49 research outputs found

    ATLAS Pixel Module Assembly in Dortmund

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    The ATLAS Pixel detector is the inner- most substructure of the multi-purpose LHC ex- periment ATLAS at CERN and part of the track- ing system. The Pixel vertex system will consist of 1744 hybrid pixel modules, about 280 of them have been assembled at the University of Dortmund. This work provides a detailed description of the ATLAS Pixel module assembly procedure executed at the University of Dortmund. Effort had been put into the developement of a laboratory and testing environment to fulfill all technical demands of a se- rial production of fully efficent pixel modules

    The psychopathological and psychosocial outcome of early-onset schizophrenia: Preliminary data of a 13-year follow-up

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    <p>Abstract</p> <p>Background</p> <p>Relatively little is known about the long-term psychopathological and psychosocial outcome of early-onset schizophrenia. The existing literature describes more severe courses of illness in these patients compared with adult-onset schizophrenia. This article reports preliminary data of a study exploring the outcome of early-onset schizophrenia 13.4 years (mean) after first admission. Predictors for interindividual outcomes were investigated.</p> <p>Methods</p> <p>We retrospectively assessed 27 former patients (mean age at first admission 15.5 years, SD = 2.0) that were consecutively admitted to the Department of Child and Adolescent Psychiatry at the University of Wuerzburg between 1990 and 2000. A multidimensional approach was chosen to assess the outcome consisting of a mail survey including different questions about psychopathological symptoms, psychosocial parameters, and standardized self-reports (ESI and ADS).</p> <p>Results</p> <p>Concerning the psychopathological outcome, 22.2% reported having acute schizophrenic symptoms. Almost one third (30.8%) described symptoms of depression and 37.0% reported having tried to commit suicide or seriously thought about it. 77.8% of the former patients were still in outpatient treatment. Compared to the general population, the number of patients without a school graduation was relatively high (18.5%). Almost half of participants still live with their parents (48.1%) or in assisted or semi-assisted living conditions (33.3%). Only 18.5% were working in the open market.</p> <p>Conclusion</p> <p>Schizophrenia with an early onset has an unfavourable prognosis. Our retrospective study of the psychopathological and psychosocial outcome concludes with a generally poor rating.</p

    Measurement of the production cross section for W-bosons in association with jets in pp collisions at s=7 TeV with the ATLAS detector

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    ATLAS pixel detector electronics and sensors

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    The silicon pixel tracking system for the ATLAS experiment at the Large Hadron Collider is described and the performance requirements are summarized. Detailed descriptions of the pixel detector electronics and the silicon sensors are given. The design, fabrication, assembly and performance of the pixel detector modules are presented. Data obtained from test beams as well as studies using cosmic rays are also discussed

    Charged-particle multiplicities in pp interactions at root s=900 GeV measured with the ATLAS detector at the LHC ATLAS Collaboration

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    The first measurements from proton–proton collisions recorded with the ATLAS detector at the LHC are presented. Data were collected in December 2009 using a minimum-bias trigger during collisions at a centre-of-mass energy of 900 GeV. The charged-particle multiplicity, its dependence on transverse momentum and pseudorapidity, and the relationship between mean transverse momentum and charged-particle multiplicity are measured for events with at least one charged particle in the kinematic range |η|500 MeVpT>500 MeV. The measurements are compared to Monte Carlo models of proton–proton collisions and to results from other experiments at the same centre-of-mass energy. The charged-particle multiplicity per event and unit of pseudorapidity at η=0η=0 is measured to be 1.333±0.003(stat.)±0.040(syst.)1.333±0.003(stat.)±0.040(syst.), which is 5–15% higher than the Monte Carlo models predict

    Fig S1-7 All Supplemental Figures

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    Figure S1. Setup of developmental slices, enzyme/metabolite data deconvolution method, and validation of separation method. Figure S2. Metabolite levels in BS and M of the developmental slices (full data in dataset S1). Figure S3. Contextual data of developmental section pairing, and library complexity for inter-study comparison. Figure S4. Transcript coverage of genes (or their orthologs) that were significantly enriched in the BS in Chang_2012, but in M in here Denton_2016. Figure S5. Transcript coverage of examples genes from conflict set 1 (definition and gene list in dataset S5). Figure S6. Expression of marker genes/categories used to evaluate the co-purification of additional tissues. Figure S7. AlaAT and 40S ribosome distributions

    S4, By gene 3' bias.

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    The 3' bias of RNAseq read coverage for every gene in every study calculated with PicardTools' RnaSeqMetrics, which is defined as " mean coverage of the 3' most 100 bases divided by the mean coverage of the whole transcript" (http://broadinstitute.github.io/picard/picard-metric-definitions.html#RnaSeqMetrics). Missing (NA) values occur when (whole transcript) coverage drops too low
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