102 research outputs found
A systematic fitting scheme for caustic-crossing microlensing events
We outline a method for fitting binary-lens caustic-crossing microlensing
events based on the alternative model parameterisation proposed and detailed in
Cassan (2008). As an illustration of our methodology, we present an analysis of
OGLE-2007-BLG-472, a double-peaked Galactic microlensing event with a source
crossing the whole caustic structure in less than three days. In order to
identify all possible models we conduct an extensive search of the parameter
space, followed by a refinement of the parameters with a Markov Chain-Monte
Carlo algorithm. We find a number of low-chi2 regions in the parameter space,
which lead to several distinct competitive best models. We examine the
parameters for each of them, and estimate their physical properties. We find
that our fitting strategy locates several minima that are difficult to find
with other modelling strategies and is therefore a more appropriate method to
fit this type of events.Comment: 12 pages, 11 figure
Limits on additional planetary companions to OGLE-2005-BLG-390L
We investigate constraints on additional planets orbiting the distant M-dwarf
star OGLE-2005-BLG-390L, around which photometric microlensing data has
revealed the existence of the sub-Neptune-mass planet OGLE-2005-BLG-390Lb. We
specifically aim to study potential Jovian companions and compare our findings
with predictions from core-accretion and disc-instability models of planet
formation. We also obtain an estimate of the detection probability for
sub-Neptune mass planets similar to OGLE-2005-BLG-390Lb using a simplified
simulation of a microlensing experiment. We compute the efficiency of our
photometric data for detecting additional planets around OGLE-2005-BLG-390L, as
a function of the microlensing model parameters and convert it into a function
of the orbital axis and planet mass by means of an adopted model of the Milky
Way. We find that more than 50 % of potential planets with a mass in excess of
1 M_J between 1.1 and 2.3 AU around OGLE-2005-BLG-390L would have revealed
their existence, whereas for gas giants above 3 M_J in orbits between 1.5 and
2.2 AU, the detection efficiency reaches 70 %; however, no such companion was
observed. Our photometric microlensing data therefore do not contradict the
existence of gas giant planets at any separation orbiting OGLE-2005-BLG-390L.
Furthermore we find a detection probability for an OGLE-2005-BLG-390Lb-like
planet of around 2-5 %. In agreement with current planet formation theories,
this quantitatively supports the prediction that sub-Neptune mass planets are
common around low-mass stars.Comment: 10 pages, 4 figures, accepted by A&
OGLE-2005-BLG-018: Characterization of Full Physical and Orbital Parameters of a Gravitational Binary Lens
We present the analysis result of a gravitational binary-lensing event
OGLE-2005-BLG-018. The light curve of the event is characterized by 2 adjacent
strong features and a single weak feature separated from the strong features.
The light curve exhibits noticeable deviations from the best-fit model based on
standard binary parameters. To explain the deviation, we test models including
various higher-order effects of the motions of the observer, source, and lens.
From this, we find that it is necessary to account for the orbital motion of
the lens in describing the light curve. From modeling of the light curve
considering the parallax effect and Keplerian orbital motion, we are able to
measure not only the physical parameters but also a complete orbital solution
of the lens system. It is found that the event was produced by a binary lens
located in the Galactic bulge with a distance kpc from the Earth.
The individual lens components with masses and are separated with a semi-major axis of AU and
orbiting each other with a period yr. The event demonstrates
that it is possible to extract detailed information about binary lens systems
from well-resolved lensing light curves.Comment: 19 pages, 6 figure
OGLE-2005-BLG-071Lb, the Most Massive M-Dwarf Planetary Companion?
We combine all available information to constrain the nature of
OGLE-2005-BLG-071Lb, the second planet discovered by microlensing and the first
in a high-magnification event. These include photometric and astrometric
measurements from Hubble Space Telescope, as well as constraints from higher
order effects extracted from the ground-based light curve, such as microlens
parallax, planetary orbital motion and finite-source effects. Our primary
analysis leads to the conclusion that the host of Jovian planet
OGLE-2005-BLG-071Lb is an M dwarf in the foreground disk with mass M= 0.46 +/-
0.04 Msun, distance D_l = 3.3 +/- 0.4 kpc, and thick-disk kinematics v_LSR ~
103 km/s. From the best-fit model, the planet has mass M_p = 3.8 +/- 0.4 M_Jup,
lies at a projected separation r_perp = 3.6 +/- 0.2 AU from its host and so has
an equilibrium temperature of T ~ 55 K, i.e., similar to Neptune. A degenerate
model less favored by \Delta\chi^2 = 2.1 (or 2.2, depending on the sign of the
impact parameter) gives similar planetary mass M_p = 3.4 +/- 0.4 M_Jup with a
smaller projected separation, r_\perp = 2.1 +/- 0.1 AU, and higher equilibrium
temperature T ~ 71 K. These results from the primary analysis suggest that
OGLE-2005-BLG-071Lb is likely to be the most massive planet yet discovered that
is hosted by an M dwarf. However, the formation of such high-mass planetary
companions in the outer regions of M-dwarf planetary systems is predicted to be
unlikely within the core-accretion scenario. There are a number of caveats to
this primary analysis, which assumes (based on real but limited evidence) that
the unlensed light coincident with the source is actually due to the lens, that
is, the planetary host. However, these caveats could mostly be resolved by a
single astrometric measurement a few years after the event.Comment: 51 pages, 12 figures, 3 tables, Published in Ap
Binary microlensing event OGLE-2009-BLG-020 gives a verifiable mass, distance and orbit predictions
We present the first example of binary microlensing for which the parameter
measurements can be verified (or contradicted) by future Doppler observations.
