Should I fall and fail to rise

Early in the morning, before the wind takes up its broom, you can see where claws have carved cuneiform runes into the curve and crest of the dune

The Riddles of Mazeppa; or, More Questions than Answers:Watermarks and cohabitations, April 1817-September 1818

Byron's Mazeppa is an unusual case in his writing career. He was generally a quick writer, but this poem - an important link between his earlier melodramatic tales and his later comic ones -was started in April 1817 and completed only in September 1818, nearly eighteen months later. This essay uses various forms of evidence, in particular literary allusion and the various paper stocks on which the poem was drafted, to suggest when and where the poem was 'broken off' before being finally completed. It also considers in the poem in the light of other works written during the period (The Lament of Tasso, Manfred, Childe Harold IV, Beppo, and Don Juan) before considering its overall theme in contrast to Voltaire's History of Charles XII

Surgical technique for arthroscopic onlay suprapectoral biceps tenodesis with an all-suture anchor.

The long head of the biceps is a frequent pain generator in the shoulder. Tendinopathy of the long head of the biceps may be treated with biceps tenodesis. There has been great debate about the optimal technique for biceps tenodesis, without a clear distinction between different techniques. Biceps tenodesis fixation may include interference fixation, suspensory fixation, all-suture anchors, and soft tissue fixation. In this technical note, we describe an all-arthroscopic onlay suprapectoral biceps tenodesis with an all-suture anchor

The red patas monkey (Erythrocebus paras): An analysis of pathological changes and organ/body weight data in laboratory animals in a 12 year period

The histopathology and body and organ weights have been evaluated for 76 adult red patas monkeys used as controls in routine short term toxicity studies.Body and organ weights varied considerably, males weighting 2.45—7.7 kg and females 2.65—4.80 kg. Absolute organ weights did not exhibit a clear graphical relationship to body weight, although brain weight did show an exponential relationship when its weight relative to body weight was plotted against body weight.Neoplastic changes were not seen in any male or female animal. Common lesions included sialodacroadenitis, sub-acute thyroiditis, chronic respiratory disease, interstitial nephritis and cystitis. Pulmonary and intestinal nematode infections were present in ten animals. It is concluded that the range of lesions identified resemble those present in many other species of laboratory animal maintained under conventional laboratory conditlons

Imaging-Based Prevalence of Superior Labral Anterior-Posterior Tears Significantly Increases in the Aging Shoulder.

BackgroundSuperior labral anterior-posterior (SLAP) tears can be associated with pain and shoulder dysfunction. Relatively little is known about the age-related prevalence of SLAP tears.PurposeTo investigate the age-related prevalence of imaging-diagnosed SLAP tears in a heterogeneous grouping of shoulder conditions in a large cohort at a single institution with multiple blinded reviewers.Study designCross-sectional study; Level of evidence, 3.MethodsA total of 281 shoulder magnetic resonance imaging (MRI) scans obtained over 8 months were reviewed by a musculoskeletal radiologist and an orthopaedic surgeon. The mean ± SD age of the group was 49.6 ± 15.5 years, and 107 of the patients were female (38.1%). Patients were divided into 4 age groups: 35 years or younger, 36 to 50 years, 51 to 65 years, and older than 65 years. Statistical analyses were completed by use of the Fisher exact test to compare proportions of SLAP tears between age groups, odds ratios to determine the likelihood of having a SLAP tear in each age group, and a logistic regression to control for associated abnormalities.ResultsThere was a significant diffference in the proportion of SLAP tears found on the MRIs for each age group (P < .001). Patients were significantly more likely to have SLAP tears if aged 51 to 65 years (66.7%; odds ratio [OR], 2.00; 95% CI, 1.27-3.15) and if older than 65 years (81.2%; OR, 4.31; 95% CI, 2.36-7.88). No increased prevalence was observed in patients aged 35 years or younger (47.5%; OR, 0.91; 95% CI, 0.55-1.50) or 36 to 50 years (51.8%; OR, 1.08; 95% CI, 0.70-1.67). Logistic regression demonstrated that age was the only significant predictor for having a SLAP tear (P < .001). Kappa values were 0.46 to 0.65 between reviewers, indicating moderate to substantial agreement.ConclusionAn increasing prevalence of MRI-based SLAP tears was observed with increasing patient age. Patients older than 50 years were significantly more likely to have superior labral abnormalities regardless of other shoulder injury or disease

