Bujalance S.
- Gayo E.M.
- Gijón P.
- Gimeno L.
- Giner L.
- Goenaga M.Á.
- Gomez A.C.
- Gonzalez-Domenec C.M.
- Gonzalez-Serna A.
- González J.
- González M.I.
- González-Baeza A.
- González-Garcia J.
- González-Ruano P.
- Gutierrez N.M.
- Gutiérrez C.
- Gutiérrez C.H.
- Gutiérrez F.
- Gutiérrez F.
- Gutiérrez I.
- Gómez J.L.
- Górgolas M.
- Górgolas M.
- Hernando A.
- Hernández I.C.
- Hernández J.
- Hernández M.I.
- Herranz P.
- Homar F.
- Hontañón V.
- Ibarguren M.
- Ibarra V.
- Iborra A.
- Igartua M.U.
- Iglesias A.C.
- Imaz Arkaitz
- Iniesta C.
- Iribarren J.A.
- Iribarren J.A.
- Is L.P.
- Jarrin I.
- Jarrin I.
- Jarrin I.
- Jaén A.
- Jimeno A.
- Jiménez M.C.
- Juliá M.B.
- Juárez A.R.
- Kortajarena X.
- Latorre L.P.
- Leyes M.
- Lirola A.L.
- Lizardi A.
- Lletí M.S.
- Lopez A.F.
- Lopez M.
- Losada E.
- López C.P.
- López M.M.C.
- López P.L.
- López-Cortés L.F.
- López-Dupla M.
- López-Hortelano M.G.
- Madrid N.
- Malmierca E.
- Marcotegui M.R.
- Martinez-Lacasa J.
- Martinez-Montes C.
- Martín-Carbonero M.L.
- Martínez L.
- Martínez O.J.
- Masiá M.
- Mayo P.R.
- Mayoral M.
- Meca M.
- Medina L.M.
- Mellado M.J.
- Mena M.N.
- Merino E.
- Merlos M.A.
- Metola L.
- Micán R.E.
- Miralles C.
- Mohamed-Balghata M.O.
- Molina M.J.T.
- Montejano R.
- Montes M.L.
- Montolio F.
- Morano L.
- Moreno A.
- Moreno C.
- Moreno Cristina
- Moreno J.P.S.
- Moreno J.S.
- Moreno S.
- Moreno S.
- Moreno V.
- Muga Roberto
- Murillas J.
- Muñoz E.C.
- Muñoz J.
- Muñoz-Fernández M.Á.
- Muñoz-Fernández M.Á.
- Navarro Rubio Gemma
- Navarro A.
- Navarro J.F.
- Navarro M. L.
- Navarro Marta
- Nuñez F.D.
- Ocampo A.
- Olona M.
- Osorio J.L.C.
- Oteo J.A.
- Oyaga M.P.C.
- Padilla B.
- Padilla S.
- Palacios R.
- Parras F.J.
- Pascual R.
- Pasquau F.
- Pelazas R.
- Peraire J.
- Perea R.T.
- Perez A.M.
- Perez N.S.
- Peñaranda M.
- Pineda J.A.
- Pitarch M.T.
- Podzamczer Daniel
- Portilla I.
- Portilla J.
- Pousada G.
- Poveda E.
- Poveda E.
- Prada J.L.
- Prieto L.
- Prieto Paula
- Puerta T.
- Puerto M.J.G.
- Pulido F.
- Pérez A.
- Pérez A.
- Pérez V.E.
- Pérez-Elías M.J.
- Pérez-Martínez L.
- Pérez-Martínez L.
- Pérez-Valero I.
- Quero J.H.
- Rabasa J.T.A.
- Ramírez M.
- Rava M.
- Real L.M.
- Repáraz J.
- Reus S.
- Ribas M.A.
- Ribera A.F.
- Ribera Esteban
- Riera M.
- Robledano C.
- Rodrigo D.M.
- Rodríguez C.
- Rodríguez J.C.
- Rodríguez-Arrondo F.
- Rodríguez-Gallego E.
- Rodés B.
- Román A.R.
- Rubio R.
- Rubio R.
- Ruiz-Algueró M.
- Rull A.
- Sainz T.
- Sampériz G.
- Sanchez A.C.
- Sanchez J.M.
- Sanmartí M.
- Santacreu M.
- Santos J.
- Sanvisens Arantza
- Sanz J.M.
- Sanz J.S.
- Sanz M.
- Saumoy María
- Secades T.S.Z.
- Seco M.P.R.
- Sendagorta E.
- Sierra J.O.
- Silva Ana
- Sousa L.M.G.
- Souto B.P.
- Stachowski J.P.
- Suárez-García I.
- Suárez-García Inés
- Sánchez I. M.
- Sánchez-Payá J.
- Tejerina F.
- Tiraboschi Juan
- Tomé L.P.
- Torrús D.
- Tovar S.C.
- Ugarte S.I.
- Urbieta J.B.
- Urroz U.A.
- Utrilla M.R.
- Valencia E.
