10 research outputs found
Microbial community structure and dynamics in thermophilic composting viewed through metagenomics and metatranscriptomics
- Author
- Antunes Luciana Principal
- Barbosa Deibs
- Condomitti Epamino George Willian
- da Cruz Joao Batista
- da Silva Aline Maria
- Digiampietri Luciano Antonio
- Lemos Leandro Nascimento
- Lombardi Karen Cristina
- Machado Silva Gianluca Major
- Martins Layla Farage
- Oliveira Julio Cezar Franco de
- Pascon Renata Castiglioni
- Pereira Roberta Verciano
- Quaggio Ronaldo Bento
- Ramos Patricia Locosque
- Setubal Joao Carlos
- Silva Moura Livia Maria
- Thomas Andrew Maltez
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Composting is a promising source of new organisms and thermostable enzymes that may be helpful in environmental management and industrial processes. Here we present results of metagenomicand metatranscriptomic-based analyses of a large composting operation in the Sao Paulo Zoo Park. This composting exhibits a sustained thermophilic profile (50 degrees C to 75 degrees C), which seems to preclude fungal activity. The main novelty of our study is the combination of time-series sampling with shotgun DNA, 16S rRNA gene amplicon, and metatranscriptome high-throughput sequencing, enabling an unprecedented detailed view of microbial community structure, dynamics, and function in this ecosystem. The time-series data showed that the turning procedure has a strong impact on the compost microbiota, restoring to a certain extent the population profile seen at the beginning of the processand that lignocellulosic biomass deconstruction occurs synergistically and sequentially, with hemicellulose being degraded preferentially to cellulose and lignin. Moreover, our sequencing data allowed near-complete genome reconstruction of five bacterial species previously found in biomass-degrading environments and of a novel biodegrading bacterial species, likely a new genus in the order Bacillales. The data and analyses provided are a rich source for additional investigations of thermophilic composting microbiology.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Provost's Office for Research of the University of Sao PauloCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Univ Sao Paulo, Inst Quim, Dept Bioquim, Sao Paulo, BrazilUniv Sao Paulo, Programa Pos Graduacao Interunidades Bioinformat, Sao Paulo, BrazilUniv Sao Paulo, Escola Artes Ciencias & Humanidades, Sao Paulo, Brazil|Fundacao Parque Zool Sao Paulo, Sao Paulo, BrazilUniv Fed Sao Paulo, Dept Ciencias Biol, Sao Paulo, BrazilBiocomplex Inst Virginia, Blacksburg, VA USADepartamento de Ciências Biológicas, Universidade Federal de São Paulo, São Paulo, BrazilFAPESP: 2011/50870-6Web of Scienc
Cabbage and fermented vegetables : From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19
- Author
- Abdul Latiff Amir Hamzah
- Abdullah Baharudin
- Aberer Werner
- Abusada Nancy
- Adcock Ian
- Afani Alejandro
- Agache Ioana
- Aggelidis Xenofon
- Agustin Jenifer
- Akdis Cezmi A.
- Akdis Cezmi A.
- Akdis Mubeccel
- Al-Ahmad Mona
- Al-Zahab Bassam Abou
- Alburdan Hussam
- Aldrey-Palacios Oscar
- Alvarez Cuesta Emilio
- Alwan Salman Hiba
- Alzaabi Ashraf
- Amade Salma
- Ambrocio Gene
- Angles Rosana
- Annesi-Maesano Isabella
- Ansotegui Ignacio J.
- Anto Josep M.
- Anto Josep M.
- Ara Bardajo Paula
- Arasi Stefania
- Arrais Margarete
- Arshad Hasan
- Artesani Maria-Cristina
- Asayag Estrella
- Avolio Francesca
- Azhari Khuzama
- Bachert Claus
- Bagnasco Diego
- Baiardini Ilaria
- Bajrovic Nissera
- Bakakos Petros
- Bakeyala Mongono Sergio
- Balotro-Torres Christine
- Barba Sergio
- Barbara Cristina
- Barbosa Elsa
- Barreto Bruno
- Bartra Joan
- Basagana Xavier
- Bateman Eric D.
- Battur Lkhagvaa
- Bedbrook Anna
- Bedolla Barajas Martin
- Beghe Bianca
- Bekere Antra
- Bel Elizabeth
- Ben Kheder Ali
- Bennoor Kazi S.
- Benson Mikael
- Berghea Elena-Camelia
- Bergmann Karl-Christian
- Bernardini Roberto
- Bernstein David
- Bewick Mike
- Bialek Slawomir
- Bialoszewski Artur
- Bieber Thomas
- Billo Nils E.
- Bilo Maria-Beatrice
- Bindslev-Jensen Carsten
- Bjermer Leif
- Blain Hubert
- Blain Hubert
- Bobolea Irina
- Bochenska Marciniak Malgorzata
- Bond Christine
- Boner Attilio
- Bonini Matteo
- Bonini Sergio
- Bosnic-Anticevich Sinthia
- Bosse Isabelle
- Botskariova Sofia
- Bouchard Jacques
- Boulet Louis-Philippe
- Bourret Rodolphe
- Bousquet Jean
- Bousquet Philippe
- Braido Fulvio
- Briggs Andrew
- Brightling Christopher E.
- Brozek Jan
- Brussino Luisa
- Buhl Roland
- Bumbacea Roxana
- Buquicchio Rosalva
- Burguete Cabanas Maria-Teresa
- Bush Andrew
- Busse William W.
- Buters Jeroen
- Caballero-Fonseca Fernan
- Calderon Moises A.
- Calvo Mario
- Camargos Paulo
- Camuzat Thierry
- Canevari F. R.
- Cano Antonio
- Canonica G. Walter
- Capriles-Hulett Arnaldo
- Caraballo Luis
- Cardona Vicky
- Carlsen Kai-Hakon
- Carmona Pirez Jonas
- Caro Jorge
- Carr Warner
- Carreiro-Martins Pedro
- Carreon-Asuncion Fredelita
- Carriazo Ana-Maria
- Carrion y Ribas Carme
- Casale Thomas
- Castor Mary-Ann
- Castro Elizabeth
- Caviglia A. G.
- Cecchi Lorenzo
- Cepeda Sarabia Alfonso
- Chalubinski Maciej
- Chandrasekharan Ramanathan
- Chang Yoon-Seok
- Chato-Andeza Victoria
- Chatzi Lida
- Chatzidaki Christina
- Chavannes Niels H.
- Chaves Loureiro Claudia
- Chavez Garcia Aurora-Alejandra
- Chelninska Marta
- Chen Yuzhi
- Cheng Lei
- Chinthrajah Sharon
- Chivato Tomas
- Chkhartishvili Ekaterine
- Christoff George
- Chrystyn Henry
- Chu Derek K.
- Chua Antonio
- Chuchalin Alexander
- Chung Kian Fan
- Ciceran Alberto
- Cingi Cemal
- Ciprandi Giorgio
- Cirule Ieva
- Coelho Ana-Carla
- Compalati Enrico
- Constantinidis Jannis
- Correia de Sousa Jaime
- Costa David
- Costa Elisio Manuel
- Coste Andre
- Cottini M.
- Cox Linda
- Crisci Carlos
- Crivellaro Maria Angiola
- Cruz Alvaro A.
- Cullen John
- Custovic Adnan
- Cvetkovski Biljana
- Czarlewski Wienczyslawa
- Czarlewski Wienczyslawa
- D'Amato Gennaro
- da Silva Jane
- Dahl Ronald
- Dahlen Sven-Erik
- Daniilidis Vasilis
- Darjazini Nahhas Louei
- Darsow Ulf
- Davies Janet
- de Blay Frederic
- De Feo Giulia
- De Guia Eloisa
- de la Luz Hortensia Garcia Cruz Maria
- de la Torre Navarrete Jose-Ricardo
- de los Santos Chato
- De Manuel Keenoy Esteban
- De Vries Govert
- De Wang Yun
- del Carmen Costa Dominguez Maria
- Deleanu Diana
- Demoly Pascal
- Denburg Judah
- Devillier Philippe
- Didier Alain
- Dimic Janjic Sanja
- Dimou Maria
- Dinh-Xuan Anh Tuan
- Djukanovic Ratko
- Do Ceu Texeira Maria
- Dokic Dejan
- Dominguez Silva Margarita Gabriela
- Douagui Habib
- Douladiris Nikolaos
- Doulaptsi Maria
- Dray Gerard
- Dubakiene Ruta
- Dupas Eve
- Durham Stephen
- Duse Marzia
- Dykewicz Mark
- Ebo Didier
- Edelbaher Natalija
- Eiwegger Thomas
- Eklund Patrik
- El-Gamal Yehia
- El-Sayed Shereen S.
- El-Sayed Zeinab A.
- El-Seify Magda
- Emuzyte Regina
- Enecilla Lourdes
- Erhola Marina
- Espinoza Contreras Jesus Guillermo
- Espinoza Heidilita
- Farrell John
- Fernandez Lenora
- Fimbres Jimenez Paola
- Fink Wagner Antje
- Fiocchi Alessandro
- Fokkens Wytske J.
- Folletti Lenia
- Fonseca Joao A.
- Fonseca Susana C.
- Fontaine Jean-Francois
- Forastiere Francesco
- Fuentes Perez Jose Miguel
- Gaerlan-Resureccion Emily
- Gaga Mina
- Galvez Romero Jose Luis
- Gamkrelidze Amiran
- Garcia Cobas Cecilia Yvonne
- Garcia Alexis
- Gayraud Jacques
- Gelardi Matteo
- Gemicioglu Bilun
- Gennimata Dimitra
- Genova Sonya
- Gereda Jose
- Gerth van Wijk Roy
- Giuliano Antonio
- Gomez Rene-Maximiliano
- Gonzalez Ballester Miguel-Ange
- Gonzalez Diaz Sandra
- Gotua Maia
- Grigoreas Christos
- Grisle Ineta
- Guidacci Marta
- Guldemond Nick
- Gutter Zdenek
- Guzman Antonieta
- Haahtela Tari
- Haahtela Tari
- Halloum Ramsa
- Halpin David
- Hamelmann Eckard
- Hammadi Suleiman
- Harvey Richard
- Heffler Enrico
- Heinrich Joachim
- Hejjaoui Adnan
- Hellquist-Dahl Birthe
- Hernandez Velazquez Luiana
- Hew Mark
- Hossny Elham
- Howarth Peter
- Hrubisko Martin
- Huerta Villalobos Yunuen Rocio
- Humbert Marc
- Husain Salina
- Hyland Michael
- Iaccarino Guido
- Iaccarino Guido
- Ibrahim Moustafa
- Ilina Nataliya
- Illario Maddalena
- Incorvaia Cristoforo
- Infantino Antonio
- Irani Carla
- Ispayeva Zhanat
- Ivancevich Juan Carlos
- Jares Edgardo E. J.
- Jarvis Deborah
- Jassem Ewa
- Jenko Klemen
- Jimeneracruz Uscanga Ruben Dario
- Johnston Sebastian L.
- Joos Guy
- Jost Maja
- Julge Kaja
- Jung Ki-Suck
- Just Jocelyne
- Jutel Marek
- Kaidashev Igor
- Kalayci Omer
- Kalyoncu Fuat
- Kapsali Jeni
- Kardas Przemyslaw
- Karjalainen Jussi
- Kasala Carmela A.
- Katotomichelakis Michael
- Kavaliukaite Loreta
- Keil Thomas
- Keith Paul
- Khaitov Musa
- Khaltaev Nikolai
- Kim You-Young
- Kirenga Bruce
- Kleine-Tebbe Jorg
- Klimek Ludger
- Ko Fanny W.
- Koffi N'Goran Bernard
- Kompoti Evangelia
- Kopac Peter
- Koppelman Gerard
- Koren Jeverica Anja
- Koskinen Seppo
- Kosnik Mitja
- Kostka Tomasz
- Kostov Kosta V.
- Kowalski Marek L.
- Kralimarkova Tanya
- Kramer Vrscaj Karmen
- Kraxner Helga
- Kreft Samo
- Kritikos Vicky
- Kudlay Dmitry
- Kuitunen Mikael
- Kull Inger
- Kuna Piotr
- Kupczyk Maciej
- Kvedariene Violeta
- Kyriakakou Marialena
- Lalek Nika
- Landi Massimo
- Lane Stephen
- Larenas-Linnemann Desiree E.
- Lau Susanne
- Laune Daniel
- Lavrut Jorge
- Le Lan
- Lenzenhuber Martina
- Leo Gualtiero
- Lessa Marcus
- Levin Michael
- Li Jing
- Lieberman Philip
- Liotta Giuseppe
- Lipworth Brian
- Liu Xuandao
- Lobo Rommel
- Lodrup Carlsen Karin C.
- Lombardi Carlo
- Louis Renaud
- Loukidis Stelios
- Lourenco Olga
- Luna Pech Jorge A.
- Madjar Bojan
- Maggi Enrico
- Magnan Antoine
- Mahboub Bassam
- Mair Alpana
- Maitland van der Zee Anke-Hilse
- Makela Mika
- Makris Michael
- Malling Hans-Jorgen
- Mandajieva Mariana
- Manning Patrick
- Manousakis Manolis
- Maragoudakis Pavlos
- Marseglia Gianluigi
- Marshall Gailen
- Masjedi Mohammad Reza
- Maspero Jorge F.
- Matta Campos Juan Jose
- Maurer Marcus
- Mavale-Manuel Sandra
- Meco Cem
- Melen Erik
- Melioli Giovanni
- Melo-Gomes Elisabete
- Meltzer Eli O.
- Menditto Enrica
- Menzies-Gow Andrew
- Merk Hans
- Michel Jean-Pierre
- Micheli Yann
- Miculinic Neven
- Midao Luis
- Mihaltan Florin
- Mikos Nikolaos
- Milanese Manlio
- Milenkovic Branislava
- Mitsias Dimitrios
- Moalla Bassem
- Moda Giuliana
- Mogica Martinez Maria Dolores
- Mohammad Yousser
- Moharra Frances-Montserrat
- Moin Mostafa
- Molimard Mathieu
- Momas Isabelle
- Mommers Monique
- Monaco Alessandro
- Montefort Stephen
- Montenegro Lucia-Elvira
- Monti Riccardo
- Mora Dory
- Morais-Almeida Mario
- Mosges Ralph
- Mostafa Badr Eldin
- Mullol Joaquim
- Munter Lars
- Muraro Antonella
- Murray Ruth
- Musarra Antonio
- Mustakov Tihomir
- Naclerio Robert
- Nadeau Kari C.
- Nadif Rachel
- Nakonechna Alla
- Namazova-Baranova Leyla
- Navarro-Locsin Gretchen
- Neffen Hugo
- Nekam Kristof
- Neou Angelos
- Nettis Eustachio
- Neuberger Daniel
- Nicod Laurent
- Nicola Stefania
- Niederberger-Leppin Verena
- Niedoszytko Marek
- Nieto Antonio
- Novellino Ettore
- Nunes Elizabete
- Nyembue Dieudonne
- O'Hehir Robyn E.
