11 research outputs found

    Aldose Reductase Genotypes and Cardiorenal Complications: An 8-year prospective analysis of 1,074 type 2 diabetic patients

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    OBJECTIVE—We report the independent risk association of type 2 diabetic nephropathy with the z−2 allele of the 5â€Č-(CA)n microsatellite and C-106T promoter polymorphisms of the aldose reductase gene (ALR2) using a case-control design. In this expanded cohort, we examined their predictive roles on new onset of cardiorenal complications using a prospective design

    Diabetic Kidney Disease

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