Rare in Burlesque: Northanger Abbey

[Extract] It has been appreciated for many years that a special part of the appeal and literary-historical significance of Northanger Abbey lies in the way the novel dramatizes and articulates the relationship between the two fictional modes it deploys: novelistic realism on the one hand and a satiric version of Gothic fiction on the other (what Reginald Farrer called in 1917 "serious drama" and "parody"). "As for the reader," Farrer concluded, "the closer his study of the dovetailing of the two motives, the profounder his pleasure."! Reflection on the moral and aesthetic effects of this dovetailing has frequently been seen as central to what Jane Austen's novel encourages and has to offer. For Walter Anderson Northanger Abbey presents a struggle between "fatuous imaginings" and "common, sensible pleasures in reading," in which Austen "intends her work ... to compete with and ultimately outstrip Gothic romances."2 For Marvin Mudrick, "The problem is to write simultaneously a Gothic novel and a realistic novel, and to gain and keep the reader's acceptance of the latter while proving that the former is false and absurd."3 In Northanger Abbey, according to Susan Morgan, "Austen mocks sentimental and gothic conventions because they are unnatural and therefore incredible.

All aboard, destination: Seamless

A key enabler for e-Research in Australia is to give researchers seamless access to resources, including each other. Significant investments have been made, and are continuing to be made, in supplying the above resources. Convergence, a key driver of current developments in telecommunications, media and information technology industries, has brought about the rapid evolution of digital, information and communications technologies and has created an environment in which the paradigms of research have changed. Convergence is not just about the technology evolution. It is about services and about new ways of doing business and of interacting with society. It has created growing demand by researchers for services including seamless access to data held in universities, publicly funded research agencies, government agencies and industry; access to data generated by scientific facilities and access to computational capability. The emergence of new services and the development of existing services are expected to provide researchers with more opportunities. They may want access from anywhere anytime to any service, independently of the technology used, or the geographical point of such access within a trusted environment. At the same time the evolution of the capability and sophistication of scientific instruments and facilities has seen an explosion in the quantum of data produced by experimentation, and the complexity of analyses conducted through data sharing. Globalisation amplifies the international dimension of convergence. The global reach of the Internet has already shown a need for international solutions to a number of key issues such as security, intellectual property rights, privacy and interoperability. The effective re-use of research data on a national basis is the primary goal of the government and institutional investments into national data infrastructure. The investments will deliver access services; and outreach services for researchers and institutions that can enhance the effective use of data within a federated research data management system. The outcome will be the ability for all researchers to identify, locate, access and analyse any available research data, regardless of origin or scale, to interface with the outside world, within trusted environments for example the Australian Access Federation. The key facilitators for this are adequate physical resources, middleware, access to data including data collection and generation; data storage and the physical management of stored data; the evolution of standards to enable data to be used and interpreted; and access regimes to permit data to be accessible. The Australian Government, in partnership with research communities, state governments and key research agencies, is working towards coordinating the advancement of Australia’s national e-Research capabilities. The timely development of these capabilities, in an increasingly competitive international environment, will entail the careful coordination and bringing together of distributed initiatives and projects already undertaken by research communities, many institutions and jurisdictions. e-Research capabilities will also underpin the implementation of the Australian Government’s Research Quality Framework (RQF). A key enabler of the RQF will be the Accessibility Framework, which will set out the principles governing the need for improved access to the outcomes and outputs of publicly-funded research. Ongoing work through the NCRIS Platforms for Collaboration capability will determine the strategic and balanced investments in system-wide infrastructure and ICT enabled services to support Australian researchers. Only by a concerted, strongly-directed, intervention-based strategy and national cooperation will the critical mass be achieved to more fully enable Australian researchers with e-Research capabilities. By combining our resources, we will enhance the chances and opportunities for our researchers in the years to come