- Odjakova Cvetanka
- Ohta Ken
- Okamoto Yoshitaka
- Okubo Kimi
- Oliver Brian
- Onorato Gabrielle L.
- Orru Maria Pia
- Ortiz Valeria Garcia
- Ouedraogo Solange
- Ouoba Kampadilemba
- Padilla Francisco-Javier
- Paggiaro Pier Luigi
- Pagkalos Aris
- Pajno Giovanni
- Pala Gianni
- Palaniappan S. P.
- Pali-Scholl Isabella
- Palkonen Susanna
- Palmer Stephen
- Panaitescu Bunu Carmen
- Panzner Petr
- Papadopoulos Nikos G.
- Papanikolaou Vasilis
- Papi Alberto
- Paralchev Bojidar
- Paraskevopoulos Giannis
- Park Hae-Sim
- Passalacqua Giovanni
- Patella Vincenzo
- Pavord Ian
- Pawankar Ruby
- Pedersen Soren
- Peleve Susete
- Pellegino Simona
- Pereira Ana
- Pereira Mariana
- Perez Tamara
- Perna Andrea
- Peroni Diego
- Pfaar Oliver
- Pham-Thi Nhan
- Pigearias Bernard
- Pin Isabelle
- Pinto Barnaro Sousa
- Piskou Konstantina
- Pitsios Constantinos
- Plavec Davor
- Poethig Dagmar
- Pohl Wolfgang
- Poplas Susic Antonija
- Popov Todor A.
- Portejoie Fabienne
- Potter Paul
- Poulsen Lars
- Prados-Torres Alexandra
- Prarros Fotis
- Price David
- Prokopakis Emmanuel
- Puggioni Francesca
- Puig-Domenech Elisa
- Puy Robert
- Rabe Klaus
- Rabotti Silvia
- Raciborski Filip
- Ramos Josephine
- Recalcati Cristina
- Recto Marysia T.
- Reda Shereen M.
- Regateiro Frederico S.
- Reider Norbert
- Reitsma Sietze
- Repka-Ramirez Susana
- Ridolo Erminia
- Rimmer Janet
- Rivero Yeverino Daniela
- Rizzo Jose Angelo
- Robalo-Cordeiro Carlos
- Roberts Graham
- Robles Karen
- Roche Nicolas
- Rodriguez Gonzalez Monica
- Rodriguez Zagal Erendira
- Rolla Giovanni
- Rolland Christine
- Roller-Wirnsberger Regina
- Roman Rodriguez Miguel
- Romano Antonino
- Romantowski Jan
- Rombaux Philippe
- Romualdez Joel
- Rosado-Pinto Jose
- Rosario Nelson
- Rosenwasser Lanny
- Rossi Oliviero
- Rottem Menachem
- Rouadi Philip W.
- Rovina Nikoleta
- Rozman Sinur Irma
- Ruiz Segura Lucy Tania
- Ruiz Mauricio
- Ryan Dermot
- Sagara Hironori
- Sakai Daiki
- Sakurai Daiju
- Saleh Wafaa
- Salimaki Johanna
- Samitas Konstantinos
- Samolinski Boleslaw
- Sanchez Coronel Maria Guadalupe
- Sanchez-Borges Mario
- Sanchez-Lopez Jaime
- Sansonna Melissa
- Sarafoleanu Codrut
- Sarquis Serpa Faradiba
- Sastre Joaquin
- Savi Eleonora
- Savonyte Agne
- Sawaf Bisher
- Scadding Glenis K.
- Scheire Sophie
- Schmid-Grendelmeier Peter
- Schuhl Juan Francisco
- Schunemann Holger
- Schvalbova Maria
- Schwarze Jorgen
- Scichilone Nicola
- Senna Gianenrico
- Sepulveda Cecilia
- Serrano Elie
- Shamai Sara
- Sheikh Aziz
- Sheikh Aziz
- Shields Mike
- Shishkov Vasil
- Siafakas Nikos
- Simeonov Alexander
- Simons Estelle F. E. R.
- Sisul Juan Carlos
- Sitkauskiene Brigita
- Skrindo Ingelbjorg
- Soklic Kosak Tanja
- Sole Dirceu
- Sondermann Martin
- Sooronbaev Talant
- Soto-Martinez Manuel
- Soto-Quiros Manuel
- Sova Milan
- Soyka Michael
- Specjalski Krzysztof
- Sperl Annette
- Spranger Otto
- Stamataki Sofia
- Stefanaki Lina
- Stellato Cristiana
- Stelmach Rafael
- Strandberg Timo
- Stute Petra
- Subramaniam Abirami
- Suppli Ulrik Charlotte
- Sutherland Michael
- Sylvestre Silvia
- Syrigou Aikaterini
- Taborda Barata Luis
- Takovska Nadejda
- Tan Frances
- Tan Rachel
- Tan Vincent
- Tang Ing Ping
- Taniguchi Masami
- Tannert Line
- Tantilipikorn Pongsakorn
- Tattersall Jessica
- Tesi Filippo
- Thieme Uta
- Thijs Carel
- Thomas Mike
- To Teresa
- Todo-Bom Ana Maria
- Togias Alkis
- Tomazic Peter-Valentin
- Tomic-Spiric Vesna
- Toppila-Salmi Sanna
- Torres Jaen Maria-Jose
- Toskala Elina
- Tran Thien Quan Vu
- Triggiani Massimo
- Triller Katja
- Triller Nadja
- Tsiligianni Ioanna
- Uberti M.
- Ulmeanu Ruxandra
- Urbancic Jure
- Urrutia Pereira Marilyn
- Vachova Martina
- Valdes Felipe
- Valenta Rudolf
- Valentin Rostan Marylin
- Valero Antonio
- Valiulis Arunas
- Vallianatou Mina
- Valovirta Erkka
- Van Eerd Michiel
- Van Ganse Eric
- van Hage Marianne
- Vandenplas Olivier
- Vasankari Tuula
- Vassileva Dafina
- Velasco Munoz Cesar
- Ventura Maria Teresa
- Vera-Munoz Cecilia
- Viart Frederic
- Vicheva Dilyana
- Vichyanond Pakit
- Vidal Alain
- Vidgren Petra
- Viegi Giovanni
- Vogelmeier Claus
- Von Hertzen Leena
- Vontetsianos Theodoros
- Vourdas Dimitris
- Wagenmann Martin
- Walker Samantha
- Wallace Dana
- Waserman Susan
- Wehner Katrin
- Wickman Magnus
- Williams Dennis
- Williams Sian
- Wilson Nicola
- Wong Gary
- Woo Kent
- Wozniak Lucyna
- Wright John
- Wroczynski Piotr
- Xepapadaki Paraskevi
- Yakovliev Plamen
- Yamaguchi Masao
- Yan Kwok
- Yap Yoke Yeow
- Yassin Mais
- Yawn Barbara
- Yiallouros Panayiotis
- Yorgancioglu Arzu
- Yoshihara Shigemi
- Young Ian
- Yusuf Osman B.
- Zaidi Asghar
- Zaitoun Fares
- Zalud Petra
- Zar Heather
- Zedda M. T.
- Zernotti Mario E.
- Zhang Luo
- Zhong Nanshan
- Zidarn Mihaela
- Zuberbier Torsten
- Zuberbier Torsten
- Zubrinich Celia
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT(1)R) axis associated with oxidative stress. This leads to insulin resistance as well as lung and endothelial damage, two severe outcomes of COVID-19. The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the most potent antioxidant in humans and can block in particular the AT(1)R axis. Cabbage contains precursors of sulforaphane, the most active natural activator of Nrf2. Fermented vegetables contain many lactobacilli, which are also potent Nrf2 activators. Three examples are: kimchi in Korea, westernized foods, and the slum paradox. It is proposed that fermented cabbage is a proof-of-concept of dietary manipulations that may enhance Nrf2-associated antioxidant effects, helpful in mitigating COVID-19 severity.Peer reviewe
Nrf2-interacting nutrients and COVID-19 : time for research to develop adaptation strategies
- Author
- Abdul Latiff Amir Hamzah
- Abdullah Baharudin
- Aberer Werner
- Abusada Nancy
- Adcock Ian
- Afani Alejandro
- Agache Ioana
- Aggelidis Xenofon
- Agustin Jenifer
- Akdis Cezmi A.
- Akdis Cezmi A.
- Akdis Mubeccel
- Al-Ahmad Mona
- Al-Zahab Bassam Abou
- Alburdan Hussam
- Aldrey-Palacios Oscar
- Alvarez Cuesta Emilio
- Alwan Salman Hiba
- Alzaabi Ashraf
- Amade Salma
- Ambrocio Gene
- Angles Rosana
- Annesi-Maesano Isabella
- Ansotegui Ignacio J.
- Anto Josep M.
- Anto Josep M.
- Ara Bardajo Paula
- Arasi Stefania
- Arrais Margarete
- Arshad Hasan
- Artesani Maria-Cristina
- Asayag Estrella
- Avolio Francesca
- Azhari Khuzama
- Bachert Claus
- Bagnasco Diego
- Baiardini Ilaria
- Bajrovic Nissera
- Bakakos Petros
- Bakeyala Mongono Sergio
- Balotro-Torres Christine
- Barba Sergio
- Barbara Cristina
- Barbosa Elsa
- Barreto Bruno
- Bartra Joan
- Basagana Xavier
- Bateman Eric D.
- Battur Lkhagvaa
- Bedbrook Anna
- Bedolla Barajas Martin
- Beghe Bianca
- Bekere Antra
- Bel Elizabeth
- Ben Kheder Ali
- Bennoor Kazi S.
- Benson Mikael
- Berghea Elena-Camelia
- Bergmann Karl-Christian
- Bernardini Roberto
- Bernstein David
- Bewick Mike
- Bialek Slawomir
- Bialoszewski Artur
- Bieber Thomas
- Billo Nils E.
- Bilo Maria-Beatrice
- Bindslev-Jensen Carsten
- Bjermer Leif
- Blain Hubert
- Blain Hubert
- Bobolea Irina
- Bochenska Marciniak Malgorzata
- Bond Christine
- Boner Attilio
- Bonini Matteo
- Bonini Sergio
- Bosnic-Anticevich Sinthia
- Bosse Isabelle
- Botskariova Sofia
- Bouchard Jacques
- Boulet Louis-Philippe
- Bourret Rodolphe
- Bousquet Jean
- Bousquet Philippe
- Braido Fulvio
- Briggs Andrew
- Brightling Christopher E.
- Brozek Jan
- Brussino Luisa
- Buhl Roland
- Bumbacea Roxana
- Buquicchio Rosalva
- Burguete Cabanas Maria-Teresa
- Bush Andrew
- Busse William W.
- Buters Jeroen
- Caballero-Fonseca Fernan
- Calderon Moises A.
- Calvo Mario
- Camargos Paulo
- Camuzat Thierry
- Canevari F. R.
- Cano Antonio
- Canonica G. Walter
- Canonica G. Walter
- Capriles-Hulett Arnaldo
- Caraballo Luis
- Cardona Vicky
- Carlsen Kai-Hakon
- Carmona Pirez Jonas
- Caro Jorge
- Carr Warner
- Carreiro-Martins Pedro
- Carreon-Asuncion Fredelita
- Carriazo Ana-Maria
- Carrion y Ribas Carme
- Casale Thomas
- Castor Mary-Ann
- Castro Elizabeth
- Caviglia A. G.
- Cecchi Lorenzo
- Cepeda Sarabia Alfonso
- Chalubinski Maciej
- Chandrasekharan Ramanathan
- Chang Yoon-Seok
- Chato-Andeza Victoria
- Chatzi Lida
- Chatzidaki Christina
- Chavannes Niels H.
- Chaves Loureiro Claudia
- Chavez Garcia Aurora-Alejandra
- Chelninska Marta
- Chen Yuzhi
- Cheng Lei
- Chinthrajah Sharon
- Chivato Tomas
- Chkhartishvili Ekaterine
- Choi Hak-Jong
- Christoff George
- Chrystyn Henry
- Chu Derek K.
- Chua Antonio
- Chuchalin Alexander
- Chung Kian Fan
- Ciceran Alberto
- Cingi Cemal
- Ciprandi Giorgio
- Cirule Ieva
- Coelho Ana-Carla
- Compalati Enrico
- Constantinidis Jannis
- Correia de Sousa Jaime
- Costa David
- Costa Elisio Manuel
- Coste Andre
- Cottini M.
- Cox Linda
- Crisci Carlos
- Cristol Jean-Paul
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- El-Sayed Zeinab A.
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- Fonseca Joao A.
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- Torres Jaen Maria-Jose
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- Viart Frederic
- Vicheva Dilyana
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- Vidgren Petra
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- Vontetsianos Theodoros
- Vourdas Dimitris
- Wagenmann Martin
- Walker Samantha
- Wallace Dana
- Waserman Susan
- Wehner Katrin
- Wickman Magnus
- Williams Dennis
- Williams Sian
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- Wong Gary
- Woo Kent
- Wozniak Lucyna
- Wright John
- Wroczynski Piotr
- Xepapadaki Paraskevi
- Yakovliev Plamen
- Yamaguchi Masao
- Yan Kwok
- Yap Yoke Yeow
- Yassin Mais
- Yawn Barbara
- Yiallouros Panayiotis
- Yorgancioglu Arzu
- Yoshihara Shigemi
- Young Ian
- Yusuf Osman B.
- Zaidi Asghar
- Zaitoun Fares
- Zalud Petra
- Zar Heather
- Zedda M. T.
- Zernotti Mario E.
- Zhang Luo
- Zhong Nanshan
- Zidarn Mihaela
- Zuberbier Torsten
- Zuberbier Torsten
- Zubrinich Celia
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
There are large between- and within-country variations in COVID-19 death rates. Some very low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a common feature of eating large quantities of fermented foods whose intake is associated with the activation of the Nrf2 (Nuclear factor (erythroid-derived 2)-like 2) anti-oxidant transcription factor. There are many Nrf2-interacting nutrients (berberine, curcumin, epigallocatechin gallate, genistein, quercetin, resveratrol, sulforaphane) that all act similarly to reduce insulin resistance, endothelial damage, lung injury and cytokine storm. They also act on the same mechanisms (mTOR: Mammalian target of rapamycin, PPAR gamma:Peroxisome proliferator-activated receptor, NF kappa B: Nuclear factor kappa B, ERK: Extracellular signal-regulated kinases and eIF2 alpha:Elongation initiation factor 2 alpha). They may as a result be important in mitigating the severity of COVID-19, acting through the endoplasmic reticulum stress or ACE-Angiotensin-II-AT(1)R axis (AT(1)R) pathway. Many Nrf2-interacting nutrients are also interacting with TRPA1 and/or TRPV1. Interestingly, geographical areas with very low COVID-19 mortality are those with the lowest prevalence of obesity (Sub-Saharan Africa and Asia). It is tempting to propose that Nrf2-interacting foods and nutrients can re-balance insulin resistance and have a significant effect on COVID-19 severity. It is therefore possible that the intake of these foods may restore an optimal natural balance for the Nrf2 pathway and may be of interest in the mitigation of COVID-19 severity
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
- Author
- Abad-Motos Ane
- Abbas Ahmed M.