- Valle E.
- Vargas M.
- Velasco T.
- Velli P.
- Veloso S.
- Vera F.J.
- Vera M.
- Viciana I.
- Viciana P.
- Viciana P.
- Vidal A.
- Vidal C.
- Vidal F.
- Vidal F.
- Vidal M.A.G.
- Viladés C.
- Vilalta R.F.
- Villar S.S.
- Von Wichmann M.Á.
- Xercavins M.
- Zamora A.M.
- Zubero M.Z.
- Álvarez B.
- Álvarez Mar
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Background: The aim of this study was to investigate the effectiveness and tolerability of the combination elvitegravir/cobicistat/tenofovir/emtricitabine plus darunavir (EVG/COB/TFV/FTC + DRV) in treatment-experienced patients from the cohort of the Spanish HIV/AIDS Research Network (CoRIS). Methods: Treatment-experienced patients starting treatment with EVG/COB/TFV/FTC + DRV during the years 2014-2018 and with more than 24 weeks of follow-up were included. TFV could be administered either as tenofovir disoproxil fumarate or tenofovir alafenamide. We evaluated virological response, defined as viral load (VL) < 50 copies/ml and < 200 copies/ml at 24 and 48 weeks after starting this regimen, stratified by baseline VL (< 50 or ≥ 50 copies/ml at the start of the regimen). Results: We included 39 patients (12.8% women). At baseline, 10 (25.6%) patients had VL < 50 copies/ml and 29 (74.4%) had ≥ 50 copies/ml. Among patients with baseline VL < 50 copies/ml, 85.7% and 80.0% had VL < 50 copies/ml at 24 and 48 weeks, respectively, and 100% had VL < 200 copies/ml at 24 and 48 weeks. Among patients with baseline VL ≥ 50 copies/ml, 42.3% and 40.9% had VL < 50 copies/ml and 69.2% and 68.2% had VL < 200 copies/ml at 24 and 48 weeks. During the first 48 weeks, no patients changed their treatment due to toxicity, and 4 patients (all with baseline VL ≥ 50 copies/ml) changed due to virological failure. Conclusions: EVG/COB/TFV/FTC + DRV was well tolerated and effective in treatment-experienced patients with undetectable viral load as a simplification strategy, allowing once-daily, two-pill regimen with three antiretroviral drug classes. Effectiveness was low in patients with detectable viral loads
EpidemIBD: rationale and design of a large-scale epidemiological study of inflammatory bowel disease in Spain
- Author
- A Bouhmidi
- A. Abraldes
- A. Algaba
- A. Carmona
- A. Castiella
- A. Durán
- A. Echarri
- A. García
- A. Garre
- A. Gutiérrez
- A. Hernández Camba
- A. Hernández-Martínez
- A. López
- A. López-Sanromán
- A. Mancebo
- A. Maíz
- A. Mir
- A. Monrobel
- A. Montserrat
- A. Núñez
- A. Ponferrada
- A. Sapiña
- A. Silva
- A.G. McNicholl
- A.I. Muñagorri Santos
- A.J. Lucendo
- A.M. Fuentes
- Alonso P
- Ana Garre
- Anton Martinez J
- Arin Letamendia A
- B. Botella
- B. Crespo
- B. Herreros
- B. Lapeña
- B. López-Cauce
- B. Sicilia
- Beatriz Sicilia
- Brullet E
- Brullet E
- C. Castaño-Milla
- C. Ledezma
- C. López
- C. Martínez Pascual
- C. Piñero
- C. Rodríguez
- C. Rodríguez
- C. Verdejo
- C. Vila
- Cella Lanau J
- Chaaro Benallal D
- Cristina Rodríguez
- D. Carpio
- D. Ceballos
- D. Ginard
- D. Hervías
- Daniel Ceballos
- Daniel Ginard
- E. Alfambra
- E. Castro
- E. Fernández
- E. Guerra
- E. Iglesias
- E. Iyo
- E. Leo
- E. Peña
- E. Sainz
- E. San Miguel
- E. Sesé
- E. Sánchez
- E. Torrella
- E.M. Zapata
- Emilio Torrella
- Esther García-Esquinas
- F. Bermejo
- F. Gomollón
- F.J. Martínez-Cerezo
- Fernando Gomollón
- Fernando Rodríguez-Artalejo
- García-Cano Lizccano J
- H. Alonso
- H. Fernández
- Hinojosa J
- Hipólito Fernández
- I. Alonso- Abreu
- I. Bastón-Rey
- I. Blázquez
