120 research outputs found

    Estimation de la réponse impulsionnelle spatiale d'un systÚme d'optique adaptative à partir des données de contrÎle de boucle

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    Nous proposons une nouvelle mĂ©thode permettant d'estimer la rĂ©ponse impulsionnelle spatiale d'un systĂšme d'optique adaptative pour l'astronomie. Celle-ci dĂ©pend fortement des conditions d'acquisition et sa connaissance est essentielle afin de pouvoir amĂ©liorer, Ă  l'aide d'algorithmes de dĂ©convolution, le contraste des images acquises. La mĂ©thode proposĂ©e est plus prĂ©cise que les mĂ©thodes habituellement mises en oeuvre car elle se base sur des donnĂ©es parfaitement synchrones avec l'acquisition. De plus, elle n'occasionne pas de perte de temps d'observation. Sur le TĂ©lescope Canada-France-Hawaii, de trĂšs bons rĂ©sultats ont pu ĂȘtre obtenus, pour des sources de rĂ©fĂ©rence de magnitude infĂ©rieure ou Ă©gale Ă  13

    Concepts, Modélisation et Commandes des Hydroliennes

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    Face au problĂšme de la gestion des dĂ©chets nuclĂ©aire et aux Ă©missions de gaz Ă  effet de serre, les Ă©nergies renouvelables occupent une place avancĂ©e parmi les Ă©nergies d’avenir grĂące Ă  leur faible impact sur l’environnement ; d’autant plus que ces Ă©nergies jouent un rĂŽle important dans la lutte contre le changement climatique et dans le dĂ©veloppement Ă©conomique de certains pays. Ces atouts, alliĂ©s Ă  des technologies de plus en plus performantes, favorisent le dĂ©veloppement des Ă©nergies renouvelables mais de maniĂšre encore trĂšs inĂ©gale selon le type de ressources considĂ©rĂ©es. Une de ces Ă©nergies renouvelables, l’énergie hydrolienne, suscite depuis quelques annĂ©es un intĂ©rĂȘt particulier du fait de ses nombreux avantages. En effet, la force et la vitesse des courants de marĂ©e, phĂ©nomĂšne prĂ©dictible, peuvent ĂȘtre connues des dĂ©cennies Ă  l’avance. Pour une hydrolienne placĂ©e Ă  un endroit donnĂ©, il est donc possible, par opposition aux autres Ă©nergies renouvelables, dĂ©pendant des conditions mĂ©tĂ©orologiques, de connaĂźtre Ă  tout moment quelle sera, au premier ordre, la puissance extractible par les gestionnaires de rĂ©seaux d’énergie afin d’alimenter ses consommateurs. De plus, les pays d’Europe de l’Ouest et en particulier le Royaume Uni et la France possĂšdent de nombreux sites prĂšs des cotes ou cette Ă©nergie est exploitable dans de bonnes conditions Ă©conomiques. Le but de chapitre est la prĂ©sentation succincte des principaux concepts hydroliens puis de donner des Ă©lĂ©ments quant Ă  la modĂ©lisation d’un concept de base, et enfin introduire des Ă©lĂ©ments de contrĂŽle/command

    Pushing the precision frontier at the LHC with V+jets

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    This documents the proceedings from a workshop titled `Illuminating Standard candles at the LHC: V+jets' held at Imperial College London on 25th-26th April 2017. It summarises the numerous contributions to the workshop, from the experimental overview of V+jets measurements at CMS and ATLAS and their role in searching for physics beyond the Standard Model to the status of higher order perturbative calculations to these processes and their inclusion in state of the art Monte Carlo simulations. An executive summary of the ensuing discussions including a list of outcomes and wishlist for future consideration is also presented

    Genome-Wide Linkage in a Highly Consanguineous Pedigree Reveals Two Novel Loci on Chromosome 7 for Non-Syndromic Familial Premature Ovarian Failure

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    BACKGROUND: The human condition known as Premature Ovarian Failure (POF) is characterized by loss of ovarian function before the age of 40. A majority of POF cases are sporadic, but 10-15% are familial, suggesting a genetic origin of the disease. Although several causal mutations have been identified, the etiology of POF is still unknown for about 90% of the patients.ŠMETHODOLOGY/PRINCIPAL FINDINGS: We report a genome-wide linkage and homozygosity analysis in one large consanguineous Middle-Eastern POF-affected family presenting an autosomal recessive pattern of inheritance. We identified two regions with a LOD(max) of 3.26 on chromosome 7p21.1-15.3 and 7q21.3-22.2, which are supported as candidate regions by homozygosity mapping. Sequencing of the coding exons and known regulatory sequences of three candidate genes (DLX5, DLX6 and DSS1) included within the largest region did not reveal any causal mutations.ŠCONCLUSIONS/SIGNIFICANCE: We detect two novel POF-associated loci on human chromosome 7, opening the way to the identification of new genes involved in the control of ovarian development and function