- Abbas Mostafa
- Abbasi Mujeeb
- Abbott Tom
- Abd Karim Muhammad Fairuz Shah
- Abdalaal Ibrahim
- Abdel-Galil Khalid
- Abdelemam Rania
- Abdelgawad Abdalrahman
- Abdelkarim Maryam
- Abdelkhalek Mohamed
- Abdelmageed Abdelfatah
- Abdelmawgoud Sherif
- Abdelmohsen Sarah
- Abdelrahman Ahmed Saber
- Abdelrahman Mostafa
- Abdelwahab Khaled
- Abdou Hossam
- Abdulai Darling Ramatu
- Abdulkhaleq Marwa
- Abdullah Bahiyah
- Abdulsalam Khalifa
- Abdulsalam Shuaib
- Abdur-Rahman Lukman
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abebrese John Tabiri
- Abeldaño Ariel
- Abou-Khalil Jad
- Abou-Taleb Hisham
- Abozid Anwaar
- Abozied Hesham
- Abrate Alberto
- Abu-Zaid Ahmed
- Abubakar Mohammed Kabir
- Abud Burçin
- Abuzaid Mohammed
- Adam Albushra Altayeb
- Adamina Michel
- Adamou Harissou
- Adamu Auwal
- Adamu Kabir Musa
- Adanu Kekeli
- Adebara Idowu
- Adebola Oluwaseyi
- Ademuyiwa Adesoji
- Adeniran Abiodun
- Adepiti Akinfolarin
- Aderogba Adeleke Akeem
- Adesunkanmi Abdulhafiz
- Adeyeye Ademola
- Adisa Adewale
- Adjeso Theophilus Justus Kofi
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adu-Aryee Nii Armah
- Adumah Collins
- Afzal Irrum
- Agapov Mikhail
- Agarwal Gaurav
- Agarwal Ravi
- Agbeko Anita Eseenam
- Agbeno Evans Kofi
- Agbonrofo Peter
- Agboola Oluseyi
- Aggarwal Gaurav
- Aghadi Ifeanyi
- Aghtarafi Natasha
- Agrawal Amit
- Agresta Ferdinando
- Aguado Héctor J.
- Aguilera-Arevalo Maria-Lorena
- Aherne Thomas
- Ahmad Aline
- Ahmad Maleeha
- Ahmad Misbahu
- Ahmad Sarwat
- Ahmad Shahzaib
- Ahmad Shoaib
- Ahmed Hayat Tarig Abdelhafiz
- Ahmed Khalid
- Ahmed Sharwany
- Ahmed Shima
- Ahmed Usama
- Aisuodionoe-Shadrach Oseremen
- Aitken Sarah
- Ajenifuja Kayode
- Ajiya Abdulrazak
- Akeel Nouf
- Akin Emrah
- Akinajo Opeyemi
- Akinyemi Tosin
- Akrida Ioanna
- Aktokmakyan Talar Vartanoglu
- Akwaisah Ayoub
- Al Bettar Osama
- Al-Badawi Ismail A.
- Al-Juaifari Maytham
- Al-Khyatt Waleed
- Al-Mallah Abdullah
- Al-Nusairi Ahmed
- Al-Saadi Nina
- Al-Sayaghi Khaled
- Al-Shaiji Tariq
- Al-Shehari Mohammed
- Al-Touny Aiman
- Al-Touny Shimaa A.
- Aladawi Omar
- Aladna Abdallah
- Alali Mahmoud
- Alam Mahmood
- Alam Mohammed Shadrul
- Alarabi Rehab
- Alawneh Yazan
- Alayande Barnabas
- Albanese Erminia
- Albayadi Eslam
- Albdour Maram
- Alconchel Felipe
- Alderazi Amer
- Alegbeleye Bamidele
- Alekberli Tural
- Alemu Misganaw Alemu Adimass
- Alexander Philip
- Alfieri Alex
- Algahtany Khaled
- Algarni Kamal
- Alhamad Ameen
- Alhamid Mohammad
- Alharmi Rawan A. Rahman
- Alharthi Mohammed
- Alhazmi Barrag
- Ali Mohamed Shafi Mahboob
- Ali Stephen
- Alibrahim Hidar
- Aljaaly Hattan
- Aljaiuossi Anas
- Aljanadi Firas
- Aljiffry Murad
- Aljirdabi Noof
- Alkahlan Mohammed
- Alkhalifa Elmustafa
- Alkhatib Sondos
- Alkhatieb Maram
- Allan Anna
- Almarshad Felwa
- Almgla Naser
- Almhimid Ali
- Almiqlash Bushray
- Almoshantaf Mohammad Badr
- Almutairi Abdulmjeed
- Alnsour Abed Alfattah Mahmoud
- Alobied Majd
- Alomar Osama
- Alonso Jesús Aarón Martínez
- Alonso Manuel Diez
- Alonso Nestor Fabian Pedraza
- Alonso Veronica
- Alqallaf Abdullah
- Alqaseer Asma
- Alrayes Bourhan
- Alsefri Maryam
- Alser Osaid
- Alsharif Mohammed
- Alsori Mohamed
- Altaf Abdulmalik
- Altinel Yuksel
- Altiner Saygin
- Altouny Ahmad
- Altun Demet
- Alvarez Natalia
- Alvarez-Lozada Luis Adrian
- Alvi Abdul
- Alwael Athari
- Alwash Mohammed
- Alyami Ziyad
- Alyousef Mohammed
- Alzahrani Saud
- Alzerwi Nasser
- Amin Shivang
- Amir Mohammed
- Ammar Ahmed Siddique
- Ammendola Michele
- Amores Remedios Revilla
- Amrayev Sultan
- Anastasiadou Sofia
- Ancans Guntis
- Anderson Caroline
- Andreani Lorenzo
- Andreotti Dario
- Andreuccetti Jacopo
- Andrianakis Alexandros
- Andro Christophe
- Anesi Alexandre
- Angamuthu Stephen
- Angeles Martina Aida
- Angelico Roberta
- Angelis Fragkiskos
- Angelou Dimitrios
- Angelou Kyveli
- Angulo Victor Pinto
- Anjum Arfa
- Anjum Muhammad Ayyub
- Annicchiarico Alfredo
- Anoldo Pietro
- Ansaloni Luca
- Anthoulakis Christos
- Antonelli Amedeo
- Anwar Mohamed
- Anwar Sumadi Lukman
- Anwer Mariyah
- Anyanwu Lofty-John
- Apostolou Christos
- Apostolou Konstantinos
- Appiah-Kubi Adu
- Aprea Giovanni
- Arbab Hana
- Archer James
- Ardura Francisco
- Aremu Muyiwa
- Arif Tahera
- Arkani Samara
- Armatura Giulia
- Armijos Daniel
- Arnaout Ali
- Arnaoutoglou Eleni
- Arnaud Alexis P.
- Arneja Jugpal
- Arrangoiz Rodrigo
- Arshad Muhammad
- Arthur Joshua
- Ashcroft James
- Ashford Bruce
- Ashraf Fariha
- Asiimwe Daniel
- Asirifi Samuel Amoako
- Asla Amir
- Aslam Ramisha
- Aspide Raffaele
- Ataya Karim
- Ateca Ibabe Villalabeitia
- Atici Semra Demirli
- Atis Gokhan
- Atkins William
- Atkinson Kate
- Attwood Joseph
- Auerkari Aino
- Augestad Knut Magne
- Augustin Goran
- Aujayeb Avinash
- Avella Pasquale
- Awad Ahmed K.
- Awad Hadeel
- Awad Rabih
- Awad Selmy
- Ayad Kusay
- Ayana Birhanu
- Aydin Yener
- Ayeni Funbi
- Aytac Erman
- Azab Ahmed
- Azami Rizwan
- Azize Diallo Abdoul
- Azzam Ahmed Y.
- Azzis Olivier
- Baba Yabasin Iddrisu
- Babis George
- Bacalbasa Nicolae
- Badiani Sarit
- Badran Saif
- Baduell Albert
- Baeesa Saleh
- Baertschiger Reto
- Bafaquh Mohammed
- Bahassan Omar Mohammed
- Bahrami-Hessari Michael
- Baia Marco
- Baidoo Ebikela Ivie
- Bailey Karen
- Baili Efstratia
- Bains Lovenish
- Baiocchi Gian Luca
- Baiocchi Glauco
- Baiyewu Lateef Ayodele
- Bajaj Ankur
- Bajunaid Khalid
- Balagobi Balasingam
- Balasubramanian Ishwarya
- Balduzzi Alberto
- Baldwin Alexander
- Balla Andrea
- Balogh Zsolt J.
- Balogun James A.
- Balogun Simon
- Baloyiannis Ioannis
- Ban Vin Shen
- Bandyopadhyay Samik Kumar
- Bandyopadhyay Soham
- Banerjee Sumit
- Banipal Gurpreet Singh
- Banky Balazs
- Bannone Elisa
- Bansal Sujesh
- Barberis Andrea
- Barbosa-Breda Joao
- Bareka Metaxia
- Barišić Tatjana
- Barlas Aziz Mutlu
- Barlow Ciaran
- Barmayehvar Behrad
- Baroffio Paolo
- Barone Mirko
- Barra Fabio
- Barranquero Alberto G.
- Barugola Giuliano
- Basendowah Mohammed
- Bashir Mahmod
- Basnayake Oshan
- Bass Gary Alan
- Basu Somprakas
- Bateman Antony
- Bateman Kellie
- Batista Sylvia
- Batstone Martin
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- Bauset Juan Carlos Catalá
- Bawa Ashvind
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- Bazzi Nagham
- Beamish Andrew
- Beasley Nigel
- Beatty Jasmine Winter
- Becerra Angel
- Bedada Alemayehu Ginbo
- Bedzhanyan Arkady
- Begum Farzana
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- Belzile Etienne
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- Bence Matthew
- Benshetrit Guy
- Bensoltane Khadidja
- Bergkvist David Julià
- Beristain-Hernandez Jose-Luis
- Bernante Paolo
- Bernardi Daniele
- Beron Reinaldo Isaacs
- Berselli Bruno
- Berselli Mattia
- Bertelli Giacomo
- Bertoglio Pietro
- Bertolaccini Luca
- Beswick Daniel
- Bette Birgit
- Bezirci Rifat
- Bhangu Aneel
- Bharathan Rasiah
- Bhat Vivek
- Bhatti Khalid
- Bianchi Valentina
- Bianco Francesco
- Bianco Giuseppe
- Bijou Walid
- Bilfaqirah Majed
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- Maestri Marco
- Maffioli Anna
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- Venkatappa Sunil Kumar
- Venketeswaran Meenakshi
- Venskutonis Donatas
- Verbic Milena Senica
- Verdi Daunia
- Vergara-Fernandez Omar
- Verhoeff Kevin
- Veroux Massimiliano
- Verras Georgios-Ioannis
- Verre Luigi
- Vida Lucian
- Vidya Raghavan
- Viglietta Edoardo
- Vijay Vardhini
- Vijgen Guy
- Vilaró Blanca Capdevila
- Villanueva Julio
- Vilz Tim O.
- Vincent Elizabeth
- Vinci Danilo
- Viola Simona
- Violante Tommaso
- Vishnoi Jeewan Ram
- Vissapragada Ravi
- Vivancos Laura Guillamon
- Vives Josep Maria Muñoz
- Vizzielli Giuseppe
- Vohra Lubna
- Vokshi Ismail
- Vosinakis Christos
- Vásquez Javier Alberto Gutiérrez
- Vázquez Gil
- Vázquez Irene Ortega
- Vǎcǎraşu Andrei Bogdan
- Wade Ryckie
- Wafi Omar
- Wagner Gabriela
- Wallis Christopher
- Wanjara Samuel
- Waqar Shahzad Hussain
- Warden Claire
- Warner Christian
- Wasim D.
- Wason Shaun
- Wasserman Isaac
- Watcyn-Jones Tom
- Waterson Ben
- Watson David
- Watson Matthew
- Weber Clemens
- Wheatstone P.
- Wheeler James
- Wheldon Luke
- White Michelle
- White Stuart
- White William
- Wickramasinghe Dakshitha
- Widmer Lukas Werner
- Wiedemann Dominik
- Wiesinger Clemens Georg
- Wijekoon Naveen
- Wijenayake Wasantha
- Wijeyaratne Manuk
- Wijeysundera Duminda
- Wiles Matthew
- Wilkin Richard
- Wilkins Alex
- Wilkins James
- William Tinka George
- Williams Omolara Modupe
- Williams Shekinah
- Windsor John
- Winnand Philipp
- Wittmann Maria
- Wolde Amanuel
- Wolfenden John W. D.
- Wong Benjamin Ngie Xiong
- Wong Enoch
- Wong Evan G.
- Wong George Kwok Chu
- Wong Ho Ying Flora
- Wong Kai Yuen
- Wormald Justin
- Wright Deborah
- Wright Joshua
- Wu Fiona
- Wurm Markus
- Xenaki Sofia
- Yadev Ip
- Yahaya Ahmad Shuib
- Yakubu Mustapha
- Yang Wah
- Yanik Özge
- Yanowsky-Reyes Guillermo
- Yassin Abubaker
- Yates Elizabeth
- Yebes Alvaro
- Yenli Edwin Mwintiereh Ta-Ang
- Yeoh Tien
- Yeung Justin
- Yiallourou Anneza
- Yigit Banu
- Yildirim Asif
- Yim Guang
- Yiu Andrew
- Yonekura Hiroshi
- Yotsov Tsanko
- Younis Muhammad Umar
- Yunus Alif
- Yusefi Hossein
- Zabaleta Jon
- Zabkiewicz Catheriner
- Zaccaria Giulia
- Zacharia Bincy
- Zafar Syed Nabeel
- Zago Mauro
- Zaheen Zakia
- Zahid Zahra
- Zaimis Tilemachos
- Zakaria Andee Dzulkarnaen
- Zambon Martina
- Zamora Lindsey
- Zampogna Biagio
- Zancana Giuseppa
- Zani Augusto
- Zanin Luca
- Zanini Nicola
- Zapardiel Ignacio
- Zapata Carlos Shiraishi
- Zarif Pierre
- Zaránd Attila
- Zehnder Philipp
- Zenger Serkan
- Zenha Horácio
- Zhu Michael Z. L.
