Idiopathic Pulmonary Fibrosis

This paper provides an overview of the history of IPF as well as current diagnosis and disease progression. Several common etiologies and treatments for the condition of IPF will be covered in depth. General etiology categories include age, gender, race, smoking habits, GERD (gastroesophageal reflux diseases), viruses, and environmental factors. The current treatment strategies for IPF break into medications, therapy, and standards of care. Grasping all the different factors and management is vital for educating our patients, managing the symptoms, and improving the quality of life of our patients as they take on this challenging disease. Keywords: ild, smoking, idiopathic, treatment, environmental factors

Is Stripping Women of Reproductive Rights a Form of Femicide?

My research explores the causes and consequences of the 2022 Supreme Court decision to overturn Roe v. Wade. I examine how this ruling has increased risks to women\u27s health and safety, particularly in states with abortion bans, and highlight the urgent need for federal policies to restore reproductive rights and ensure safe healthcare access. Faculty Sponsor: Professor David Goldber

Synthesizing Diazeniumdiolates from Primary Amines as Nitroxyl Donors

The use of Nitroxyl (HNO) donors has been shown to have a multitude of pharmaceutical and medicinal uses, ranging from slowing tumor growth to treatment of alcoholism. Primary amine based diazeniumdiolates, also known as NONOates, are extensively used in biochemical, physiological and pharmacological studies due to their ability to slowly release Nitroxyl (HNO.). While their counterpart, secondary amine based diazeniumdiolates can slowly release nitric oxide (NO). Herein, we report the synthesis, characterization and chemical properties of several primary amine-based diazeniumdiolates. These compounds extend the range of known diazeniumdiolate-based HNO donors. For our study, the primary amines we used were: Isopropylamine, Cyclopentylamine and 4-methylcyclohexylamine. Faculty Sponsor: Cory DiCarl

A prehistoric presentation of osteoarthritis (degenerative joint disease) in the marine reptile Tylosaurus

The fossilized remains of Tylosaurus, a gigantic marine predator from the time of the dinosaurs, were uncovered in the Late Cretaceous of South Dakota. Gross pathology was noted on the right fore-paddle. Investigation found considerable osteophyte growth on the appendicular surfaces of the right humerus, radius, and ulna, indicative of osteoarthritis, a chronic degenerative joint disease. Faculty Sponsor: Professor Isabella Reye

Her Hair

SETTING: Inside Keira’s bedroom. A door on the left side, a twin-sized bed in the back corner, and a desk with a full-body mirror on the right side of the room. Director: Bre Auriemme Actors: Sophia Marino; Ross Dumont Snider Stage Directions: Neela Lug