- I. Galdona
- I. Guerra
- I. Marín-Jiménez
- I. Nicolás
- I. Pérez-Martínez
- I. Rodríguez-Lago
- I. Vera-Mendoza
- J. Barrio
- J. Gordillo
- J. Ortiz
- J. Reyes
- J.A. Gómez- Valero
- J.A. Olmos
- J.D. Fernández-de Castro
- J.J. Ramírez
- J.L. Cabriada
- J.L. Pérez-Calle
- J.L.F. Forcelledo
- J.M. Benítez
- J.M. Castillo-Espinosa
- J.M. Duque
- J.M. Huguet
- J.M. Marrero
- J.M. Nerín
- J.P. Gisbert
- Javier P. Gisbert
- José Luis Cabriada
- José Manuel Benítez
- K. Spicakova
- L. Arias
- L. Fernández-Salazar
- L. García
- L. Hernández
- L. Kolle
- L. Lluis
- L. Martí
- L. Mata
- L. Pozzati
- L. Torrealba
- L. Zubiaurre
- Lopez Miguel C
- Lucendo AJ
- M. Aceituno
- M. Aguas
- M. Barreiro-de Acosta
- M. Bautista
- M. Calafat
- M. Chaparro
- M. Domínguez-Antonaya
- M. Esteve
- M. Fraile
- M. García-Sepulcre
- M. Kutz
- M. Menacho
- M. Montealegre
- M. Montoro
- M. Muñoz
- M. Mínguez
- M. Navarro- Llavat
- M. Rivero
- M. Roldán
- M. Sabat
- M. Sierra
- M. Soler
- M. Tejada
- M. Vela
- M. Vicuña
- M. Vásquez
- M. Ágreda Chinea
- M.C. Martínez Bonil
- M.D. Martín-Arranz
- M.G. Donday
- M.J. Alcalá
- M.J. Casanova
- M.J. Ruiz
- M.J. Sampedro
- M.L. Galve
- M.R. Calderón
- M.T. Diz-Lois
- M.T. Novella
- Manuel Barreiro-de Acosta
- Martinez G
- Martínez Sabater A
- María Chaparro
- María Esteve
- María José Casanova
- Monferrer Guardiola R
- Montserrat Rivero
- N. Cruz
- N. Jiménez
- N. Maroto
- N. Muro
- N. Otegui
- N. Pérez
- N. Ruiz
- O. Bosch
- O. Roncero
- P. Fradejas
- P. Jiménez
- P. López
- P. Navarro
- P. Nos
- P. Pérez
- P. Robledo
- P. Varela
- P. Vega
- Pajares Garcia JM
- Pilar Nos
- Pilar Robledo
- R. Camargo
- R. de Francisco
- R. de Lucas
- R. Ferreiro-Iglesias
- R. Irisarri
- R. Lorente
- R. Plaza
- R. Vicente
- Rufo Lorente
- Ruiz Ochoa V
- S. Martínez-González
- S. Marín
- S. Revuelta
- S. Riestra
- S. Rodríguez
- S. Rubio
- S. Torra
- Sabino Riestra
- Saro Gismera C
- Sebastian Domingo JJ
- Sola Lamoglia R
- Sturm A
- V. Hernández
- V. Opio
- V. Royo
- X. Calvet
- Y. Ber
- Y. Torres
- Ó. Nantes
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Heart Rate and Mortality in Patients With Acute Symptomatic Pulmonary Embolism
- Author
- Accassat S.
- Adarraga M.D.
- Aibar J.
- Aibar M.A.
- Ait Abdallah N.
- Alonso J.
- Amado C.
- Arcelus J.I.
- Asuero A.
- Ay C.
- Azcarate-Agüero P.
- Ballaz A.
- Barba R.
- Barba Raquel
- Barbagelata C.
- Barrón M.
- Barrón-Andrés B.
- Basaglia M.
- Beddar Chaib F.
- Bertoletti L.
- Bertoletti Laurent
- Bikdeli B.
- Bikdeli Behnood
- Bilora F.
- Birzulis J.
- Blanco-Molina A.
- Bortoluzzi C.
- Bosevski M.
- Bosevski Marijan
- Bounameaux H.
- Bounameaux Henri
- Braester A.
- Brandolin B.
- Brenner B.
- Brenner Benjamin
- Bui H.M.
- Bui Hanh My
- Bura-Riviere A.
- Camon A.M.
- Caprini J.A.
- Caprini Joseph
- Castro J.
- Catella J.
- Chasco L.
- Ciammaichella M.
- Couturaud F.
- Criado J.
- Crichi B.
- de Ancos C.
- De Angelis A.
- Debourdeau P.
- del Toro J.
- Demelo-Rodríguez P.
- Di Campli M.V.
- Di Micco P.
- Di Micco Pierpaolo
- Dubois-Silva A.
- Díaz-Brasero A.M.
- Díaz-Pedroche M.C.
- Díaz-Peromingo J.A.
- Escribano J.C.
- Espitia O.
- Espósito F.
- Farfán-Sedano A.I.
- Farge-Bancel D.
- Farge-Bancel Dominique
- Fernández-Capitán C.
- Fernández-Reyes J.L.
- Fidalgo M.A.
- Flores K.
- Fonseca S.
- Font C.
- Font L.
- Francisco I.
- Gabara C.
- Galeano-Valle F.
- García de Herreros M.
- García de la Garza R.
- García M.A.
- García-Bragado F.
- García-Díaz C.
- Gil-Díaz A.