- Ziemann Sebastian
- Zimak Danijela Mrazovac
- Zimak Zoran
- Zivkovic Dragana
- Zizzo Maurizio
- Zucker Benjamin
- Zwain Yasir
- Zyskowski Michael
- Ávila Clara Castro
- Älgå Andreas
- Çakici Mehmet Çaǧlar
- Çelik Enes
- Çelik Meryem Nur
- Özçay Necdet
- Şevik Hüsnü
- Šantak Goran
- Šimko Kristián
- Žatecký Jan
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2023
- Field of study
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
Three novel Pseudomonas phages isolated from composting provide insights into the evolution and diversity of tailed phages
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/05/2017
- Field of study
Abstract Background Among viruses, bacteriophages are a group of special interest due to their capacity of infecting bacteria that are important for biotechnology and human health. Composting is a microbial-driven process in which complex organic matter is converted into humus-like substances. In thermophilic composting, the degradation activity is carried out primarily by bacteria and little is known about the presence and role of bacteriophages in this process. Results Using Pseudomonas aeruginosa as host, we isolated three new phages from a composting operation at the Sao Paulo Zoo Park (Brazil). One of the isolated phages is similar to Pseudomonas phage Ab18 and belongs to the Siphoviridae YuA-like viral genus. The other two isolated phages are similar to each other and present genomes sharing low similarity with phage genomes in public databases; we therefore hypothesize that they belong to a new genus in the Podoviridae family. Detailed genomic descriptions and comparisons of the three phages are presented, as well as two new clusters of phage genomes in the Viral Orthologous Clusters database of large DNA viruses. We found sequences encoding homing endonucleases that disrupt a putative ribonucleotide reductase gene and an RNA polymerase subunit 2 gene in two of the phages. These findings provide insights about the evolution of two-subunits RNA polymerases and the possible role of homing endonucleases in this process. Infection tests on 30 different strains of bacteria reveal a narrow host range for the three phages, restricted to P. aeruginosa PA14 and three other P. aeruginosa clinical isolates. Biofilm dissolution assays suggest that these phages could be promising antimicrobial agents against P. aeruginosa PA14 infections. Analyses on composting metagenomic and metatranscriptomic data indicate association between abundance variations in both phage and host populations in the environment. Conclusion The results about the newly discovered and described phages contribute to the understanding of tailed bacteriophage diversity, evolution, and role in the complex composting environment
Identification of sixteen novel candidate genes for late onset Parkinson's disease
- Author
- Acampora D.
- Adarmes-Gómez Astrid D.
- Aguilar Miquel
- Aitkulova Akbota
- Akhmetzhanov Vadim
- Alcalay Roy N.
- Alvarez Ignacio
- Alvarez Victoria
- Bandres-Ciga Sara
- Barrero Francisco Javier
- Bergareche Yarza Jesús Alberto
- Bernal-Bernal Inmaculada
- Billingsley Kimberley
- Blauwendraat Cornelis
- Blazquez Marta
- Bonilla-Toribio Marta
- Botía Juan A.
- Boungiorno María Teresa
- Bras Jose
- Brice Alexis
- Brockmann Kathrin
- Bubb Vivien
- Buiza-Rueda Dolores
- Carrillo Fátima
- Carrión-Claro Mario
- Cerdan Debora
- Chelban Viorica
- Ciullo M.
- Clarimón Jordi
- Clarke Carl
- Compta Yaroslau
- Cookson Mark R.
- Corvol Jjean-Christophe
- Craig David W.
- D'Esposito M.
- Danjou Fabrice
- Di Giovannantonio Luca Giovanni
- Diez-Fairen Monica
- Dols-Icardo Oriol
- Duarte Jacinto
- Duran Raquel
- Escamilla-Sevilla Francisco
- Escott-Price Valentina
- Esposito T.
- Ezquerra Mario
- Faghri Faraz
- Feliz Cici
- Fernández Manel
- Fernández-Santiago Rubén
- Finkbeiner Steven
- Foltynie Thomas
- Gambardella Stefano
- Gan-Or Zin
- Garcia Ciara
- García-Ruiz Pedro
- Gasser Thomas
- Gialluisi Alessandro
- Gianfrancesco F.
- Gibbs J.Raphael
- Gomez Heredia Maria Jose
- Gonzalez-Aramburu Isabel
- Gorostidi Pagola Ana
- Guelfi Sebastian
- Guerreiro Rita
- Gómez-Garre Pilar
- Hardy John
- Hassin-Baer Sharon
- Hernandez Dena G.
- Heutink Peter
- Hoenicka Janet
- Holmans Peter
- Houlden Henry
- Iacoviello Licia
- Infante Jon
- Iwaki Hirotaka
- Jesús Silvia
- Jimenez-Escrig Adriano
- Kaishybayeva Gulnaz
- Kaiyrzhanov Rauan
- Kaiyrzhanov Rauan
- Karimova Altynay
- Kia Demis A.
- Kinghorn Kerri J.
- Koks Sulev
- Krohn Lynne
- Kulisevsky Jaime
- Labrador-Espinosa Miguel A.
- Leonard Hampton L.
- Lesage Suzanne
- Lewis Patrick
- Lombardi Alessia
- Lopez-Sendon Jose Luis
- Lovering Rruth
- Lubbe Steven
- Lungu Codrin
- López de Munain Arregui Adolfo
- Macias Daniel
- Majamaa Kari
- Manzoni Claudia
- Marinus Johan
- Marti Maria Jose
- Martinez Maria
- Martínez Torres Irene
- Martínez-Castrillo Juan Carlos
- Marín Juan
- Mata Marina
- Mencacci Niccolo E.
- Menéndez González Manuel
- Middlehurst Ben
- Mir Pablo
- Modugno Nicola
- Mok Kin Y.
- Mondragon Rezola Elisabet
- Morris Huw R.
- Morrison Karen E.
- Muñoz Esteban
- Méndez-del-Barrio Carlota
- Mínguez Adolfo
- Nalls Mike A.
- Narendra Derek
- Noyce Alastair J.
- Nutile Teresa
- Ojo Oluwadamilola O.
- Okubadejo Njideka U.
- Pagonabarraga Mora Javier
- Pastor Pau
- Perez Errazquin Francisco
- Periñán-Tocino Teresa
- Pietracupa Sara
- Pihlstrom Lasse
- Plun-Favreau Helen
- Quinn John
- R'Bibo Lea
- Reccia Mafalda Giovanna
- Reed Xylena
- Rizig Mie
- Rizzu Patrizia
- Robak Laurie
- Rouleau Guy A.
- Ruggiero Daniela
- Ruiz-Martínez Javier
- Ruz Clara
- Ryten Mina
- Sadykova Dinara
- Sanchez Rodriguez Antonio
- Scala Simona
- Scholz Sonja W.
- Schreglmann Sebastian
- Schulte Claudia
- Sharma Manu
- Shashkin Chingiz
- Shulman Joshua M.
- Sierra María
- Siitonen Ari
- Simeone A.
- Simón-Sánchez Javier
- Singleton Andrew B.
- Suarez-Sanmartin Esther
- Taba Pille
- Tabernero Cesar
- Tan Manuela
- Tartari Juan Pablo
- Tejera-Parrado Cristina
- Toft Mathias
- Tolosa Eduard
- Trabzuni Daniah
- Valldeoriola Francesc
- van Hilten Jacobus J.
- Van Keuren-Jensen Kendall
- Vargas-González Laura
- Vela Lydia
- Vives Francisco
- Williams Nigel
- Wood Nicholas W.
- Zharkynbekova Nazira
- Zharmukhanov Zharkyn
- Zholdybayeva Elena
- Zimprich Alexander
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2021
- Field of study
Altres ajuts: Italian Ministry of Health grant (RF 2019-12370224, GR2016-02362247); Italian Ministry of Economic Development (F/0009/00X26); Fondazione Umberto Veronesi.Background: Parkinson's disease (PD) is a neurodegenerative movement disorder affecting 1-5% of the general population for which neither effective cure nor early diagnostic tools are available that could tackle the pathology in the early phase. Here we report a multi-stage procedure to identify candidate genes likely involved in the etiopathogenesis of PD. Methods: The study includes a discovery stage based on the analysis of whole exome data from 26 dominant late onset PD families, a validation analysis performed on 1542 independent PD patients and 706 controls from different cohorts and the assessment of polygenic variants load in the Italian cohort (394 unrelated patients and 203 controls). Results: Family-based approach identified 28 disrupting variants in 26 candidate genes for PD including PARK2, PINK1, DJ-1(PARK7), LRRK2, HTRA2, FBXO7, EIF4G1, DNAJC6, DNAJC13, SNCAIP, AIMP2, CHMP1A, GIPC1, HMOX2, HSPA8, IMMT, KIF21B, KIF24, MAN2C1, RHOT2, SLC25A39, SPTBN1, TMEM175, TOMM22, TVP23A and ZSCAN21. Sixteen of them have not been associated to PD before, were expressed in mesencephalon and were involved in pathways potentially deregulated in PD. Mutation analysis in independent cohorts disclosed a significant excess of highly deleterious variants in cases (p = 0.0001), supporting their role in PD. Moreover, we demonstrated that the co-inheritance of multiple rare variants (≥ 2) in the 26 genes may predict PD occurrence in about 20% of patients, both familial and sporadic cases, with high specificity (> 93%; p = 4.4 × 10). Moreover, our data highlight the fact that the genetic landmarks of late onset PD does not systematically differ between sporadic and familial forms, especially in the case of small nuclear families and underline the importance of rare variants in the genetics of sporadic PD. Furthermore, patients carrying multiple rare variants showed higher risk of manifesting dyskinesia induced by levodopa treatment. Conclusions: Besides confirming the extreme genetic heterogeneity of PD, these data provide novel insights into the genetic of the disease and may be relevant for its prediction, diagnosis and treatment
NEOTROPICAL CARNIVORES: a data set on carnivore distribution in the Neotropics
- Author
- Abra Fernanda Delborgo
- Abreu Ribeiro Edvandro
- Age Stefani Gabrieli
- Aguiar Erick Francisco
- Aguiar Gabriel Lima
- Aguiar Leonardo Dos Santos
- Akkawi Paula
- Albanesi Sebastian
- Alberici Vinicius
- Alencar Raony de Macêdo
- Alexandrino Eduardo Roberto
- Almeida Meyline Oliveira
- Althoff Sérgio Luiz
- Alvarez Martín R
- Alves Prado Helena
- Alves Giselle Bastos
- Alves Rafael Souza Cruz
- Alves Romulo Romeu Nobrega
- Alves-Eigenheer Milene
- Anaguano-Yancha Fernando
- Andrade da Silva Maria Augusta
- Andrade Bruna da Silva
- Andrade Rúbia Santana
- Antas Paulo de Tarso Zuquim
- Antunes Andre Pinassi
- Aquino Ana Carla Medeiros Morato
- Araujo Raylenne da Silva
- Araújo Luciana
- Araújo Rodrigo Paulo da Cunha
- Araújo Valquíria Cabral
- Arimoro Omolabake Alhambra
- Arrabal Juan Pablo
- Arroyo-Gerala Paulina
- Assis Jasmine Resende
- Assis Julia Camara
- Astete Samuel
- Astúa Diego
- Auricchio Paulo
- Ayala Crespo Guido Marcos
- Bacellar Ana Elisa de Faria
- Bager Alex
- Bailey Larissa L
- Banhos Aureo
- Barbier Eder
- Barbosa Larissa de Nazaré Barros
- Barreto Larissa Nascimento
- Barros Maria Claudene
- Barros Marília A S
- Barros-Battesti Darci Moraes
- Bassini-Silva Ricardo
- Bastazini Vinicius A G
- Batista Graziele Oliveira
- Bazilio Sergio
- Beca Gabrielle
- Beduschi Julia
- Behling Greici Maia
- Beisiegel Beatriz de Mello
- Beltrão Mayara Guimarães
- Beltrão-Mendes Raone
- Benavalli Letícia
- Benchimol Maíra
- Bercê William
- Bergallo Helena de Godoy
- Bergel Mariano Maudet
- Bernardi Itiberê
- Bernardo Christine Steiner S
- Bernardo Rodrigo
- Bertagni de Camargo Bruna
- Bertassoni Alessandra
- Bertoldi Ariane Teixeira
- Bessa Rafael
- Bezerra Alexandra Maria Ramos
- Bianchi Rita de Cassia
- Bocchiglieri Adriana
- Bogoni Juliano André
- Bonanomi Juliana
- Bonfim Fernando César Gonçalves
- Bonjorne Lilian
- Bordallo Samanta Uchôa
- Borges Luiz Henrique Medeiros
- Bovo Alex Augusto Abreu
- Bowler Mark
- Braga Caryne
- Brandão Vecchi Maurício
- Bravata de la Cruz Yaribeth
- Braz Vivian da Silva
- Brennand Pamella
- Bubadué Jamile
- Buitenwerf Robert
- Burs Kathrin
- Buscariol Daiane
- Buschiazzo Martin
- Cabral Hugo
- Calaça Analice Maria
- Calouro Armando Muniz
- Camara Edeltrudes Maria Valadares Calaça
- Camargo Paulo H S A
- Campelo Ana Kellen Nogueira
- Campos Krauer Juan Manuel
- Canassa Nathália Fernandes
- Cantagallo Devids Camila
- Canteri Adriano
- Caribé Grando Raquel L S C
- Carrano Eduardo
- Carreira Daiane Cristina
- Carrillo-Percastegui Samia E
- Carrizo María Celina
- Cartes Jose Luis
- Carvalho Jr, Elildo Alves Ribeiro