This test is made possible by a confluence of two relatively unusual
circumstances. First, the binary lens is bright enough (I=15.6) to permit
Doppler measurements. Second, we measure not only the usual 7 binary-lens
parameters, but also the 'microlens parallax' (which yields the binary mass)
and two components of the instantaneous orbital velocity. Thus we measure,
effectively, 6 'Kepler+1' parameters (two instantaneous positions, two
instantaneous velocities, the binary total mass, and the mass ratio). Since
Doppler observations of the brighter binary component determine 5 Kepler
parameters (period, velocity amplitude, eccentricity, phase, and position of
periapsis), while the same spectroscopy yields the mass of the primary, the
combined Doppler + microlensing observations would be overconstrained by 6 + (5
+ 1) - (7 + 1) = 4 degrees of freedom. This makes possible an extremely strong
test of the microlensing solution. We also introduce a uniform microlensing
notation for single and binary lenses, we define conventions, summarize all
known microlensing degeneracies and extend a set of parameters to describe full
Keplerian motion of the binary lenses.Comment: 51 pages, 8 figures, 2 appendices. Submitted to ApJ. Fortran codes
for Appendix B are attached to this astro-ph submission and are also
available at http://www.astronomy.ohio-state.edu/~jskowron/OGLE-2009-BLG-020
Multicenter Evaluation of a Novel Surveillance Paradigm for Complications of Mechanical Ventilation
Ventilator-associated pneumonia (VAP) surveillance is time consuming, subjective, inaccurate, and inconsistently predicts outcomes. Shifting surveillance from pneumonia in particular to complications in general might circumvent the VAP definition's subjectivity and inaccuracy, facilitate electronic assessment, make interfacility comparisons more meaningful, and encourage broader prevention strategies. We therefore evaluated a novel surveillance paradigm for ventilator-associated complications (VAC) defined by sustained increases in patients' ventilator settings after a period of stable or decreasing support.We assessed 600 mechanically ventilated medical and surgical patients from three hospitals. Each hospital contributed 100 randomly selected patients ventilated 2-7 days and 100 patients ventilated >7 days. All patients were independently assessed for VAP and for VAC. We compared incidence-density, duration of mechanical ventilation, intensive care and hospital lengths of stay, hospital mortality, and time required for surveillance for VAP and for VAC. A subset of patients with VAP and VAC were independently reviewed by a physician to determine possible etiology.Of 597 evaluable patients, 9.3% had VAP (8.8 per 1,000 ventilator days) and 23% had VAC (21.2 per 1,000 ventilator days). Compared to matched controls, both VAP and VAC prolonged days to extubation (5.8, 95% CI 4.2-8.0 and 6.0, 95% CI 5.1-7.1 respectively), days to intensive care discharge (5.7, 95% CI 4.2-7.7 and 5.0, 95% CI 4.1-5.9), and days to hospital discharge (4.7, 95% CI 2.6-7.5 and 3.0, 95% CI 2.1-4.0). VAC was associated with increased mortality (OR 2.0, 95% CI 1.3-3.2) but VAP was not (OR 1.1, 95% CI 0.5-2.4). VAC assessment was faster (mean 1.8 versus 39 minutes per patient). Both VAP and VAC events were predominantly attributable to pneumonia, pulmonary edema, ARDS, and atelectasis.Screening ventilator settings for VAC captures a similar set of complications to traditional VAP surveillance but is faster, more objective, and a superior predictor of outcomes
AGAPEROS: Searches for microlensing in the LMC with the Pixel Method; 2, Selection of possible microlensing events
We apply the pixel method of analysis (sometimes called ``pixel lensing'') to a small subset of the EROS-1 microlensing observations of the bar of the Large Magellanic Cloud (LMC). The pixel method is designed to find microlensing events of unresolved source stars and had heretofore been applied only to M31 where essentially all sources are unresolved. With our analysis optimised for the detection of long-duration microlensing events due to 0.01-1 Mo Machos, we detect no microlensing events and compute the corresponding detection efficiencies. We show that the pixel method should detect 10 to 20 times more microlensing events for M>0.05 Mo Machos compared to a classical analysis of the same data which latter monitors only resolved stars. In particular, we show that for a full halo of Machos in the mass range 0.1 -- 0.5 Mo, a pixel analysis of the three-year EROS-1 data set covering 0.39 deg^2 would yield 4 events.We apply the pixel method of analysis (sometimes called ''pixel lensing'') to a small subset of the EROS-1 microlensing observations of the bar of the Large Magellanic Cloud (LMC). The pixel method is designed to find microlensing events of unresolved source stars and had heretofore been applied only to M31 where essentially all sources are unresolved. With our analysis optimised for the detection of long-duration microlensing events due to 0.01-1 Mo Machos, we detect no microlensing events and compute the corresponding detection efficiencies. We show that the pixel method, applied to crowded fields, should detect 10 to 20 times more microlensing events for M>0.05 Mo Machos compared to a classical analysis of the same data which latter monitors only resolved stars. In particular, we show that for a full halo of Machos in the mass range 0.1-0.5 M , a pixel analysis of the three-year EROS-1 data set covering would yield events