- Giménez-Suau M.
- Grange C.
- Grau E.
- Guirado L.
- Gutiérrez J.
- Gómez-Cuervo C.
- Helfer H.
- Hernández-Blasco L.
- Hirmerova J.
- Imbalzano E.
- Jara-Palomares L.
- Jaras M.J.
- Jaureguízar Ana
- Jiménez D.
- Jiménez David
- Jiménez-Alfaro C.
- Joya M.D.
- Kenet G.
- Kenet Gili
- Krstevski G.
- Lacut K.
- Lainez-Justo S.
- Latorre A.
- Le Mao R.
- Lima J.
- Lobo J.L.
- Lorenzo A.
- López-Jiménez L.
- López-Miguel P.
- López-Núñez J.J.
- López-Reyes R.
- López-Reyes Raquel
- López-Sáez J.B.
- Madridano O.
- Maestre A.
- Mahé I.
- Malý R.
- Malý Radovan
- Marchena P.J.
- Martins F.
- Martín del Pozo M.
- Martín-Martos F.
- Martínez-Urbistondo D.
- Mazzolai L.
- Meireles J.
- Mella C.
- Mercado M.I.
- Merla S.
- Moisés J.
- Monreal M.
- Monreal Manuel
- Monreal Manuel
- Morange P.
- Moustafa F.
- Muriel Alfonso
- Muñoz M.
- Muñoz-Blanco A.
- Nieto J.A.
- Nishimoto Y.
- Nofuentes-Pérez E.
- Nopp S.
- Núñez-Fernández M.J.
- Olid-Velilla M.
- Olivares M.C.
- Osorio J.
- Otalora S.
- Otero R.
- Pabinger I.
- Pedrajas J.M.
- Pellejero G.
- Pesavento R.
- Poenou G.
- Porras J.A.
- Portillo J.
- Prandoni P.
- Prandoni Paolo
- Quere I.
- Reis Abilio
- Rodríguez-Matute C.
- Rosa V.
- Ruiz-Artacho P.
- Ruiz-Artacho Pedro
- Ruiz-Ruiz J.
- Salgueiro G.
- Sancho T.
- Sarlon-Bartoli G.
- Sato Y.
- Schellong S.
- Schellong Sebastian
- Siniscalchi C.
- Skride A.
- Soler S.
- Suchon P.
- Suriñach J.M.
- Suárez-Rodríguez B.
- Sánchez-Martínez R.
- Sánchez-Muñoz-Torrero J.F.
- Tapson Victor
- Tolosa C.
- Torres M.I.
- Trujillo-Santos J.
- Tufano A.
- Tzoran I.
- Tzoran Inna
- Uresandi F.
- Valero B.
- Valero Beatriz
- Valle R.
- Vanassche T.
- Vandenbriele C.
- Varona J.F.
- Vela J.R.
- Vela L.
- Verhamme P.
- Verhamme Peter
- Vidal G.
- Villalobos A.
- Villares P.
- Visonà A.
- Vo Hong N.
- Zaicenko A.
- Zalunardo B.
- Zamora C.
- Publication venue
- American College of Chest Physicians
- Publication date
- 01/02/2022
- Field of study
International audienc
Multi-strange baryon production in pp collisions at (s)^1/2 = 7 TeV with ALICE
- Author
- Abelev B.
- Adam J.
- Adamová D.
- Adare A.M.
- Aggarwal M.M.
- Aglieri Rinella G.
- Agocs A.G.
- Agostinelli A.
- Aguilar Salazar S.
- Ahammed Z.
- Ahmad Masoodi A.
- Ahmad N.
- Ahn S.U.
- Akindinov A.
- Aleksandrov D.
- Alessandro B.
- Alfaro Molina R.
- Alici A.
- Alkin A.
- Almaráz Aviña E.
- Alme J.
- Alt T.
- Altini V.
- Altinpinar S.
- Altsybeev I.
- Andrei C.
- Andronic Anton
- Anguelov V.
- Anielski J.
- Anson C.
- Antinori F.
- Antičić T.
- Antonioli P.
- Aphecetche L.
- Appelshäuser H.
- Arbor N.
- Arcelli S.
- Arend A.
- Armesto N.
- Arnaldi R.
- Aronsson T.
- Arsene Ionut Cristian
- Arslandok M.
- Asryan A.
- Augustinus A.
- Averbeck Ralf
- Awes T.C.
- Azmi M.D.
- Bach M.
- Badalà A.
- Baek Y.W.
- Bailhache R.
- Bala R.
- Baldini Ferroli R.
- Baldisseri A.
- Baldit A.
- Baltasar Dos Santos Pedrosa F.
- Baral R.C.
- Barbera R.
- Barile F.
- Barnaföldi G.G.
- Barnby L.S.
- Barret V.
- Bartke J.
- Basile M.
- Bastid N.
- Basu S.
- Bathen B.
- Batigne G.
- Batyunya B.
- Baumann C.
- Bearden I.G.
- Beck H.
- Belikov I.
- Bellini F.