- Carvalho Andrea Siqueira
- Carvalho-Leite Ludimila Juliele
- Castro Érika Paula
- Catenacci Lilian
- Cavalcante Thiago
- Cavarzere Vagner
- Cervini Marcelo
- Cezila Beatriz Azevedo
- Chacón Pacheco Julio Javier
- Chagas Renata
- Charre-Medellin Juan Felipe
- Chaves Dos Santos José Carlos
- Chaves Flávia Guimarães
- Cheida Carolina Carvalho
- Chein Alonso André
- Cherem Jorge José
- Chiarello Adriano Garcia
- Chávez Cuauhtémoc
- Chávez-Congrains Karla
- Chávez-González Edgar
- Cinta Claudia Cristina
- Ciocheti Giordano
- Cobra Priscilla De Paula Andrade
- Coelho Igor Pfeifer
- Concone Henrique Villas Boas
- Contreras Palma Kamila Marianne
- Contreras-Moreno Fernando M
- Cordeiro José
- Cordeiro-Estrela Pedro
- Corrêa Matheus Rocha Jorge
- Costa Braga David
- Costa Lopes Alexandre Martins
- Costa Alan Nilo
- Costa Claudia Guimaraes
- Costa Francys Emanuelle
- Costa Jociel Ferreira
- Costa Rômulo
- Costa Sebastián Andrés
- Coutinho Raphaella
- Cravino Mol Alexandra
- Cronemberger Cecilia
- Cruz Paula
- Cueva Loachamín Rubén Darío
- Cullen Jr, Laury
- Cunha Costa Ana Raissa
- Cáceres Nilton C
- D'Bastiani Elvira
- da Cunha Cristina Jaques
- da Cunha Rogério Grassetto Teixeira
- da Rosa Clarissa Alves
- da Silva André Luiz Ferreira
- da Silva Leonardo Henrique
- da Silva Marcelo
- da Silva Murillo Prado
- da Silva Rafaela Aparecida
- da Silva Raquel Costa
- Dahmer Lais Camila
- Dantas José Oliveira
- de Albuquerque Anna Carolina Figueiredo
- de Albuquerque Natasha Moraes
- de Almeida Curi Nelson Henrique
- de Almeida Lana Resende
- de Almeida-Rocha Juliana Monteiro
- De Angelo Carlos
- de Azevedo Fernanda Cavalcanti
- de Barros Barban Ananda
- de Barros Fernanda Cristina
- de Camargo E Timo Thiago Philipe
- de Castilho Pedro Volkmer
- de Freitas Evellyn Borges
- De la Maza Javier
- de la Peña-Cuéllar Erika
- de la Sancha Noé U
- de la Torre J Antonio
- de Lima Camilla Angélica
- de Lima Camilo Ribeiro
- De Lima Natani Da Silva
- de Matos Jose Roberto
- de Melo Fabiano Rodrigues
- de Oliveira Ramonna
- de Paula Almir
- de Paula Lívia Maria
- de Paula Milton
- de Paula Rogério Cunha
- de Sousa E Silva Júnior José
- de Souza Agnis Cristiane
- de Souza Rafael Cerqueira Castro
- de Thoisy Benoit
- De-Carvalho Crizanto Brito
- Dechner Andrea
- Deffaci Ângela Camila
- Del Castillo Hugo Fernando
- Del Vechio Christine
- Denkiewicz Natalia Mariana
- Devlin Allison L
- Di Bitetti Mario S
- Dias Douglas de Matos
- Dias Leticia Coutinho Sangy
- Diaz-Santos Fabricio
- Didier Karl
- do Nascimento Fabio Oliveira
- do Rosário Maria Cristina Ferreira
- Dos Reis Júnior José Clemensou
- Dos Santos Junior Marcelo Augusto
- Duarte Gabriela Teixeira
- Duarte Herbert
- Duarte José Maurício Barbanti
- Durigan Carlos Cesar
- Durães Rayssa Mainette Nantes
- Dáttilo Wesley
- Díaz-Santos Fabio Gabriel
- Eaton Donald P
- Eizirik Eduardo
- Endo Whaldener
- Eriksson Alan
- Ermenegildo Hiago
- Espinosa Caroline da Costa
- Espinosa Santiago
- Espíndola Hack Robson Odeli
- Falconi Nereyda
- Faria Peres Pedro Henrique
- Faria Michel Barros
- Faria Rhayssa Terra
- Farias Danilo Augusto
- Feijó Anderson
- Fernandes Arthur
- Fernandes Maria Emília Avelar
- Fernandes-Ferreira Hugo
- Fernández Ramirez Sixto
- Ferraz Daniel da Silva
- Ferraz Katia M P M B
- Ferreguetti Atilla Colombo
- Ferreira Paulino Neto Hipólito
- Ferreira Arystene Nicodemo
- Ferreira Paula Modenesi
- Fieker Carolline Zatta
- Figueiredo Marcos de Souza Lima
- Figuerêdo Duarte Moraes Marcela
- Fischer Erich
- Flesher Kevin
- Fleytas Jover Maria Del Carmen
- Fonseca Carlos
- Forero-Medina German
- Fornitano Larissa
- Fraga Elmary da Costa
- Fragoso Carlos Eduardo
- Franceschi Ingridi Camboim
- Francisco Beatriz da Silva de Souza
- França Bruno Rodrigo de Albuquerque
- França Frederico G R
- Freitas-Junior Mozart Caetano
- Friedeberg Diana
- Fróes Rodrigo Medina
- Fusco-Costa Roberto
- Gaboardi Viviane Telles Rodrigues
- Galetti Jr, Pedro Manoel
- Galetti Mauro
- Galiano Daniel
- Galliez Maron
- Garcia-Anleu Rony
- García-Olaechea Alvaro
- Gaspar Denise Alemar
- Gaspar Lucas Pacciullio
- Gatica Ailin
- Gatti Andressa
- Gestich Carla Cristina
- Gilmore Michael P
- Giné Gastón Andrés Fernandez
- Giovanelli João Gabriel Ribeiro
- Girardi Fabiane
- Godoi Mauricio Neves
- Gomes Ana Paula Nascimento
- Gomes Felipe Bittioli R
- Gomes Leonardo de Paula
- Gomez Vinassa Maria Laura
- Gompper Matthew E
- Gondim Tayana Mendonça da Silva
- González Enrique
- González-Gallina Alberto
- Gonçalves da Silva Lucas
- Gonçalves Fernando
- Gonçalves Pablo Rodrigues
- Gouvea Jéssica Abonizio
- Graipel Maurício Eduardo
- Grossel Laís Aline
- Grotta-Neto Francisco
- Gräbin Diogo Maia
- Guaragni Samara Arsego
- Guedes da Silva Fernanda
- Guedes Layme Viviane Maria
- Guenther Mariana
- Guijosa-Guadarrama Emiliano
- Guimarães Luiza Neves
- Gurgel-Filho Newton Mota
- Haberfeld Mario
- Hannibal Wellington
- Hartmann Marilia Teresinha
- Hartmann Paulo Afonso
- Hartz Sandra Maria
- Hass Adriani
- Hass Carlos
- Hasui Érica
- Hatakeyama Richard
- Hatano Fernanda Martins
- Hawes Joseph E
- Heliodoro Gabriela
- Hermann Andiara Paula
- Herrera Victoria Ana María
- Herrera Heitor Miraglia
- Hidalgo-Mihart Mircea G
- Hilário Renato Richard
- Hinojosa Javier
- Hofmann Gabriel Selbach
- Hoogesteijn Rafael Jan
- Huerta Maria Emilia
- Hufnagel Ludmila
- Hurtado Cindy Meliza
- Iezzi María Eugenia
- Ilha Júlia
- Ingberman Bianca
- Isasi-Catalá Emiliana
- Islas Camila Alvez
- Iwakami Victor
- Jacinavicius Fernando de Castro
- Jardim Marcia Maria de Assis
- Jenkins Clinton N
- Jesus de la Cruz Alejandro
- Jesus Anamélia Souza
- Jordao Juliana
- Jorge Maria Luisa S P
- Jorge Rodrigo Silva Pinto
- Juarez Keila Macfadem
- Just João Paulo Gava
- Juárez Rugieri
- Jácomo Anah Tereza de Almeida
- Kaizer Mariane
- Kanaan Vanessa Tavares
- Kanda Claudia Zukeran
- Karlovic Thamíris Christina
- Kasper Carlos Benhur
- Keesen Ferreira Fabíola
- Keuroghlian Alexine
- Keuroghlian-Eaton Sean
- Konzen Maurício Quoos
- Kubiak Bruno Busnello
- Lacerda Ana Cristyna Reis
- Lamattina Daniela
- Landis Mariana Bueno
- Lanna Andre Monnerat
- Lautenschlager Laís
- Leite de Oliveira Márcio
- Leles Bruno
- Lemos Frederico Gemesio
- Lemos Hudson Macedo
- Leuchtenberger Caroline
- León Pérez Rodrigo Raúl
- Lima da Silva Marina
- Lima Edson de Souza
- Lima Marcela Guimarães Moreira
- Lizcano Diego J
- Lombardi Pryscilla Moura
- Longo Jose Milton
- Lopes Cíntia M
- Loretto Diogo
- Lorini Maria Lucia
- Luiz Micheli Ribeiro
- Luna Cecília Licarião
- Luna Pedro
- Luza André Luís
- Lyra Luiz Henrique
- López-Fuerte Cristina Fabiola
- Maccarini Thiago
- Machado da Silva Douglas
- Machado Cauanne Iglesias Campos
- Machado Sávio Augusto de Souza
- Magalhães Laura Martins
- Magalhães Rodolfo Assis
- Magioli Marcelo
- Mangione Antonio Marcelo
- Mantovani Jose Eduardo
- Marinho Jorge Reppold
- Marinho Paulo Henrique
- Marinho-Filho Jader
- Marques Costa Leonardo
- Marques Leandro
- Marques Marinêz Isaac
- Martello Felipe
- Martin Cristiane
- Martin Paula Sanches
- Martinez Jaime
- Martins Maísa Ziviani Alves
- Martins Paulo Wesley
- Martins Rogério
- Martins Waldney Pereira
- Martínez Lanfranco Juan Andrés
- Martínez Nambo Erik Daniel
- Martínez Retta Lucía
- Massara Rodrigo Lima
- Mata Julia Carolina
- Matos Rayanne Gama
- Medeiro Akyllam Zoppi
- Melo Geruza L
- Melo Isabel
- Melo Vanessa Lazaro
- Melo-Dias Mateus
- Mendes Pontes Antonio Rossano
- Mendes Sergio Lucena
- Mendonça André Faria
- Mendonça Eloisa Neves
- Mendonça Leonardo Siqueira
- Metzger Jean Paul
- Michalski Fernanda
- Miotto Renata
- Miranda João
- Mongelli Melissa
- Monroy-Vilchis Octavio
- Montanarin Anelise
- Monteiro André
- Monterrubio Tiberio Cesar
- Montes Martin Alejandro
- Morais Kimberly Danielle Rodrigues
- Morandi Maria Elisa de Freitas
- Morato Ronaldo Gonçalves
- Moreira Ramírez José Fernando
- Moreira Danielle Oliveira
- Moreira Leandro Santana
- Moreira Tainah Cruz
- Moreli Fantacini Felipe
- Moreno Daniele Janina
- Morini Maria Santina
- Moura André Luis Botelho
- Moura Mauricio O
- Mourthe Italo
- Mourão Guilherme de Miranda
- Munhoes Leticia Prado
- Muylaert Renata Lara
- Nagy-Reis Mariana
- Nakano-Oliveira Eduardo
- Napiwoski Silvio Junior
- Nascimento Lorena Anne
- Neves Bianca Dos Santos
- Nobre Andrezza Bellotto
- Nobre Rodrigo de Almeida
- Nobrega Rodrigo Affonso de Albuquerque
- Nodari Joana Zorzal
- Novaes Claudio Leite
- Novaro Andres Jose
- Nunes André Valle
- Nunez-Regueiro Mauricio
- Nuñez María Beatriz
- Ochoa Ana Cecilia
- Olifiers Natalie
- Oliveira Santos Luiz Gustavo Rodrigues
- Oliveira Jasmim Felipe
- Oliveira Leonardo de Carvalho
- Oliveira Luiz Flamarion
- Oliveira Marcela Alvares
- Oliveira Valeska Buchemi
- Oliveira-Bevan Isabella
- Olímpio Ana Priscila Medeiros
- Onofrio Valeria Castilho
- Orsini Vinícius Santana
- Ortiz-Moreno Martha Lucia
- Oshima Júlia Emi de Faria
- Paglia Adriano Pereira
- Pagoto Anderson
- Pagotto Renata Valls
- Palacios Perez Jaime Xavier
- Palmeira Francesca Belem Lopes
- Palomares Francisco
- Pandini Favoretti João Paulo
- Paolino Roberta Montanheiro
- Pardo Maximiliano Víctor
- Paschoal Ana Maria de Oliveira
- Pasqualotto Nielson
- Passamani Marcelo
- Passos Fernando C
- Patiu Fabio Mello
- Pays Olivier
- Pedroni Fernando
- Pedrosa Felipe
- Pedroso Rayssa Faria
- Pedó Ezequiel
- Penteado Marcel José Franco
- Percequillo Alexandre
- Pereira Mendes Calebe
- Pereira Adriele Aparecida
- Pereira Fabiane de Aguiar
- Pereira Taiguã Corrêa
- Pereira-Ribeiro Juliane
- Pereira-Silva Brenda
- Perera-Romero Lucy E
- Peres Carlos A
- Perilli Miriam Lucia Lages
- Perillo Lucas Neves
- Peroni Nivaldo
- Pessoa da Silva Felipe
- Peña-Mondragón Juan L
- Peñuela Mora María Cristina
- Pianca Camila
- Picinatto Filho Vilmar
- Pincheira-Ulbrich Jimmy
- Pinheiro Shery Duque
- Pinto Antonio Millas Silva
- Piovezan Ubiratan
- Pires José Salatiel Rodrigues
- Pires Ricardo Araújo
- Polisar John
- Polli Daiana Jeronimo
- Porfirio Grasiela Edith de Oliveira
- Potrich Ana Paula
- Powell George V N
- Prado Paulo Inácio
- Prestes Nêmora Pauletti
- Priante Camila Fátima
- Prist Paula Ribeiro
- Puertas Fernando Henrique
- Pérez-Torres Jairo
- Pônzio Marcella do Carmo
- Quatrocchi Maira Giuliana
- Querido Luciano Carramaschi de Alagão
- Quigley Howard
- Quintilham Lucas
- Rajão Henrique
- Ramalho Emiliano Esterci
- Ramalho Fernanda do Passo
- Ramis Segura Lucas
- Ramos Lima Saulo
- Ramos Pereira Maria João
- Rampim Lilian Elaine
- Ramírez Pinto Fredy
- Rechenberg Elisabete
- Reis Matheus Gonçalves
- Renaud Pierre-Cyril
- Reyna-Hurtado Rafael
- Rezende Bernardo Luis Renato
- Rezende Guilherme Zamarian
- Rezende Lucas Rodrigo
- Ribeiro de Andrade Gabrielle
- Ribeiro Adauto de Souza
- Ribeiro Igor Kintopp
- Ribeiro Milton C
- Ribeiro Otávio Santi
- Ribeiro Renan Lieto Alves
- Ribeiro Yuri Geraldo Gomes
- Rigacci Eduardo Delgado
- Rivero Marina
- Rocha Carlos Frederico Duarte
- Rocha Ednaldo Cândido
- Rocha Eliana César Laranjeira Duarte
- Rocha Erick Sekiama
- Rocha Fabiana Lopes
- Rocha Joedison
- Rocha Patrício
- Rocha Vlamir José
- Rodrigues Camila
- Rodrigues Flavio Henrique Guimarães
- Rodrigues Manoel
- Rodrigues Thiago Ferreira
- Rodriguez Castro Karen Giselle
- Rodriguez-Pulido Jose Ariel
- Rogeri Patricia
- Rohe Fabio
- Roig Henrique Llacer
- Rojas Bonzi Viviana B
- Rojas Lucia Nathaly Stefany
- Rolim Anderson Claudino
