61 research outputs found

    Fatigue behavior of friction stir spot welding and riveted joints in an Al alloy

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    AbstractThe main aim of this study was to compare the fatigue resistance of welded joints produced by FSSW process and riveted joints of AA2024 alloy. The specimens welded with the best preliminary parameters determined by previous tensile shear tests were tested in fatigue under load control, R=0.1, at room temperature. Two welding parameter sets were used, and P-N curves (load versus cycles) were plotted, using 2×106 cycles as the fatigue life limit. A similar curve was obtained for riveted specimens. The FSSW welding procedures were carried out in a CNC milling machining and the riveted specimens were produced in accordance with aircraft industry parameters. Although the welded specimens presented almost the same results in the tensile shear tests, the results were fairly lower than those observed for riveted joints in fatigue. The main failure mode observed in the welded joints was shearing, besides some cases of crack propagation in the perpendicular load direction, while for riveted specimens occurred mainly fretting nucleation followed by crack propagation in the perpendicular load direction. The evidences of shearing and lower fatigue lives for welded specimens indicate that the joint geometry highly affects the joint properties, due probably to stress concentrators presented locally

    Correction to: Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders

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    The original version of this article unfortunately contained mistake in the affiliation. Affiliation 1 should be read as �Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran�. The original article has been corrected. © 2018 Springer Science+Business Media, LLC, part of Springer Natur

    Correction to: Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders

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    The original version of this article unfortunately contained mistake in the affiliation. Affiliation 1 should be read as �Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran�. The original article has been corrected. © 2018 Springer Science+Business Media, LLC, part of Springer Natur

    Correction to: Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders (Molecular Neurobiology, (2019), 56, 1, (307-318), 10.1007/s12035-018-0968-1)

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    The original version of this article unfortunately contained mistake in the affiliation. Affiliation 1 should be read as �Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran�. The original article has been corrected. © 2018, Springer Science+Business Media, LLC, part of Springer Nature

    Formation of dense partonic matter in relativistic nucleus-nucleus collisions at RHIC: Experimental evaluation by the PHENIX collaboration

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    Extensive experimental data from high-energy nucleus-nucleus collisions were recorded using the PHENIX detector at the Relativistic Heavy Ion Collider (RHIC). The comprehensive set of measurements from the first three years of RHIC operation includes charged particle multiplicities, transverse energy, yield ratios and spectra of identified hadrons in a wide range of transverse momenta (p_T), elliptic flow, two-particle correlations, non-statistical fluctuations, and suppression of particle production at high p_T. The results are examined with an emphasis on implications for the formation of a new state of dense matter. We find that the state of matter created at RHIC cannot be described in terms of ordinary color neutral hadrons.Comment: 510 authors, 127 pages text, 56 figures, 1 tables, LaTeX. Submitted to Nuclear Physics A as a regular article; v3 has minor changes in response to referee comments. Plain text data tables for the points plotted in figures for this and previous PHENIX publications are (or will be) publicly available at http://www.phenix.bnl.gov/papers.htm

    Saturation of azimuthal anisotropy in Au + Au collisions at sqrt(s_NN) = 62 - 200 GeV

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    New measurements are presented for charged hadron azimuthal correlations at mid-rapidity in Au+Au collisions at sqrt(s_NN) = 62.4 and 200 GeV. They are compared to earlier measurements obtained at sqrt(s_NN) = 130 GeV and in Pb+Pb collisions at sqrt(s_NN) = 17.2 GeV. Sizeable anisotropies are observed with centrality and transverse momentum (p_T) dependence characteristic of elliptic flow (v_2). For a broad range of centralities, the observed magnitudes and trends of the differential anisotropy, v_2(p_T), change very little over the collision energy range sqrt(s_NN) = 62-200 GeV, indicating saturation of the excitation function for v_2 at these energies. Such a saturation may be indicative of the dominance of a very soft equation of state for sqrt(s_NN) = 62-200 GeV.Comment: 432 authors, 7 pages text, 4 figures, REVTeX4. To be submitted to Physical Review Letters. Plain text data tables for the points plotted in figures for this and previous PHENIX publications are (or will be) publicly available at http://www.phenix.bnl.gov/papers.htm

    Enhanced antimicrobial and full-thickness wound healing efficiency of hydrogels loaded with heparinized ZnO nanoparticles: In vitro and in vivo evaluation

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    Nanotechnology-based fabricated wound dressings are known as appropriate substrates to enhance healing in both acute and chronic wounds. These types of materials have the ability to deliver therapeutic agents. In this study, a wound dressing including heparinized zinc oxide nanoparticles in combination with chitosan and poly(vinyl alcohol) was developed to investigate its antibacterial and regenerative properties in a rat model of full thickness skin wounds. By adding nanoparticles, the mechanical strength increased up to twice as compared to the sample without nanoparticles. In addition, heparin release profile follows the Hixson-Crowell release kinetic. Protein adsorption enhanced by adding nanoparticles in hydrogels and the prepared wound dressings were completely biocompatible. In terms of antibacterial activity, the minimum inhibitory concentration decreased by conjugation of heparin on the surface of zinc oxide nanoparticles compared to the non-functionalized nanoparticles, and, this shows the increased antibacterial synergistic effect by adding heparin to nanoparticles. Furthermore, it was found that the heparinized zinc oxide nanoparticles effectively accelerate wound closure, re-epithelialization and decrease collagen deposition compared to other groups after implantation. Hence, the prepared wound dressings have the capacity to significantly enhance healing of acute wounds. © 2020 Elsevier B.V

    Intrahippocampal Transplantation of Undifferentiated Human Chorionic- Derived Mesenchymal Stem Cells Does Not Improve Learning and Memory in the Rat Model of Sporadic Alzheimer Disease

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    BACKGROUND AND OBJECTIVE: Alzheimer's Disease (AD) is a progressive neurodegenerative disorder with consequent cognitive impairment and behavioral deficits. AD is characterized by loss of cholinergic neurons and the presence of beta-amyloid protein deposits. Stem cell transplantation seems to be a promising strategy for regeneration of defects in the brain. METHOD: One of the suitable type of stem cells originated from fetal membrane is Chorion-derived Mesenchymal Stem Cells (C-MSCs). MSCs were isolated from chorion and characterized by Flowcytometric analysis. Then C-MSCs labeled with DiI were transplanted into the STZ induced Alzheimer disease model in rat. RESULTS: Nissl staining and behavior test were used to assess the efficacy of the transplanted cells. Phenotypic and Flowcytometric studies showed that isolated cells were positive for mesenchymal stem cell marker panel with spindle like morphology. CONCLUSION: Learning and memory abilities were not improved after stem cell transplantation. C-MSCs transplantation can successfully engraft in injured site but the efficacy and function of transplanted cells were not clinically satisfied. Copyright© Bentham Science Publishers; For any queries, please email at [email protected]
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