- Bellwied R.
- Belmont-Moreno E.
- Bencedi G.
- Beole S.
- Berceanu I.
- Bercuci A.
- Berdnikov Y.
- Berenyi D.
- Berzano D.
- Betev L.
- Bhasin A.
- Bhati A.K.
- Bhom J.
- Bianchi L.
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- Bianchin C.
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- Blanco F.
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- Blume C.
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- Bogolyubsky M.
- Boldizsár L.
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- Borissov A.
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- Bossú F.
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- Braidot E.
- Braun-Munzinger Peter
- Bregant M.
- Breitner T.
- Browning T.A.
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- Brun R.
- Bruna E.
- Bruno G.E.
- Budnikov D.
- Buesching H.
- Bufalino S.
- Bugaiev K.
- Busch O.
- Buthelezi Z.
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- Bøggild H.
- Caballero Orduna D.
- Caffarri D.
- Cai X.
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- Canoa Roman V.
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- Carena F.
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- Cruz Alaniz E.
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- Kazantsev A.
- Kebschull U.
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- Khan S.A.
- Khanzadeev A.
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- Kileng B.
- Kim B.
- Kim D.J.
- Kim D.W.
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- Kim J.S.
- Kim M.
- Kim M.
- Kim S.
- Kim S.H.
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- Kisel I.
- Kiselev S.
- Kisiel A.
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- Kliemant M.
- Kluge A.
- Knichel Michael Linus
- Knospe A.G.
- Koch K.
- Kolojvari A.
- Kondratiev V.
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- Korneev A.
- Kour R.
- Kowalski M.
- Kox S.
- Koyithatta Meethaleveedu G.
- Kral J.
- Kramer F.
- Kraus I.
- Krawutschke T.
- Krelina M.
- Kretz M.
- Krivda M.
- Krizek F.
- Krus M.
- Kryshen E.
- Krzewicki Mikolaj
- Králik I.
- Kucheriaev Y.
- Kuhn C.
- Kuijer P.G.
- Kulakov I.
- Kurashvili P.
- Kurepin A.
- Kurepin A.B.
- Kuryakin A.
- Kushpil S.
- Kushpil V.
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- Publication venue
- Elsevier
- Publication date
- 01/01/2012
- Field of study
See paper for full list of authors -A measurement of the multi-strange Xi- and Omega- baryons and their antiparticles by the ALICE experiment at the CERN Large Hadron Collider (LHC) is presented for proton-proton collisions at centre of mass energy of 7 TeV. The transverse momentum (pt) distributions were studied at mid-rapidity (|y| 6.0 GeV/c. We also illustrate the difference between the experimental data and model by comparing the corresponding ratios of (Omega-+Omega+)/(Xi-+Xi+) as a function of transverse mass
Whole-genome sequencing reveals host factors underlying critical COVID-19
- Author
- Abd Elghafar Mohamed S.
- Abdel-Aziz Mahmoud
- Abdelrazik Marwa
- Abdollahi Hamed
- Abdullah T.
- Abecasis Goncalo
- Abedalthagafi M.
- Abel Lynn
- Abernathy C.
- Abraheem Azmeralde
- Abul-Husn Noura S.
- Acquilini D.
- Adams C.
- Adams Emma L.
- Adams K.
- Adamsara Alireza
- Adanini Olurenke
- Adeleye O.
- Adra D.
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- Afolabi D.
- Afrasiabi Z.
- Agasou A.
- Agrawal Shruti
- Agüero D.
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- Ahmadi Saeideh
- Ahmed A.
- Ahmed Cecilia
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- Akhtar M.N.
- Akinkugbe O.
- Aksentijevich Alexandra
- Al-Afghani H.
- Al-Awdah L.
- Alaamery M.
- Alahmadey Z.Z.
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- Åsvold Bjørn Olav
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Altres ajuts: Department of Health and Social Care (DHSC); Illumina; LifeArc; Medical Research Council (MRC); UKRI; Sepsis Research (the Fiona Elizabeth Agnew Trust); the Intensive Care Society, Wellcome Trust Senior Research Fellowship (223164/Z/21/Z); BBSRC Institute Program Support Grant to the Roslin Institute (BBS/E/D/20002172, BBS/E/D/10002070, BBS/E/D/30002275); UKRI grants (MC_PC_20004, MC_PC_19025, MC_PC_1905, MRNO2995X/1); UK Research and Innovation (MC_PC_20029); the Wellcome PhD training fellowship for clinicians (204979/Z/16/Z); the Edinburgh Clinical Academic Track (ECAT) programme; the National Institute for Health Research, the Wellcome Trust; the MRC; Cancer Research UK; the DHSC; NHS England; the Smilow family; the National Center for Advancing Translational Sciences of the National Institutes of Health (CTSA award number UL1TR001878); the Perelman School of Medicine at the University of Pennsylvania; National Institute on Aging (NIA U01AG009740); the National Institute on Aging (RC2 AG036495, RC4 AG039029); the Common Fund of the Office of the Director of the National Institutes of Health; NCI; NHGRI; NHLBI; NIDA; NIMH; NINDS.Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care or hospitalization after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes-including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)-in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease
Freeze-out radii extracted from three-pion cumulants in pp, p–Pb and Pb–Pb collisions at the LHC
- Author
- Abelev Betty
- Adam Jaroslav
- Adamová Dagmar
- Aggarwal Madan Mohan
- Agnello Michelangelo
- Agostinelli A.