- Romagna Rafael Spilere
- Roque Fabio de Oliveira
- Rosa Augusto Lisboa Martins
- Rossi Junior João Luiz
- Rudolf Juan Carlos
- Ruffino Paulo Henrique Peira
- Ruiz Carmen Elena Barragán
- Ruiz-Esparza Juan
- Saito Erica Naomi
- Salles Munerato Marina
- Salvador Carlos Henrique
- Sampaio Ricardo
- Santana Gindomar Gomes
- Santos Almeida Rony Peterson
- Santos Bruna Silva
- Santos Cyntia Cavalcante
- Santos Eduardo Marques
- Santos Fernanda da Silva
- Santos Filipe Martins
- Santos Joyce Gonçalves
- Santos Paloma Marques
- Saranholi Bruno Henrique
- Sarasola José Hernán
- Sarmento Pedro
- Sartor Caroline Charão
- Sartorello Leonardo
- Sartorello Ricardo
- Scabin Andressa Barbara
- Scarascia Pietro Oliveira
- Schuchmann Karl L
- Schutte Michel
- Seber Samile
- Secco Helio
- Seibert Jardel Brandão
- Seixas Cristiana Simão
- Sekiama Margareth L
- Setz Eleonore
- Severo Magnus Machado
- Silva Diego Afonso
- Silva Ramon Lima
- Silva Wesley R
- Silveira Dos Santos Juliana
- Silveira Jana Rangel
- Silveira Leandro
- Silveira Marcos
- Silvestre Saulo Meneses
- Siviero Maria Brunini
- Soares Fábio Angelo Melo
- Souto Glauber Henrique Borges de Oliveira
- Souza Andiara Silos Moraes de Castro E
- Souza Franco Leandro
- Souza Jesus Rodrigues Domingos
- Souza-Alves João Pedro
- Sponchiado Jonas
- Srbek-Araujo Ana Carolina
- Strier Karen B
- Svenning Jens-Christian
- Sánchez Amadeo
- Sánchez-Lalinde Catalina
- Talamoni Sonia Aparecida
- Tavares Davi Castro
- Tavares Mariana Silva
- Tedesco Carla Denise
- Thompson Jeffrey James
- Thornton Daniel
- Tirelli Flavia Pereira
- Tobler Mathias W
- Toledo Gustavo Alves da Costa
- Tomas Walfrido Moraes
- Tomasi Roberto Junior
- Tomazzoni Ana Cristina
- Tonetti Vinicius Rodrigues
- Torres Parahyba Campos Bruno Augusto
- Torres Natalia Mundim
- Tortato Fernando Rodrigo
- Tortato Marcos Adriano
- Towns Valeria
- Trigo Tatiane Campos
- Trinca Cristiano Trapé
- Trovati Roberto Guilherme
- Twardowsky Ramalho Bonikowski Renata
- Ubaid Flávio Kulaif
- Vale Mariana M
- Vale Victor
- Valenzuela Leonor Adriana
- Varela Diego M
- Velez-Garcia Felipe
- Velilla Marianela
- Venancio José Otávio
- Venticinque Eduardo Martins
- Verdade Luciano Martins
- Verona Carlos Eduardo
- Viana Diego Carvalho
- Vieira Carlos Leonardo
- Vieira Marcus Vinícius
- Vilas Boas Flávio Eduardo
- Villalba Laura Magnolia
- Villalva Pablo
- Villani João Paulo
- Villarroel Glenda Jéssica
- Villegas Marcelo Alejandro
- Viscarra Siñani Maria Estela
- Vogliotti Alexandre
- Wallace Robert
- Wilson Fernandes Geraldo
- Xavier da Silva Marina
- Xavier Mariana Sampaio
- Yamane Marcelo Hideki
- Yanosky Alberto A
- Zago da Silva Luciana
- Zanella Noeli
- Zanin Marina
- Zaniratto Cristiane Patrícia
- Zanoni Juliani Bruna
- Zanón-Martínez Juan Ignacio
- Zapata-Ríos Galo
- Zecchini Gebin João Carlos
- Ziegler Jörn
- Zárate-Castañeda Claudia Paola
- Zúñiga Hartley Alfonso Christopher
- Álvarez Solas Sara
- Publication venue
- 'Wiley'
- Publication date
- 01/11/2020
- Field of study
Mammalian carnivores are considered a key group in maintaining ecological health and can indicate potential ecological integrity in landscapes where they occur. Carnivores also hold high conservation value and their habitat requirements can guide management and conservation plans. The order Carnivora has 84 species from 8 families in the Neotropical region: Canidae; Felidae; Mephitidae; Mustelidae; Otariidae; Phocidae; Procyonidae; and Ursidae. Herein, we include published and unpublished data on native terrestrial Neotropical carnivores (Canidae; Felidae; Mephitidae; Mustelidae; Procyonidae; and Ursidae). NEOTROPICAL CARNIVORES is a publicly available data set that includes 99,605 data entries from 35,511 unique georeferenced coordinates. Detection/non-detection and quantitative data were obtained from 1818 to 2018 by researchers, governmental agencies, non-governmental organizations, and private consultants. Data were collected using several methods including camera trapping, museum collections, roadkill, line transect, and opportunistic records. Literature (peer-reviewed and grey literature) from Portuguese, Spanish and English were incorporated in this compilation. Most of the data set consists of detection data entries (n = 79,343; 79.7%) but also includes non-detection data (n = 20,262; 20.3%). Of those, 43.3% also include count data (n = 43,151). The information available in NEOTROPICAL CARNIVORES will contribute to macroecological, ecological, and conservation questions in multiple spatio-temporal perspectives. As carnivores play key roles in trophic interactions, a better understanding of their distribution and habitat requirements are essential to establish conservation management plans and safeguard the future ecological health of Neotropical ecosystems. Our data paper, combined with other large-scale data sets, has great potential to clarify species distribution and related ecological processes within the Neotropics. There are no copyright restrictions and no restriction for using data from this data paper, as long as the data paper is cited as the source of the information used. We also request that users inform us of how they intend to use the data
Searching for VHE gamma-ray emission associated with IceCube neutrino alerts using FACT, H.E.S.S., MAGIC, and VERITAS
- Author
- Abbasi Rasha
- Abdalla Hassan
- Acciari Victor A.
- Ackermann Markus
- Adams Jenni
- Aguilar Juanan
- Aharonian Felix
- Ahlers M.
- Ahrens Maryon
- Ait-Benkhali Faical
- Alispach Cyril Martin
- Alves Junior Antonio Augusto
- Amin Najia Moureen Binte
- An Rui
- Andeen Karen
- Anderson Tyler
- Anguener Oguzhan
- Ansoldi Stefano
- Anton Gisela
- Antonelli Lucio Angelo
- Arbet Engels Axel
- Arcaro Cornelia
- Arguelles Carlos
- Armand Celine
- Armstrong Tom
- Artero Manuel
- Asano Katsuaki
- Ashida Yosuke
- Ashkar Halim
- Axani Spencer
- Baack Dominik
- Babic Ana
- Backes Michael
- Baghmanyan Vardan
- Bai Xinhua
- Balagopal V. Aswathi
- Balbo Matteo
- Baquero Andrés
- Barbano Anastasia Maria
- Barbosa Martins Victor
- Barnacka Anna
- Barnard Monica
- Barres de Almeida Ulisses
- Barrio Juan Abel
- Barwick S. W.
- Bastian Benjamin
- Basu Vedant
- Batković Ivana
- Batzofin Rowan
- Baur Sebastian
- Bay R. C.
- Beatty J. J.
- Becerra Gonzalez Josefa
- Becherini Yvonne
- Becker Tjus Julia
- Becker K. -H.
- Bednarek Wlodek
- Bellenghi Chiara
- Bellizzi Lorenzo
- BenZvi Segev
- Berge David
- Berley D.
- Bernardini Elisa
- Bernardos Maria-Isabel
- Bernlöhr Konrad
- Berti Alessio
- Besenrieder Jürgen
- Besson D. Z.
- Bhattacharyya Wrijupan
- Bi Baiyang
- Bigongiari Ciro
- Biland Adrian
- Binder Gary
- Bindig Daniel
- Blanch Oscar
- Blaufuss E.
- Blot Summer
- Boddenberg Matthias
- Boisson Catherine
- Bolmont Julien
- Bonnoli Giacomo
- Bontempo Federico
- Borowka Jurgen
- Boser S.
- Bosnjak Zeljka
- Botner Olga
- Bottcher Jakob
- Bourbeau Etienne
- Bökenkamp Hendrik
- Böttcher Markus
- Bradascio Federica
- Braun J.
- Bretz Thomas
- Breuhaus Mischa
- Bron Stephanie
- Brose Robert
- Brostean-Kaiser Jannes
- Browne Sally-Ann
- Brun Francois
- Bulik Tomasz
- Burgman Alexander
- Burley Ryan
- Busetto Giovanni
- Buss Jens
- Busse Raffaela
- Bylund Thomas
- Campana Michael
- Cangemi Floriane
- Carnie-Bronca Erin
- Caroff Sami
- Carosi Roberto
- Casanova Sabrina
- Catalano Jaqueline
- Ceribella Giovanni
- Cerruti Matteo
- Chai Yating
- Chambery Pauline
- Chand Tej Bahadur
- Chen Andrew
- Chen Chujie
- Chilingarian Ashot Agassi
- Chirkin Dmitry
- Choi Koun
- Cikota Stefan
- Clark Bryanlee
- Clark Kenneth
- Classen Lew
- Colak Sidika Merve
- Coleman Alan
- Collin Gabriel
- Colombo Eduardo
- Conrad J. M.
- Contreras Jose Luis
- Coppin Paul
- Correa Pablo
- Cortina Juan
- Cotter Garret
- Covino Stefano
- Cowen D. F.
- Cross R.
- Curlo Malgorzata
- D'Amico Giacomo
- D'Elia Valerio
- Da Vela Paolo
- Damascene Mbarubucyeye Jean
- Dappen Christian
- Dave Pranav
- Davids Hambeleleni
- Davids Isak Delberth
- Davies James
- Dazzi Francesco
- De Angelis Alessandro
- de Bony Mathieu
- DE CLERCQ Catherine
- De Lotto Barbara
- De Ridder Sam
- de Vries Krijn
- de Wasseige Gwenhaël
- De With Meike
- DeLaunay James
- Delfino Manuel
- Delgado Mendez Carlos
- Delgado Jordi
- Dembinski Hans
- Deoskar Kunal
- Depaoli Davide
- Desai Abhishek
- Desiati Paolo
- Devin Justine
- DeYoung Tyce
- Dharani Sukeerthi
- Di Pierro Federico
- Di Venere Leonardo
- Diaz Alejandro
- Diaz-Velez Juan Carlos
- Dittmer Markus
- Djannati-Ataï Arache
- Dmytriev Anton
- Do Souto Espiñeira Elia
- Dominis Prester Dijana
- Donath Axel
- Donini Alice
- Dorner Daniela
- Doro Michele
- Doroshenko Victor
- Dreyer Lente
- Du Plessis Louis
- Duffy Connor
- Dujmovic Hrvoje
- Dunkman Matt
- DuVernois Michael
- Dvorak Emily
- Egberts Kathrin
- Ehrhardt Thomas
- Einecke Sabrina
- Eisenberger Laura
- Eller Philipp
- Elsaesser Dominik
- Emery Gabriel
- Engel Ralph
- ERNENWEIN Jean-Pierre
- Erpenbeck Hannah
- Evans John
- Evenson P. A.
- Fallah Ramazani Vandad
- Fan Kwok Lung
- Fattorini Alicia
- Fazely A. R.
- Fegan Steven
- Feijen Kirsty
- Fiasson Armand
- Fichet de Clairfontaine Gaëtan
- Fiedlschuster Sebastian
- Fienberg Aaron
- Filimonov Kirill
- Finley Chad
- Fischer Leander
- Fonseca Maria Victoria
- Font Lluis
- Fontaine Gerard
- Fox Derek B
- Franckowiak Anna
- Frans Lott
- Friedman Elizabeth
- Fritz Alexander
- Fruck Christian
- Fuessling Matthias
- Fukami Satoshi
- Fukazawa Yasushi
- Funk Stefan
- Furst Philipp
- Gabici Stefano
- Gaisser T. K.
- Gallagher Jay
- Gallant Yves
- Ganster Erik
- Garcia Alfonso
- García López Ramon J.
- Garczarczyk Markus
- Garrappa Simone
- Gasparyan Sargis
- Gaug Markus
- Gerhardt L.
- Ghadimi Ava
- Ghafourizade Shahede
- Giavitto Gianluca
- Giglietto Nicola
- Giordano Francesco
- Giunti Luca
- Glaser Christian
- Glauch Theo
- Glawion Dorit
- Glicenstein Jean-Francois
- Gliwny Pawel
- Glusenkamp Thorsten
- Godinovic Nikola
- Goldschmidt A.
- Gonzalez Javier
- Goswami Sreetama
- Grant Darren
- Green David
- Green Jarred Gershon
- Grégoire Timothée
- Griswold Spencer
- Grondin Marie-Hélène
- Gunduz Mehmet
- Günther Christoph
- Ha Minh Martin
- Haack Christian
- Hadasch Daniela
- Hahn Alexander
- Hallgren Allan
- Halliday R.
- Halve L.
- Halzen F.
- Hanson Kael
- Hardin John
- Harnisch Alexander A.
- Hattingh Sumari
- Haungs Andreas
- Haupt Maria
- Hauser Simon
- Hebecker Dustin
- Heckmann Lea
- Helbing K.
- Henningsen Felix
- HERMANN German
- Herrera Javier
- Hettinger Emma C.
- Hickford Stephanie
- Hignight Joshua
- Hildebrand Dorothee
- Hill Colton
- Hill G. C.
- Hinton Jim
- Hoang John
- Hoffman Kara
- Hoffmann Ruth
- Hofmann Werner
- Hoinka Tobias
- Hoischen Clemens
- Hokanson-Fasig Benjamin
- Holch Tim
- Holler Markus
- Horns Dieter
- Hoshina K.
- Hörbe Mario
- Hrupec Dario
- Huang Feifei
- Huang Zhi-Qiu
- Huber David
- Huber Matthias
- Huber Thomas
- Hultqvist Klas
- Hunnefeld Mirco
- Hussain Raamis
- Hütten Moritz
- In Seongjin
- Inada Tomohiro
- Iotov Roman
- Iovine Nadège
- Ishihara Aya
- Ishio Kazuma
- Iwamura Yuki
- Jamrozy Marek
- Jankowsky Felix
- Jansson Matti
- Japaridze George
- Jeong Minjin
- Jiménez Martínez Irene
- Jin Weidong
- Jones Ben
- Jormanainen Jenni
- Joshi Vikas
- Jouvin Léa
- JUNG Ira
- Kalenski Adelina
- Kang Donghwa
- Kang Woosik
- Kang Xinyue
- Kappes Alexander
- Kappesser David
- Karg Timo
- Karjalainen Marie
- Karl Martina
- Karle A.
- Kasai Eli
- Katarzynski Krzysztof
- Katz U.
- Katz Ulì
- Kauer M.
- Kellermann Moritz
- Kelley J. L.
- Kerszberg Daniel
- Khangulyan Dmitry
- Kheirandish Ali
- Khelifi Bruno
- Kin Ken'ichi
- Kintscher Thomas
- Kiryluk Joanna
- Klein Spencer
- Klepser Stefan
- Kluzniak Wlodek
- Kobayashi Yukiho
- Koirala Ramesh
- Kolanoski Hermann
- Komin Nukri
- Konno Ruslan
- Kontrimas Tomas
- Kopke Lutz
- Kopper Claudio
- Kopper Sandro
- Kosack Karl
- Koskinen D. J.
- Kostunin Dmitriy
- Koundal Paras
- Kovacevich Michael
- Kowalski Marek
- Kozynets Tetiana
- Kreter Michael
- Kubo Hidetoshi
- Kukec Mezek Gašper
- Kun Emma
- Kundu Anu
- Kurahashi Naoko
- Kushida Junko
- Lad Neha
- Lagunas Gualda Cristina
- Lamanna Giovanni
- Lamastra Alessandra
- Lanfranchi Justin
- Larson Michael J
- Lauber Frederik Hermann
- Lazar Jeffrey
- Le Stum Sébastien
- Lee Jiwoong
- LELAS Damir
- Lemiere Anne
- Lemoine-Goumard Marianne
- Lenain Jean-Philippe
- Leonard Kayla
- Leone Francesco
- Leszczyńska Agnieszka
- Leuschner Fabian
- Levy Christelle
- Li Yijia
- Lincetto Massimiliano
- Lindfors Elina
- Linhoff Lena
- Liu Qinrui
- Liubarska Maria
- Lohfink Elisa
- Lohse Thomas
- Lombardi Saverio
- Longo Francesco
- Lopez-Coto Ruben
- Loporchio Serena
- Lozano Mariscal Cristian Jesus
- López-Moya Marcos
- López-Oramas Alicia
- Lu Lu
- Luashvili Anna
- Lucarelli Francesco
- Ludwig Andrew
- Luszczak William
- Lypova Iryna
- Lyu Yang
- Ma Wing Yan
- Machado de Oliveira Fraga Bernardo
- Mackey Jonathan
- Madsen James
- Maggio Camilla
- Mahn Kendall
- Majumdar Jhilik
- Majumdar Pratik
- MAKARIEV Martin
- Makino Yuya
- Mallamaci Manuela
- Malyshev Denys
- Malyshev Dmitry
- Mancina Sarah
- Maneva Galina
- Manganaro Marina
- Mannheim Karl
- Marandon Vincent
- Maraschi Laura
- Marchegiani Paolo
- Marcowith Alexandre
- Mares Arnaud
- Mariotti Mosè
- Maris Ioana Codrina
- Martinez Manel
- Martí-Devesa Guillem
- Maruyama Reina H.
- Marx Ramin
- Mase K.
- Maurin Gilles
- Mazin Daniel
- McElroy Thomas
- McNally Frank
- Mead James Vincent
- Meagher K.
- Medina Andres
- Meier Maximilian
- Meighen-Berger Stephan
- Meintjes Pieter
- Menchiari Stefano
- Mender Simone
- Meyer Manuel
- Micallef Jessie
- Miceli Davide
- Mićanović Saša
- Miener Tjark
- Miranda Jose Miguel
- Mirzoyan Razmik
- Mitchell Alison
- Mockler Daniela
- Moderski Rafal
- Mohrmann Lars
- Molina Edgar
- Montanari Alessandro
- Montaruli Teresa
- Moore Chris
- Moore Roger
- Moralejo Abelardo
- Morcuende Daniel
- Moreno Victoria
- Moretti Elena
- Morris Paul
- Morse R.
- Moulai Marjon
- Moulin Emmanuel
- Muller Jacques
- Murach Thomas
- Naab Richard
- Nagai Ryo
- Nakamori Takeshi
- Nakashima Kaori
- Naumann Uwe
- Naurois (de) Mathieu
- Nava Lara
- Nayerhoda Amid
- Necker Jannis
- Neise Dominik
- Neustroev Vitaly
- Nguyen Le Viet
- Niederhausen Hans
- Niemiec Jacek
- Nigro Cosimo
- Nilsson Kari
- Nisa Mehr
- Nishijima Kyoshi
- Noda Koji
- Noel Angel
- Noethe Maximilian
- Nowicki Sarah
- Nozaki Seiya
- Nygren Dave
- O'Brien Paul
- O'Sullivan Erin
- Oberholzer Laenita Lorraine
- Obertacke Pollmann Anna
- Oehler Marie
- Ohm Stefan
- Ohtani Yoshiki
- Oka Tomohiko
- Olivas A.
- Olivera-Nieto Laura
- Ona-Wilhelmi (de) Emma
- Ostrowski Michal
- Otero-Santos Jorge
- Paiano Simona
- Palatiello Michele
- Pandya Hershal
- Paneque David
- Pankova Daria
- Panny Sebastian
- Panter Michael
- Paoletti Riccardo
- Paravac Aleksander
- Paredes Josep M.
- Park Nahee
- Parker Grant
- Parsons Dan
- Paudel Ek Narayan
- Paul Larissa
- Pavletić Lovro
- Peñil Pablo
- Perez de los Heros Carlos
- Peron Giada
- Persic Massimo
- Peters Lilly
- Philippen Saskia
- Pieloth Damian
- Pieper Sarah
- Pihet Marine
- Pita Santiago
- Pittermann Martin
- Pizzuto A.
- Plum M.
- Poireau Vincent
- Popovych Yuiry
- Porcelli Alessio
- Prada Moroni Pier Giorgio
- Prado Rodriguez Maria
- Prandini Elisa
- Price P. Buford
- Pries Brandom
- Priyadarshi Chaitanya
- Prokhorov Dmitry
- Prokoph Heike
- Przybylski Gerald
- PUEHLHOFER Gerd
- Puljak Ivica
- Punch Michael
- Quirrenbach Andreas
- Raab Christoph
- Raissi Amirreza
- Rameez Mohamed
- Rawlins K.
- Rea Immacolata Carmen
- Rehman Abdul
- Reichherzer Patrick
- Reimann René
- Reimer Anita
- Reimer Olaf
- Remy Quentin
- Renaud Matthieu
- Renzi Giovanni
- Resconi Elisa
- Reusch Simeon
- Reville Brian
- Rhode Wolfgang
- Ribó Marc
- Richman Mike
- Rico Javier
- Riedel Benedikt
- Rieger Frank
- Righi Chiara
- Roberts Ella
- Robertson Sally
- Roellinghoff Gerrit
- Romoli Carlo
- Rongen Martin
- Rott Carsten
- Rowell Gavin
- Rudak Bronislaw
- Rueda Ricarte Hector
- Rugliancich Andrea
- Ruhe Tim
- Ruiz Velasco Edna
- Ryckbosch Dirk
- Rysewyk Cantu Devyn
- Safa Ibrahim
- Saffer Julian
- Sahakian Vardan
- Sahakyan Narek
- Sailer Simon
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- VAZQUEZ ACOSTA Monica
- Veh Johannes
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- VERGUILOV Vassil
- Verpoest Stef
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- Völk Heinrich J.
- Vraeghe Matthias
- Wagner Stefan
- Walck C.
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- Watson Timothyblake
- Weaver Chris
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- Weindl Andreas
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- Wendt Chris
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- Weyrauch Mark
- White Richard
- Whitehorn Nathan
- Wiebusch C. H.
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- Will Martin
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- Wolf Martin
- Wong Yu Wun
- Woschnagg Kurt
- Wrede Gerrit
- Wulff Johan
- Wunderlich Carolin
- Xu Xianwu
- Xu Yiqian
- Yamamoto Tokonatsu
- Yanez Juan Pablo
- Yassin Hend Mahmoud
- Yoshida S.
- Yu Shiqi
- Yuan Tianlu
- Yusafzai Anke
- Zacharias Michael
- Zanin Roberta
- Zargaryan Davit
- Zarić Darko
- Zdziarski Andrzej
- Zech Andreas
- Zhang Zelong
- Zhu Sylvia
- Zmija Andreas
- Zouari Samuel
- Żywucka Natalia
- Publication venue
- Publication date
- 01/01/2022
- Field of study
The realtime follow-up of neutrino events is a promising approach to search for astrophysical neutrino sources. It has so far provided compelling evidence for a neutrino point source: the flaring gamma-ray blazar TXS 0506+056 observed in coincidence with the high-energy neutrino IceCube-170922A detected by IceCube. The detection of very-high-energy gamma rays (VHE, E>100GeV
E
>
100
G
e
V
) from this source helped establish the coincidence and constrained the modeling of the blazar emission at the time of the IceCube event. The four major imaging atmospheric Cherenkov telescope arrays (IACTs) - FACT, H.E.S.S., MAGIC, and VERITAS - operate an active follow-up program of target-of-opportunity observations of neutrino alerts sent by IceCube. This program has two main components. One are the observations of known gamma-ray sources around which a cluster of candidate neutrino events has been identified by IceCube (Gamma-ray Follow-Up, GFU). Second one is the follow-up of single high-energy neutrino candidate events of potential astrophysical origin such as IceCube-170922A. GFU has been recently upgraded by IceCube in collaboration with the IACT groups. We present here recent results from the IACT follow-up programs of IceCube neutrino alerts and a description of the upgraded IceCube GFU system
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
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- Al basos Iyad
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- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
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- Albahnasawi Moath A.
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- Ali SANI Samuel
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- Aljohmani Lylas
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- Alkhatib Ala'a Aldeen
- Alkhatib Haya
- Alkhatib Mo'min
- Allen Ingabire J.C.
- Almasri Murad
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- Almeida Filipe
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- Alvarez Rivera Alvaro Eduardo
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- Nevado García Cristina
- Neves Christian
- Neves Jessica
- Newall Nicola
- Newman Elliot
- Nezerwa Yves
- Ng We Yong Yuki Julius
- Ng Elaine Hui Been
- Ng James Chean Khun
- Ng Li-Yen
- Ng Michael
- Ng Nathan
- Ngai Carlin
- Ngotho Omar
- Nicholson Gary
- Nico Albano Miguel
- Nigard Linda
- Nigo Samuel Lemery
- Nikberg Maziar
- Nikoloudis Nikolaos
- Nina Helidon
- Nino- Torres Laura
- Niquen Jimenez Maria Milagros
- Nita Gabriela Elisa
- Nogueira Sixto Manuel
- Nogueira Oriana
- Nomura Andrea
- Noor Fazlin
- Norcic Gregor
- Norman Lisa
- Nour Ibrahim
- Novoa Armando
- Nozal Beatriz
- Nsengimana Vizir J.P.
- Nsengiyumva Carlos
- Ntaoulas Sotirios
- Ntirenganya Faustin
- Nubani Yanal
- Nugrahadi Nadia Rahmadiani
- Nunoo-Mensah Joseph
- Nutautiene Vitalija
- Nwachukwu Callistus
- Nwokocha Samuel
- Nwolu Favour
- Nyangoh Timoh Krystel
- O'Connor Donal B
- O'Neill Maeve
- O'Shea Margaret
- Obaid Mohammed
- Obery Gareth
- Occhionorelli Savino
- Oganezov Giorgi
- Ogundoyin Olakayode
- Ojewola Rufus Wale
- Okalany Noella
- Olajide Thomas Olagboyega
- Olaogun Julius
- Olasehinde Olalekan
- Olazo Espejo Dennet Arturo
- Oliveira Ana Carolina
- Oliveira Joana
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- Omar Cinderella
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- Omar Samah
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- Otero-Diez Jorge L.
- Othman Gehad
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- Owusu senior Atta
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- Paramzin Fedor
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- Pegba-Otemolu Ibifunke
- Peixoto Rita
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- Pellegrino Luca
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- Peltrini Roberto
- Pengermä Pasi
- Pepe Vincenzo
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- Perdomo Perez Mauro Andres
- Perduca Pietro
- Pereira Jorge
- Pereira José Carlos
- Pereira Mário
- Perepelytsia Kateryna
- Perera Omattage Mahasha
- Perez Rivera Carlos J-
- Perivoliotis Konstantinos
- Peros Georgios
- Perrone Fabrizio
- Perrone Kenneth
- Pesenti Giovanni
- Peterer Lorenz
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- Razafimanjato Narindra Njarasoa Mihaja
- Realis Luc Alberto
- Recinos Gustavo
- Reda Loaloa Mohamed
- Refaat Ahmed
- Refky Basel
- Rega Daniela
- Reia Marta
- Reinisch Katharina Beate
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- Reyes Afonso Eduardo
- Riad Aya
- Ribeiro da Silva Bruno
- Ribeiro Hugo
- Ribeiro João
- Richards Simon
- Richards Sophie
- Ridgway Paul
- Ridley William
- Ripollés-Melchor Javier
- Rivera Lara Verónica
- Rivero Déniz Joaquín
- Rizzo Giovanna
- Robertson Harry
- Rocha Melo Miguel
- Rocha Ana
- Rodicio Miravalles Jose Luis
- Rodrigues Ferreira Joana
- Rodriguez Fraga Pastora
- Rodriguez Gonzalez Agustin
- Rodriguez-Aguirre Montserrat
- Rodriguez-Lopez Mario
- Rodríguez Angeles Yamile
- Rodríguez Cantera Gabriela
- Rodríguez Fernández Laura
- Rojo López Jose Alberto
- Roldón Golet Marta
- Romano Joana
- Romano Manuela
- Romanova Ekaterina
- Romanukha Kateryna
- Romero-Garza Hector Hugo
- Rompou Vaia-Aliki
- Rooney Siobhan
- Rosado Daniela
- Rose Anna
- Rosko Damir
- Roslani April Camilla
- Rosser Kenrick
- Roszkowski Rafal
- Rotolo Giulia
- Rottier Simone
- Roum Radwa
- Ruano Poblador Alejandro
- Rubinkiewicz Mateusz
- Rubio-Perez Ines
- Rueda Nataly
- Rufo Crespo Erika
- Rugendyke Anya
- Ruiz Soriano María
- Ruiz-Tovar Jaime
- Rupani Shamil
- Russo Alfio Alessandro
- Rutherford Duncan
- Rutkovskii Valeryan
- Rutkovskii Vasilii
- Rybakov Evgeny
- Rye Dupinderjit
- Rzepa Anna
- S Vinay
- Sa'deh Mohammad
- Saad Ahmad
- Saad Mahmoud
- Saadeh Rana
- Sabry Ahmed
- Sacco Michele
- Sacdalan Marie Dione
- Saddouh Enas
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- Safadi Khalil
- Safy Amina
- Sagnotta Andrea
- Sahbaz Nuri Alper
- Sahin Can
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- Saifutdinova Karina
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- Salama Ebram
- Salameh Mohammad Hasan
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- Sale Danjuma
- Saleem Abdulaziz
- Saleem Omair
- Saleh Bakeer
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- Samison Luc Hervé
- Sammarco Giuseppe
- Sammour Tarik
- Sammut Kim
- Sampaio da Nóvoa Gomes Miguel Inês Isabel
- Sampaio Soares António
- Sampietro Gianluca Matteo
- Samra Tahani
- Samy Fatma
- Sanchez Bartra Nestor Alberto
- Sanchez Andres
- Sanchez-Santos Raquel
- Santandrea Letizia
- Santarrufina Martinez Sandra
- Santos Bezerra Tainá
- Santos Inês
- Santos Vanessa
- Sapallanay Ojeda Olenka
- Sapienza Paolo
- Saqqa Bader
- Sara Samer
- Sarfraz Muzna
- Sarici Inanc Samil
- Sarrami Mahsa
- Sarwar Muhammad
- Sasia Diego
- Savenkov Dmytro
- Savli Evrim
- Sawiee Adnan
- Sayed Mohamed Marwa
- Sayed Ahmed
- Sayed Taqwa
- Sayyed Raza
- Scala Dario
- Scaramuzzo Rosa
- Schizas Dimitrios
- Schrire Timothy
- Sciaudone Guido
- Sciuto Pablo
- Seak Jonathan Chen Ken
- Sebastián Tomás Juan Carlos
- Seeger Nico
- Segovia Lohse Helmut Alfredo
- Sehrish Rahmat
- Seire Indrek
- Sel EDA KÜBRA
- Seldon Yeshey
- Sellars Kate
- Selvaggi Francesco
- Selvaggi Lucio
- Semeda Nourhan
- Semiz Anil
- Sena Giuseppe
- Senanayake Kithsiri Janakantha
- Sequeira Sangita
- Sequeiros Diego
- Sera Ahmed shible
- Sera Marwa
- Settipalli Krishna Pranathi
- Sevim Sule
- Seyoji Mohammed
- Sgrò Alessandro
- Shaeeb Zuhour
- Shah Max
- Shah Reena
- Shaheen Ahmad
- Shaheen Nureddin
- Shahien Fatma
- Shahzad Noman
- Shaker Nancy
- Shakhmatov Dmitry
- Shalaby Hind I.
