139 research outputs found

    Abrupt sea surface pH change at the end of the Younger Dryas in the central sub-equatorial Pacific inferred from boron isotope abundance in corals (<i>Porites</i>)

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    The "δ<sup>11</sup>B-pH" technique was applied to modern and ancient corals <i>Porites</i> from the sub-equatorial Pacific areas (Tahiti and Marquesas) spanning a time interval from 0 to 20.720 calendar years to determine the amplitude of pH changes between the Last Glacial Period and the Holocene. Boron isotopes were measured by Multi-Collector – Inductively Coupled Plasma Mass Spectrometry (MC-ICPMS) with an external reproducibility of 0.25&permil;, allowing a precision of about &plusmn;0.03 pH-units for pH values between 8 and 8.3. The boron concentration [B] and isotopic composition of modern samples indicate that the temperature strongly controls the partition coefficient K<sub><i>D</i></sub> for different aragonite species. Modern coral δ<sup>11</sup>B values and the reconstructed sea surface pH values for different Pacific areas match the measured pH expressed on the seawater scale and confirm the calculation parameters that were previously determined by laboratory calibration exercises. Most ancient sea surface pH reconstructions near Marquesas are higher than modern values. These values range between 8.19 and 8.27 for the Holocene and reached 8.30 at the end of the last glacial period (20.7 kyr BP). At the end of the Younger Dryas (11.50&plusmn;0.1 kyr BP), the central sub-equatorial Pacific experienced a dramatic drop of up to 0.2 pH-units from the average pH of 8.2 before and after this short event. Using the marine carbonate algorithms, we recalculated the aqueous <i>p</i>CO<sub>2</sub> to be 440&plusmn;25 ppmV at around 11.5 kyr BP for corals at Marquesas and ~500 ppmV near Tahiti where it was assumed that <i>p</i>CO<sub>2</sub> in the atmosphere was 250 ppmV. Throughout the Holocene, the difference in <i>p</i>CO<sub>2</sub> between the ocean and the atmosphere at Marquesas (Δ<i>p</i>CO<sub>2</sub>) indicates that the surface waters behave as a moderate CO<sub>2</sub> sink or source (−53 to 20 ppmV) during El Niño-like conditions. By contrast, during the last glacial/interglacial transition, this area was a marked source of CO<sub>2</sub> (21 to 92 ppmV) for the atmosphere, highlighting predominant La Niña-like conditions. Such conditions were particularly pronounced at the end of the Younger Dryas with a large amount of CO<sub>2</sub> released with Δ<i>p</i>CO<sub>2</sub> of +185&plusmn;25 ppmV. This last finding provides further evidence of the marked changes in the surface water pH and temperature in the equatorial Pacific at the Younger Dryas-Holocene transition and the strong impact of oceanic dynamic on the atmospheric CO<sub>2</sub> content

    Submarine record of volcanic island construction and collapse in the Lesser Antilles arc: First scientific drilling of submarine volcanic island landslides by IODP Expedition 340

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    IODP Expedition 340 successfully drilled a series of sites offshore Montserrat, Martinique and Dominica in the Lesser Antilles from March to April 2012. These are among the few drill sites gathered around volcanic islands, and the first scientific drilling of large and likely tsunamigenic volcanic island-arc landslide deposits. These cores provide evidence and tests of previous hypotheses for the composition and origin of those deposits. Sites U1394, U1399, and U1400 that penetrated landslide deposits recovered exclusively seafloor-sediment, comprising mainly turbidites and hemipelagic deposits, and lacked debris avalanche deposits. This supports the concepts that i/ volcanic debris avalanches tend to stop at the slope break, and ii/ widespread and voluminous failures of pre-existing low-gradient seafloor sediment can be triggered by initial emplacement of material from the volcano. Offshore Martinique (U1399 and 1400), the landslide deposits comprised blocks of parallel strata that were tilted or micro-faulted, sometimes separated by intervals of homogenized sediment (intense shearing), while Site U1394 offshore Montserrat penetrated a flat-lying block of intact strata. The most likely mechanism for generating these large-scale seafloor-sediment failures appears to be propagation of a decollement from proximal areas loaded and incised by a volcanic debris avalanche. These results have implications for the magnitude of tsunami generation. Under some conditions, volcanic island landslide deposits comprised of mainly seafloor sediment will tend to form smaller magnitude tsunamis than equivalent volumes of subaerial block-rich mass flows rapidly entering water. Expedition 340 also successfully drilled sites to access the undisturbed record of eruption fallout layers intercalated with marine sediment which provide an outstanding high-resolution dataset to analyze eruption and landslides cycles, improve understanding of magmatic evolution as well as offshore sedimentation processes. This article is protected by copyright. All rights reserved

    May Measurement Month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension

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    Aims Raised blood pressure (BP) is the biggest contributor to mortality and disease burden worldwide and fewer than half of those with hypertension are aware of it. May Measurement Month (MMM) is a global campaign set up in 2017, to raise awareness of high BP and as a pragmatic solution to a lack of formal screening worldwide. The 2018 campaign was expanded, aiming to include more participants and countries. Methods and results Eighty-nine countries participated in MMM 2018. Volunteers (≥18 years) were recruited through opportunistic sampling at a variety of screening sites. Each participant had three BP measurements and completed a questionnaire on demographic, lifestyle, and environmental factors. Hypertension was defined as a systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg, or taking antihypertensive medication. In total, 74.9% of screenees provided three BP readings. Multiple imputation using chained equations was used to impute missing readings. 1 504 963 individuals (mean age 45.3 years; 52.4% female) were screened. After multiple imputation, 502 079 (33.4%) individuals had hypertension, of whom 59.5% were aware of their diagnosis and 55.3% were taking antihypertensive medication. Of those on medication, 60.0% were controlled and of all hypertensives, 33.2% were controlled. We detected 224 285 individuals with untreated hypertension and 111 214 individuals with inadequately treated (systolic BP ≥ 140 mmHg or diastolic BP ≥ 90 mmHg) hypertension. Conclusion May Measurement Month expanded significantly compared with 2017, including more participants in more countries. The campaign identified over 335 000 adults with untreated or inadequately treated hypertension. In the absence of systematic screening programmes, MMM was effective at raising awareness at least among these individuals at risk

    The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

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    INTRODUCTION Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic. RATIONALE We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs). RESULTS Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants. CONCLUSION Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century

    Carbone-14 et environnement global : variabilité naturelle et apports anthropiques

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    Les variations passées du carbone-14 atmosphérique peuvent être reconstruites sur les derniers 50 000 ans par l'étude des différences entre âges carbone-14 et âges calendaires. Liées en premier lieu à la modulation géomagnétique du taux de production du 14C par le rayonnement cosmique et aux variations d'origine climatique du stock de 14C océanique, ces variations ont atteint un facteur 2 au début du paléolithique supérieur. Des variations de même amplitude ont été provoquées par les essais nucléaires militaires des années 50 et 60. La contribution cumulée de l'industrie nucléaire depuis ses débuts jusqu'à nos jours est de l'ordre d'un centième des quantités relâchées dans l'environnement par les retombées des explosions nucléaires atmosphériques. Représentant annuellement 14 % du taux de production naturel de 14C, cette contribution au rapport isotopique 14C/12C est actuellement contrebalancée par l'effet de dilution du 14C par les émissions de CO2 fossile (effet Suess)

    Carbone-14 et environnement global : variabilité naturelle et apports anthropiques

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    North Atlantic sea surface conditions during the Younger Dryas cold event

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