- Agrawal Neelima
- Ahammed Zubayer
- Ahmad N.
- Ahmed I.
- Ahn S.A.
- Ahn Sang Un
- Aimo I.
- Aiola Salvatore
- Ajaz M.
- Akindinov Alexander
- Alam Sk Noor
- Aleksandrov Dmitry
- Alessandro Bruno
- Alexandre Didier
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altinpinar Sedat
- Altsybeev Igor
- Andrei Cristian
- Andronic Anton
- Anguelov Venelin
- Anielski J.
- Antinori Federico
- Antičić Tome
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshäuser Harald
- Arbor N.
- Arcelli Silvia
- Armesto N.
- Arnaldi Roberta
- Aronsson T.
- Arsene Ionut Cristian
- Arslandok Mesut
- Augustinus Andre
- Averbeck Ralf Peter
- Awes T.C.
- Azmi Mohd Danish
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- Vercellin Ermanno
- Vergara Limón Sergio
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- Verweij M.
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- Viesti G.
- Viinikainen Jussi Samuli
- Vilakazi Zabulon
- Villalobos Baillie Orlando
- Vinogradov Alexander A.
- Vinogradov Leonid
- Vinogradov Y.
- Virgili Tiziano
- Viyogi Y.P.
- Vodopyanov Alexander
- Voloshin Kirill
- Voloshin Sergei
- Volpe Giacomo
- Vorobyev Ivan
- Vranić Danilo
- Vrláková Janka
- Vulpescu B.
- Vyushin A.
- Vyvre Pierre vande
- Völkl Martin Andreas
- Wagner Boris
- Wagner J.
- Wagner V.
- Wang M.
- Wang Y.
- Watanabe Daisuke
- Weber Michael
- Wessels Johannes P.
- Westerhoff Uwe
- Wiechula Jens
- Wikne Jon
- Wilde M.
- Wilk Grzegorz Andrzej
- Wilkinson Jeremy
- Williams M.C.S.
- Windelband Bernd
- Winn M.
- Xiang C.
- Yaldo C.G.
- Yamaguchi Y.
- Yang H.
- Yang Ping
- Yang S.
- Yano Satoshi
- Yasnopolskiy S.
- Yi J.
- Yin Zhongbao
- Yoo In-Kwon
- Yushmanov I.
- Zaccolo Valentina
- Zach C.
- Zaman Ali
- Zampolli Chiara
- Zaporozhets S.
- Zarochentsev Andrey
- Zaviyalov Nikolaj
- Zbroszczyk Hanna Paulina
- Zgura I.S.
- Zhalov Mikhail
- Zhang Haitao
- Zhang Xiaoming
- Zhang Y.
- Zhao C.
- Zhigareva Natalia
- Zhou Daicui
- Zhou F.
- Zhou You
- Zhou Zhuo
- Zhu Hongsheng
- Zhu Jianhui
- Zhu X.
- Zichichi Antonino
- Zimmermann A.
- Zimmermann Markus Bernhard
- Zinovjev Gennady M.
- Zoccarato Y.
- Zyzak Maksym
- Závada Petr
- Šafařík Karel
- Šumbera Michal
- Šuša Tatjana
- Šándor L.
- Publication venue
- 'Elsevier BV'
- Publication date
- 18/10/2014
- Field of study
In high-energy collisions, the spatio-temporal size of the particle production region can be measured using the Bose–Einstein correlations of identical bosons at low relative momentum. The source radii are typically extracted using two-pion correlations, and characterize the system at the last stage of interaction, called kinetic freeze-out. In low-multiplicity collisions, unlike in high-multiplicity collisions, two-pion correlations are substantially altered by background correlations, e.g. mini-jets. Such correlations can be suppressed using three-pion cumulant correlations. We present the first measurements of the size of the system at freeze-out extracted from three-pion cumulant correlations in pp, p–Pb and Pb–Pb collisions at the LHC with ALICE. At similar multiplicity, the invariant radii extracted in p–Pb collisions are found to be 5–15% larger than those in pp, while those in Pb–Pb are 35–55% larger than those in p–Pb. Our measurements disfavor models which incorporate substantially stronger collective expansion in p–Pb as compared to pp collisions at similar multiplicity
Beauty production in pp collisions at √s=2.76 TeV measured via semi-electronic decays
- Author
- Abelev Betty
- Adam Jaroslav
- Adamová Dagmar
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agostinelli A.
- Agrawal Neelima
- Ahammed Zubayer
- Ahmad N.
- Ahmed I.
- Ahn S.A.
