Fingerprint Identification Using Noise in the Horizontal-to-Vertical Spectral Ratio: Retrieving the Impedance Contrast Structure for the Almaty Basin (Kazakhstan)

Detailed knowledge of the 3D basin structure underlying urban areas is of major importance for improving the assessment of seismic hazard and risk. However, mapping the major features of the shallow geological layers becomes expensive where large areas need to be covered. In this study, we propose an innovative tool, based mainly on single station noise recordings and the horizontal-to-vertical spectral ratio (H/V), to identify and locate the depth of major impedance contrasts. The method is based on an identification of so-called fingerprints of the major impedance discontinuities and their migration to depth by means of an analytical procedure. The method is applied to seismic noise recordings collected in the city of Almaty (Kazakhstan). The estimated impedance contrasts vs. depth profiles are interpolated in order to derive a three-dimensional (3D) model, which after calibration with some available boreholes data allows the major tectonic features in the subsurface to be identified

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008

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Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen).

Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an IgE-mediated inflammation of the membranes lining the nose. It is a global health problem that causes major illness and disability worldwide. Over 600 million patients from all countries, all ethnic groups and of all ages suffer from allergic rhinitis. It affects social life, sleep, school and work and its economic impact is substantial. Risk factors for allergic rhinitis are well identified. Indoor and outdoor allergens as well as occupational agents cause rhinitis and other allergic diseases. The role of indoor and outdoor pollution is probably very important, but has yet to be fully understood both for the occurrence of the disease and its manifestations. In 1999, during the Allergic Rhinitis and its Impact on Asthma (ARIA) WHO workshop, the expert panel proposed a new classification for allergic rhinitis which was subdivided into _intermittent_ or _persistent_ disease. This classification is now validated. The diagnosis of allergic rhinitis is often quite easy, but in some cases it may cause problems and many patients are still under-diagnosed, often because they do not perceive the symptoms of rhinitis as a disease impairing their social life, school and work. The management of allergic rhinitis is well established and the ARIA expert panel based its recommendations on evidence using an extensive review of the literature available up to December 1999. The statements of evidence for the development of these guidelines followed WHO rules and were based on those of Shekelle et al. A large number of papers have been published since 2000 and are extensively reviewed in the 2008 Update using the same evidence-based system. Recommendations for the management of allergic rhinitis are similar in both the ARIA workshop report and the 2008 Update. In the future, the GRADE approach will be used, but is not yet available. Another important aspect of the ARIA guidelines was to consider co-morbidities. Both allergic rhinitis and asthma are systemic inflammatory conditions and often co-exist in the same patients. In the 2008 Update, these links have been confirmed. TheARIAdocument is not intended to be a standard-ofcare document for individual countries. It is provided as a basis for physicians, health care professionals and organizations involved in the treatment of allergic rhinitis and asthma in various countries to facilitate the development of relevant local standard-of-care documents for patients

Development and implementation of guidelines in allergic rhinitis - an ARIA-GA2LEN paper

Contains fulltext : 88489.pdf (Publisher’s version ) (Closed access

Severe chronic allergic (and related) diseases:a uniform approach - A MeDALL - GA(2)LEN - ARIA position paper

Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies