Ground-layer wavefront reconstruction from multiple natural guide stars

Observational tests of ground layer wavefront recovery have been made in open loop using a constellation of four natural guide stars at the 1.55 m Kuiper telescope in Arizona. Such tests explore the effectiveness of wide-field seeing improvement by correction of low-lying atmospheric turbulence with ground-layer adaptive optics (GLAO). The wavefronts from the four stars were measured simultaneously on a Shack-Hartmann wavefront sensor (WFS). The WFS placed a 5 x 5 array of square subapertures across the pupil of the telescope, allowing for wavefront reconstruction up to the fifth radial Zernike order. We find that the wavefront aberration in each star can be roughly halved by subtracting the average of the wavefronts from the other three stars. Wavefront correction on this basis leads to a reduction in width of the seeing-limited stellar image by up to a factor of 3, with image sharpening effective from the visible to near infrared wavelengths over a field of at least 2 arc minutes. We conclude that GLAO correction will be a valuable tool that can increase resolution and spectrographic throughput across a broad range of seeing-limited observations.Comment: 25 pages, 8 figures, to be published in Astrophys.

On-sky wide field adaptive optics correction using multiple laser guide stars at the MMT

We describe results from the first astronomical adaptive optics system to use multiple laser guide stars, located at the 6.5-m MMT telescope in Arizona. Its initial operational mode, ground-layer adaptive optics (GLAO), provides uniform stellar wavefront correction within the 2 arc minute diameter laser beacon constellation, reducing the stellar image widths by as much as 53%, from 0.70 to 0.33 arc seconds at lambda = 2.14 microns. GLAO is achieved by applying a correction to the telescope's adaptive secondary mirror that is an average of wavefront measurements from five laser beacons supplemented with image motion from a faint stellar source. Optimization of the adaptive optics system in subsequent commissioning runs will further improve correction performance where it is predicted to deliver 0.1 to 0.2 arc second resolution in the near-infrared during a majority of seeing conditions.Comment: 13 pages, 1 table, 7 figures. Accepted for publication in Astrophysical Journal. Expected March 200

Development of outbred CD1 mouse colonies with distinct standardized gut microbiota profiles for use in complex microbiota targeted studies.

Studies indicate that the gut microbiota (GM) can significantly influence both local and systemic host physiologic processes. With rising concern for optimization of experimental reproducibility and translatability, it is essential to consider the GM in study design. However, GM profiles can vary between rodent producers making consistency between models challenging. To circumvent this, we developed outbred CD1 mouse colonies with stable, complex GM profiles that can be used as donors for a variety of GM transfer techniques including rederivation, co-housing, cross-foster, and fecal microbiota transfer (FMT). CD1 embryos were surgically transferred into CD1 or C57BL/6 surrogate dams that varied by GM composition and complexity to establish four separate mouse colonies harboring GM profiles representative of contemporary mouse producers. Using targeted 16S rRNA amplicon sequencing, subsequent female offspring were found to have similar GM profiles to surrogate dams. Furthermore, breeding colonies of CD1 mice with distinct GM profiles were maintained for nine generations, demonstrating GM stability within these colonies. To confirm GM stability, we shipped cohorts of these four colonies to collaborating institutions and found no significant variation in GM composition. These mice are an invaluable experimental resource that can be used to investigate GM effects on mouse model phenotype

Modeling of pulsed laser guide stars for the Thirty Meter Telescope project

The Thirty Meter Telescope (TMT) has been designed to include an adaptive optics system and associated laser guide star (LGS) facility to correct for the image distortion due to Earth's atmospheric turbulence and achieve diffraction-limited imaging. We have calculated the response of mesospheric sodium atoms to a pulsed laser that has been proposed for use in the LGS facility, including modeling of the atomic physics, the light-atom interactions, and the effect of the geomagnetic field and atomic collisions. This particular pulsed laser format is shown to provide comparable photon return to a continuous-wave (cw) laser of the same average power; both the cw and pulsed lasers have the potential to satisfy the TMT design requirements for photon return flux.Comment: 16 pages, 20 figure

Evaluation of the Northern Territory Library's Libraries and Knowledge Centres Model

Evaluation of the Northern Territory Library's model for Libraries and Knowledge Centres in Indigenous communities

Commissioning the MMT ground-layer and laser tomography adaptive optics systems

A multi-laser adaptive optics system, at the 6.5 m MMT telescope, has been undergoing commissioning in preparation for wide-field, partially corrected as well as narrow-field, diffraction limited science observations in the thermal and near infrared. After several delays due to bad weather, we have successfully closed the full high order ground-layer adaptive optics (GLAO) control loop for the first time in February 2008 using five Rayleigh laser guide stars and a single tilt star. Characterization and automated correction of static aberrations such as non-common path errors were addressed in May 2008. Calibration measurements in preparation for laser tomography adaptive optics (LTAO) operation are planned for the fall of 2008 along with the start of shared-risk GLAO science observations. We present the results of GLAO observations with the PISCES imager, a 1 - 2.5 µm camera with a field of view of 110 arc seconds. The status of the remaining GLAO commissioning work is also reviewed. Finally, we present plans for commissioning work to implement the LTAO operating mode of the system