- Ahn Sang Un
- Aimo I.
- Aiola Salvatore
- Ajaz M.
- Akindinov Alexander
- Alam Sk Noor
- Aleksandrov Dmitry
- Alessandro Bruno
- Alexandre Didier
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altinpinar Sedat
- Altsybeev Igor
- Andrei Cristian
- Andronic Anton
- Anguelov Venelin
- Anielski J.
- Antinori Federico
- Antičić Tome
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshäuser Harald
- Arcelli Silvia
- Armesto N.
- Arnaldi Roberta
- Aronsson T.
- Arsene Ionut Cristian
- Arslandok Mesut
- Augustinus Andre
- Averbeck Ralf Peter
- Awes T.C.
- Azmi Mohd Danish
- Bach M.
- Badalà Angela
- Baek Yong Wook
- Bagnasco Stefano
- Bailhache Raphae͏̈lle
- Bala Renu
- Baldisseri Alberto
- Baltasar Dos Santos Pedrosa F.
- Baral Rama Chandra
- Barbera Roberto
- Barile Francesco
- Barnaföldi Gergely Gábor
- Barnby Lee Stuart
- Barret Valerie
- Bartke Jerzy
- Basile M.
- Bastid Nicole
- Basu Sumit
- Bathen B.
- Batigne Guillaume
- Batista Camejo A.
- Batyunya Boris
- Batzing P.C.
- Baumann C.
- Bearden Ian Gardner
- Beck H.
- Bedda Cristina
- Behera N.K.
- Belikov I.
- Bellini F.
- Bellwied Rene
- Belmont R.
- Belmont-Moreno E.
- Belyaev V.
- Bencedi G.
- Beole S.
- Berceanu I.
- Bercuci A.
- Berdnikov Y.
- Berenyi D.
- Berger M.E.
- Bertens Redmer Alexander
- Berzano D.
- Betev Latchezar
- Bhasin Anju
- Bhat I.R.
- Bhati A.K.
- Bhattacharjee Buddhadeb
- Bhom J.
- Bianchi L.
- Bianchi N.
- Bianchin Chiara
- Bielčík Jaroslav
- Bielčíková Jana
- Bilandzic A.
- Bjelogrlic S.
- Blanco F.
- Blau Dmitry S.
- Blume Christoph
- Bock Friederike
- Bogdanov Alexey A.
- Bogolyubsky M.
- Boldizsár László
- Bombara Marek
- Book J.
- Borel Hervé
- Borissov Alexander
- Bossú F.
- Botje Michiel
- Botta Elena
- Braun-Munzinger Peter
- Bregant Marco
- Breitner T.
- Broker Theo Alexander
- Browning T.A.
- Broz Michal
- Bruna Elena
- Bruno Giuseppe Eugenio
- Budnikov Dmitry
- Bufalino Stefania
- Bunčić Predrag
- Busch Oliver
- Buthelezi Edith Zinhle
- Böhmer F.V.
- Böttger S.
- Bøggild H.
- Büsching Henner
- Caffarri Davide
- Cai Xiao
- Caines Helen Louise
- Calero Diaz L.
- Caliva Alberto
- Calvo Villar Ernesto
- Camerini Paolo
- Carena Francesco
- Carena Wisla
- Casula Ester Anna Rita
- Catanescu V.
- Cavicchioli C.
- Ceballos Sanchez Cesar
- Cepila J.
- Cerello P.
- Chang Beom-Su
- Chapeland Sylvain
- Charvet J.L.
- Chattopadhyay S.
- Chattopadhyay S.
- Chelnokov Volodymyr
- Cherney Michael Gerard
- Cheshkov Cvetan Valeriev
- Cheynis Brigitte
- Chibante Barroso Vasco Miguel
- Chinellato David Dobrigkeit
- Chochula Peter
- Chojnacki M.
- Choudhury Subikash
- Christakoglou Panagiotis
- Christensen Christian Holm
- Christiansen Peter L.
- Chujo Tatsuya
- Chung Suh-Urk
- Cicalò Corrado
- Cifarelli Luisa
- Cindolo Federico
- Cleymans Jean Willy Andre
- Colamaria Fabio Filippo
- Colella Domenico
- Collu Alberto
- Colocci Manuel
- Conesa Balbastre Gustavo
- Conesa del Valle Zaida
- Connors M.E.
- Contreras Nuno Jesus Guillermo
- Cormier Thomas Michael
- Corrales Morales Yasser
- Cortese Pietro
- Cortés Maldonado I.
- Cosentino Mauro Rogerio
- Costa Filippo
- Crochet Philippe
- Cruz Albino R.
- Cuautle Flores Eleazar
- Cunqueiro Mendez Leticia
- Cuveland Jan de
- Dainese Andrea
- Dang R.
- Danu Andrea
- Das Debasish
- Das Indranil
- Das K.
- Das Supriya
- Dash Ajay Kumar
- Dash Sadhana
- De Caro Annalisa
- De Cataldo Giacinto
- De Falco Alessandro
- De Gruttola Daniele
- De Marco Nora
- De Pasquale Salvatore
- de Rooij R.