AGAPEROS: Searches for microlensing in the LMC with the Pixel Method; 1, Data treatment and pixel light curves production
The presence and abundance of MAssive Compact Halo Objects (MACHOs) towards the Large Magellanic Cloud (LMC) can be studied with microlensing searches. The 10 events detected by the EROS and MACHO groups suggest that objects with 0.5 Mo could fill 50% of the dark halo. This preferred mass is quite surprising, and increasing the presently small statistics is a crucial issue. Additional microlensing of stars too dim to be resolved in crowded fields should be detectable using the Pixel Method. We present here an application of this method to the EROS 91-92 data (one tenth of the whole existing data set). We emphasize the data treatment required for monitoring pixel fluxes. Geometric and photometric alignments are performed on each image. Seeing correction and error estimates are discussed. 3.6" x 3.6" super-pixel light curves, thus produced, are very stable over the 120 days time-span. Fluctuations at a level of 1.8% of the flux in blue and 1.3% in red are measured on the pixel light curves. This level of stability is comparable with previous estimates. The data analysis dedicated to the search of possible microlensing events together with refined simulations will be presented in a companion paper.Recent surveys monitoring millions of light curves of resolved stars in the LMC have discovered several microlensing events. Unresolved stars could however significantly contribute to the microlensing rate towards the LMC. Monitoring pixels, as opposed to individual stars, should be able to detect stellar variability as a variation of the pixel flux. We present a first application of this new type of analysis (Pixel Method) to the LMC Bar. We describe the complete procedure applied to the EROS 91-92 data (one tenth of the existing CCD data set) in order to monitor pixel fluxes. First, geometric and photometric alignments are applied to each images. Averaging the images of each night reduces significantly the noise level. Second, one light curve for each of the 2.1 10^6 pixels is built and pixels are lumped into 3.6"x3.6" super-pixels, one for each elementary pixel. An empirical correction is then applied to account for seeing variations. We find that the final super-pixel light curves fluctuate at a level of 1.8% of the flux in blue and 1.3% in red. We show that this noise level corresponds to about twice the expected photon noise and confirms previous assumptions used for the estimation of the contribution of unresolved stars. We also demonstrate our ability to correct very efficiently for seeing variations affecting each pixel flux. The technical results emphasised here show the efficacy of the Pixel Method and allow us to study luminosity variations due to possible microlensing events and variable stars in two companion papers
Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity
Patients with chronic lung disease (CLD) have an increased risk for severe coronavirus disease-19 (COVID-19) and poor outcomes. Here, we analyze the transcriptomes of 611,398 single cells isolated from healthy and CLD lungs to identify molecular characteristics of lung cells that may account for worse COVID-19 outcomes in patients with chronic lung diseases. We observe a similar cellular distribution and relative expression of SARS-CoV-2 entry factors in control and CLD lungs. CLD AT2 cells express higher levels of genes linked directly to the efficiency of viral replication and the innate immune response. Additionally, we identify basal differences in inflammatory gene expression programs that highlight how CLD alters the inflammatory microenvironment encountered upon viral exposure to the peripheral lung. Our study indicates that CLD is accompanied by changes in cell-type-specific gene expression programs that prime the lung epithelium for and influence the innate and adaptive immune responses to SARS-CoV-2 infection
A giant planet beyond the snow line in microlensing event OGLE-2011-BLG-0251
Aims: We present the analysis of the gravitational microlensing event OGLE-2011-BLG-0251. This anomalous event was observed by several survey and follow-up collaborations conducting microlensing observations towards the Galactic bulge. Methods: Based on detailed modelling of the observed light curve, we find that the lens is composed of two masses with a mass ratio q = 1.9 Ă 10[SUP]-3[/SUP]. Thanks to our detection of higher-order effects on the light curve due to the Earth's orbital motion and the finite size of source, we are able to measure the mass and distance to the lens unambiguously. Results: We find that the lens is made up of a planet of mass 0.53 ± 0.21 M[SUB]J[/SUB] orbiting an M dwarf host star with a mass of 0.26 ± 0.11 M[SUB]â[/SUB]. The planetary system is located at a distance of 2.57 ± 0.61 kpc towards the Galactic centre. The projected separation of the planet from its host star is d = 1.408 ± 0.019, in units of the Einstein radius, which corresponds to 2.72 ± 0.75 AU in physical units. We also identified a competitive model with similar planet and host star masses, but with a smaller orbital radius of 1.50 ± 0.50 AU. The planet is therefore located beyond the snow line of its host star, which we estimate to be around ~1-1.5 AU
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