Vertical stiffness asymmetries during drop jumping are related to ankle stiffness asymmetries

Asymmetry in vertical stiffness has been associated with increased injury incidence and impaired performance. The determinants of vertical stiffness asymmetry have not been previously investigated. Eighteen healthy males performed three unilateral drop jumps during which vertical stiffness and joint stiffness of the ankle and knee were calculated. Reactive strength index was also determined during the jumps using the ratio of flight time to ground contact time. ‘Moderate’ differences in vertical stiffness (t17 = 5.49; P < 0.001), ‘small’ differences in centre of mass displacement (t17 = -2.19; P = 0.043) and ‘trivial’ differences in ankle stiffness (t17 = 2.68; P = 0.016) were observed between stiff and compliant limbs. A model including ankle stiffness and reactive strength index symmetry angles explained 79% of the variance in vertical stiffness asymmetry (R2 = 0.79; P < 0.001). None of the symmetry angles were correlated to jump height or reactive strength index. Results suggest that asymmetries in ankle stiffness may play an important role in modulating vertical stiffness asymmetry in recreationally trained males

Holding and restraining children for clinical procedures within an acute care setting: an ethical consideration of the evidence

This critical reflection on the ethical concerns of current practice is underpinned by a systematic synthesis of current evidence focusing on why and how children are held or restrained for clinical procedures within acute care and the experiences of those present when a child is held against their wishes. Empirical evidence from a range of clinical settings internationally demonstrates that frequently children are held for procedures to be completed; younger children and those requiring procedures perceived as urgent are more likely to be held. Parents and health professionals express how holding children for procedures can cause feelings of moral distress expressed as uncertainty, guilt and upset and that this act breaches the trusting and protective relationship established with children. Despite this, children’s rights and alternatives to holding are not always respected or explored. Children’s experiences and perceptions are absent from current literature. Children and young people have a moral right to have their voice and protests heard and respected and for these to inform judgements of their best interests and the actions of health professionals. Without robust evidence, debate and recognition that children are frequently held against their wishes in clinical practice for procedures which may not be urgent, children’s rights will continue to be compromised

Eu-Social Science: The Role of Internet Social Networks in the Collection of Bee Biodiversity Data

Background\ud \ud Monitoring change in species diversity, community composition and phenology is vital to assess the impacts of anthropogenic activity and natural change. However, monitoring by trained scientists is time consuming and expensive.\ud \ud Methodology/Principal Findings\ud \ud Using social networks, we assess whether it is possible to obtain accurate data on bee distribution across the UK from photographic records submitted by untrained members of the public, and if these data are in sufficient quantity for ecological studies. We used Flickr and Facebook as social networks and Flickr for the storage of photographs and associated data on date, time and location linked to them. Within six weeks, the number of pictures uploaded to the Flickr BeeID group exceeded 200. Geographic coverage was excellent; the distribution of photographs covered most of the British Isles, from the south coast of England to the Highlands of Scotland. However, only 59% of photographs were properly uploaded according to instructions, with vital information such as ‘tags’ or location information missing from the remainder. Nevertheless, this incorporation of information on location of photographs was much higher than general usage on Flickr (∼13%), indicating the need for dedicated projects to collect spatial ecological data. Furthermore, we found identification of bees is not possible from all photographs, especially those excluding lower abdomen detail. This suggests that giving details regarding specific anatomical features to include on photographs would be useful to maximise success.\ud \ud Conclusions/Significance\ud \ud The study demonstrates the power of social network sites to generate public interest in a project and details the advantages of using a group within an existing popular social network site over a traditional (specifically-designed) web-based or paper-based submission process. Some advantages include the ability to network with other individuals or groups with similar interests, and thus increasing the size of the dataset and participation in the project

Sensations of skin infestation linked to abnormal frontolimbic brain reactivity and differences in self-representation

Some patients experience skin sensations of infestation and contamination that are elusive to proximate dermatological explanation. We undertook a functional magnetic resonance imaging study of the brain to demonstrate, for the first time, that central processing of infestation-relevant stimuli is altered in patients with such abnormal skin sensations. We show differences in neural activity within amygdala, insula, middle temporal lobe and frontal cortices. Patients also demonstrated altered measures of self-representation, with poorer sensitivity to internal bodily (interoceptive) signals and greater susceptibility to take on an illusion of body ownership: the rubber hand illusion. Together, these findings highlight a potential model for the maintenance of abnormal skin sensations, encompassing heightened threat processing within amygdala, increased salience of skin representations within insula and compromised prefrontal capacity for self-regulation and appraisal