- De Sudipan
- Delagrange H.
- Deloff Andrzej
- Di Bari Domenico
- Di Liberto S.
- Di Mauro A.
- Di Nezza P.
- Diaz Corchero Miguel Angel
- Dietel Thomas
- Dillenseger Pascal
- Divià R.
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- Dobrin A.
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- Domenicis Gimenez D.
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- Dørheim S.
- D’Erasmo G.
- Ehlers Raymond James
- Elia Domenico
- Engel Heiko
- Erazmus Barbara Ewa
- Erdal H.A.
- Eschweiler D.
- Espagnon Bruno
- Esposito M.
- Estienne Magali Danielle
- Esumi S.
- Evans David
- Evdokimov Sergey
- Fabris D.
- Faivre Julien
- Falchieri D.
- Fantoni Alessandra
- Fasel Markus
- Fehlker D.
- Feldkamp Linus
- Felea D.
- Feliciello Alessandro
- Feofilov Grigori A.
- Ferencei J.
- Fernández Téllez Arturo
- Ferreiro E.G.
- Ferretti Alessandro
- Festanti Andrea
- Figiel Jan
- Figueredo Marcel Araujo Silva
- Filchagin Sergey
- Finogeev Dmitry
- Fionda Fiorella Maria Celeste
- Fiore E.M.
- Floratos E.
- Floris Michele
- Foertsch Siegfried Valentin
- Foka Panagiota
- Fokin Sergey
- Fragiacomo Enrico
- Francescon Andrea
- Frankenfeld Ulrich
- Fuchs Ulrich
- Furget Christophe
- Fusco Girard Mario
- Gaardhøje Jens Jørgen
- Gagliardi Martino
- Gago A.M.
- Gallio M.
- Gangadharan D.R.
- Ganoti P.
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- Viinikainen Jussi Samuli
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- Vinogradov Alexander A.
- Vinogradov Leonid
- Vinogradov Y.
- Virgili Tiziano
- Viyogi Y.P.
- Vodopyanov Alexander
- Voloshin Kirill
- Voloshin Sergei
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- Vorobyev Ivan
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- Völkl Martin Andreas
- Wagner Boris
- Wagner J.
- Wagner V.
- Wang M.
- Wang Y.
- Watanabe Daisuke
- Weber Michael
- Wessels Johannes P.
- Westerhoff Uwe
- Wiechula Jens
- Wikne Jon
- Wilde M.
- Wilk Grzegorz Andrzej
- Wilkinson Jeremy
- Williams M.C.S.
- Windelband Bernd
- Winn M.
- Yaldo Chris G.
- Yamaguchi Y.
- Yang H.
- Yang Ping
- Yang S.
- Yano Satoshi
- Yasnopolskiy S.
- Yi J.
- Yin Zhongbao
- Yoo In-Kwon
- Yushmanov I.
- Zaccolo Valentina
- Zach C.
- Zaman Ali
- Zampolli Chiara
- Zaporozhets S.
- Zarochentsev Andrey
- Zaviyalov Nikolaj
- Zbroszczyk Hanna Paulina
- Zgura I.S.
- Zhalov Mikhail
- Zhang Haitao
- Zhang Xiaoming
- Zhang Y.
- Zhao C.
- Zhigareva Natalia
- Zhou Daicui
- Zhou F.
- Zhou You
- Zhou Zhuo
- Zhu Hongsheng
- Zhu Jianhui
- Zhu X.
- Zichichi Antonino
- Zimmermann A.
- Zimmermann Markus Bernhard
- Zinovjev Gennady M.
- Zoccarato Y.
- Zyzak Maksym
- Závada Petr
- Šafařík Karel
- Šumbera Michal
- Šuša Tatjana
- Šándor L.
- Publication venue
- 'Elsevier BV'
- Publication date
- 16/05/2014
- Field of study
The ALICE Collaboration at the LHC reports measurement of the inclusive production cross section of electrons from semi-leptonic decays of beauty hadrons with rapidity |y| < 0.8 and transverse momentum 1 < pT < 10 GeV/c, in pp collisions at √s = 2.76 TeV. Electrons not originating from semi-electronic decay of beauty hadrons are suppressed using the impact parameter of the corresponding tracks. The production cross section of beauty decay electrons is compared to the result obtained with an alternative method which uses the distribution of the azimuthal angle between heavy-flavour decay electrons and charged hadrons. Perturbative QCD predictions agree with the measured cross section within the experimental and theoretical uncertainties. The integrated visible cross section, σb→e = 3.47 ± 0.40(stat) +1.12 −1.33(sys) ± 0.07(norm) μb, was extrapolated to full phase space using Fixed Order plus Next-to-Leading Log (FONLL) calculations to obtain the total bb production ¯ cross section, σbb¯ = 130 ± 15.1(stat) +42.1 −49.8(sys) +3.4 −3.1(extr) ± 2.5(norm) ± 4.4(BR) μb