- Shalaby Mostafa
- Sharif Randa
- Sharma Parivrudh
- Shaw Catherine A
- Shaw Mike
- Shawqi Muhammad
- Shazly Omar
- Shebani Abdulhalim
- Shehab-Eldeen Noura
- Shehada Mohammed
- Shehada Tarneem
- Shenoy Aneesh
- Sheriff Mohammed
- Sheshe Abdurrahman Abba
- Shihada Karam
- Shivashankar Chikkanayakanahalli Santhosh
- Shiwani Haaris
- Shkokani Sundus
- Sholadoye Tunde T.
- Sholi Tasnim
- Shong Sheng Tan
- Shrikhande Shailesh
- Shu Yip Sebastian
- Shushval Mikhail
- Siaw Jia yng
- Sibilla Maria Grazia
- Sierra Sebastian
- Sihotang Retta Catherina
- Silva de Sousa Fabiana
- Silva Anaisa
- Silva Marta
- Silva Sofia
- Silva-Vaz Pedro
- Simcikas Dainius
- Simel Ian
- Simic Andrea
- Simuchimba Elliot
- Simões Joana
- Sinead Mackay
- Sinha Aanjaneya
- Sinibaldi Giovanni
- Siow Jin Phuah
- Siryi Stanislav
- Siso Raber Christian
- Skoczylas Tomasz
- Skroubis George
- Slavchev Mihail
- Slepavicius Algirdas
- Slim Skander
- Sluiter Nina
- Smart Neil
- Smith Scott
- Smith Stephen
- Smolskas Edgaras
- Sobhy Mohamed
- Sokolov Manol
- Solano-Genesta Manuel
- Solar-Garcia Lorena
- Soliman Mostafa
- Soliman Nourhan Akram
- Solinas Luigi
- Sollazzo Viviana
- Sorrentino Luca
- Soula Enas
- Soulabaille Lucie
- Sousa Diogo
- Sowemimo Olamiposi
- Speake Doug
- Spence Richard
- Spiezio Giovanni
- Spinelli Antonino
- Spoletini Domenico
- Sridhar Shruthi
- Srivastava Prakhar
- Sroor Fathy
- Srour Abedelrahman
- St-Amour Pénélope
- Stakelum Aine
- Stakyte Migle
- Stanek Maciej
- Stanley Mwenda Aruyaru
- Starr Robert
- Steenkamp Christina Johanna
- Stellingwerf Merel Elisabeth
- Stevenson Annie
- Stewart Caitlin
- Stewart Peter
- Steynfaardt Leandi
- Stift Anton
- Stock Simon
- Stoica Bogdan
- Stoots Simone
- Stoyanov Vladislav
- Suarez Antonio
- Subocius Andrejus
- Subramaniam Suren
- Sudeikyte Monika
- Sulaiman Syariz Ezuan
- Suleihat Ahmad
- Suleiman Ibrahim
- Sulpice Laurent
- Sultan Abdullah
- Sultan Ahmed
- Summerour Virginia
- Sund Malin
- Suradi Haya H.
- Suresh Gayathri
- Suresh Rishi
- Sushkov Oleg
- Suárez Sánchez Aida
- Svagzdys Saulius
- Syed Aamir Ali
- Syed Bilal
- Syllaios Athanasios
- Sylvester Kimutai
- Syminas Vilius
- Szabadhegyi Gabor
- Szabó Réka
- Szyszka Bartosz
- Sánchez Suárez Ramses
- Sánchez-García Jorge
- Sánchez-Guillén Luis
- Søreide Kjetil
- Tababa Osama
- Tabiri Stephen
- Tagliabue Fulvio
- Taglietti Lucio
- Taha Ehab
- Taha Esraa
- Tahboub Haya
- Tahir Abd al-Rahman
- Taiwo Agboola
- Taiwo Ogechukwu
- Takala Sini
- Talal El-Abur Issa
- Talavera Cherry
- Tamelis Algimantas
- Tamini Nicolò
- Tamosiunas Albinas
- Tampaki Ekaterini Christina
- Tampo Mayou Martin
- Tan Ern Hwei Jeremy
- Tan Daniel
- Tan Gerald Jack Soon
- Tan Hao Han
- Tan Ryan Renxin
- Tan Tanna
- Tang Yita
- Tanis Pieter
- Tankel James
- Tapia Marin Walezka
- Tapkire Ritesh
- Taranu Viorel
- Tarek Ahmed
- Taré Filipa
- Tashkandi Hanaa
- Tashkandi Wail
- Tatar Ozan Can
- Tavlas Panagiotis
- Tawalbeh Ra'fat
- Tawalbeh Tamara
- Tayar Serkan
- Teasdale Ella
- Teh Jen
- Tejeda Garrido Jorge Carlos Guillermo
- Tennakoon Athula
- Tepe Mustafa Deniz
- Teppo Sandra
- Ter Alvin Zubin
- Teras Jyri
- Tereshchenko Maksym
- Tew Yong Yong
- Thakkar Purvi
- Thalgaspitiya Sujeewa Priyantha Bandara
- Tharanath Kavya
- Tharwat Hoda
- Theodoropoulos Charalampos
- Theodorou Dimitrios
- Theodosopoulos Theodosios
- Theofanis George
- Thomas Hannah
- Thomas Jimmy Scott
- Thomas-Jones Iolo
- Thompson Amari
- Thompson Joanna
- Thorell Anders
- Tin Moe Moe
- Tinton Nicolas
- Tiong Ing Ching
- Titan Ashley
- Tlhomelang Omphile
- Todorov George
- Tojal André
- Tol Isabel
- Tomas Kadir
- Tomazic Ales
- Tomé Miguel
- Tondo Matteo
- Tonini Valeria
- Torre Ana
- Torrent Jansà Laia
- Toscano Pacheco Andrea
- Toussaint Arnaud
- Townson Adam
- Trabulsi Nora
- Trenba Sarah
- Triantafyllou Tania
- Tribedi Thomas
- Troche Pesqueira Noemí
- Troche José Manuel
- Troilo Francesca
- Trompetto Mario
- Tropeano Francesca Paola
- Trostchansky Ivan
- Truan Nuria
- Trugeda-Carrera Maria Soledad
- Trujillo Díaz Jeancarlos
- Trullenque Juan Ramon
- Truncíková Vendula
- Truong Anthony
- Truszkiewicz Katarzyna
- Tryliskyy Yegor
- Tsandiraki Justin
- Tsimpoukelis Antonios
- Tucker Sally
- Tulley Joshua
- Turati Luca
- Turri Giulia
- Turunen Antti
- Turunen Arto
- Tutino Roberta
- Tuynman Jurriaan
- Tyselskiy Volodimir
- Tzovaras George
- Tüfek Ozan yavuz
- Türkyilmaz Serdar
- Ubartas Nerijus
- Ugoletti Lara
- Ugolini Giampaolo
- Ulusahin Mehmet
- Umenze Franklin
- Umoke Ifeanyi
- Underwood Charlotte
- Unger Lukas Walter
- Urbieta Aitor
- Urbonas Tomas
- Uribe Valencia Andres
- Usai Antonella
- Usta Arif
- Utrilla Fornals Alejandra
- Uwakunda Carine
- Uy Gemma Leonora
- Uysal Muhammed
- V Sushmita
- Valente da Costa Ana
- van Berge Henegouwen Mark I.
- van Dalen Anne Sophie
- Van Der Merwe Lisa Hannah
- van Geloven Aaw
- Van hentenryck Marie
- van Praag Elise Maria
- van Schilt Kaz
- Van Straten Stephanie
- van Wyngaard Tirsa
- Vanagas Tomas
- Vanella Serafino
- Vanoye Elva Gabriela
- Vardanyan Armen
- Varghese Shriya
- Varol Ecenur
- Vaska Ashish I
- Vaughan-Shaw Peter G
- Vaysse Charlotte
- Vazquez Fernandez Andrea
- Veale Kelly
- Vega Victor
- Veiga Diogo
- Velez Cristina
- Venskutonis Donatas
- Venturelli Paolina
- Verdaguer Tremolosa Mireia
- Vergara María
- Vergara-Fernandez Omar
- Vervoort Dominique
- Vescio Giuseppina
- Viacheslav Nezamai
- Vicario Bravo Marina
- Vidal Meza Maitza Rosario
- Vieira Barros Aldo
- Vieira Caroço Teresa
- Vieira Ana
- Vieira Bárbara
- Vigorita Vincenzo
- Vijaykumar D.K.
- Vijeyan Harinthiran
- Viljoen Francois
- Villalobos Santiago
- Vincenti Leonardo
- Violi Paola
- Virbickaite Egle
- Vlek Stijn
- Volovetskyi Anton
- Wafaa Mariam
- Wafqui fatima Zahraa
- Wagner Gabriela
- Wakkaf Habib
- Waledziak Maciej
- Wall Ellen
- Walsh Una
- Walter Catherine
- Wan Khazim Wan Khamizar
- Wan Muhmad Wan Farahiyah
- Wandschneider Wiebke
- Wanniang Cliff
- Waqar Shahzad Hussain
- Warden Claire
- Warren Craig Russell
- Warren Oliver
- Warwick Andrea
- Warwicker Sean
- Wason Deepender
- Waterman Ade
- Watts Daniel
- Weiser Thomas G
- Welch Matthew
- Wellington Jack
- Wells Anna
- Wells Cameron
- West Malcolm
- Westerduin Emma
- Weyl Ariane
- Whisker Lisa
- Whitaker John
- White Rebecca
- Wiberg Rebecca
- Widmer Lukas Werner
- Wierdak Mateusz
- Wijekoon Arachchilage Nimeshi
- Willemin Melissa
- Williams Christopher Yee Khang
- Wills Vanessa
- Wilson Karim
- Wilson Michael
- Wimmer Kerstin
- Wineberg Devorah
- Winiarski Marek
- Winoto Hadi
- Winter Beatty Jasmine
- Winter Des
- Wisal Maham
- Wisselink Daan
- Wogensen Fredrik
- Wondoh Paul M.
- Wong Florence
- Wong Hsu Ven
- Wong Jane J
- Wong Jeremy
- Wong Lai Fen
- Wong Michael Pak-Kai
- Wong Sui-Weng
- Wong Tsz Lun Ernest
- Wood Lauren
- Woon-Shoo-Tong Xiao-Ming Sarah
- Wren Sherry
- Wuraola Funmilola
- Xanthopoulou Georgia
- Yabut Kenneth
- Yacoub Aseel
- Yaghi Nadine
- Yaghi Yasmine
- Yahia Mohamed Ali Mohamed
- Yakushkina Al'ona
- Yalçinkaya Ali
- Yang P Zichu
- Yanikoglu Erkan
- Yanni Fady
- Yates Charlotte
- Ye Geoffrey
- Yeen Chin Leow
- Yemez Kürsat
- Yenidünya Nilüfer
- Yenli Edwin
- Yeo Jeremy
- Yeoh Andrea
- Yesilsancak Merve
- Yildirim Reyyan
- Yildiz Alp
- Yilmaz Duygu
- Yip Ching Wan
- Ylatoma Díaz Edgar Alcides
- Yong Shun Qi
- Yoong Andrel
- Yorke Joseph
- Yotsov Tsanko
- You Lucia
- Younes Eman
- Younes Maha
- Yousry Basant
- Yozgatli Tahir Koray
- Yu Kristin
- Yue Sum Yu Pansy
- Yunes Asmaa
- Yusuf Baasil
- Yüksel Osman
- Zabiyaka Mikhail
- Zachariah Sanoop Koshy
- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Šatkauskas Mindaugas
- Škimelyte Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 30/01/2021
- Field of study
© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
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- McManus Brendan
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- Wondoh Paul M.
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- Yanikoğlu Erkan
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- Ye Geoffrey
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- Yenli Edwin
- Yeo Jeremy
- Yeoh Andrea
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- Yeşilsancak Merve
- Yildirim Reyyan
- Yildiz Alp
- Yilmaz Duygu
- Yip Ching Wan
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- Yong Shun Qi
- Yoong Andrel
- Yorke Joseph
- Yotsov Tsanko
- You Lucia
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- Yüksel Osman
- Zabiyaka Mikhail
- Zachariah Sanoop Koshy
- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Čepuliené Daiva
- Şahin Can
- Šatkauskas Mindaugas
- Škimelytè Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/2022
- Field of study
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research