    Stronger and More Vulnerable: A Balanced View of the Impacts of the NICU Experience on Parents

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    For parents, the experience of having an infant in the NICU is often psychologically traumatic. No parent can be fully prepared for the extreme stress and range of emotions of caring for a critically ill newborn. As health care providers familiar with the NICU, we thought that we understood the impact of the NICU on parents. But we were not prepared to see the children in our own families as NICU patients. Here are some of the lessons our NICU experience has taught us. We offer these lessons in the hope of helping health professionals consider a balanced view of the NICU's impact on families

    Genome-Wide Linkage in a Highly Consanguineous Pedigree Reveals Two Novel Loci on Chromosome 7 for Non-Syndromic Familial Premature Ovarian Failure

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    Background: The human condition known as Premature Ovarian Failure (POF) is characterized by loss of ovarian function before the age of 40. A majority of POF cases are sporadic, but 10–15% are familial, suggesting a genetic origin of the disease. Although several causal mutations have been identified, the etiology of POF is still unknown for about 90% of the patients. Methodology/Principal Findings: We report a genome-wide linkage and homozygosity analysis in one large consanguineous Middle-Eastern POF-affected family presenting an autosomal recessive pattern of inheritance. We identified two regions with a LODmax of 3.26 on chromosome 7p21.1-15.3 and 7q21.3-22.2, which are supported as candidate regions by homozygosity mapping. Sequencing of the coding exons and known regulatory sequences of three candidate genes (DLX5, DLX6 and DSS1) included within the largest region did not reveal any causal mutations. Conclusions/Significance: We detect two novel POF-associated loci on human chromosome 7, opening the way to the identification of new genes involved in the control of ovarian development and function

    Exploring manycore architectures for next-generation HPC systems through the MANGO approach

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    [EN] The Horizon 2020 MANGO project aims at exploring deeply heterogeneous accelerators for use in High-Performance Computing systems running multiple applications with different Quality of Service (QoS) levels. The main goal of the project is to exploit customization to adapt computing resources to reach the desired QoS. For this purpose, it explores different but interrelated mechanisms across the architecture and system software. In particular, in this paper we focus on the runtime resource management, the thermal management, and support provided for parallel programming, as well as introducing three applications on which the project foreground will be validated.This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 671668.Flich Cardo, J.; Agosta, G.; Ampletzer, P.; Atienza-Alonso, D.; Brandolese, C.; Cappe, E.; Cilardo, A.... (2018). Exploring manycore architectures for next-generation HPC systems through the MANGO approach. Microprocessors and Microsystems. 61:154-170. https://doi.org/10.1016/j.micpro.2018.05.011S1541706

    Magmatic processes in developing oceanic crust revealed in a cumulate xenolith collected at the East Pacific Rise, 9°50â€ČN

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    Author Posting. © American Geophysical Union, 2006. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geochemistry Geophysics Geosystems 7 (2006): Q12O04, doi:10.1029/2006GC001316.The petrology and geochemistry of a xenolith, a fragment of a melt-bearing cumulate, within a recently erupted mid-ocean ridge (MOR) lava flow provide information on petrogenetic processes occurring within the newly forming oceanic crust beneath the northern East Pacific Rise (NEPR). The xenolith reveals important petrologic information about MOR magmatic systems concerning (1) melt distribution in a crystal-dominated mush; (2) melt-crystal reactions within the mush; (3) the chemistry of melts that have contributed to the cumulate lithology; and (4) the chemistry of axial melts that enter the axial magma system. The xenolith was enclosed within a moderately primitive, normal mid-ocean ridge basalt (NMORB) erupted in 1991 within the neovolcanic zone of the NEPR, at approximately 9°50â€ČN. The sample is a matrix-dominated, cumulate olivine anorthosite, composed of anorthite (An94-90) and bytownite (An89-70), intergranular olivine (Fo86±0.3), minor sulfide and spinel, and intergranular glass. Marginal corrosion of plagioclase, and possibly olivine, and internal remelting of plagioclase indicate syntexis. It is surmised that the pore volume was eviscerated several times with moderately primitive basaltic melts and reduced by intergranular crystallization of forsteritic olivine. The presence of anorthite as a cumulate phase in the xenolith and the observation of anorthite xenocrysts in NMORB lavas, and as a cumulate phase in ophiolite gabbros, indicate that Ca-rich melts that are not a part of the NMORB lineage play an important role in the construction of the oceanic crust.The Mineral Resources Program, USGS, provided support to W.I.R. for this research. Field and laboratory research was supported by NSF grants OCE-9402360, 9403773, and 0138088 to M.R.P. and NSF grants OCE-9819261 and OCE-0525863 to D.J.F
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